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BRTX vs MESO
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
BRTX vs MESO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $2M | $2.04B |
| Revenue (TTM) | $383K | $17M |
| Net Income (TTM) | $-13M | $-102M |
| Gross Margin | 79.6% | -208.5% |
| Operating Margin | -37.9% | -6.4% |
| Total Debt | $0.00 | $128M |
| Cash & Equiv. | $548K | $161M |
BRTX vs MESO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| BioRestorative Ther… (BRTX) | 100 | 61.2 | -38.8% |
| Mesoblast Limited (MESO) | 100 | 61.6 | -38.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: BRTX vs MESO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
BRTX is the clearest fit if your priority is growth exposure.
- Rev growth 175.0%, EPS growth 53.0%, 3Y rev CAGR 105.8%
MESO carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.70
- 5.4% 10Y total return vs BRTX's -100.0%
- Lower volatility, beta 1.70, Low D/E 21.5%, current ratio 1.99x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 191.4% revenue growth vs BRTX's 175.0% | |
| Quality / Margins | -5.9% margin vs BRTX's -33.0% | |
| Stability / Safety | Beta 1.70 vs BRTX's 2.21 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +45.3% vs BRTX's -86.2% | |
| Efficiency (ROA) | -13.0% ROA vs BRTX's -224.5%, ROIC -8.5% vs -100.4% |
BRTX vs MESO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
BRTX vs MESO — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
MESO leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MESO is the larger business by revenue, generating $17M annually — 44.9x BRTX's $383,400. MESO is the more profitable business, keeping -5.9% of every revenue dollar as net income compared to BRTX's -33.0%. On growth, MESO holds the edge at +4.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $383,400 | $17M |
| EBITDAEarnings before interest/tax | -$14M | -$106M |
| Net IncomeAfter-tax profit | -$13M | -$102M |
| Free Cash FlowCash after capex | -$11M | -$49M |
| Gross MarginGross profit ÷ Revenue | +79.6% | -2.1% |
| Operating MarginEBIT ÷ Revenue | -37.9% | -6.4% |
| Net MarginNet income ÷ Revenue | -33.0% | -5.9% |
| FCF MarginFCF ÷ Revenue | -28.1% | -2.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -94.9% | +4.6% |
| EPS Growth (YoY)Latest quarter vs prior year | -153.8% | +16.0% |
Valuation Metrics
BRTX leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $2M | $2.0B |
| Enterprise ValueMkt cap + debt − cash | $1M | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | -0.21x | -18.82x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 4.87x | 118.61x |
| Price / BookPrice ÷ Book value/share | 0.22x | 3.20x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
MESO leads this category, winning 6 of 7 comparable metrics.
Profitability & Efficiency
MESO delivers a -17.1% return on equity — every $100 of shareholder capital generates $-17 in annual profit, vs $-6 for BRTX. On the Piotroski fundamental quality scale (0–9), MESO scores 5/9 vs BRTX's 2/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -5.7% | -17.1% |
| ROA (TTM)Return on assets | -2.2% | -13.0% |
| ROICReturn on invested capital | -100.4% | -8.5% |
| ROCEReturn on capital employed | -124.7% | -9.8% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 5 |
| Debt / EquityFinancial leverage | — | 0.21x |
| Net DebtTotal debt minus cash | -$547,890 | -$33M |
| Cash & Equiv.Liquid assets | $547,890 | $161M |
| Total DebtShort + long-term debt | $0 | $128M |
| Interest CoverageEBIT ÷ Interest expense | — | -5.84x |
Total Returns (Dividends Reinvested)
MESO leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MESO five years ago would be worth $11,181 today (with dividends reinvested), compared to $67 for BRTX. Over the past 12 months, MESO leads with a +45.3% total return vs BRTX's -86.2%. The 3-year compound annual growth rate (CAGR) favors MESO at 32.3% vs BRTX's -63.9% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -79.9% | -12.9% |
| 1-Year ReturnPast 12 months | -86.2% | +45.3% |
| 3-Year ReturnCumulative with dividends | -95.3% | +131.8% |
| 5-Year ReturnCumulative with dividends | -99.3% | +11.8% |
| 10-Year ReturnCumulative with dividends | -100.0% | +5.4% |
| CAGR (3Y)Annualised 3-year return | -63.9% | +32.3% |
Risk & Volatility
MESO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
MESO is the less volatile stock with a 1.70 beta — it tends to amplify market swings less than BRTX's 2.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MESO currently trades 73.5% from its 52-week high vs BRTX's 11.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.21x | 1.70x |
| 52-Week HighHighest price in past year | $2.05 | $21.50 |
| 52-Week LowLowest price in past year | $0.19 | $9.88 |
| % of 52W HighCurrent price vs 52-week peak | +11.9% | +73.5% |
| RSI (14)Momentum oscillator 0–100 | 49.3 | 53.5 |
| Avg Volume (50D)Average daily shares traded | 5.7M | 256K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $11.50 |
| # AnalystsCovering analysts | — | 11 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
MESO leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BRTX leads in 1 (Valuation Metrics).
BRTX vs MESO: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is BRTX or MESO a better buy right now?
For growth investors, Mesoblast Limited (MESO) is the stronger pick with 191.
4% revenue growth year-over-year, versus 175. 0% for BioRestorative Therapies, Inc. (BRTX). Analysts rate Mesoblast Limited (MESO) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — BRTX or MESO?
Over the past 5 years, Mesoblast Limited (MESO) delivered a total return of +11.
8%, compared to -99. 3% for BioRestorative Therapies, Inc. (BRTX). Over 10 years, the gap is even starker: MESO returned +5. 4% versus BRTX's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — BRTX or MESO?
By beta (market sensitivity over 5 years), Mesoblast Limited (MESO) is the lower-risk stock at 1.
70β versus BioRestorative Therapies, Inc. 's 2. 21β — meaning BRTX is approximately 30% more volatile than MESO relative to the S&P 500.
04Which is growing faster — BRTX or MESO?
By revenue growth (latest reported year), Mesoblast Limited (MESO) is pulling ahead at 191.
4% versus 175. 0% for BioRestorative Therapies, Inc. (BRTX). On earnings-per-share growth, the picture is similar: BioRestorative Therapies, Inc. grew EPS 53. 0% year-over-year, compared to 5. 6% for Mesoblast Limited. Over a 3-year CAGR, BRTX leads at 105. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — BRTX or MESO?
Mesoblast Limited (MESO) is the more profitable company, earning -593.
9% net margin versus -22. 4% for BioRestorative Therapies, Inc. — meaning it keeps -593. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MESO leads at -363. 1% versus -28. 8% for BRTX. At the gross margin level — before operating expenses — BRTX leads at 93. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — BRTX or MESO?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is BRTX or MESO better for a retirement portfolio?
For long-horizon retirement investors, Mesoblast Limited (MESO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding.
BioRestorative Therapies, Inc. (BRTX) carries a higher beta of 2. 21 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (MESO: +5. 4%, BRTX: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between BRTX and MESO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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