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CGEN vs ABSI vs RXRX vs SDGR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Healthcare Information Services
CGEN vs ABSI vs RXRX vs SDGR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Medical - Healthcare Information Services |
| Market Cap | $260M | $917M | $1.48B | $981M |
| Revenue (TTM) | $5M | $2M | $66M | $255M |
| Net Income (TTM) | $-31M | $-118M | $-560M | $-103M |
| Gross Margin | -5.2% | -13.4% | -34.4% | 55.3% |
| Operating Margin | -6.5% | -60.3% | -8.8% | -64.7% |
| Total Debt | $3M | $5M | $78M | $109M |
| Cash & Equiv. | $18M | $20M | $743M | $231M |
CGEN vs ABSI vs RXRX vs SDGR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 21 | May 26 | Return |
|---|---|---|---|
| Compugen Ltd. (CGEN) | 100 | 42.7 | -57.3% |
| Absci Corporation (ABSI) | 100 | 20.7 | -79.3% |
| Recursion Pharmaceu… (RXRX) | 100 | 10.9 | -89.1% |
| Schrödinger, Inc. (SDGR) | 100 | 19.4 | -80.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CGEN vs ABSI vs RXRX vs SDGR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CGEN carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.65
- -56.7% 10Y total return vs SDGR's -54.2%
- Lower volatility, beta 1.65, Low D/E 5.3%, current ratio 5.26x
- Beta 1.65, current ratio 5.26x
ABSI lags the leaders in this set but could rank higher in a more targeted comparison.
RXRX is the clearest fit if your priority is growth exposure.
- Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
- 26.9% revenue growth vs ABSI's -38.2%
SDGR is the #2 pick in this set and the best alternative if quality and efficiency is your priority.
- -40.6% margin vs ABSI's -73.1%
- -15.3% ROA vs ABSI's -54.7%, ROIC -39.4% vs -58.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 26.9% revenue growth vs ABSI's -38.2% | |
| Value | Better valuation composite | |
| Quality / Margins | -40.6% margin vs ABSI's -73.1% | |
| Stability / Safety | Beta 1.65 vs RXRX's 2.99, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +124.8% vs SDGR's -45.0% | |
| Efficiency (ROA) | -15.3% ROA vs ABSI's -54.7%, ROIC -39.4% vs -58.0% |
CGEN vs ABSI vs RXRX vs SDGR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
CGEN vs ABSI vs RXRX vs SDGR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
CGEN leads in 3 of 6 categories
SDGR leads 1 • ABSI leads 0 • RXRX leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
SDGR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
SDGR is the larger business by revenue, generating $255M annually — 157.3x ABSI's $2M. SDGR is the more profitable business, keeping -40.6% of every revenue dollar as net income compared to ABSI's -73.1%. On growth, SDGR holds the edge at -1.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $5M | $2M | $66M | $255M |
| EBITDAEarnings before interest/tax | -$33M | -$116M | -$501M | -$159M |
| Net IncomeAfter-tax profit | -$31M | -$118M | -$560M | -$103M |
| Free Cash FlowCash after capex | $0 | -$99M | -$326M | -$148M |
| Gross MarginGross profit ÷ Revenue | -5.2% | -13.4% | -34.4% | +55.3% |
| Operating MarginEBIT ÷ Revenue | -6.5% | -60.3% | -8.8% | -64.7% |
| Net MarginNet income ÷ Revenue | -5.8% | -73.1% | -8.4% | -40.6% |
| FCF MarginFCF ÷ Revenue | +177.6% | -60.8% | -4.9% | -58.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -100.0% | -56.1% | -1.6% |
| EPS Growth (YoY)Latest quarter vs prior year | — | +9.5% | +56.0% | +1.2% |
Valuation Metrics
CGEN leads this category, winning 2 of 4 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $260M | $917M | $1.5B | $981M |
| Enterprise ValueMkt cap + debt − cash | $244M | $902M | $819M | $860M |
| Trailing P/EPrice ÷ TTM EPS | -18.13x | -7.02x | -2.31x | -9.31x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 9.32x | 327.55x | 19.88x | 3.83x |
| Price / BookPrice ÷ Book value/share | 4.73x | 4.26x | 1.31x | 2.65x |
| Price / FCFMarket cap ÷ FCF | 5.25x | — | — | 78.76x |
Profitability & Efficiency
CGEN leads this category, winning 3 of 8 comparable metrics.
