Biotechnology
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5 / 10Stock Comparison
BHVN vs NKTR vs INCY vs PFE vs ABBV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
Drug Manufacturers - General
BHVN vs NKTR vs INCY vs PFE vs ABBV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $1.03B | $1.69B | $19.53B | $150.63B | $358.42B |
| Revenue (TTM) | $0.00 | $55M | $5.36B | $63.31B | $61.16B |
| Net Income (TTM) | $-648M | $-164M | $1.43B | $7.49B | $4.23B |
| Gross Margin | — | 99.6% | 91.9% | 69.3% | 70.2% |
| Operating Margin | — | -237.9% | 26.8% | 23.4% | 26.7% |
| Forward P/E | — | — | 13.1x | 8.9x | 14.3x |
| Total Debt | $279M | $149M | $69M | $67.42B | $69.07B |
| Cash & Equiv. | $230M | $15M | $3.10B | $1.14B | $5.23B |
BHVN vs NKTR vs INCY vs PFE vs ABBV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 22 | May 26 | Return |
|---|---|---|---|
| Biohaven Ltd. (BHVN) | 100 | 154.5 | +54.5% |
| Nektar Therapeutics (NKTR) | 100 | 173.7 | +73.7% |
| Incyte Corporation (INCY) | 100 | 146.7 | +46.7% |
| Pfizer Inc. (PFE) | 100 | 60.5 | -39.5% |
| AbbVie Inc. (ABBV) | 100 | 151.0 | +51.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BHVN vs NKTR vs INCY vs PFE vs ABBV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BHVN ranks third and is worth considering specifically for growth.
- 27.3% revenue growth vs NKTR's -43.9%
NKTR is the clearest fit if your priority is momentum.
- +8.2% vs BHVN's -48.8%
INCY has the current edge in this matchup, primarily because of its strength in growth exposure and sleep-well-at-night.
- Rev growth 21.2%, EPS growth 41.7%, 3Y rev CAGR 14.8%
- Lower volatility, beta 0.87, Low D/E 1.3%, current ratio 3.32x
- 26.7% margin vs NKTR's -297.1%
- 21.7% ROA vs BHVN's -138.0%, ROIC 51.1% vs -242.1%
PFE is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 15 yrs, beta 0.54, yield 6.5%
- Beta 0.54, yield 6.5%, current ratio 1.16x
- Lower P/E (8.9x vs 14.3x)
- 6.5% yield, 15-year raise streak, vs ABBV's 3.2%, (3 stocks pay no dividend)
ABBV is the clearest fit if your priority is long-term compounding.
- 295.5% 10Y total return vs INCY's 34.2%
- Beta 0.34 vs NKTR's 1.85
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 27.3% revenue growth vs NKTR's -43.9% | |
| Value | Lower P/E (8.9x vs 14.3x) | |
| Quality / Margins | 26.7% margin vs NKTR's -297.1% | |
| Stability / Safety | Beta 0.34 vs NKTR's 1.85 | |
| Dividends | 6.5% yield, 15-year raise streak, vs ABBV's 3.2%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +8.2% vs BHVN's -48.8% | |
| Efficiency (ROA) | 21.7% ROA vs BHVN's -138.0%, ROIC 51.1% vs -242.1% |
BHVN vs NKTR vs INCY vs PFE vs ABBV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
BHVN vs NKTR vs INCY vs PFE vs ABBV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INCY leads in 2 of 6 categories
PFE leads 2 • NKTR leads 1 • BHVN leads 0 • ABBV leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
INCY leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PFE and BHVN operate at a comparable scale, with $63.3B and $0 in trailing revenue. INCY is the more profitable business, keeping 26.7% of every revenue dollar as net income compared to NKTR's -3.0%. On growth, INCY holds the edge at +20.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $55M | $5.4B | $63.3B | $61.2B |
| EBITDAEarnings before interest/tax | -$646M | -$130M | $1.5B | $21.0B | $24.5B |
| Net IncomeAfter-tax profit | -$648M | -$164M | $1.4B | $7.5B | $4.2B |
| Free Cash FlowCash after capex | -$594M | -$209M | $1.5B | $9.5B | $18.7B |
| Gross MarginGross profit ÷ Revenue | — | +99.6% | +91.9% | +69.3% | +70.2% |
| Operating MarginEBIT ÷ Revenue | — | -2.4% | +26.8% | +23.4% | +26.7% |
| Net MarginNet income ÷ Revenue | — | -3.0% | +26.7% | +11.8% | +6.9% |
