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AVTR vs WAT vs TMO vs A vs DHR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
AVTR
Avantor, Inc.

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$5.67B
5Y Perf.-56.2%
WAT
Waters Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$22.83B
5Y Perf.+75.3%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$176.36B
5Y Perf.+35.9%
A
Agilent Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$33.58B
5Y Perf.+34.6%
DHR
Danaher Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$124.33B
5Y Perf.+18.9%

AVTR vs WAT vs TMO vs A vs DHR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
AVTR logoAVTR
WAT logoWAT
TMO logoTMO
A logoA
DHR logoDHR
IndustryMedical - Instruments & SuppliesMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$5.67B$22.83B$176.36B$33.58B$124.33B
Revenue (TTM)$6.55B$3.77B$45.20B$7.07B$24.78B
Net Income (TTM)$-551M$449M$6.86B$1.29B$3.69B
Gross Margin32.1%55.0%39.4%38.8%60.7%
Operating Margin-4.3%17.1%17.8%20.6%21.0%
Forward P/E10.6x24.4x19.1x19.9x20.8x
Total Debt$3.95B$1.41B$40.85B$3.35B$18.42B
Cash & Equiv.$365M$588M$9.86B$1.79B$4.62B

AVTR vs WAT vs TMO vs A vs DHRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

AVTR
WAT
TMO
A
DHR
StockMay 20May 26Return
Avantor, Inc. (AVTR)10043.8-56.2%
Waters Corporation (WAT)100175.3+75.3%
Thermo Fisher Scien… (TMO)100135.9+35.9%
Agilent Technologie… (A)100134.6+34.6%
Danaher Corporation (DHR)100118.9+18.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: AVTR vs WAT vs TMO vs A vs DHR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: A leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Avantor, Inc. is the stronger pick specifically for valuation and capital efficiency. WAT, TMO, and DHR also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
AVTR
Avantor, Inc.
The Value Play

AVTR is the #2 pick in this set and the best alternative if value is your priority.

  • Lower P/E (10.6x vs 20.8x)
Best for: value
WAT
Waters Corporation
The Growth Play

WAT ranks third and is worth considering specifically for growth exposure.

  • Rev growth 7.0%, EPS growth 0.5%, 3Y rev CAGR 2.1%
  • 7.0% revenue growth vs AVTR's -3.4%
Best for: growth exposure
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO is the clearest fit if your priority is long-term compounding.

  • 229.1% 10Y total return vs WAT's 162.0%
  • +16.8% vs AVTR's -30.4%
Best for: long-term compounding
A
Agilent Technologies, Inc.
The Income Pick

A carries the broadest edge in this set and is the clearest fit for income & stability and valuation efficiency.

  • Dividend streak 10 yrs, beta 1.23, yield 0.8%
  • PEG 1.35 vs DHR's 34.35
  • Beta 1.23, yield 0.8%, current ratio 1.96x
  • 18.3% margin vs AVTR's -8.4%
Best for: income & stability and valuation efficiency
DHR
Danaher Corporation
The Defensive Pick

DHR is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.94, Low D/E 35.1%, current ratio 1.87x
  • Beta 0.94 vs AVTR's 1.54, lower leverage
Best for: sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthWAT logoWAT7.0% revenue growth vs AVTR's -3.4%
ValueAVTR logoAVTRLower P/E (10.6x vs 20.8x)
Quality / MarginsA logoA18.3% margin vs AVTR's -8.4%
Stability / SafetyDHR logoDHRBeta 0.94 vs AVTR's 1.54, lower leverage
DividendsA logoA0.8% yield, 10-year raise streak, vs TMO's 0.4%, (2 stocks pay no dividend)
Momentum (1Y)TMO logoTMO+16.8% vs AVTR's -30.4%
Efficiency (ROA)A logoA10.1% ROA vs AVTR's -4.6%, ROIC 13.5% vs -2.0%

AVTR vs WAT vs TMO vs A vs DHR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

AVTRAvantor, Inc.
FY 2025
Proprietary Materials And Consumables
52.6%$3.4B
Third Party Materials And Consumables
47.4%$3.1B
WATWaters Corporation
FY 2025
Waters Instrument Systems
34.8%$1.1B
Waters Service
34.1%$1.1B
Chemistry Consumables
19.9%$631M
Ta Instrument Systems
7.7%$244M
Ta Service
3.4%$108M
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
AAgilent Technologies, Inc.
FY 2025
Agilent CrossLab
41.9%$2.9B
Life Sciences and Applied Markets
39.2%$2.7B
Applied Markets
18.9%$1.3B
DHRDanaher Corporation
FY 2025
Revenue from Contract with Customer, Measurement, Recurring
81.9%$20.1B
Revenue from Contract with Customer, Measurement, Nonrecurring
18.1%$4.4B

AVTR vs WAT vs TMO vs A vs DHR — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLWATLAGGINGTMO

Income & Cash Flow (Last 12 Months)

