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BHVN vs KALA vs LNTH vs ABBV vs PFE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BHVN
Biohaven Ltd.

Biotechnology

HealthcareNYSE • US
Market Cap$1.03B
5Y Perf.+54.5%
KALA
KALA BIO, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$618K
5Y Perf.-99.2%
LNTH
Lantheus Holdings, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$5.92B
5Y Perf.+29.4%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+51.0%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$150.63B
5Y Perf.-39.5%

BHVN vs KALA vs LNTH vs ABBV vs PFE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BHVN logoBHVN
KALA logoKALA
LNTH logoLNTH
ABBV logoABBV
PFE logoPFE
IndustryBiotechnologyBiotechnologyDrug Manufacturers - Specialty & GenericDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$1.03B$618K$5.92B$358.42B$150.63B
Revenue (TTM)$0.00$254K$1.55B$61.16B$63.31B
Net Income (TTM)$-648M$-36M$279M$4.23B$7.49B
Gross Margin-3.1%60.5%70.2%69.3%
Operating Margin-150.6%18.8%26.7%23.4%
Forward P/E17.5x14.3x8.9x
Total Debt$279M$32M$738K$69.07B$67.42B
Cash & Equiv.$230M$51M$359M$5.23B$1.14B

BHVN vs KALA vs LNTH vs ABBV vs PFELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BHVN
KALA
LNTH
ABBV
PFE
StockSep 22May 26Return
Biohaven Ltd. (BHVN)100154.5+54.5%
KALA BIO, Inc. (KALA)1000.8-99.2%
Lantheus Holdings, … (LNTH)100129.4+29.4%
AbbVie Inc. (ABBV)100151.0+51.0%
Pfizer Inc. (PFE)10060.5-39.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: BHVN vs KALA vs LNTH vs ABBV vs PFE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: PFE leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and dividend income and shareholder returns. Lantheus Holdings, Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. KALA and ABBV also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
BHVN
Biohaven Ltd.
The Healthcare Pick

Among these 5 stocks, BHVN doesn't own a clear edge in any measured category.

Best for: healthcare exposure
KALA
KALA BIO, Inc.
The Growth Play

KALA ranks third and is worth considering specifically for growth exposure.

  • Rev growth 262.9%, EPS growth 59.8%
  • 262.9% revenue growth vs PFE's -1.6%
Best for: growth exposure
LNTH
Lantheus Holdings, Inc.
The Long-Run Compounder

LNTH is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.

  • 41.9% 10Y total return vs ABBV's 295.5%
  • Lower volatility, beta 0.47, Low D/E 0.1%, current ratio 2.70x
  • 18.0% margin vs KALA's -141.1%
  • 12.4% ROA vs KALA's -143.2%
Best for: long-term compounding and sleep-well-at-night
ABBV
AbbVie Inc.
The Defensive Choice

ABBV is the clearest fit if your priority is stability.

  • Beta 0.34 vs KALA's 2.09
Best for: stability
PFE
Pfizer Inc.
The Income Pick

PFE carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • Dividend streak 15 yrs, beta 0.54, yield 6.5%
  • Beta 0.54, yield 6.5%, current ratio 1.16x
  • Lower P/E (8.9x vs 14.3x)
  • 6.5% yield, 15-year raise streak, vs ABBV's 3.2%, (3 stocks pay no dividend)
Best for: income & stability and defensive
See the full category breakdown
CategoryWinnerWhy
GrowthKALA logoKALA262.9% revenue growth vs PFE's -1.6%
ValuePFE logoPFELower P/E (8.9x vs 14.3x)
Quality / MarginsLNTH logoLNTH18.0% margin vs KALA's -141.1%
Stability / SafetyABBV logoABBVBeta 0.34 vs KALA's 2.09
DividendsPFE logoPFE6.5% yield, 15-year raise streak, vs ABBV's 3.2%, (3 stocks pay no dividend)
Momentum (1Y)PFE logoPFE+23.7% vs KALA's -97.6%
Efficiency (ROA)LNTH logoLNTH12.4% ROA vs KALA's -143.2%

BHVN vs KALA vs LNTH vs ABBV vs PFE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BHVNBiohaven Ltd.

Segment breakdown not available.

KALAKALA BIO, Inc.

Segment breakdown not available.

LNTHLantheus Holdings, Inc.
FY 2025
Product
33.4%$1.5B
Radiopharmaceutical Oncology
21.9%$989M
PYLARIFY
21.9%$989M
Total Precision Diagnostics
10.9%$493M
DEFINITY
7.3%$330M
Techne Lite
1.9%$87M
Strategic Partnerships And Other
1.3%$59M
Other (2)
1.3%$59M
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B

BHVN vs KALA vs LNTH vs ABBV vs PFE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLNTHLAGGINGKALA

Income & Cash Flow (Last 12 Months)

ABBV leads this category, winning 5 of 6 comparable metrics.