| FCF MarginFCF ÷ Revenue | — | -3.8% | +27.1% | +15.0% | +30.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -25.3% | +20.9% | +5.4% | +10.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +59.4% | -4.5% | +83.8% | -9.5% | +57.4% |
Valuation Metrics
PFE leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 15.3x trailing earnings, INCY trades at a 82% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, PFE's 10.7x EV/EBITDA is more attractive than ABBV's 15.0x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.0B | $1.7B | $19.5B | $150.6B | $358.4B |
| Enterprise ValueMkt cap + debt − cash | $1.1B | $1.8B | $16.5B | $216.9B | $422.3B |
| Trailing P/EPrice ÷ TTM EPS | -1.42x | -8.57x | 15.25x | 19.47x | 85.50x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 13.06x | 8.94x | 14.28x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 11.49x | 10.66x | 14.96x |
| Price / SalesMarket cap ÷ Revenue | — | 30.64x | 3.80x | 2.41x | 5.86x |
| Price / BookPrice ÷ Book value/share | 20.12x | 15.66x | 3.80x | 1.74x | — |
| Price / FCFMarket cap ÷ FCF | — | — | 14.42x | 16.60x | 20.12x |
Profitability & Efficiency
INCY leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-9 for BHVN. INCY carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to BHVN's 5.36x. On the Piotroski fundamental quality scale (0–9), INCY scores 7/9 vs NKTR's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -8.7% | -4.0% | +29.3% | +8.3% | +62.1% |
| ROA (TTM)Return on assets | -138.0% | -62.8% | +21.7% | +3.6% | +3.1% |
| ROICReturn on invested capital | -2.4% | -57.2% | +51.1% | +7.5% | +23.9% |
| ROCEReturn on capital employed | -187.2% | -55.7% | +29.0% | +9.0% | +21.5% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 | 7 | 7 | 6 |
| Debt / EquityFinancial leverage | 5.36x | 1.66x | 0.01x | 0.78x | — |
| Net DebtTotal debt minus cash | $49M | $134M | -$3.0B | $66.3B | $63.8B |
| Cash & Equiv.Liquid assets | $230M | $15M | $3.1B | $1.1B | $5.2B |
| Total DebtShort + long-term debt | $279M | $149M | $69M | $67.4B | $69.1B |
| Interest CoverageEBIT ÷ Interest expense | — | -4.74x | 759.79x | 4.02x | 3.28x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $2,765 for NKTR. Over the past 12 months, NKTR leads with a +818.2% total return vs BHVN's -48.8%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs BHVN's -11.8% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -10.2% | +92.0% | -3.6% | +6.9% | -10.1% |
| 1-Year ReturnPast 12 months | -48.8% | +818.2% | +64.2% | +23.7% | +11.3% |
| 3-Year ReturnCumulative with dividends | -31.5% | +621.8% | +48.6% | -18.4% | +50.4% |
| 5-Year ReturnCumulative with dividends | +33.4% | -72.3% | +18.2% | -13.3% | +101.3% |
| 10-Year ReturnCumulative with dividends | +33.4% | -59.1% | +34.2% | +29.6% | +295.5% |
| CAGR (3Y)Annualised 3-year return | -11.8% | +93.3% | +14.1% | -6.6% | +14.6% |
Risk & Volatility
Evenly matched — PFE and ABBV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than NKTR's 1.85 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs BHVN's 44.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.35x | 1.85x | 0.87x | 0.54x | 0.34x |
| 52-Week HighHighest price in past year | $22.05 | $109.00 | $112.29 | $28.75 | $244.81 |
| 52-Week LowLowest price in past year | $7.48 | $7.99 | $57.77 | $21.97 | $176.57 |
| % of 52W HighCurrent price vs 52-week peak | +44.1% | +76.5% | +87.1% | +92.1% | +82.8% |
| RSI (14)Momentum oscillator 0–100 | 51.9 | 53.4 | 59.4 | 44.2 | 46.8 |
| Avg Volume (50D)Average daily shares traded | 2.0M | 991K | 1.4M | 33.3M | 5.8M |
Analyst Outlook
PFE leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: BHVN as "Buy", NKTR as "Buy", INCY as "Buy", PFE as "Hold", ABBV as "Buy". Consensus price targets imply 118.7% upside for BHVN (target: $21) vs 3.0% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs ABBV's 3.24%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $21.29 | $132.83 | $109.50 | $27.27 | $256.64 |