DHR leads this category, winning 3 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 12.0x WAT's $3.8B. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to AVTR's -8.4%. On growth, WAT holds the edge at +91.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricAVTR logoAVTRAvantor, Inc.WAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…DHR logoDHRDanaher Corporati…
RevenueTrailing 12 months$6.6B$3.8B$45.2B$7.1B$24.8B
EBITDAEarnings before interest/tax$137M$953M$10.5B$1.7B$7.2B
Net IncomeAfter-tax profit-$551M$449M$6.9B$1.3B$3.7B
Free Cash FlowCash after capex$439M$264M$6.7B$993M$5.3B
Gross MarginGross profit ÷ Revenue+32.1%+55.0%+39.4%+38.8%+60.7%
Operating MarginEBIT ÷ Revenue-4.3%+17.1%+17.8%+20.6%+21.0%
Net MarginNet income ÷ Revenue-8.4%+11.9%+15.2%+18.3%+14.9%
FCF MarginFCF ÷ Revenue+6.7%+7.0%+14.9%+14.1%+21.4%
Rev. Growth (YoY)Latest quarter vs prior year0.0%+91.5%+6.2%+7.0%+3.7%
EPS Growth (YoY)Latest quarter vs prior year-32.6%-142.9%+11.3%-3.6%+9.8%
DHR leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

AVTR leads this category, winning 5 of 7 comparable metrics.

At 26.0x trailing earnings, A trades at a 26% valuation discount to DHR's 34.9x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.76x vs DHR's 34.35x — a lower PEG means you pay less per unit of expected earnings growth.

MetricAVTR logoAVTRAvantor, Inc.WAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…DHR logoDHRDanaher Corporati…
Market CapShares × price$5.7B$22.8B$176.4B$33.6B$124.3B
Enterprise ValueMkt cap + debt − cash$9.3B$23.7B$207.4B$35.1B$138.1B
Trailing P/EPrice ÷ TTM EPS-10.65x32.55x26.75x25.96x34.85x
Forward P/EPrice ÷ next-FY EPS est.10.57x24.36x19.11x19.87x20.82x
PEG RatioP/E ÷ EPS growth rate6.29x12.67x1.76x34.35x
EV / EBITDAEnterprise value multiple56.43x21.51x19.04x19.89x18.21x
Price / SalesMarket cap ÷ Revenue0.87x7.21x3.96x4.83x5.06x
Price / BookPrice ÷ Book value/share1.01x8.17x3.34x5.00x2.38x
Price / FCFMarket cap ÷ FCF11.46x42.30x28.02x29.15x23.64x
AVTR leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

WAT leads this category, winning 4 of 9 comparable metrics.

A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $-10 for AVTR. DHR carries lower financial leverage with a 0.35x debt-to-equity ratio, signaling a more conservative balance sheet compared to TMO's 0.76x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs WAT's 4/9, reflecting strong financial health.

MetricAVTR logoAVTRAvantor, Inc.WAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…DHR logoDHRDanaher Corporati…
ROE (TTM)Return on equity-9.6%+8.0%+13.2%+18.7%+7.1%
ROA (TTM)Return on assets-4.6%+4.6%+6.4%+10.1%+4.5%
ROICReturn on invested capital-2.0%+20.3%+7.5%+13.5%+5.9%
ROCEReturn on capital employed-2.4%+18.5%+9.1%+14.5%+7.0%
Piotroski ScoreFundamental quality 0–954657
Debt / EquityFinancial leverage0.71x0.55x0.76x0.50x0.35x
Net DebtTotal debt minus cash$3.6B$820M$31.0B$1.6B$13.8B
Cash & Equiv.Liquid assets$365M$588M$9.9B$1.8B$4.6B
Total DebtShort + long-term debt$3.9B$1.4B$40.9B$3.4B$18.4B
Interest CoverageEBIT ÷ Interest expense-1.55x6.72x5.89x19.53x18.13x
WAT leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

WAT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in WAT five years ago would be worth $11,133 today (with dividends reinvested), compared to $2,662 for AVTR. Over the past 12 months, TMO leads with a +16.8% total return vs AVTR's -30.4%. The 3-year compound annual growth rate (CAGR) favors WAT at 5.7% vs AVTR's -25.5% — a key indicator of consistent wealth creation.

MetricAVTR logoAVTRAvantor, Inc.WAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…DHR logoDHRDanaher Corporati…
YTD ReturnYear-to-date-27.5%-8.3%-19.8%-13.6%-23.6%
1-Year ReturnPast 12 months-30.4%+1.4%+16.8%+11.3%-8.3%
3-Year ReturnCumulative with dividends-58.6%+18.1%-11.7%-8.2%-15.5%
5-Year ReturnCumulative with dividends-73.4%+11.3%+2.8%-8.0%-21.1%
10-Year ReturnCumulative with dividends-42.7%+162.0%+229.1%+205.7%+219.3%
CAGR (3Y)Annualised 3-year return-25.5%+5.7%-4.0%-2.8%-5.5%
WAT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — WAT and DHR each lead in 1 of 2 comparable metrics.

