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Stock Comparison

CBUS vs OFIX vs NVCR vs PGEN vs FATE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CBUS
Cibus, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$686M
5Y Perf.-99.3%
OFIX
Orthofix Medical Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$488M
5Y Perf.-64.6%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-75.0%
PGEN
Precigen, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.22B
5Y Perf.+88.6%
FATE
Fate Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$280M
5Y Perf.-92.5%

CBUS vs OFIX vs NVCR vs PGEN vs FATE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CBUS logoCBUS
OFIX logoOFIX
NVCR logoNVCR
PGEN logoPGEN
FATE logoFATE
IndustryBiotechnologyMedical - DevicesMedical - Instruments & SuppliesBiotechnologyBiotechnology
Market Cap$686M$488M$1.92B$1.22B$280M
Revenue (TTM)$4M$825M$674M$6M$7M
Net Income (TTM)$-127M$-60M$-173M$-247M$-136M
Gross Margin23.9%69.0%75.2%23.0%
Operating Margin-26.8%-4.0%-27.2%-18.6%-22.2%
Total Debt$33M$229M$290M$6M$78M
Cash & Equiv.$10M$82M$103M$30M$47M

CBUS vs OFIX vs NVCR vs PGEN vs FATELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CBUS
OFIX
NVCR
PGEN
FATE
StockMay 20May 26Return
Cibus, Inc. (CBUS)1000.7-99.3%
Orthofix Medical In… (OFIX)10035.4-64.6%
NovoCure Limited (NVCR)10025.0-75.0%
Precigen, Inc. (PGEN)100188.6+88.6%
Fate Therapeutics, … (FATE)1007.5-92.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: CBUS vs OFIX vs NVCR vs PGEN vs FATE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: OFIX leads in 3 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. NovoCure Limited is the stronger pick specifically for growth and revenue expansion. PGEN also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
CBUS
Cibus, Inc.
The Growth Play

CBUS is the clearest fit if your priority is growth exposure.

  • Rev growth -14.6%, EPS growth 74.3%, 3Y rev CAGR 185.1%
Best for: growth exposure
OFIX
Orthofix Medical Inc.
The Income Pick

OFIX carries the broadest edge in this set and is the clearest fit for income & stability.

  • beta 1.21
  • -7.3% margin vs PGEN's -39.1%
  • Beta 1.21 vs CBUS's 3.12, lower leverage
  • -7.0% ROA vs PGEN's -144.1%, ROIC -8.6% vs -152.8%
Best for: income & stability
NVCR
NovoCure Limited
The Growth Leader

NVCR is the #2 pick in this set and the best alternative if growth is your priority.

  • 8.3% revenue growth vs FATE's -51.2%
Best for: growth
PGEN
Precigen, Inc.
The Defensive Pick

PGEN ranks third and is worth considering specifically for sleep-well-at-night and defensive.

  • Lower volatility, beta 1.44, Low D/E 14.3%, current ratio 4.76x
  • Beta 1.44, current ratio 4.76x
  • +207.4% vs CBUS's -40.0%
Best for: sleep-well-at-night and defensive
FATE
Fate Therapeutics, Inc.
The Long-Run Compounder

FATE is the clearest fit if your priority is long-term compounding.

  • 40.5% 10Y total return vs NVCR's 30.3%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthNVCR logoNVCR8.3% revenue growth vs FATE's -51.2%
Quality / MarginsOFIX logoOFIX-7.3% margin vs PGEN's -39.1%
Stability / SafetyOFIX logoOFIXBeta 1.21 vs CBUS's 3.12, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)PGEN logoPGEN+207.4% vs CBUS's -40.0%
Efficiency (ROA)OFIX logoOFIX-7.0% ROA vs PGEN's -144.1%, ROIC -8.6% vs -152.8%

CBUS vs OFIX vs NVCR vs PGEN vs FATE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CBUSCibus, Inc.
FY 2025
Reportable Segment
100.0%$4M
OFIXOrthofix Medical Inc.
FY 2025
Global Spine
100.0%$688M
NVCRNovoCure Limited

Segment breakdown not available.

PGENPrecigen, Inc.
FY 2024
Exemplar Segment
100.0%$4M
FATEFate Therapeutics, Inc.
FY 2023
Upfront Fee And Equity Premium
100.0%$31M

CBUS vs OFIX vs NVCR vs PGEN vs FATE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLOFIXLAGGINGFATE

Income & Cash Flow (Last 12 Months)

OFIX leads this category, winning 4 of 6 comparable metrics.

