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Stock Comparison

BIO vs DHR vs TMO vs A

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.99B
5Y Perf.-47.3%
DHR
Danaher Corporation

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$123.80B
5Y Perf.+18.4%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$175.76B
5Y Perf.+35.4%
A
Agilent Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$33.31B
5Y Perf.+33.5%

BIO vs DHR vs TMO vs A — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BIO logoBIO
DHR logoDHR
TMO logoTMO
A logoA
IndustryMedical - DevicesMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$6.99B$123.80B$175.76B$33.31B
Revenue (TTM)$2.59B$24.78B$45.20B$7.07B
Net Income (TTM)$169M$3.69B$6.86B$1.29B
Gross Margin51.9%60.7%39.4%38.8%
Operating Margin9.2%21.0%17.8%20.6%
Forward P/E25.2x20.7x19.0x19.7x
Total Debt$1.53B$18.42B$40.85B$3.35B
Cash & Equiv.$532M$4.62B$9.86B$1.79B

BIO vs DHR vs TMO vs ALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BIO
DHR
TMO
A
StockMay 20May 26Return
Bio-Rad Laboratorie… (BIO)10052.7-47.3%
Danaher Corporation (DHR)100118.4+18.4%
Thermo Fisher Scien… (TMO)100135.4+35.4%
Agilent Technologie… (A)100133.5+33.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: BIO vs DHR vs TMO vs A

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: A leads in 4 of 7 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Thermo Fisher Scientific Inc. is the stronger pick specifically for valuation and capital efficiency and recent price momentum and sentiment. BIO also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
BIO
Bio-Rad Laboratories, Inc.
The Defensive Pick

BIO is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 0.92, Low D/E 20.5%, current ratio 5.62x
  • Beta 0.92, current ratio 5.62x
  • Beta 0.92 vs A's 1.23, lower leverage
Best for: sleep-well-at-night and defensive
DHR
Danaher Corporation
The Quality Angle

DHR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 229.1% 10Y total return vs DHR's 218.0%
  • Lower P/E (19.0x vs 20.7x), PEG 9.02 vs 34.20
  • +16.6% vs DHR's -7.2%
Best for: long-term compounding
A
Agilent Technologies, Inc.
The Income Pick

A carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 10 yrs, beta 1.23, yield 0.8%
  • Rev growth 6.7%, EPS growth 3.2%, 3Y rev CAGR 0.5%
  • PEG 1.34 vs DHR's 34.20
  • 6.7% revenue growth vs BIO's 0.7%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthA logoA6.7% revenue growth vs BIO's 0.7%
ValueTMO logoTMOLower P/E (19.0x vs 20.7x), PEG 9.02 vs 34.20
Quality / MarginsA logoA18.3% margin vs BIO's 6.5%
Stability / SafetyBIO logoBIOBeta 0.92 vs A's 1.23, lower leverage
DividendsA logoA0.8% yield, 10-year raise streak, vs TMO's 0.4%, (1 stock pays no dividend)
Momentum (1Y)TMO logoTMO+16.6% vs DHR's -7.2%
Efficiency (ROA)A logoA10.1% ROA vs BIO's 2.2%, ROIC 13.5% vs 2.6%

BIO vs DHR vs TMO vs A — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B
DHRDanaher Corporation
FY 2025
Revenue from Contract with Customer, Measurement, Recurring
81.9%$20.1B
Revenue from Contract with Customer, Measurement, Nonrecurring
18.1%$4.4B
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
AAgilent Technologies, Inc.
FY 2025
Agilent CrossLab
41.9%$2.9B
Life Sciences and Applied Markets
39.2%$2.7B
Applied Markets
18.9%$1.3B

BIO vs DHR vs TMO vs A — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBIOLAGGINGTMO

Income & Cash Flow (Last 12 Months)

DHR leads this category, winning 3 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 17.5x BIO's $2.6B. A is the more profitable business, keeping 18.3% of every revenue dollar as net income compared to BIO's 6.5%. On growth, A holds the edge at +7.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBIO logoBIOBio-Rad Laborator…DHR logoDHRDanaher Corporati…TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…
RevenueTrailing 12 months$2.6B$24.8B$45.2B$7.1B
EBITDAEarnings before interest/tax-$315M$7.2B$10.5B$1.7B
Net IncomeAfter-tax profit$169M$3.7B$6.9B$1.3B
Free Cash FlowCash after capex$357M$5.3B$6.7B$993M
Gross MarginGross profit ÷ Revenue+51.9%+60.7%+39.4%+38.8%
Operating MarginEBIT ÷ Revenue+9.2%+21.0%+17.8%+20.6%
Net MarginNet income ÷ Revenue+6.5%+14.9%+15.2%+18.3%
FCF MarginFCF ÷ Revenue+13.8%+21.4%+14.9%+14.1%
Rev. Growth (YoY)Latest quarter vs prior year+1.1%+3.7%+6.2%+7.0%
EPS Growth (YoY)Latest quarter vs prior year-9.5%+9.8%+11.3%-3.6%
DHR leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

BIO leads this category, winning 5 of 7 comparable metrics.