Profitability & Efficiency
SDGR delivers a -30.8% return on equity — every $100 of shareholder capital generates $-31 in annual profit, vs $-72 for CGEN. ABSI carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to SDGR's 0.30x.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -71.5% | -63.6% | -54.3% | -30.8% |
| ROA (TTM)Return on assets | -32.0% | -54.7% | -40.6% | -15.3% |
| ROICReturn on invested capital | -24.1% | -58.0% | -95.8% | -39.4% |
| ROCEReturn on capital employed | -15.7% | -65.9% | -50.1% | -28.6% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.05x | 0.03x | 0.07x | 0.30x |
| Net DebtTotal debt minus cash | -$15M | -$15M | -$665M | -$121M |
| Cash & Equiv.Liquid assets | $18M | $20M | $743M | $231M |
| Total DebtShort + long-term debt | $3M | $5M | $78M | $109M |
| Interest CoverageEBIT ÷ Interest expense | -437.97x | -865.97x | -342.92x | — |
Total Returns (Dividends Reinvested)
CGEN leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CGEN five years ago would be worth $4,045 today (with dividends reinvested), compared to $1,441 for RXRX. Over the past 12 months, CGEN leads with a +124.8% total return vs SDGR's -45.0%. The 3-year compound annual growth rate (CAGR) favors CGEN at 63.4% vs SDGR's -22.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +87.1% | +63.4% | -21.0% | -27.0% |
| 1-Year ReturnPast 12 months | +124.8% | +110.7% | -24.4% | -45.0% |
| 3-Year ReturnCumulative with dividends | +336.1% | +315.5% | -40.7% | -52.7% |
| 5-Year ReturnCumulative with dividends | -59.6% | -72.7% | -85.6% | -79.5% |
| 10-Year ReturnCumulative with dividends | -56.7% | -72.7% | -81.6% | -54.2% |
| CAGR (3Y)Annualised 3-year return | +63.4% | +60.8% | -16.0% | -22.1% |
Risk & Volatility
Evenly matched — CGEN and ABSI each lead in 1 of 2 comparable metrics.
Risk & Volatility
CGEN is the less volatile stock with a 1.65 beta — it tends to amplify market swings less than RXRX's 2.99 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABSI currently trades 94.6% from its 52-week high vs RXRX's 46.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.65x | 2.77x | 2.99x | 1.65x |
| 52-Week HighHighest price in past year | $3.23 | $6.24 | $7.18 | $27.63 |
| 52-Week LowLowest price in past year | $1.25 | $2.24 | $2.80 | $10.95 |
| % of 52W HighCurrent price vs 52-week peak | +89.6% | +94.6% | +46.2% | +47.5% |
| RSI (14)Momentum oscillator 0–100 | 60.1 | 77.8 | 44.4 | 62.7 |
| Avg Volume (50D)Average daily shares traded | 435K | 4.5M | 12.5M | 1.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: CGEN as "Buy", ABSI as "Buy", RXRX as "Hold", SDGR as "Buy". Consensus price targets imply 231.3% upside for RXRX (target: $11) vs 4.4% for ABSI (target: $6).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $4.00 | $6.16 | $11.00 | $18.00 |
| # AnalystsCovering analysts | 13 | 12 | 10 | 12 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
CGEN leads in 3 of 6 categories (Valuation Metrics, Profitability & Efficiency). SDGR leads in 1 (Income & Cash Flow). 1 tied.
CGEN vs ABSI vs RXRX vs SDGR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is CGEN or ABSI or RXRX or SDGR a better buy right now?
For growth investors, Recursion Pharmaceuticals, Inc.
(RXRX) is the stronger pick with 26. 9% revenue growth year-over-year, versus -38. 2% for Absci Corporation (ABSI). Analysts rate Compugen Ltd. (CGEN) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CGEN or ABSI or RXRX or SDGR?
Over the past 5 years, Compugen Ltd.
(CGEN) delivered a total return of -59. 6%, compared to -85. 6% for Recursion Pharmaceuticals, Inc. (RXRX). Over 10 years, the gap is even starker: SDGR returned -54. 2% versus RXRX's -81. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CGEN or ABSI or RXRX or SDGR?
By beta (market sensitivity over 5 years), Compugen Ltd.
(CGEN) is the lower-risk stock at 1. 65β versus Recursion Pharmaceuticals, Inc. 's 2. 99β — meaning RXRX is approximately 81% more volatile than CGEN relative to the S&P 500. On balance sheet safety, Absci Corporation (ABSI) carries a lower debt/equity ratio of 3% versus 30% for Schrödinger, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CGEN or ABSI or RXRX or SDGR?
By revenue growth (latest reported year), Recursion Pharmaceuticals, Inc.
(RXRX) is pulling ahead at 26. 9% versus -38. 2% for Absci Corporation (ABSI). On earnings-per-share growth, the picture is similar: Schrödinger, Inc. grew EPS 45. 1% year-over-year, compared to 10. 6% for Absci Corporation. Over a 3-year CAGR, CGEN leads at 66. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CGEN or ABSI or RXRX or SDGR?
Schrödinger, Inc.
(SDGR) is the more profitable company, earning -40. 4% net margin versus -41. 1% for Absci Corporation — meaning it keeps -40. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CGEN leads at -53. 4% versus -44. 5% for ABSI. At the gross margin level — before operating expenses — CGEN leads at 71. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CGEN or ABSI or RXRX or SDGR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CGEN or ABSI or RXRX or SDGR better for a retirement portfolio?
For long-horizon retirement investors, Schrödinger, Inc.
(SDGR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Recursion Pharmaceuticals, Inc. (RXRX) carries a higher beta of 2. 99 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SDGR: -54. 2%, RXRX: -81. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CGEN and ABSI and RXRX and SDGR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CGEN is a small-cap quality compounder stock; ABSI is a small-cap quality compounder stock; RXRX is a small-cap high-growth stock; SDGR is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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