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Stock Comparison

CDTX vs AGIO vs IMVT vs JAZZ

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CDTX
Cidara Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.96B
5Y Perf.+205.8%
AGIO
Agios Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.60B
5Y Perf.-47.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.83B
5Y Perf.-0.9%
JAZZ
Jazz Pharmaceuticals plc

Biotechnology

HealthcareNASDAQ • IE
Market Cap$14.34B
5Y Perf.+42.5%

CDTX vs AGIO vs IMVT vs JAZZ — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CDTX logoCDTX
AGIO logoAGIO
IMVT logoIMVT
JAZZ logoJAZZ
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$6.96B$1.60B$5.83B$14.34B
Revenue (TTM)$0.00$66M$0.00$4.44B
Net Income (TTM)$-185M$-423M$-464M$29M
Gross Margin100.0%82.1%66.9%
Operating Margin-138.1%-7.2%13.9%
Forward P/E9.5x
Total Debt$4M$62M$98K$5.42B
Cash & Equiv.$190M$89M$714M$1.39B

CDTX vs AGIO vs IMVT vs JAZZLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CDTX
AGIO
IMVT
JAZZ
StockMay 20Jan 26Return
Cidara Therapeutics… (CDTX)100305.8+205.8%
Agios Pharmaceutica… (AGIO)10052.6-47.4%
Immunovant, Inc. (IMVT)10099.1-0.9%
Jazz Pharmaceutical… (JAZZ)100142.5+42.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: CDTX vs AGIO vs IMVT vs JAZZ

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JAZZ leads in 2 of 6 categories, making it the strongest pick for capital preservation and lower volatility and operational efficiency and capital deployment. Cidara Therapeutics, Inc. is the stronger pick specifically for recent price momentum and sentiment. AGIO and IMVT also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
CDTX
Cidara Therapeutics, Inc.
The Defensive Pick

CDTX is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.

  • Lower volatility, beta 0.87, Low D/E 2.2%, current ratio 4.25x
  • +10.2% vs AGIO's -4.7%
Best for: sleep-well-at-night
AGIO
Agios Pharmaceuticals, Inc.
The Growth Play

AGIO is the clearest fit if your priority is growth exposure and defensive.

  • Rev growth 48.0%, EPS growth -161.2%, 3Y rev CAGR 56.0%
  • Beta 1.12, current ratio 11.46x
  • 48.0% revenue growth vs CDTX's -94.5%
Best for: growth exposure and defensive
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding.

  • 188.1% 10Y total return vs CDTX's -14.7%
  • 3.2% margin vs CDTX's -133.2%
Best for: long-term compounding
JAZZ
Jazz Pharmaceuticals plc
The Income Pick

JAZZ carries the broadest edge in this set and is the clearest fit for income & stability.

  • beta 0.65
  • Beta 0.65 vs IMVT's 1.37
  • 0.3% ROA vs IMVT's -44.1%
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthAGIO logoAGIO48.0% revenue growth vs CDTX's -94.5%
Quality / MarginsIMVT logoIMVT3.2% margin vs CDTX's -133.2%
Stability / SafetyJAZZ logoJAZZBeta 0.65 vs IMVT's 1.37
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)CDTX logoCDTX+10.2% vs AGIO's -4.7%
Efficiency (ROA)JAZZ logoJAZZ0.3% ROA vs IMVT's -44.1%

CDTX vs AGIO vs IMVT vs JAZZ — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CDTXCidara Therapeutics, Inc.
FY 2024
Reportable Segment
100.0%$1M
AGIOAgios Pharmaceuticals, Inc.
FY 2025
Product
100.0%$54M
IMVTImmunovant, Inc.

Segment breakdown not available.

JAZZJazz Pharmaceuticals plc
FY 2025
Xywav
39.6%$1.7B
Epidiolex/Epidyolex
25.3%$1.1B
Rylaze/Enrylaze
9.6%$403M
Zepzelca
7.3%$307M
High Sodium AG Oxybate Product Royalty Revenue
5.1%$212M
Defitelio/Defibrotide
4.8%$199M
Vyxeos
3.5%$147M
Other (4)
4.8%$201M

CDTX vs AGIO vs IMVT vs JAZZ — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJAZZLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

JAZZ leads this category, winning 4 of 6 comparable metrics.