At 9.3x trailing earnings, BIO trades at a 73% valuation discount to DHR's 34.7x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.75x vs DHR's 34.20x — a lower PEG means you pay less per unit of expected earnings growth.

MetricBIO logoBIOBio-Rad Laborator…DHR logoDHRDanaher Corporati…TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…
Market CapShares × price$7.0B$123.8B$175.8B$33.3B
Enterprise ValueMkt cap + debt − cash$8.0B$137.6B$206.8B$34.9B
Trailing P/EPrice ÷ TTM EPS9.29x34.71x26.66x25.75x
Forward P/EPrice ÷ next-FY EPS est.25.17x20.73x19.04x19.71x
PEG RatioP/E ÷ EPS growth rate34.20x12.62x1.75x
EV / EBITDAEnterprise value multiple16.80x18.14x18.99x19.74x
Price / SalesMarket cap ÷ Revenue2.71x5.04x3.94x4.79x
Price / BookPrice ÷ Book value/share0.95x2.37x3.33x4.96x
Price / FCFMarket cap ÷ FCF18.67x23.54x27.93x28.92x
BIO leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

A leads this category, winning 5 of 9 comparable metrics.

A delivers a 18.7% return on equity — every $100 of shareholder capital generates $19 in annual profit, vs $2 for BIO. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to TMO's 0.76x. On the Piotroski fundamental quality scale (0–9), DHR scores 7/9 vs A's 5/9, reflecting strong financial health.

MetricBIO logoBIOBio-Rad Laborator…DHR logoDHRDanaher Corporati…TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…
ROE (TTM)Return on equity+2.4%+7.1%+13.2%+18.7%
ROA (TTM)Return on assets+2.2%+4.5%+6.4%+10.1%
ROICReturn on invested capital+2.6%+5.9%+7.5%+13.5%
ROCEReturn on capital employed+2.9%+7.0%+9.1%+14.5%
Piotroski ScoreFundamental quality 0–95765
Debt / EquityFinancial leverage0.21x0.35x0.76x0.50x
Net DebtTotal debt minus cash$999M$13.8B$31.0B$1.6B
Cash & Equiv.Liquid assets$532M$4.6B$9.9B$1.8B
Total DebtShort + long-term debt$1.5B$18.4B$40.9B$3.4B
Interest CoverageEBIT ÷ Interest expense-2.49x18.13x5.89x19.53x
A leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — TMO and A each lead in 3 of 6 comparable metrics.

A $10,000 investment in TMO five years ago would be worth $10,211 today (with dividends reinvested), compared to $4,301 for BIO. Over the past 12 months, TMO leads with a +16.6% total return vs DHR's -7.2%. The 3-year compound annual growth rate (CAGR) favors A at -3.1% vs BIO's -11.9% — a key indicator of consistent wealth creation.

MetricBIO logoBIOBio-Rad Laborator…DHR logoDHRDanaher Corporati…TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…
YTD ReturnYear-to-date-15.2%-23.9%-20.1%-14.3%
1-Year ReturnPast 12 months+11.9%-7.2%+16.6%+12.8%
3-Year ReturnCumulative with dividends-31.5%-15.9%-11.9%-9.0%
5-Year ReturnCumulative with dividends-57.0%-20.9%+2.1%-7.7%
10-Year ReturnCumulative with dividends+82.9%+218.0%+229.1%+202.6%
CAGR (3Y)Annualised 3-year return-11.9%-5.6%-4.2%-3.1%
Evenly matched — TMO and A each lead in 3 of 6 comparable metrics.

Risk & Volatility

BIO leads this category, winning 2 of 2 comparable metrics.

BIO is the less volatile stock with a 0.92 beta — it tends to amplify market swings less than A's 1.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIO currently trades 75.5% from its 52-week high vs DHR's 72.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBIO logoBIOBio-Rad Laborator…DHR logoDHRDanaher Corporati…TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…
Beta (5Y)Sensitivity to S&P 5000.92x0.94x1.10x1.23x
52-Week HighHighest price in past year$343.12$242.80$643.99$160.27
52-Week LowLowest price in past year$211.43$172.06$385.46$104.36
% of 52W HighCurrent price vs 52-week peak+75.5%+72.0%+73.4%+73.4%
RSI (14)Momentum oscillator 0–10035.332.339.852.2
Avg Volume (50D)Average daily shares traded306K4.1M1.9M2.0M
BIO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

A leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: BIO as "Buy", DHR as "Buy", TMO as "Buy", A as "Buy". Consensus price targets imply 41.2% upside for DHR (target: $247) vs 20.6% for BIO (target: $313). For income investors, A offers the higher dividend yield at 0.84% vs TMO's 0.36%.