| # AnalystsCovering analysts | 25 | 33 | 44 | 39 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +6.5% | +3.2% |
| Dividend StreakConsecutive years of raises | — | — | — | 15 | 13 |
| Dividend / ShareAnnual DPS | — | — | — | $1.72 | $6.57 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.1% | 0.0% | +0.3% |
INCY leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PFE leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.
BHVN vs NKTR vs INCY vs PFE vs ABBV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is BHVN or NKTR or INCY or PFE or ABBV a better buy right now?
For growth investors, Incyte Corporation (INCY) is the stronger pick with 21.
2% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Incyte Corporation (INCY) offers the better valuation at 15. 3x trailing P/E (13. 1x forward), making it the more compelling value choice. Analysts rate Biohaven Ltd. (BHVN) a "Buy" — based on 25 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — BHVN or NKTR or INCY or PFE or ABBV?
On trailing P/E, Incyte Corporation (INCY) is the cheapest at 15.
3x versus AbbVie Inc. at 85. 5x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — BHVN or NKTR or INCY or PFE or ABBV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -72. 3% for Nektar Therapeutics (NKTR). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus NKTR's -59. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — BHVN or NKTR or INCY or PFE or ABBV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus Nektar Therapeutics's 1. 85β — meaning NKTR is approximately 446% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Incyte Corporation (INCY) carries a lower debt/equity ratio of 1% versus 5% for Biohaven Ltd. — giving it more financial flexibility in a downturn.
05Which is growing faster — BHVN or NKTR or INCY or PFE or ABBV?
By revenue growth (latest reported year), Incyte Corporation (INCY) is pulling ahead at 21.
2% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: Incyte Corporation grew EPS 41. 7% year-over-year, compared to -12. 1% for Nektar Therapeutics. Over a 3-year CAGR, INCY leads at 14. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — BHVN or NKTR or INCY or PFE or ABBV?
Incyte Corporation (INCY) is the more profitable company, earning 25.
0% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 25. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -236. 8% for NKTR. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is BHVN or NKTR or INCY or PFE or ABBV more undervalued right now?
On forward earnings alone, Pfizer Inc.
(PFE) trades at 8. 9x forward P/E versus 14. 3x for AbbVie Inc. — 5. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for BHVN: 118. 7% to $21. 29.
08Which pays a better dividend — BHVN or NKTR or INCY or PFE or ABBV?
In this comparison, PFE (6.
5% yield), ABBV (3. 2% yield) pay a dividend. BHVN, NKTR, INCY do not pay a meaningful dividend and should not be held primarily for income.
09Is BHVN or NKTR or INCY or PFE or ABBV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Nektar Therapeutics (NKTR) carries a higher beta of 1. 85 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABBV: +295. 5%, NKTR: -59. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between BHVN and NKTR and INCY and PFE and ABBV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: BHVN is a small-cap quality compounder stock; NKTR is a small-cap quality compounder stock; INCY is a mid-cap high-growth stock; PFE is a mid-cap income-oriented stock; ABBV is a large-cap income-oriented stock. PFE, ABBV pay a dividend while BHVN, NKTR, INCY do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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