Biotechnology
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CDTX vs AGIO vs IMVT vs JAZZ
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
CDTX vs AGIO vs IMVT vs JAZZ — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $6.96B | $1.60B | $5.83B | $14.34B |
| Revenue (TTM) | $0.00 | $66M | $0.00 | $4.44B |
| Net Income (TTM) | $-185M | $-423M | $-464M | $29M |
| Gross Margin | 100.0% | 82.1% | — | 66.9% |
| Operating Margin | -138.1% | -7.2% | — | 13.9% |
| Forward P/E | — | — | — | 9.5x |
| Total Debt | $4M | $62M | $98K | $5.42B |
| Cash & Equiv. | $190M | $89M | $714M | $1.39B |
CDTX vs AGIO vs IMVT vs JAZZ — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | Jan 26 | Return |
|---|---|---|---|
| Cidara Therapeutics… (CDTX) | 100 | 305.8 | +205.8% |
| Agios Pharmaceutica… (AGIO) | 100 | 52.6 | -47.4% |
| Immunovant, Inc. (IMVT) | 100 | 99.1 | -0.9% |
| Jazz Pharmaceutical… (JAZZ) | 100 | 142.5 | +42.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CDTX vs AGIO vs IMVT vs JAZZ
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CDTX is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 0.87, Low D/E 2.2%, current ratio 4.25x
- +10.2% vs AGIO's -4.7%
AGIO is the clearest fit if your priority is growth exposure and defensive.
- Rev growth 48.0%, EPS growth -161.2%, 3Y rev CAGR 56.0%
- Beta 1.12, current ratio 11.46x
- 48.0% revenue growth vs CDTX's -94.5%
IMVT is the clearest fit if your priority is long-term compounding.
- 188.1% 10Y total return vs CDTX's -14.7%
- 3.2% margin vs CDTX's -133.2%
JAZZ carries the broadest edge in this set and is the clearest fit for income & stability.
- beta 0.65
- Beta 0.65 vs IMVT's 1.37
- 0.3% ROA vs IMVT's -44.1%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 48.0% revenue growth vs CDTX's -94.5% | |
| Quality / Margins | 3.2% margin vs CDTX's -133.2% | |
| Stability / Safety | Beta 0.65 vs IMVT's 1.37 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +10.2% vs AGIO's -4.7% | |
| Efficiency (ROA) | 0.3% ROA vs IMVT's -44.1% |
CDTX vs AGIO vs IMVT vs JAZZ — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
CDTX vs AGIO vs IMVT vs JAZZ — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
JAZZ leads in 3 of 6 categories
CDTX leads 1 • AGIO leads 0 • IMVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
JAZZ leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JAZZ and IMVT operate at a comparable scale, with $4.4B and $0 in trailing revenue. JAZZ is the more profitable business, keeping 0.7% of every revenue dollar as net income compared to CDTX's -133.2%. On growth, AGIO holds the edge at +137.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $66M | $0 | $4.4B |
| EBITDAEarnings before interest/tax | -$195M | -$470M | -$487M | $994M |
| Net IncomeAfter-tax profit | -$185M | -$423M | -$464M | $29M |
| Free Cash FlowCash after capex | -$133M | -$385M | -$423M | $1.2B |
| Gross MarginGross profit ÷ Revenue | +100.0% | +82.1% | — | +66.9% |
| Operating MarginEBIT ÷ Revenue | -138.1% | -7.2% | — | +13.9% |
| Net MarginNet income ÷ Revenue | -133.2% | -6.4% | — | +0.7% |
| FCF MarginFCF ÷ Revenue | -138.6% | -5.8% | — | +28.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +137.7% | — | +19.1% |
| EPS Growth (YoY)Latest quarter vs prior year | -30.3% | -9.0% | +19.7% | +3.9% |
Valuation Metrics
JAZZ leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $7.0B | $1.6B | $5.8B | $14.3B |
| Enterprise ValueMkt cap + debt − cash | $6.8B | $1.6B | $5.1B | $18.4B |
| Trailing P/EPrice ÷ TTM EPS | -8.28x | -3.79x | -10.50x | -39.14x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 9.45x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 23.97x |
| Price / SalesMarket cap ÷ Revenue | 5460.07x | 29.70x | — | 3.36x |
| Price / BookPrice ÷ Book value/share | 8.61x | 1.31x | 6.14x | 3.23x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 11.06x |
Profitability & Efficiency
JAZZ leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
JAZZ delivers a 0.7% return on equity — every $100 of shareholder capital generates $1 in annual profit, vs $-47 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JAZZ's 1.26x. On the Piotroski fundamental quality scale (0–9), JAZZ scores 5/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -43.7% | -34.1% | -47.1% | +0.7% |
| ROA (TTM)Return on assets | -35.6% | -31.7% | -44.1% | +0.3% |
| ROICReturn on invested capital | — | -26.3% | — | +2.1% |
| ROCEReturn on capital employed | -2.1% | -33.8% | -66.1% | +2.2% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 | 2 | 5 |
| Debt / EquityFinancial leverage | 0.02x | 0.05x | 0.00x | 1.26x |
| Net DebtTotal debt minus cash | -$186M | -$27M | -$714M | $4.0B |
| Cash & Equiv.Liquid assets | $190M | $89M | $714M | $1.4B |
| Total DebtShort + long-term debt | $4M | $62M | $98,000 | $5.4B |
| Interest CoverageEBIT ÷ Interest expense | — | — | — | -3.72x |
Total Returns (Dividends Reinvested)
CDTX leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CDTX five years ago would be worth $54,797 today (with dividends reinvested), compared to $4,897 for AGIO. Over the past 12 months, CDTX leads with a +1023.8% total return vs AGIO's -4.7%. The 3-year compound annual growth rate (CAGR) favors CDTX at 118.6% vs AGIO's 2.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +0.2% | -0.7% | +10.7% | +32.0% |
| 1-Year ReturnPast 12 months | +1023.8% | -4.7% | +107.2% | +105.6% |
| 3-Year ReturnCumulative with dividends | +944.2% | +6.2% | +48.4% | +64.8% |
| 5-Year ReturnCumulative with dividends | +448.0% | -51.0% | +73.9% | +32.2% |
| 10-Year ReturnCumulative with dividends | -14.7% | -38.1% | +188.1% | +58.3% |
| CAGR (3Y)Annualised 3-year return | +118.6% | +2.0% | +14.1% | +18.1% |
Risk & Volatility
Evenly matched — CDTX and JAZZ each lead in 1 of 2 comparable metrics.