MetricBIO logoBIOBio-Rad Laborator…DHR logoDHRDanaher Corporati…TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$312.50$247.00$654.67$166.00
# AnalystsCovering analysts14424238
Dividend YieldAnnual dividend ÷ price+0.7%+0.4%+0.8%
Dividend StreakConsecutive years of raises1810
Dividend / ShareAnnual DPS$1.23$1.69$0.99
Buyback YieldShare repurchases ÷ mkt cap+4.2%+2.5%+1.7%+1.3%
A leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

BIO leads in 2 of 6 categories (Valuation Metrics, Risk & Volatility). A leads in 2 (Profitability & Efficiency, Analyst Outlook). 1 tied.

Best OverallBio-Rad Laboratories, Inc. (BIO)Leads 2 of 6 categories
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BIO vs DHR vs TMO vs A: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is BIO or DHR or TMO or A a better buy right now?

For growth investors, Agilent Technologies, Inc.

(A) is the stronger pick with 6. 7% revenue growth year-over-year, versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 3x trailing P/E (25. 2x forward), making it the more compelling value choice. Analysts rate Bio-Rad Laboratories, Inc. (BIO) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — BIO or DHR or TMO or A?

On trailing P/E, Bio-Rad Laboratories, Inc.

(BIO) is the cheapest at 9. 3x versus Danaher Corporation at 34. 7x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 19. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 34x versus Danaher Corporation's 34. 20x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — BIO or DHR or TMO or A?

Over the past 5 years, Thermo Fisher Scientific Inc.

(TMO) delivered a total return of +2. 1%, compared to -57. 0% for Bio-Rad Laboratories, Inc. (BIO). Over 10 years, the gap is even starker: TMO returned +229. 1% versus BIO's +82. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — BIO or DHR or TMO or A?

By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.

(BIO) is the lower-risk stock at 0. 92β versus Agilent Technologies, Inc. 's 1. 23β — meaning A is approximately 33% more volatile than BIO relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 76% for Thermo Fisher Scientific Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — BIO or DHR or TMO or A?

By revenue growth (latest reported year), Agilent Technologies, Inc.

(A) is pulling ahead at 6. 7% versus 0. 7% for Bio-Rad Laboratories, Inc. (BIO). On earnings-per-share growth, the picture is similar: Bio-Rad Laboratories, Inc. grew EPS 142. 6% year-over-year, compared to -4. 7% for Danaher Corporation. Over a 3-year CAGR, A leads at 0. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — BIO or DHR or TMO or A?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus 14. 7% for Danaher Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: A leads at 21. 3% versus 10. 5% for BIO. At the gross margin level — before operating expenses — DHR leads at 60. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is BIO or DHR or TMO or A more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 34x versus Danaher Corporation's 34. 20x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 19. 0x forward P/E versus 25. 2x for Bio-Rad Laboratories, Inc. — 6. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DHR: 41. 2% to $247. 00.

08

Which pays a better dividend — BIO or DHR or TMO or A?

In this comparison, A (0.

8% yield), DHR (0. 7% yield), TMO (0. 4% yield) pay a dividend. BIO does not pay a meaningful dividend and should not be held primarily for income.

09

Is BIO or DHR or TMO or A better for a retirement portfolio?

For long-horizon retirement investors, Danaher Corporation (DHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

94), 0. 7% yield, +218. 0% 10Y return). Both have compounded well over 10 years (DHR: +218. 0%, TMO: +229. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between BIO and DHR and TMO and A?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: BIO is a small-cap deep-value stock; DHR is a mid-cap quality compounder stock; TMO is a mid-cap quality compounder stock; A is a mid-cap quality compounder stock. DHR, A pay a dividend while BIO, TMO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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  • Dividend Yield > 0.5%
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Stable Dividend Mega-Cap

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  • Market Cap > $100B
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A

Stable Dividend Mega-Cap

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 10%
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Beat Both

Find stocks that outperform BIO and DHR and TMO and A on the metrics below

Revenue Growth>
%
(BIO: 1.1% · DHR: 3.7%)
Net Margin>
%
(BIO: 6.5% · DHR: 14.9%)
P/E Ratio<
x
(BIO: 9.3x · DHR: 34.7x)

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