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Stock Comparison

BTAI vs PTCT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BTAI
BioXcel Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3M
5Y Perf.-99.8%
PTCT
PTC Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.35B
5Y Perf.+27.2%

BTAI vs PTCT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BTAI logoBTAI
PTCT logoPTCT
IndustryBiotechnologyBiotechnology
Market Cap$3M$5.35B
Revenue (TTM)$752K$827M
Net Income (TTM)$-68M$-187M
Gross Margin-38.2%49.7%
Operating Margin-67.0%-8.3%
Forward P/E8.3x
Total Debt$103M$492M
Cash & Equiv.$30M$985M

BTAI vs PTCTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BTAI
PTCT
StockMay 20May 26Return
BioXcel Therapeutic… (BTAI)1000.2-99.8%
PTC Therapeutics, I… (PTCT)100127.2+27.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: BTAI vs PTCT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: PTCT leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. As sector peers, any of these can serve as alternatives in the same allocation.
BTAI
BioXcel Therapeutics, Inc.
The Growth Angle

In this particular matchup, BTAI is outpaced on most metrics by others in the set.

Best for: healthcare exposure
PTCT
PTC Therapeutics, Inc.
The Income Pick

PTCT carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 1.13
  • Rev growth 114.5%, EPS growth 264.5%, 3Y rev CAGR 35.3%
  • 7.3% 10Y total return vs BTAI's -99.3%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthPTCT logoPTCT114.5% revenue growth vs BTAI's 64.2%
Quality / MarginsPTCT logoPTCT-22.6% margin vs BTAI's -90.7%
Stability / SafetyPTCT logoPTCTBeta 1.13 vs BTAI's 2.64
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)PTCT logoPTCT+58.2% vs BTAI's -19.0%
Efficiency (ROA)PTCT logoPTCT-6.8% ROA vs BTAI's -152.3%

BTAI vs PTCT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BTAIBioXcel Therapeutics, Inc.

Segment breakdown not available.

PTCTPTC Therapeutics, Inc.
FY 2025
Collaboration and License Revenue
54.6%$998M
Product
32.1%$587M
Royalty
13.4%$244M

BTAI vs PTCT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLPTCTLAGGINGBTAI

Income & Cash Flow (Last 12 Months)

PTCT leads this category, winning 4 of 6 comparable metrics.

PTCT is the larger business by revenue, generating $827M annually — 1099.9x BTAI's $752,000. PTCT is the more profitable business, keeping -22.6% of every revenue dollar as net income compared to BTAI's -90.7%. On growth, BTAI holds the edge at -54.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBTAI logoBTAIBioXcel Therapeut…PTCT logoPTCTPTC Therapeutics,…
RevenueTrailing 12 months$752,000$827M
EBITDAEarnings before interest/tax-$50M-$37M
Net IncomeAfter-tax profit-$68M-$187M
Free Cash FlowCash after capex-$58M-$229M
Gross MarginGross profit ÷ Revenue-38.2%+49.7%
Operating MarginEBIT ÷ Revenue-67.0%-8.3%
Net MarginNet income ÷ Revenue-90.7%-22.6%
FCF MarginFCF ÷ Revenue-77.4%-27.7%
Rev. Growth (YoY)Latest quarter vs prior year-54.2%-76.8%
EPS Growth (YoY)Latest quarter vs prior year+57.7%-100.3%
PTCT leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

BTAI leads this category, winning 2 of 2 comparable metrics.
MetricBTAI logoBTAIBioXcel Therapeut…PTCT logoPTCTPTC Therapeutics,…
Market CapShares × price$3M$5.3B
Enterprise ValueMkt cap + debt − cash$76M$4.9B
Trailing P/EPrice ÷ TTM EPS-0.05x8.29x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple5.42x
Price / SalesMarket cap ÷ Revenue1.39x3.09x
Price / BookPrice ÷ Book value/share
Price / FCFMarket cap ÷ FCF7.61x
BTAI leads this category, winning 2 of 2 comparable metrics.

Profitability & Efficiency

PTCT leads this category, winning 5 of 6 comparable metrics.

On the Piotroski fundamental quality scale (0–9), PTCT scores 7/9 vs BTAI's 2/9, reflecting strong financial health.