JAZZ and IMVT operate at a comparable scale, with $4.4B and $0 in trailing revenue. JAZZ is the more profitable business, keeping 0.7% of every revenue dollar as net income compared to CDTX's -133.2%. On growth, AGIO holds the edge at +137.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCDTX logoCDTXCidara Therapeuti…AGIO logoAGIOAgios Pharmaceuti…IMVT logoIMVTImmunovant, Inc.JAZZ logoJAZZJazz Pharmaceutic…
RevenueTrailing 12 months$0$66M$0$4.4B
EBITDAEarnings before interest/tax-$195M-$470M-$487M$994M
Net IncomeAfter-tax profit-$185M-$423M-$464M$29M
Free Cash FlowCash after capex-$133M-$385M-$423M$1.2B
Gross MarginGross profit ÷ Revenue+100.0%+82.1%+66.9%
Operating MarginEBIT ÷ Revenue-138.1%-7.2%+13.9%
Net MarginNet income ÷ Revenue-133.2%-6.4%+0.7%
FCF MarginFCF ÷ Revenue-138.6%-5.8%+28.1%
Rev. Growth (YoY)Latest quarter vs prior year+137.7%+19.1%
EPS Growth (YoY)Latest quarter vs prior year-30.3%-9.0%+19.7%+3.9%
JAZZ leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

JAZZ leads this category, winning 2 of 3 comparable metrics.
MetricCDTX logoCDTXCidara Therapeuti…AGIO logoAGIOAgios Pharmaceuti…IMVT logoIMVTImmunovant, Inc.JAZZ logoJAZZJazz Pharmaceutic…
Market CapShares × price$7.0B$1.6B$5.8B$14.3B
Enterprise ValueMkt cap + debt − cash$6.8B$1.6B$5.1B$18.4B
Trailing P/EPrice ÷ TTM EPS-8.28x-3.79x-10.50x-39.14x
Forward P/EPrice ÷ next-FY EPS est.9.45x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple23.97x
Price / SalesMarket cap ÷ Revenue5460.07x29.70x3.36x
Price / BookPrice ÷ Book value/share8.61x1.31x6.14x3.23x
Price / FCFMarket cap ÷ FCF11.06x
JAZZ leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

JAZZ leads this category, winning 5 of 8 comparable metrics.

JAZZ delivers a 0.7% return on equity — every $100 of shareholder capital generates $1 in annual profit, vs $-47 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JAZZ's 1.26x. On the Piotroski fundamental quality scale (0–9), JAZZ scores 5/9 vs IMVT's 2/9, reflecting solid financial health.

MetricCDTX logoCDTXCidara Therapeuti…AGIO logoAGIOAgios Pharmaceuti…IMVT logoIMVTImmunovant, Inc.JAZZ logoJAZZJazz Pharmaceutic…
ROE (TTM)Return on equity-43.7%-34.1%-47.1%+0.7%
ROA (TTM)Return on assets-35.6%-31.7%-44.1%+0.3%
ROICReturn on invested capital-26.3%+2.1%
ROCEReturn on capital employed-2.1%-33.8%-66.1%+2.2%
Piotroski ScoreFundamental quality 0–93225
Debt / EquityFinancial leverage0.02x0.05x0.00x1.26x
Net DebtTotal debt minus cash-$186M-$27M-$714M$4.0B
Cash & Equiv.Liquid assets$190M$89M$714M$1.4B
Total DebtShort + long-term debt$4M$62M$98,000$5.4B
Interest CoverageEBIT ÷ Interest expense-3.72x
JAZZ leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

CDTX leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in CDTX five years ago would be worth $54,797 today (with dividends reinvested), compared to $4,897 for AGIO. Over the past 12 months, CDTX leads with a +1023.8% total return vs AGIO's -4.7%. The 3-year compound annual growth rate (CAGR) favors CDTX at 118.6% vs AGIO's 2.0% — a key indicator of consistent wealth creation.

MetricCDTX logoCDTXCidara Therapeuti…AGIO logoAGIOAgios Pharmaceuti…IMVT logoIMVTImmunovant, Inc.JAZZ logoJAZZJazz Pharmaceutic…
YTD ReturnYear-to-date+0.2%-0.7%+10.7%+32.0%
1-Year ReturnPast 12 months+1023.8%-4.7%+107.2%+105.6%
3-Year ReturnCumulative with dividends+944.2%+6.2%+48.4%+64.8%
5-Year ReturnCumulative with dividends+448.0%-51.0%+73.9%+32.2%
10-Year ReturnCumulative with dividends-14.7%-38.1%+188.1%+58.3%
CAGR (3Y)Annualised 3-year return+118.6%+2.0%+14.1%+18.1%
CDTX leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — CDTX and JAZZ each lead in 1 of 2 comparable metrics.

