Biotechnology
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CAPR vs SRPT vs CRSP vs EDIT vs NTLA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
CAPR vs SRPT vs CRSP vs EDIT vs NTLA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1.55B | $2.18B | $5.06B | $297M | $1.62B |
| Revenue (TTM) | $11M | $2.18B | $4M | $0.00 | $68M |
| Net Income (TTM) | $-82M | $65M | $-569M | $-160M | $-413M |
| Gross Margin | -5.8% | 34.4% | -41.7% | — | -25.6% |
| Operating Margin | -7.8% | -1.9% | -134.1% | — | -6.5% |
| Forward P/E | — | 6.9x | — | — | — |
| Total Debt | $1M | $1.04B | $395M | $18M | $93M |
| Cash & Equiv. | $11M | $801M | $355M | $147M | $155M |
CAPR vs SRPT vs CRSP vs EDIT vs NTLA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Capricor Therapeuti… (CAPR) | 100 | 731.5 | +631.5% |
| Sarepta Therapeutic… (SRPT) | 100 | 13.7 | -86.3% |
| CRISPR Therapeutics… (CRSP) | 100 | 81.2 | -18.8% |
| Editas Medicine, In… (EDIT) | 100 | 11.2 | -88.8% |
| Intellia Therapeuti… (NTLA) | 100 | 78.3 | -21.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CAPR vs SRPT vs CRSP vs EDIT vs NTLA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CAPR is the #2 pick in this set and the best alternative if momentum is your priority.
- +392.6% vs SRPT's -43.4%
SRPT carries the broadest edge in this set and is the clearest fit for quality and efficiency.
- 3.0% margin vs CRSP's -138.6%
- 1.9% ROA vs EDIT's -74.2%
CRSP ranks third and is worth considering specifically for income & stability and long-term compounding.
- beta 1.93
- 272.0% 10Y total return vs CAPR's -4.7%
- Lower volatility, beta 1.93, Low D/E 20.5%, current ratio 13.32x
- Beta 1.93, current ratio 13.32x
Among these 5 stocks, EDIT doesn't own a clear edge in any measured category.
NTLA is the clearest fit if your priority is growth exposure.
- Rev growth 16.9%, EPS growth 27.4%, 3Y rev CAGR 9.1%
- 16.9% revenue growth vs EDIT's -100.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 16.9% revenue growth vs EDIT's -100.0% | |
| Quality / Margins | 3.0% margin vs CRSP's -138.6% | |
| Stability / Safety | Beta 1.93 vs EDIT's 2.52, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +392.6% vs SRPT's -43.4% | |
| Efficiency (ROA) | 1.9% ROA vs EDIT's -74.2% |
CAPR vs SRPT vs CRSP vs EDIT vs NTLA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
CAPR vs SRPT vs CRSP vs EDIT vs NTLA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
SRPT leads in 3 of 6 categories
CAPR leads 1 • CRSP leads 0 • EDIT leads 0 • NTLA leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
SRPT leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
SRPT and EDIT operate at a comparable scale, with $2.2B and $0 in trailing revenue. SRPT is the more profitable business, keeping 3.0% of every revenue dollar as net income compared to CRSP's -138.6%. On growth, NTLA holds the edge at +78.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $11M | $2.2B | $4M | $0 | $68M |
| EBITDAEarnings before interest/tax | -$85M | -$6M | -$535M | $0 | -$431M |
| Net IncomeAfter-tax profit | -$82M | $65M | -$569M | -$160M | -$413M |
| Free Cash FlowCash after capex | -$45M | $107M | -$401M | -$166M | -$396M |
| Gross MarginGross profit ÷ Revenue | -5.8% | +34.4% | -41.7% | — | -25.6% |
| Operating MarginEBIT ÷ Revenue | -7.8% | -1.9% | -134.1% | — | -6.5% |
| Net MarginNet income ÷ Revenue | -7.4% | +3.0% | -138.6% | — | -6.1% |
| FCF MarginFCF ÷ Revenue | -4.0% | +4.9% | -97.8% | — | -5.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | -1.9% | +68.6% | -151.6% | +78.8% |
| EPS Growth (YoY)Latest quarter vs prior year | -42.1% | +162.6% | +19.0% | +105.5% | +34.6% |
Valuation Metrics
SRPT leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.6B | $2.2B | $5.1B | $297M | $1.6B |
| Enterprise ValueMkt cap + debt − cash | $1.5B | $2.4B | $5.1B | $168M | $1.6B |
| Trailing P/EPrice ÷ TTM EPS | -29.51x | -2.92x | -8.10x | -1.68x | -3.60x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 6.93x | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 69.67x | 0.99x | 1440.41x | — | 23.93x |
| Price / BookPrice ÷ Book value/share | 8.22x | 1.91x | 2.45x | 9.85x | 2.21x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
SRPT leads this category, winning 4 of 8 comparable metrics.