DHR is the less volatile stock with a 0.94 beta — it tends to amplify market swings less than AVTR's 1.54 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. WAT currently trades 84.6% from its 52-week high vs AVTR's 52.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricAVTR logoAVTRAvantor, Inc.WAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…DHR logoDHRDanaher Corporati…
Beta (5Y)Sensitivity to S&P 5001.54x1.07x1.10x1.23x0.94x
52-Week HighHighest price in past year$15.93$414.15$643.99$160.27$242.80
52-Week LowLowest price in past year$7.26$275.05$385.46$104.79$172.06
% of 52W HighCurrent price vs 52-week peak+52.2%+84.6%+73.7%+74.0%+72.3%
RSI (14)Momentum oscillator 0–10058.164.943.152.533.0
Avg Volume (50D)Average daily shares traded8.9M999K1.9M2.0M4.2M
Evenly matched — WAT and DHR each lead in 1 of 2 comparable metrics.

Analyst Outlook

A leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: AVTR as "Hold", WAT as "Hold", TMO as "Buy", A as "Buy", DHR as "Buy". Consensus price targets imply 40.6% upside for DHR (target: $247) vs 14.3% for AVTR (target: $10). For income investors, A offers the higher dividend yield at 0.84% vs TMO's 0.36%.

MetricAVTR logoAVTRAvantor, Inc.WAT logoWATWaters CorporationTMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…DHR logoDHRDanaher Corporati…
Analyst RatingConsensus buy/hold/sellHoldHoldBuyBuyBuy
Price TargetConsensus 12-month target$9.50$402.57$654.67$166.00$247.00
# AnalystsCovering analysts2634423842
Dividend YieldAnnual dividend ÷ price+0.4%+0.8%+0.7%
Dividend StreakConsecutive years of raises018101
Dividend / ShareAnnual DPS$1.69$0.99$1.23
Buyback YieldShare repurchases ÷ mkt cap+1.4%+0.1%+1.7%+1.3%+2.5%
A leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

WAT leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). DHR leads in 1 (Income & Cash Flow). 1 tied.

Best OverallWaters Corporation (WAT)Leads 2 of 6 categories
Loading custom metrics...

AVTR vs WAT vs TMO vs A vs DHR: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is AVTR or WAT or TMO or A or DHR a better buy right now?

For growth investors, Waters Corporation (WAT) is the stronger pick with 7.

0% revenue growth year-over-year, versus -3. 4% for Avantor, Inc. (AVTR). Agilent Technologies, Inc. (A) offers the better valuation at 26. 0x trailing P/E (19. 9x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — AVTR or WAT or TMO or A or DHR?

On trailing P/E, Agilent Technologies, Inc.

(A) is the cheapest at 26. 0x versus Danaher Corporation at 34. 9x. On forward P/E, Avantor, Inc. is actually cheaper at 10. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 35x versus Danaher Corporation's 34. 35x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — AVTR or WAT or TMO or A or DHR?

Over the past 5 years, Waters Corporation (WAT) delivered a total return of +11.

3%, compared to -73. 4% for Avantor, Inc. (AVTR). Over 10 years, the gap is even starker: TMO returned +229. 1% versus AVTR's -42. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — AVTR or WAT or TMO or A or DHR?

By beta (market sensitivity over 5 years), Danaher Corporation (DHR) is the lower-risk stock at 0.

94β versus Avantor, Inc. 's 1. 54β — meaning AVTR is approximately 64% more volatile than DHR relative to the S&P 500. On balance sheet safety, Danaher Corporation (DHR) carries a lower debt/equity ratio of 35% versus 76% for Thermo Fisher Scientific Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — AVTR or WAT or TMO or A or DHR?

By revenue growth (latest reported year), Waters Corporation (WAT) is pulling ahead at 7.

0% versus -3. 4% for Avantor, Inc. (AVTR). On earnings-per-share growth, the picture is similar: Thermo Fisher Scientific Inc. grew EPS 7. 3% year-over-year, compared to -175. 0% for Avantor, Inc.. Over a 3-year CAGR, WAT leads at 2. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — AVTR or WAT or TMO or A or DHR?

Waters Corporation (WAT) is the more profitable company, earning 20.

3% net margin versus -8. 1% for Avantor, Inc. — meaning it keeps 20. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: WAT leads at 28. 2% versus -3. 8% for AVTR. At the gross margin level — before operating expenses — DHR leads at 60. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is AVTR or WAT or TMO or A or DHR more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 35x versus Danaher Corporation's 34. 35x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Avantor, Inc. (AVTR) trades at 10. 6x forward P/E versus 24. 4x for Waters Corporation — 13. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DHR: 40. 6% to $247. 00.

08

Which pays a better dividend — AVTR or WAT or TMO or A or DHR?

In this comparison, A (0.

8% yield), DHR (0. 7% yield), TMO (0. 4% yield) pay a dividend. AVTR, WAT do not pay a meaningful dividend and should not be held primarily for income.

09

Is AVTR or WAT or TMO or A or DHR better for a retirement portfolio?

For long-horizon retirement investors, Danaher Corporation (DHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

94), 0. 7% yield, +219. 3% 10Y return). Avantor, Inc. (AVTR) carries a higher beta of 1. 54 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (DHR: +219. 3%, AVTR: -42. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between AVTR and WAT and TMO and A and DHR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

A, DHR pay a dividend while AVTR, WAT, TMO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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