OFIX is the larger business by revenue, generating $825M annually — 226.8x CBUS's $4M. OFIX is the more profitable business, keeping -7.3% of every revenue dollar as net income compared to PGEN's -39.1%. On growth, PGEN holds the edge at +2.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCBUS logoCBUSCibus, Inc.OFIX logoOFIXOrthofix Medical …NVCR logoNVCRNovoCure LimitedPGEN logoPGENPrecigen, Inc.FATE logoFATEFate Therapeutics…
RevenueTrailing 12 months$4M$825M$674M$6M$7M
EBITDAEarnings before interest/tax-$92M$102M-$165M-$115M-$148M
Net IncomeAfter-tax profit-$127M-$60M-$173M-$247M-$136M
Free Cash FlowCash after capex-$51M-$4M-$48M-$76M-$88M
Gross MarginGross profit ÷ Revenue+23.9%+69.0%+75.2%+23.0%
Operating MarginEBIT ÷ Revenue-26.8%-4.0%-27.2%-18.6%-22.2%
Net MarginNet income ÷ Revenue-34.9%-7.3%-25.7%-39.1%-20.5%
FCF MarginFCF ÷ Revenue-14.1%-0.4%-7.1%-12.0%-13.2%
Rev. Growth (YoY)Latest quarter vs prior year-12.8%+1.6%+12.3%+2.1%-26.4%
EPS Growth (YoY)Latest quarter vs prior year+55.2%+61.5%-100.0%-11.7%+38.6%
OFIX leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

OFIX leads this category, winning 2 of 3 comparable metrics.
MetricCBUS logoCBUSCibus, Inc.OFIX logoOFIXOrthofix Medical …NVCR logoNVCRNovoCure LimitedPGEN logoPGENPrecigen, Inc.FATE logoFATEFate Therapeutics…
Market CapShares × price$686M$488M$1.9B$1.2B$280M
Enterprise ValueMkt cap + debt − cash$709M$635M$2.1B$1.2B$312M
Trailing P/EPrice ÷ TTM EPS-0.54x-5.29x-13.80x-8.83x-2.11x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue188.61x0.59x2.92x309.66x42.18x
Price / BookPrice ÷ Book value/share31.44x1.07x5.51x28.85x1.39x
Price / FCFMarket cap ÷ FCF
OFIX leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

OFIX leads this category, winning 4 of 9 comparable metrics.

OFIX delivers a -13.4% return on equity — every $100 of shareholder capital generates $-13 in annual profit, vs $-6 for PGEN. PGEN carries lower financial leverage with a 0.14x debt-to-equity ratio, signaling a more conservative balance sheet compared to CBUS's 1.51x. On the Piotroski fundamental quality scale (0–9), NVCR scores 5/9 vs FATE's 2/9, reflecting solid financial health.

MetricCBUS logoCBUSCibus, Inc.OFIX logoOFIXOrthofix Medical …NVCR logoNVCRNovoCure LimitedPGEN logoPGENPrecigen, Inc.FATE logoFATEFate Therapeutics…
ROE (TTM)Return on equity-2.3%-13.4%-50.8%-5.9%-65.8%
ROA (TTM)Return on assets-38.6%-7.0%-16.5%-144.1%-42.7%
ROICReturn on invested capital-61.5%-8.6%-16.4%-152.8%-36.5%
ROCEReturn on capital employed-21.8%-9.7%-28.9%-107.2%-43.1%
Piotroski ScoreFundamental quality 0–924532
Debt / EquityFinancial leverage1.51x0.51x0.85x0.14x0.38x
Net DebtTotal debt minus cash$23M$147M$187M-$24M$31M
Cash & Equiv.Liquid assets$10M$82M$103M$30M$47M
Total DebtShort + long-term debt$33M$229M$290M$6M$78M
Interest CoverageEBIT ÷ Interest expense-2.49x-4.97x-96.80x-273.83x
OFIX leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

PGEN leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in PGEN five years ago would be worth $6,346 today (with dividends reinvested), compared to $69 for CBUS. Over the past 12 months, PGEN leads with a +207.4% total return vs CBUS's -40.0%. The 3-year compound annual growth rate (CAGR) favors PGEN at 49.2% vs CBUS's -54.4% — a key indicator of consistent wealth creation.

MetricCBUS logoCBUSCibus, Inc.OFIX logoOFIXOrthofix Medical …NVCR logoNVCRNovoCure LimitedPGEN logoPGENPrecigen, Inc.FATE logoFATEFate Therapeutics…
YTD ReturnYear-to-date-20.2%-18.7%+28.3%-3.0%+145.5%
1-Year ReturnPast 12 months-40.0%+0.4%+1.1%+207.4%+143.0%
3-Year ReturnCumulative with dividends-90.5%-35.1%-75.7%+232.0%-55.4%
5-Year ReturnCumulative with dividends-99.3%-72.7%-91.3%-36.5%-96.8%
10-Year ReturnCumulative with dividends-99.7%-72.0%+30.3%-84.6%+40.5%
CAGR (3Y)Annualised 3-year return-54.4%-13.4%-37.6%+49.2%-23.6%
PGEN leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — OFIX and FATE each lead in 1 of 2 comparable metrics.

OFIX is the less volatile stock with a 1.21 beta — it tends to amplify market swings less than CBUS's 3.12 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. FATE currently trades 98.6% from its 52-week high vs CBUS's 35.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCBUS logoCBUSCibus, Inc.OFIX logoOFIXOrthofix Medical …NVCR logoNVCRNovoCure LimitedPGEN logoPGENPrecigen, Inc.FATE logoFATEFate Therapeutics…
Beta (5Y)Sensitivity to S&P 5003.12x1.21x2.20x1.44x2.17x
52-Week HighHighest price in past year$4.19$16.99$20.06$5.23$2.46
52-Week LowLowest price in past year$1.09$10.24$9.82$1.23$0.91
% of 52W HighCurrent price vs 52-week peak+35.8%+71.0%+83.9%+79.3%+98.6%
RSI (14)Momentum oscillator 0–10045.850.469.862.781.0
Avg Volume (50D)Average daily shares traded603K274K1.5M4.3M1.9M
Evenly matched — OFIX and FATE each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: CBUS as "Buy", OFIX as "Hold", NVCR as "Buy", PGEN as "Buy", FATE as "Buy". Consensus price targets imply 1525.5% upside for FATE (target: $40) vs 44.6% for PGEN (target: $6).

MetricCBUS logoCBUSCibus, Inc.OFIX logoOFIXOrthofix Medical …NVCR logoNVCRNovoCure LimitedPGEN logoPGENPrecigen, Inc.FATE logoFATEFate Therapeutics…
Analyst RatingConsensus buy/hold/sellBuyHoldBuyBuyBuy
Price TargetConsensus 12-month target$11.50$18.00$33.50$6.00$39.50
# AnalystsCovering analysts417151631
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

OFIX leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). PGEN leads in 1 (Total Returns). 1 tied.

Best OverallOrthofix Medical Inc. (OFIX)Leads 3 of 6 categories
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CBUS vs OFIX vs NVCR vs PGEN vs FATE: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is CBUS or OFIX or NVCR or PGEN or FATE a better buy right now?

For growth investors, NovoCure Limited (NVCR) is the stronger pick with 8.

3% revenue growth year-over-year, versus -51. 2% for Fate Therapeutics, Inc. (FATE). Analysts rate Cibus, Inc. (CBUS) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CBUS or OFIX or NVCR or PGEN or FATE?

Over the past 5 years, Precigen, Inc.

(PGEN) delivered a total return of -36. 5%, compared to -99. 3% for Cibus, Inc. (CBUS). Over 10 years, the gap is even starker: FATE returned +40. 5% versus CBUS's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CBUS or OFIX or NVCR or PGEN or FATE?

By beta (market sensitivity over 5 years), Orthofix Medical Inc.

(OFIX) is the lower-risk stock at 1. 21β versus Cibus, Inc. 's 3. 12β — meaning CBUS is approximately 157% more volatile than OFIX relative to the S&P 500. On balance sheet safety, Precigen, Inc. (PGEN) carries a lower debt/equity ratio of 14% versus 151% for Cibus, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CBUS or OFIX or NVCR or PGEN or FATE?

By revenue growth (latest reported year), NovoCure Limited (NVCR) is pulling ahead at 8.

3% versus -51. 2% for Fate Therapeutics, Inc. (FATE). On earnings-per-share growth, the picture is similar: Cibus, Inc. grew EPS 74. 3% year-over-year, compared to -20. 5% for Precigen, Inc.. Over a 3-year CAGR, CBUS leads at 185. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CBUS or OFIX or NVCR or PGEN or FATE?

Orthofix Medical Inc.

(OFIX) is the more profitable company, earning -11. 2% net margin versus -34. 9% for Cibus, Inc. — meaning it keeps -11. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: OFIX leads at -8. 3% versus -34. 4% for PGEN. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — CBUS or OFIX or NVCR or PGEN or FATE?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is CBUS or OFIX or NVCR or PGEN or FATE better for a retirement portfolio?

For long-horizon retirement investors, Orthofix Medical Inc.

(OFIX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 21)). Cibus, Inc. (CBUS) carries a higher beta of 3. 12 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (OFIX: -72. 0%, CBUS: -99. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between CBUS and OFIX and NVCR and PGEN and FATE?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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CBUS

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 14%
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OFIX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 41%
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NVCR

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 45%
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PGEN

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 103%
  • Gross Margin > 13%
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FATE

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
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Beat Both

Find stocks that outperform CBUS and OFIX and NVCR and PGEN and FATE on the metrics below

Revenue Growth>
%
(CBUS: -12.8% · OFIX: 1.6%)

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