Profitability & Efficiency
SRPT delivers a 4.9% return on equity — every $100 of shareholder capital generates $5 in annual profit, vs $-5 for EDIT. CAPR carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to SRPT's 0.91x. On the Piotroski fundamental quality scale (0–9), CAPR scores 4/9 vs EDIT's 1/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -97.8% | +4.9% | -30.9% | -5.2% | -56.6% |
| ROA (TTM)Return on assets | -64.8% | +1.9% | -24.5% | -74.2% | -45.2% |
| ROICReturn on invested capital | -43.8% | -31.4% | -22.3% | — | -44.0% |
| ROCEReturn on capital employed | -48.1% | -24.0% | -26.6% | — | -48.5% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 1 | 1 | 4 |
| Debt / EquityFinancial leverage | 0.01x | 0.91x | 0.21x | 0.66x | 0.14x |
| Net DebtTotal debt minus cash | -$10M | $238M | $40M | -$129M | -$62M |
| Cash & Equiv.Liquid assets | $11M | $801M | $355M | $147M | $155M |
| Total DebtShort + long-term debt | $1M | $1.0B | $395M | $18M | $93M |
| Interest CoverageEBIT ÷ Interest expense | — | -14.00x | — | — | — |
Total Returns (Dividends Reinvested)
CAPR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CAPR five years ago would be worth $97,810 today (with dividends reinvested), compared to $888 for EDIT. Over the past 12 months, CAPR leads with a +392.6% total return vs SRPT's -43.4%. The 3-year compound annual growth rate (CAGR) favors CAPR at 105.7% vs SRPT's -45.3% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +19.9% | -2.4% | -2.5% | +47.8% | +48.9% |
| 1-Year ReturnPast 12 months | +392.6% | -43.4% | +53.1% | +127.8% | +88.1% |
| 3-Year ReturnCumulative with dividends | +770.3% | -83.6% | -6.3% | -68.5% | -68.3% |
| 5-Year ReturnCumulative with dividends | +878.1% | -72.1% | -51.3% | -91.1% | -79.8% |
| 10-Year ReturnCumulative with dividends | -4.7% | +18.0% | +272.0% | -90.0% | -42.9% |
| CAGR (3Y)Annualised 3-year return | +105.7% | -45.3% | -2.2% | -32.0% | -31.8% |
Risk & Volatility
Evenly matched — CAPR and CRSP each lead in 1 of 2 comparable metrics.
Risk & Volatility
CRSP is the less volatile stock with a 1.93 beta — it tends to amplify market swings less than EDIT's 2.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CAPR currently trades 84.1% from its 52-week high vs SRPT's 47.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.97x | 2.02x | 1.93x | 2.52x | 2.37x |
| 52-Week HighHighest price in past year | $40.37 | $44.14 | $78.48 | $4.54 | $28.25 |
| 52-Week LowLowest price in past year | $4.30 | $10.42 | $33.50 | $1.29 | $6.83 |
| % of 52W HighCurrent price vs 52-week peak | +84.1% | +47.1% | +66.8% | +66.7% | +48.5% |
| RSI (14)Momentum oscillator 0–100 | 55.2 | 63.4 | 55.5 | 57.5 | 50.4 |
| Avg Volume (50D)Average daily shares traded | 1.2M | 3.0M | 2.0M | 1.6M | 5.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: CAPR as "Buy", SRPT as "Buy", CRSP as "Buy", EDIT as "Buy", NTLA as "Buy". Consensus price targets imply 98.0% upside for EDIT (target: $6) vs 18.4% for SRPT (target: $25).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $47.75 | $24.63 | $63.00 | $6.00 | $20.88 |
| # AnalystsCovering analysts | 10 | 54 | 38 | 25 | 39 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.1% | 0.0% | 0.0% | 0.0% |
SRPT leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CAPR leads in 1 (Total Returns). 1 tied.
CAPR vs SRPT vs CRSP vs EDIT vs NTLA: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is CAPR or SRPT or CRSP or EDIT or NTLA a better buy right now?
For growth investors, Intellia Therapeutics, Inc.
(NTLA) is the stronger pick with 16. 9% revenue growth year-over-year, versus -100. 0% for Editas Medicine, Inc. (EDIT). Analysts rate Capricor Therapeutics, Inc. (CAPR) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CAPR or SRPT or CRSP or EDIT or NTLA?
Over the past 5 years, Capricor Therapeutics, Inc.
(CAPR) delivered a total return of +878. 1%, compared to -91. 1% for Editas Medicine, Inc. (EDIT). Over 10 years, the gap is even starker: CRSP returned +272. 0% versus EDIT's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CAPR or SRPT or CRSP or EDIT or NTLA?
By beta (market sensitivity over 5 years), CRISPR Therapeutics AG (CRSP) is the lower-risk stock at 1.
93β versus Editas Medicine, Inc. 's 2. 52β — meaning EDIT is approximately 31% more volatile than CRSP relative to the S&P 500. On balance sheet safety, Capricor Therapeutics, Inc. (CAPR) carries a lower debt/equity ratio of 1% versus 91% for Sarepta Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CAPR or SRPT or CRSP or EDIT or NTLA?
By revenue growth (latest reported year), Intellia Therapeutics, Inc.
(NTLA) is pulling ahead at 16. 9% versus -100. 0% for Editas Medicine, Inc. (EDIT). On earnings-per-share growth, the picture is similar: Editas Medicine, Inc. grew EPS 37. 5% year-over-year, compared to -404. 7% for Sarepta Therapeutics, Inc.. Over a 3-year CAGR, CAPR leads at 349. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CAPR or SRPT or CRSP or EDIT or NTLA?
Editas Medicine, Inc.
(EDIT) is the more profitable company, earning 0. 0% net margin versus -165. 7% for CRISPR Therapeutics AG — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EDIT leads at 0. 0% versus -161. 9% for CRSP. At the gross margin level — before operating expenses — NTLA leads at 76. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is CAPR or SRPT or CRSP or EDIT or NTLA more undervalued right now?
Analyst consensus price targets imply the most upside for EDIT: 98.
0% to $6. 00.
07Which pays a better dividend — CAPR or SRPT or CRSP or EDIT or NTLA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is CAPR or SRPT or CRSP or EDIT or NTLA better for a retirement portfolio?
For long-horizon retirement investors, CRISPR Therapeutics AG (CRSP) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+272.
0% 10Y return). Editas Medicine, Inc. (EDIT) carries a higher beta of 2. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CRSP: +272. 0%, EDIT: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between CAPR and SRPT and CRSP and EDIT and NTLA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CAPR is a small-cap quality compounder stock; SRPT is a small-cap high-growth stock; CRSP is a small-cap quality compounder stock; EDIT is a small-cap quality compounder stock; NTLA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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