Risk & Volatility
JAZZ is the less volatile stock with a 0.65 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CDTX currently trades 100.0% from its 52-week high vs AGIO's 58.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.87x | 1.12x | 1.37x | 0.65x |
| 52-Week HighHighest price in past year | $221.42 | $46.00 | $30.09 | $230.40 |
| 52-Week LowLowest price in past year | $18.51 | $22.24 | $13.36 | $97.50 |
| % of 52W HighCurrent price vs 52-week peak | +100.0% | +58.7% | +95.3% | +99.2% |
| RSI (14)Momentum oscillator 0–100 | 84.8 | 42.7 | 55.7 | 67.7 |
| Avg Volume (50D)Average daily shares traded | 0 | 1.0M | 1.4M | 956K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: CDTX as "Buy", AGIO as "Buy", IMVT as "Buy", JAZZ as "Buy". Consensus price targets imply 58.7% upside for IMVT (target: $46) vs -5.4% for JAZZ (target: $216).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $221.50 | $37.75 | $45.50 | $216.14 |
| # AnalystsCovering analysts | 11 | 29 | 23 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.9% |
JAZZ leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CDTX leads in 1 (Total Returns). 1 tied.
CDTX vs AGIO vs IMVT vs JAZZ: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is CDTX or AGIO or IMVT or JAZZ a better buy right now?
For growth investors, Agios Pharmaceuticals, Inc.
(AGIO) is the stronger pick with 48. 0% revenue growth year-over-year, versus -94. 5% for Cidara Therapeutics, Inc. (CDTX). Analysts rate Cidara Therapeutics, Inc. (CDTX) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CDTX or AGIO or IMVT or JAZZ?
Over the past 5 years, Cidara Therapeutics, Inc.
(CDTX) delivered a total return of +448. 0%, compared to -51. 0% for Agios Pharmaceuticals, Inc. (AGIO). Over 10 years, the gap is even starker: IMVT returned +188. 1% versus AGIO's -38. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CDTX or AGIO or IMVT or JAZZ?
By beta (market sensitivity over 5 years), Jazz Pharmaceuticals plc (JAZZ) is the lower-risk stock at 0.
65β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately 112% more volatile than JAZZ relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 126% for Jazz Pharmaceuticals plc — giving it more financial flexibility in a downturn.
04Which is growing faster — CDTX or AGIO or IMVT or JAZZ?
By revenue growth (latest reported year), Agios Pharmaceuticals, Inc.
(AGIO) is pulling ahead at 48. 0% versus -94. 5% for Cidara Therapeutics, Inc. (CDTX). On earnings-per-share growth, the picture is similar: Immunovant, Inc. grew EPS -45. 2% year-over-year, compared to -409. 5% for Cidara Therapeutics, Inc.. Over a 3-year CAGR, AGIO leads at 56. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CDTX or AGIO or IMVT or JAZZ?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -133. 2% for Cidara Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JAZZ leads at 5. 3% versus -138. 1% for CDTX. At the gross margin level — before operating expenses — CDTX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is CDTX or AGIO or IMVT or JAZZ more undervalued right now?
Analyst consensus price targets imply the most upside for IMVT: 58.
7% to $45. 50.
07Which pays a better dividend — CDTX or AGIO or IMVT or JAZZ?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is CDTX or AGIO or IMVT or JAZZ better for a retirement portfolio?
For long-horizon retirement investors, Jazz Pharmaceuticals plc (JAZZ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
65)). Both have compounded well over 10 years (JAZZ: +58. 3%, IMVT: +188. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between CDTX and AGIO and IMVT and JAZZ?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CDTX is a small-cap quality compounder stock; AGIO is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; JAZZ is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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