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NUVL
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NUVLNuvalent, Inc.
$123.96$9.1B
Overview & Tools
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NUVL logo

Nuvalent, Inc.

NUVL
NASDAQ · Biotechnology
$123.96
At close - Aug 8, 4:00 PM EDT - USD
Market Cap$9.13B
P/E-21.2x
52W High$123.99
Volume-
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Accelerating Clinical R&D Drives Capital Consumption

Nuvalent is currently navigating a critical transition into late-stage clinical development, characterized by a sharp escalation in R&D spending to support its lead assets, NVL-520 and NVL-655. While the company maintains a robust equity base of $1.2 billion, ...

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsStrong
Explore valuation models
MARKET ACTION

NUVL price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

2/12 Beats

EPS beat 2 of last 12 quarters

02

Valuation risk

-167% Peers

P/E is 167% below peer median

03

Market leadership

RS 83 · Leader

High momentum (Outperforming 83% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Aug 7
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

The company remains in a pre-revenue stage with operating losses widening to $119.4 million in 2026Q1, driven by a surge in R&D expenditures from $35.6 million in 2023Q4 to $83.6 million.

Analyst Consensus+2.7% target
Hold(19 analysts)
8 Buy11 Hold0 Sell

The Bull Case

Upside Catalysts

Strong cash position

Nuvalent has a strong cash position, providing financial stability and flexibility to advance its pipeline.

Promising cancer drug pipeline

The company's pipeline includes promising cancer drugs like zidesamtinib, neladalkib, and NVL-330, offering high-risk, high-reward potential.

Durable response for neladalkib

Neladalkib has shown durable responses, which could drive significant commercial success in treating targeted cancers.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
NUVL+22.93%
S&P 500 (^GSPC)+12.39%
1-Year Return
NUVL+52.89%
S&P 500 (^GSPC)+15.77%
3-Year Return
NUVL+191.40%
S&P 500 (^GSPC)+82.78%
5-Year Return
NUVL+375.49%
S&P 500 (^GSPC)+77.55%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$425M-63.1% YoY
Free cash flow
-$275M-48.7% YoY
Operating margin
-
ROIC (TTM)-32.5%
Avg ROIC 5Y-
ROE (TTM)-36.7%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate2/12 (17%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026Latest
May 7, 2026
-$1.39-3.0%
vs -$1.35
—
vs $486,000
Q1 2026
Feb 26, 2026
-$1.29+12.8%
vs -$1.48
—
vs $7M
Q4 2025
Oct 30, 2025
-$1.70-22.3%
vs -$1.39
—
vs —
Q3 2025
Aug 7, 2025
-$1.31-3.1%
vs -$1.27
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

1 Stories
Defense World·Jul 22, 2026
Fifth Third Bancorp Acquires New Holdings in Nuvalent, Inc. $NUVL

Fifth Third Bancorp bought a new position in shares of Nuvalent, Inc. (NASDAQ: NUVL) during the first quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission. The institutional investor bought 23,621 shares of the company's stock, valued at approximately $2,420,000. Other institutional investors and hedge funds

Filtered for Nuvalent, Inc.More Headlines
04

Compare before deciding

Benchmark NUVL against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Nuvalent, Inc. (NUVL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
NUVL logoNUVLNuvalent, Inc.Current
$123.96$9.13B-21.19——-36.7%—
KROS logoKROSKeros Therapeutics, Inc.
$11.63$372.14M5.066774.96%-553.88%-21.4%—
TPST logoTPSTTempest Therapeutics, Inc.
$0.92$14.04M-0.15——-1270.11%—
MRUS logoMRUSMerus N.V.
$90.00$6.83B-26.87-12.38%-654.43%-50.62%—
ERAS logoERASErasca, Inc.
$13.95$4.84B-31.69——-80.43%—
TARS logoTARSTarsus Pharmaceuticals, Inc.
$74.29$3.2B-46.72146.71%-7.67%-13.53%—

Compare NUVL vs Peers

Nuvalent, Inc. (NUVL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KROS

Most directly comparable listed peer for NUVL.

Scale Benchmark

vs LLY

Larger-name benchmark to compare NUVL against a more recognizable public peer.

Peer Set

Compare Top 5

vs KROS, TPST, MRUS, ERAS

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

NUVL SEC Filings & Documents

Nuvalent, Inc. (NUVL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 15, 2026·SEC

Material company update

Jun 18, 2026·SEC

Material company update

Jun 9, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 27, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Oct 30, 2025·SEC

FY 2025

Aug 7, 2025·SEC

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NUVL Frequently Asked Questions

Nuvalent, Inc. (NUVL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is NUVL profitable?

Nuvalent, Inc. (NUVL) reported a net loss of $450.1M for fiscal year 2025.

Dividend & Returns
What is NUVL's return on equity?

Nuvalent, Inc. (NUVL) has a return on equity (ROE) of -36.7%. Negative ROE indicates the company is unprofitable.

What is Nuvalent, Inc.'s free cash flow?

Nuvalent, Inc. (NUVL) had negative free cash flow of $312.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in NUVL back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →