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BIAF vs GKOS vs NVCR vs HOLX vs IDXX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BIAF
bioAffinity Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$857K
5Y Perf.-97.7%
GKOS
Glaukos Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$7.85B
5Y Perf.+150.8%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-76.5%
HOLX
Hologic, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$16.97B
5Y Perf.+17.2%
IDXX
IDEXX Laboratories, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$45.45B
5Y Perf.+71.9%

BIAF vs GKOS vs NVCR vs HOLX vs IDXX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BIAF logoBIAF
GKOS logoGKOS
NVCR logoNVCR
HOLX logoHOLX
IDXX logoIDXX
IndustryMedical - Diagnostics & ResearchMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Diagnostics & Research
Market Cap$857K$7.85B$1.92B$16.97B$45.45B
Revenue (TTM)$7M$551M$674M$4.13B$4.45B
Net Income (TTM)$-15M$-189M$-173M$544M$1.10B
Gross Margin23.9%78.1%75.2%52.8%62.1%
Operating Margin-153.2%-15.6%-27.2%17.5%31.6%
Forward P/E17.2x38.3x
Total Debt$2M$140M$290M$2.63B$1.08B
Cash & Equiv.$1M$91M$103M$1.96B$180M

BIAF vs GKOS vs NVCR vs HOLX vs IDXXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BIAF
GKOS
NVCR
HOLX
IDXX
StockSep 22May 26Return
bioAffinity Technol… (BIAF)1002.3-97.7%
Glaukos Corporation (GKOS)100250.8+150.8%
NovoCure Limited (NVCR)10023.5-76.5%
Hologic, Inc. (HOLX)100117.2+17.2%
IDEXX Laboratories,… (IDXX)100171.9+71.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: BIAF vs GKOS vs NVCR vs HOLX vs IDXX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HOLX and IDXX are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. IDEXX Laboratories, Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. BIAF and GKOS also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
BIAF
bioAffinity Technologies, Inc.
The Growth Leader

BIAF ranks third and is worth considering specifically for growth.

  • 269.7% revenue growth vs HOLX's 1.7%
Best for: growth
GKOS
Glaukos Corporation
The Long-Run Compounder

GKOS is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 457.1% 10Y total return vs IDXX's 5.6%
  • Lower volatility, beta 1.20, Low D/E 21.3%, current ratio 4.69x
  • +52.0% vs BIAF's -66.8%
Best for: long-term compounding and sleep-well-at-night
NVCR
NovoCure Limited
The Healthcare Pick

Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
HOLX
Hologic, Inc.
The Income Pick

HOLX has the current edge in this matchup, primarily because of its strength in income & stability and defensive.

  • beta 0.41
  • Beta 0.41, current ratio 3.75x
  • Lower P/E (17.2x vs 38.3x)
  • Beta 0.41 vs BIAF's 2.53, lower leverage
Best for: income & stability and defensive
IDXX
IDEXX Laboratories, Inc.
The Growth Play

IDXX is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 10.4%, EPS growth 22.6%, 3Y rev CAGR 8.5%
  • 24.6% margin vs BIAF's -217.5%
  • 32.6% ROA vs BIAF's -127.7%, ROIC 42.5% vs -203.2%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBIAF logoBIAF269.7% revenue growth vs HOLX's 1.7%
ValueHOLX logoHOLXLower P/E (17.2x vs 38.3x)
Quality / MarginsIDXX logoIDXX24.6% margin vs BIAF's -217.5%
Stability / SafetyHOLX logoHOLXBeta 0.41 vs BIAF's 2.53, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)GKOS logoGKOS+52.0% vs BIAF's -66.8%
Efficiency (ROA)IDXX logoIDXX32.6% ROA vs BIAF's -127.7%, ROIC 42.5% vs -203.2%

BIAF vs GKOS vs NVCR vs HOLX vs IDXX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BIAFbioAffinity Technologies, Inc.
FY 2024
Health Care, Patient Service
100.0%$516,000
GKOSGlaukos Corporation
FY 2019
Glaucoma
97.5%$231M
Corneal Health
2.5%$6M
NVCRNovoCure Limited

Segment breakdown not available.

HOLXHologic, Inc.
FY 2025
Diagnostics
44.6%$1.8B
Breast Health
36.2%$1.5B
Gyn Surgical
16.6%$680M
Skeletal Health
2.7%$109M
IDXXIDEXX Laboratories, Inc.
FY 2025
Product
59.0%$2.5B
Service
41.0%$1.8B

BIAF vs GKOS vs NVCR vs HOLX vs IDXX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHOLXLAGGINGNVCR

Income & Cash Flow (Last 12 Months)

IDXX leads this category, winning 3 of 6 comparable metrics.

IDXX is the larger business by revenue, generating $4.4B annually — 656.1x BIAF's $7M. IDXX is the more profitable business, keeping 24.6% of every revenue dollar as net income compared to BIAF's -2.2%. On growth, GKOS holds the edge at +41.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBIAF logoBIAFbioAffinity Techn…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.IDXX logoIDXXIDEXX Laboratorie…
RevenueTrailing 12 months$7M$551M$674M$4.1B$4.4B
EBITDAEarnings before interest/tax-$10M-$40M-$165M$974M$1.5B
Net IncomeAfter-tax profit-$15M-$189M-$173M$544M$1.1B
Free Cash FlowCash after capex-$9M-$18M-$48M$1000M$845M
Gross MarginGross profit ÷ Revenue+23.9%+78.1%+75.2%+52.8%+62.1%
Operating MarginEBIT ÷ Revenue-153.2%-15.6%-27.2%+17.5%+31.6%
Net MarginNet income ÷ Revenue-2.2%-34.3%-25.7%+13.2%+24.6%
FCF MarginFCF ÷ Revenue-125.5%-3.4%-7.1%+24.2%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year-38.5%+41.2%+12.3%+2.5%+14.3%
EPS Growth (YoY)Latest quarter vs prior year+1.3%-6.3%-100.0%-9.2%+16.6%
IDXX leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

HOLX leads this category, winning 3 of 6 comparable metrics.

At 30.5x trailing earnings, HOLX trades at a 30% valuation discount to IDXX's 43.7x P/E. On an enterprise value basis, HOLX's 17.4x EV/EBITDA is more attractive than IDXX's 31.6x.

MetricBIAF logoBIAFbioAffinity Techn…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.IDXX logoIDXXIDEXX Laboratorie…
Market CapShares × price$857,186$7.9B$1.9B$17.0B$45.4B
Enterprise ValueMkt cap + debt − cash$1M$7.9B$2.1B$17.6B$46.3B
Trailing P/EPrice ÷ TTM EPS-0.09x-40.90x-13.80x30.53x43.75x
Forward P/EPrice ÷ next-FY EPS est.17.21x38.29x
PEG RatioP/E ÷ EPS growth rate3.06x
EV / EBITDAEnterprise value multiple17.39x31.60x
Price / SalesMarket cap ÷ Revenue0.09x15.47x2.92x4.14x10.56x
Price / BookPrice ÷ Book value/share0.33x11.69x5.51x3.43x28.75x
Price / FCFMarket cap ÷ FCF18.44x43.14x
HOLX leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

IDXX leads this category, winning 6 of 9 comparable metrics.

IDXX delivers a 70.9% return on equity — every $100 of shareholder capital generates $71 in annual profit, vs $-166 for BIAF. GKOS carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), HOLX scores 7/9 vs GKOS's 3/9, reflecting strong financial health.

MetricBIAF logoBIAFbioAffinity Techn…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.IDXX logoIDXXIDEXX Laboratorie…
ROE (TTM)Return on equity-165.6%-26.5%-50.8%+11.0%+70.9%
ROA (TTM)Return on assets-127.7%-20.1%-16.5%+6.1%+32.6%
ROICReturn on invested capital-2.0%-9.2%-16.4%+9.4%+42.5%
ROCEReturn on capital employed-190.8%-10.3%-28.9%+8.8%+61.4%
Piotroski ScoreFundamental quality 0–933577
Debt / EquityFinancial leverage0.58x0.21x0.85x0.52x0.67x
Net DebtTotal debt minus cash$395,903$49M$187M$667M$897M
Cash & Equiv.Liquid assets$1M$91M$103M$2.0B$180M
Total DebtShort + long-term debt$2M$140M$290M$2.6B$1.1B
Interest CoverageEBIT ÷ Interest expense-259.85x-18.69x-96.80x8.00x35.55x
IDXX leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GKOS leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in GKOS five years ago would be worth $16,155 today (with dividends reinvested), compared to $85 for BIAF. Over the past 12 months, GKOS leads with a +52.0% total return vs BIAF's -66.8%. The 3-year compound annual growth rate (CAGR) favors GKOS at 31.7% vs BIAF's -67.1% — a key indicator of consistent wealth creation.

MetricBIAF logoBIAFbioAffinity Techn…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.IDXX logoIDXXIDEXX Laboratorie…
YTD ReturnYear-to-date+73.8%+21.2%+28.3%+1.9%-14.6%
1-Year ReturnPast 12 months-66.8%+52.0%+1.1%+37.1%+17.6%
3-Year ReturnCumulative with dividends-96.4%+128.7%-75.7%-8.5%+17.9%
5-Year ReturnCumulative with dividends-99.1%+61.5%-91.3%+15.8%+5.1%
10-Year ReturnCumulative with dividends-99.1%+457.1%+30.3%+124.3%+556.2%
CAGR (3Y)Annualised 3-year return-67.1%+31.7%-37.6%-2.9%+5.6%
GKOS leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

HOLX leads this category, winning 2 of 2 comparable metrics.

HOLX is the less volatile stock with a 0.41 beta — it tends to amplify market swings less than BIAF's 2.53 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HOLX currently trades 100.0% from its 52-week high vs BIAF's 14.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBIAF logoBIAFbioAffinity Techn…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.IDXX logoIDXXIDEXX Laboratorie…
Beta (5Y)Sensitivity to S&P 5002.18x1.16x2.15x0.45x1.36x
52-Week HighHighest price in past year$15.00$146.75$20.06$76.04$769.98
52-Week LowLowest price in past year$0.69$73.16$9.82$52.81$471.74
% of 52W HighCurrent price vs 52-week peak+14.1%+91.4%+83.9%+100.0%+74.3%
RSI (14)Momentum oscillator 0–10038.263.069.869.152.1
Avg Volume (50D)Average daily shares traded10.5M678K1.5M10.0M533K
HOLX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: GKOS as "Buy", NVCR as "Buy", HOLX as "Hold", IDXX as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 3.9% for HOLX (target: $79).

MetricBIAF logoBIAFbioAffinity Techn…GKOS logoGKOSGlaukos Corporati…NVCR logoNVCRNovoCure LimitedHOLX logoHOLXHologic, Inc.IDXX logoIDXXIDEXX Laboratorie…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$146.67$33.50$79.00$747.50
# AnalystsCovering analysts24154222
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+4.4%+2.7%
Insufficient data to determine a leader in this category.
Key Takeaway

IDXX leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). HOLX leads in 2 (Valuation Metrics, Risk & Volatility).

Best OverallHologic, Inc. (HOLX)Leads 2 of 6 categories
Loading custom metrics...

BIAF vs GKOS vs NVCR vs HOLX vs IDXX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is BIAF or GKOS or NVCR or HOLX or IDXX a better buy right now?

For growth investors, bioAffinity Technologies, Inc.

(BIAF) is the stronger pick with 269. 7% revenue growth year-over-year, versus 1. 7% for Hologic, Inc. (HOLX). Hologic, Inc. (HOLX) offers the better valuation at 30. 5x trailing P/E (17. 2x forward), making it the more compelling value choice. Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — BIAF or GKOS or NVCR or HOLX or IDXX?

On trailing P/E, Hologic, Inc.

(HOLX) is the cheapest at 30. 5x versus IDEXX Laboratories, Inc. at 43. 7x. On forward P/E, Hologic, Inc. is actually cheaper at 17. 2x.

03

Which is the better long-term investment — BIAF or GKOS or NVCR or HOLX or IDXX?

Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +61.

5%, compared to -99. 1% for bioAffinity Technologies, Inc. (BIAF). Over 10 years, the gap is even starker: IDXX returned +542. 3% versus BIAF's -99. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — BIAF or GKOS or NVCR or HOLX or IDXX?

By beta (market sensitivity over 5 years), Hologic, Inc.

(HOLX) is the lower-risk stock at 0. 45β versus bioAffinity Technologies, Inc. 's 2. 18β — meaning BIAF is approximately 380% more volatile than HOLX relative to the S&P 500. On balance sheet safety, Glaukos Corporation (GKOS) carries a lower debt/equity ratio of 21% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.

05

Which is growing faster — BIAF or GKOS or NVCR or HOLX or IDXX?

By revenue growth (latest reported year), bioAffinity Technologies, Inc.

(BIAF) is pulling ahead at 269. 7% versus 1. 7% for Hologic, Inc. (HOLX). On earnings-per-share growth, the picture is similar: IDEXX Laboratories, Inc. grew EPS 22. 6% year-over-year, compared to -25. 0% for Hologic, Inc.. Over a 3-year CAGR, GKOS leads at 21. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — BIAF or GKOS or NVCR or HOLX or IDXX?

IDEXX Laboratories, Inc.

(IDXX) is the more profitable company, earning 24. 6% net margin versus -96. 6% for bioAffinity Technologies, Inc. — meaning it keeps 24. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IDXX leads at 31. 6% versus -95. 6% for BIAF. At the gross margin level — before operating expenses — GKOS leads at 77. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is BIAF or GKOS or NVCR or HOLX or IDXX more undervalued right now?

On forward earnings alone, Hologic, Inc.

(HOLX) trades at 17. 2x forward P/E versus 38. 3x for IDEXX Laboratories, Inc. — 21. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.

08

Which pays a better dividend — BIAF or GKOS or NVCR or HOLX or IDXX?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is BIAF or GKOS or NVCR or HOLX or IDXX better for a retirement portfolio?

For long-horizon retirement investors, Hologic, Inc.

(HOLX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 45), +124. 3% 10Y return). bioAffinity Technologies, Inc. (BIAF) carries a higher beta of 2. 18 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HOLX: +124. 3%, BIAF: -99. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between BIAF and GKOS and NVCR and HOLX and IDXX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: BIAF is a small-cap high-growth stock; GKOS is a small-cap high-growth stock; NVCR is a small-cap quality compounder stock; HOLX is a mid-cap quality compounder stock; IDXX is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Revenue Growth > 20%
  • Gross Margin > 46%
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  • Market Cap > $100B
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(BIAF: -38.5% · GKOS: 41.2%)

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