PFE and BHVN operate at a comparable scale, with $63.3B and $0 in trailing revenue. LNTH is the more profitable business, keeping 18.0% of every revenue dollar as net income compared to KALA's -141.1%. On growth, ABBV holds the edge at +10.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBHVN logoBHVNBiohaven Ltd.KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
RevenueTrailing 12 months$0$254,000$1.5B$61.2B$63.3B
EBITDAEarnings before interest/tax-$646M-$38M$347M$24.5B$21.0B
Net IncomeAfter-tax profit-$648M-$36M$279M$4.2B$7.5B
Free Cash FlowCash after capex-$594M-$32M$372M$18.7B$9.5B
Gross MarginGross profit ÷ Revenue-3.1%+60.5%+70.2%+69.3%
Operating MarginEBIT ÷ Revenue-150.6%+18.8%+26.7%+23.4%
Net MarginNet income ÷ Revenue-141.1%+18.0%+6.9%+11.8%
FCF MarginFCF ÷ Revenue-126.3%+24.0%+30.6%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year+1.2%+10.0%+5.4%
EPS Growth (YoY)Latest quarter vs prior year+59.4%+44.6%+76.5%+57.4%-9.5%
ABBV leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

PFE leads this category, winning 4 of 6 comparable metrics.

At 19.5x trailing earnings, PFE trades at a 77% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, PFE's 10.7x EV/EBITDA is more attractive than ABBV's 15.0x.

MetricBHVN logoBHVNBiohaven Ltd.KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
Market CapShares × price$1.0B$617,676$5.9B$358.4B$150.6B
Enterprise ValueMkt cap + debt − cash$1.1B-$18M$5.6B$422.3B$216.9B
Trailing P/EPrice ÷ TTM EPS-1.42x-0.01x26.69x85.50x19.47x
Forward P/EPrice ÷ next-FY EPS est.17.52x14.28x8.94x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple14.61x14.96x10.66x
Price / SalesMarket cap ÷ Revenue3.84x5.86x2.41x
Price / BookPrice ÷ Book value/share20.12x0.04x5.72x1.74x
Price / FCFMarket cap ÷ FCF16.73x20.12x16.60x
PFE leads this category, winning 4 of 6 comparable metrics.

Profitability & Efficiency

LNTH leads this category, winning 6 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-9 for BHVN. LNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to BHVN's 5.36x. On the Piotroski fundamental quality scale (0–9), PFE scores 7/9 vs KALA's 2/9, reflecting strong financial health.

MetricBHVN logoBHVNBiohaven Ltd.KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
ROE (TTM)Return on equity-8.7%-3.9%+24.3%+62.1%+8.3%
ROA (TTM)Return on assets-138.0%-143.2%+12.4%+3.1%+3.6%
ROICReturn on invested capital-2.4%+30.6%+23.9%+7.5%
ROCEReturn on capital employed-187.2%-95.2%+17.1%+21.5%+9.0%
Piotroski ScoreFundamental quality 0–922567
Debt / EquityFinancial leverage5.36x2.62x0.00x0.78x
Net DebtTotal debt minus cash$49M-$19M-$358M$63.8B$66.3B
Cash & Equiv.Liquid assets$230M$51M$359M$5.2B$1.1B
Total DebtShort + long-term debt$279M$32M$738,000$69.1B$67.4B
Interest CoverageEBIT ÷ Interest expense-6.92x11.72x3.28x4.02x
LNTH leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

LNTH leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in LNTH five years ago would be worth $41,420 today (with dividends reinvested), compared to $3 for KALA. Over the past 12 months, PFE leads with a +23.7% total return vs KALA's -97.6%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs KALA's -82.6% — a key indicator of consistent wealth creation.

MetricBHVN logoBHVNBiohaven Ltd.KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
YTD ReturnYear-to-date-10.2%-86.6%+35.3%-10.1%+6.9%
1-Year ReturnPast 12 months-48.8%-97.6%+13.1%+11.3%+23.7%
3-Year ReturnCumulative with dividends-31.5%-99.5%-4.0%+50.4%-18.4%
5-Year ReturnCumulative with dividends+33.4%-100.0%+314.2%+101.3%-13.3%
10-Year ReturnCumulative with dividends+33.4%-100.0%+4192.5%+295.5%+29.6%
CAGR (3Y)Annualised 3-year return-11.8%-82.6%-1.4%+14.6%-6.6%
LNTH leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — LNTH and ABBV each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than KALA's 2.09 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. LNTH currently trades 97.8% from its 52-week high vs KALA's 0.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBHVN logoBHVNBiohaven Ltd.KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
Beta (5Y)Sensitivity to S&P 5001.35x2.09x0.47x0.34x0.54x
52-Week HighHighest price in past year$22.05$20.60$93.00$244.81$28.75
52-Week LowLowest price in past year$7.48$0.08$47.25$176.57$21.97
% of 52W HighCurrent price vs 52-week peak+44.1%+0.4%+97.8%+82.8%+92.1%
RSI (14)Momentum oscillator 0–10051.930.161.246.844.2
Avg Volume (50D)Average daily shares traded2.0M9.2M886K5.8M33.3M
Evenly matched — LNTH and ABBV each lead in 1 of 2 comparable metrics.