MetricBTAI logoBTAIBioXcel Therapeut…PTCT logoPTCTPTC Therapeutics,…
ROE (TTM)Return on equity
ROA (TTM)Return on assets-152.3%-6.8%
ROICReturn on invested capital
ROCEReturn on capital employed-2.2%+55.9%
Piotroski ScoreFundamental quality 0–927
Debt / EquityFinancial leverage
Net DebtTotal debt minus cash$73M-$492M
Cash & Equiv.Liquid assets$30M$985M
Total DebtShort + long-term debt$103M$492M
Interest CoverageEBIT ÷ Interest expense-4.09x-1.67x
PTCT leads this category, winning 5 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

PTCT leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in PTCT five years ago would be worth $16,026 today (with dividends reinvested), compared to $25 for BTAI. Over the past 12 months, PTCT leads with a +58.2% total return vs BTAI's -19.0%. The 3-year compound annual growth rate (CAGR) favors PTCT at 5.1% vs BTAI's -85.7% — a key indicator of consistent wealth creation.

MetricBTAI logoBTAIBioXcel Therapeut…PTCT logoPTCTPTC Therapeutics,…
YTD ReturnYear-to-date-27.1%-16.0%
1-Year ReturnPast 12 months-19.0%+58.2%
3-Year ReturnCumulative with dividends-99.7%+16.1%
5-Year ReturnCumulative with dividends-99.7%+60.3%
10-Year ReturnCumulative with dividends-99.3%+733.2%
CAGR (3Y)Annualised 3-year return-85.7%+5.1%
PTCT leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

PTCT leads this category, winning 2 of 2 comparable metrics.

PTCT is the less volatile stock with a 1.13 beta — it tends to amplify market swings less than BTAI's 2.64 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PTCT currently trades 73.7% from its 52-week high vs BTAI's 15.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBTAI logoBTAIBioXcel Therapeut…PTCT logoPTCTPTC Therapeutics,…
Beta (5Y)Sensitivity to S&P 5002.64x1.13x
52-Week HighHighest price in past year$8.08$87.50
52-Week LowLowest price in past year$1.01$37.94
% of 52W HighCurrent price vs 52-week peak+15.3%+73.7%
RSI (14)Momentum oscillator 0–10057.045.3
Avg Volume (50D)Average daily shares traded1.9M1.0M
PTCT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.
MetricBTAI logoBTAIBioXcel Therapeut…PTCT logoPTCTPTC Therapeutics,…
Analyst RatingConsensus buy/hold/sellBuy
Price TargetConsensus 12-month target$89.67
# AnalystsCovering analysts26
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

PTCT leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BTAI leads in 1 (Valuation Metrics).

Best OverallPTC Therapeutics, Inc. (PTCT)Leads 4 of 6 categories
Loading custom metrics...

BTAI vs PTCT: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is BTAI or PTCT a better buy right now?

For growth investors, PTC Therapeutics, Inc.

(PTCT) is the stronger pick with 114. 5% revenue growth year-over-year, versus 64. 2% for BioXcel Therapeutics, Inc. (BTAI). PTC Therapeutics, Inc. (PTCT) offers the better valuation at 8. 3x trailing P/E, making it the more compelling value choice. Analysts rate PTC Therapeutics, Inc. (PTCT) a "Buy" — based on 26 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — BTAI or PTCT?

Over the past 5 years, PTC Therapeutics, Inc.

(PTCT) delivered a total return of +60. 3%, compared to -99. 7% for BioXcel Therapeutics, Inc. (BTAI). Over 10 years, the gap is even starker: PTCT returned +733. 2% versus BTAI's -99. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — BTAI or PTCT?

By beta (market sensitivity over 5 years), PTC Therapeutics, Inc.

(PTCT) is the lower-risk stock at 1. 13β versus BioXcel Therapeutics, Inc. 's 2. 64β — meaning BTAI is approximately 133% more volatile than PTCT relative to the S&P 500.

04

Which is growing faster — BTAI or PTCT?

By revenue growth (latest reported year), PTC Therapeutics, Inc.

(PTCT) is pulling ahead at 114. 5% versus 64. 2% for BioXcel Therapeutics, Inc. (BTAI). On earnings-per-share growth, the picture is similar: PTC Therapeutics, Inc. grew EPS 264. 5% year-over-year, compared to 76. 1% for BioXcel Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — BTAI or PTCT?

PTC Therapeutics, Inc.

(PTCT) is the more profitable company, earning 39. 4% net margin versus -26. 3% for BioXcel Therapeutics, Inc. — meaning it keeps 39. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PTCT leads at 49. 5% versus -29. 7% for BTAI. At the gross margin level — before operating expenses — PTCT leads at 95. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — BTAI or PTCT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is BTAI or PTCT better for a retirement portfolio?

For long-horizon retirement investors, PTC Therapeutics, Inc.

(PTCT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 13), +733. 2% 10Y return). BioXcel Therapeutics, Inc. (BTAI) carries a higher beta of 2. 64 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PTCT: +733. 2%, BTAI: -99. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between BTAI and PTCT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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BTAI

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  • Market Cap > $100B
  • Gross Margin > 29%
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