JAZZ is the less volatile stock with a 0.65 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CDTX currently trades 100.0% from its 52-week high vs AGIO's 58.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCDTX logoCDTXCidara Therapeuti…AGIO logoAGIOAgios Pharmaceuti…IMVT logoIMVTImmunovant, Inc.JAZZ logoJAZZJazz Pharmaceutic…
Beta (5Y)Sensitivity to S&P 5000.87x1.12x1.37x0.65x
52-Week HighHighest price in past year$221.42$46.00$30.09$230.40
52-Week LowLowest price in past year$18.51$22.24$13.36$97.50
% of 52W HighCurrent price vs 52-week peak+100.0%+58.7%+95.3%+99.2%
RSI (14)Momentum oscillator 0–10084.842.755.767.7
Avg Volume (50D)Average daily shares traded01.0M1.4M956K
Evenly matched — CDTX and JAZZ each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: CDTX as "Buy", AGIO as "Buy", IMVT as "Buy", JAZZ as "Buy". Consensus price targets imply 58.7% upside for IMVT (target: $46) vs -5.4% for JAZZ (target: $216).

MetricCDTX logoCDTXCidara Therapeuti…AGIO logoAGIOAgios Pharmaceuti…IMVT logoIMVTImmunovant, Inc.JAZZ logoJAZZJazz Pharmaceutic…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$221.50$37.75$45.50$216.14
# AnalystsCovering analysts11292348
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+0.9%
Insufficient data to determine a leader in this category.
Key Takeaway

JAZZ leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CDTX leads in 1 (Total Returns). 1 tied.

Best OverallJazz Pharmaceuticals plc (JAZZ)Leads 3 of 6 categories
Loading custom metrics...

CDTX vs AGIO vs IMVT vs JAZZ: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is CDTX or AGIO or IMVT or JAZZ a better buy right now?

For growth investors, Agios Pharmaceuticals, Inc.

(AGIO) is the stronger pick with 48. 0% revenue growth year-over-year, versus -94. 5% for Cidara Therapeutics, Inc. (CDTX). Analysts rate Cidara Therapeutics, Inc. (CDTX) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CDTX or AGIO or IMVT or JAZZ?

Over the past 5 years, Cidara Therapeutics, Inc.

(CDTX) delivered a total return of +448. 0%, compared to -51. 0% for Agios Pharmaceuticals, Inc. (AGIO). Over 10 years, the gap is even starker: IMVT returned +188. 1% versus AGIO's -38. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CDTX or AGIO or IMVT or JAZZ?

By beta (market sensitivity over 5 years), Jazz Pharmaceuticals plc (JAZZ) is the lower-risk stock at 0.

65β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately 112% more volatile than JAZZ relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 126% for Jazz Pharmaceuticals plc — giving it more financial flexibility in a downturn.

04

Which is growing faster — CDTX or AGIO or IMVT or JAZZ?

By revenue growth (latest reported year), Agios Pharmaceuticals, Inc.

(AGIO) is pulling ahead at 48. 0% versus -94. 5% for Cidara Therapeutics, Inc. (CDTX). On earnings-per-share growth, the picture is similar: Immunovant, Inc. grew EPS -45. 2% year-over-year, compared to -409. 5% for Cidara Therapeutics, Inc.. Over a 3-year CAGR, AGIO leads at 56. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CDTX or AGIO or IMVT or JAZZ?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -133. 2% for Cidara Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JAZZ leads at 5. 3% versus -138. 1% for CDTX. At the gross margin level — before operating expenses — CDTX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CDTX or AGIO or IMVT or JAZZ more undervalued right now?

Analyst consensus price targets imply the most upside for IMVT: 58.

7% to $45. 50.

07

Which pays a better dividend — CDTX or AGIO or IMVT or JAZZ?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is CDTX or AGIO or IMVT or JAZZ better for a retirement portfolio?

For long-horizon retirement investors, Jazz Pharmaceuticals plc (JAZZ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

65)). Both have compounded well over 10 years (JAZZ: +58. 3%, IMVT: +188. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CDTX and AGIO and IMVT and JAZZ?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CDTX is a small-cap quality compounder stock; AGIO is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; JAZZ is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.

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CDTX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 60%
Run This Screen
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AGIO

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 68%
  • Gross Margin > 49%
Run This Screen
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IMVT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
Run This Screen
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JAZZ

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
  • Gross Margin > 40%
Run This Screen
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Beat Both

Find stocks that outperform CDTX and AGIO and IMVT and JAZZ on the metrics below

Revenue Growth>
%
(CDTX: -94.5% · AGIO: 137.7%)

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