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Sarepta Therapeutics, Inc. (SRPT) Total Return Calculator with Dividends Reinvested

Sarepta Therapeutics, Inc.

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The total return for Sarepta Therapeutics, Inc. (SRPT) stock is -65.77% over the past 12 months. So far it's up 2.25% this year. The 5-year total return is -70.06%, meaning $10,000 invested in SRPT stock 5 years ago would be worth $2,994 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in SRPT 1 year ago, it would be worth $4,661 today — you'd have lost $5,339.

With Dividends Reinvested$4,661-53.39%

Price Only (No DRIP)$4,661-53.39%

Period2025-05-06 → 2026-05-05

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in SRPT

1Y$3,423-$6,577 (-65.8%)-65.8% CAGR

3Y$1,663-$8,337 (-83.4%)-45.0% CAGR

5Y$2,994-$7,006 (-70.1%)-21.4% CAGR

10Y$13,001+$3,001 (+30.0%)2.7% CAGR

15Y$21,617+$11,617 (+116.2%)5.3% CAGR

20Y$5,839-$4,161 (-41.6%)-2.7% CAGR

30Y$5,587-$4,413 (-44.1%)-1.9% CAGR

Sarepta Therapeutics, Inc. did not pay dividends during this period. Total return = price return.

Loading SRPT total return...

As of 2026-05-06

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	+2.25%	—	+2.25%	—	$10,225
1Y	-65.77%	-65.77%	-65.77%	—	$3,423
3Y	-83.37%	-45.00%	-83.37%	—	$1,663
5Y	-70.06%	-21.43%	-70.06%	—	$2,994
10Y	+30.01%	2.66%	+30.01%	—	$13,001
15Y	+116.17%	5.27%	+116.17%	—	$21,617
20Y	-41.61%	-2.65%	-41.61%	—	$5,839
30Y	-44.13%	-1.92%	-44.13%	—	$5,587

Risk & Highlights

Best Year+481.08%2012

Worst Year-82.66%2025

Max Drawdown-81.26%2025-05-05 → 2025-07-25

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-21.35%	-21.35%	—	+0.41%	-21.8pp
2025	-82.66%	-82.66%	—	+16.64%	-99.3pp
2024	+26.38%	+26.38%	—	+24.00%	+2.4pp
2023	-22.76%	-22.76%	—	+24.81%	-47.6pp
2022	+43.31%	+43.31%	—	-19.95%	+63.3pp

SRPT underperformed the S&P 500 by 94.21pp over the past year (-65.77% vs +28.44%).

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SRPT Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
SRPTSarepta Therapeutics, Inc.	$2.3B	-4.4%	+2.3%	-65.8%	—	-83.4%	-70.1%	+30.0%
BMRNBioMarin Pharmaceutical Inc.	$10.2B	-5.3%	-10.4%	-14.2%	—	-44.9%	-31.5%	-34.1%
ALNYAlnylam Pharmaceuticals, Inc.	$40.2B	-8.8%	-24.8%	+10.1%	—	+42.0%	+127.0%	+412.7%
RAREUltragenyx Pharmaceutical Inc.	$2.5B	+9.4%	+6.0%	-35.7%	—	-47.0%	-76.4%	-60.0%
IONSIonis Pharmaceuticals, Inc.	$12.4B	+1.2%	-5.5%	+123.6%	—	+107.9%	+88.6%	+115.6%
FOLDAmicus Therapeutics, Inc.	$4.5B	+0.3%	+1.5%	+121.9%	—	+19.3%	+51.1%	+121.9%
KRYSKrystal Biotech, Inc.	$8.4B	+8.7%	+15.3%	+75.3%	—	+237.8%	+296.0%	+2574.5%
CRSPCRISPR Therapeutics AG	$4.9B	+6.6%	-2.6%	+39.2%	—	-6.1%	-54.0%	+271.8%
EDITEditas Medicine, Inc.	$298M	+11.8%	+48.3%	+97.4%	—	-68.9%	-91.2%	-90.5%
NTLAIntellia Therapeutics, Inc.	$1.5B	+0.1%	+44.5%	+57.7%	—	-69.7%	-81.3%	-39.8%
SGMOSangamo Therapeutics, Inc.	$38M	-36.3%	-59.6%	-75.3%	—	-86.7%	-98.3%	-96.9%

Compare:SRPT vs BMRN SRPT vs ALNY SRPT vs RARE SRPT vs BMRN vs ALNY

About SRPT Dividend Returns

Sarepta Therapeutics, Inc. (SRPT) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of SRPT over the past year?

Sarepta Therapeutics, Inc. (SRPT) delivered a return of -65.77% over the past year. Since SRPT does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in SRPT be worth today?

A $10,000 investment in Sarepta Therapeutics, Inc. one year ago would be worth $3,423 today, representing a loss of $6,577.

Q3Does SRPT pay dividends?

Sarepta Therapeutics, Inc. (SRPT) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For SRPT, the total return equals the price-only return.

Q4Did SRPT beat the S&P 500?

No, Sarepta Therapeutics, Inc. (SRPT) underperformed the S&P 500 by 94.21 percentage points over the past year. SRPT delivered a total return of -65.77%, compared to the S&P 500's 28.44%. This means a passive S&P 500 index fund outperformed SRPT by 94.21pp during this period.

Q5What is SRPT's worst drawdown?

Sarepta Therapeutics, Inc. (SRPT) experienced a maximum drawdown of -81.26% over the past year, declining from its peak on 2025-05-05 to its trough on 2025-07-25. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is SRPT's long-term total return over 10, 20, or 30 years?

Here are Sarepta Therapeutics, Inc. (SRPT)'s long-term returns with dividends reinvested. Over 10 years, the total return is 30.0% (2.7% CAGR) — $10,000 would have grown to $13,001. Over 20 years: -41.6% total return (-2.7% CAGR) — $10,000 → $5,839. Over 30 years: -44.1% total return (-1.9% CAGR) — $10,000 → $5,587. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was SRPT's best and worst year?

Sarepta Therapeutics, Inc.'s best calendar year was 2012 with a total return of 481.1%. Its worst year was 2025 with a total return of -82.7%. This range shows the volatility investors should expect — the difference between the best and worst year is 563.7 percentage points.