Analyst Outlook

PFE leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: BHVN as "Buy", KALA as "Buy", LNTH as "Buy", ABBV as "Buy", PFE as "Hold". Consensus price targets imply 21861.5% upside for KALA (target: $18) vs 3.0% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs ABBV's 3.24%.

MetricBHVN logoBHVNBiohaven Ltd.KALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…ABBV logoABBVAbbVie Inc.PFE logoPFEPfizer Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyHold
Price TargetConsensus 12-month target$21.29$18.25$101.00$256.64$27.27
# AnalystsCovering analysts259174139
Dividend YieldAnnual dividend ÷ price+3.2%+6.5%
Dividend StreakConsecutive years of raises01315
Dividend / ShareAnnual DPS$6.57$1.72
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+5.1%+0.3%0.0%
PFE leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

PFE leads in 2 of 6 categories (Valuation Metrics, Analyst Outlook). LNTH leads in 2 (Profitability & Efficiency, Total Returns). 1 tied.

Best OverallLantheus Holdings, Inc. (LNTH)Leads 2 of 6 categories
Loading custom metrics...

BHVN vs KALA vs LNTH vs ABBV vs PFE: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is BHVN or KALA or LNTH or ABBV or PFE a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Pfizer Inc. (PFE) offers the better valuation at 19. 5x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Biohaven Ltd. (BHVN) a "Buy" — based on 25 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — BHVN or KALA or LNTH or ABBV or PFE?

On trailing P/E, Pfizer Inc.

(PFE) is the cheapest at 19. 5x versus AbbVie Inc. at 85. 5x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x.

03

Which is the better long-term investment — BHVN or KALA or LNTH or ABBV or PFE?

Over the past 5 years, Lantheus Holdings, Inc.

(LNTH) delivered a total return of +314. 2%, compared to -100. 0% for KALA BIO, Inc. (KALA). Over 10 years, the gap is even starker: LNTH returned +41. 9% versus KALA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — BHVN or KALA or LNTH or ABBV or PFE?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus KALA BIO, Inc. 's 2. 09β — meaning KALA is approximately 519% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Lantheus Holdings, Inc. (LNTH) carries a lower debt/equity ratio of 0% versus 5% for Biohaven Ltd. — giving it more financial flexibility in a downturn.

05

Which is growing faster — BHVN or KALA or LNTH or ABBV or PFE?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: KALA BIO, Inc. grew EPS 59. 8% year-over-year, compared to -21. 8% for Lantheus Holdings, Inc.. Over a 3-year CAGR, LNTH leads at 18. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — BHVN or KALA or LNTH or ABBV or PFE?

Lantheus Holdings, Inc.

(LNTH) is the more profitable company, earning 15. 2% net margin versus -141. 1% for KALA BIO, Inc. — meaning it keeps 15. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -150. 6% for KALA. At the gross margin level — before operating expenses — PFE leads at 70. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is BHVN or KALA or LNTH or ABBV or PFE more undervalued right now?

On forward earnings alone, Pfizer Inc.

(PFE) trades at 8. 9x forward P/E versus 17. 5x for Lantheus Holdings, Inc. — 8. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KALA: 21861. 5% to $18. 25.

08

Which pays a better dividend — BHVN or KALA or LNTH or ABBV or PFE?

In this comparison, PFE (6.

5% yield), ABBV (3. 2% yield) pay a dividend. BHVN, KALA, LNTH do not pay a meaningful dividend and should not be held primarily for income.

09

Is BHVN or KALA or LNTH or ABBV or PFE better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). KALA BIO, Inc. (KALA) carries a higher beta of 2. 09 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABBV: +295. 5%, KALA: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between BHVN and KALA and LNTH and ABBV and PFE?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: BHVN is a small-cap quality compounder stock; KALA is a small-cap quality compounder stock; LNTH is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; PFE is a mid-cap income-oriented stock. ABBV, PFE pay a dividend while BHVN, KALA, LNTH do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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