CGTX
Cognition Therapeutics, Inc.
Biotechnology
Market Cap$85M
5Y Perf.-90.4%
Compare Stocks
2 / 10Try these comparisons:
Stock Comparison
CGTX vs AVXL
Revenue, margins, valuation, and 5-year total return — side by side.
AVXL
Anavex Life Sciences Corp.
Biotechnology
Market Cap$289M
5Y Perf.-83.4%
CGTX vs AVXL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | CGTX | AVXL |
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $85M | $289M |
| Revenue (TTM) | $0.00 | $0.00 |
| Net Income (TTM) | $-23M | $-40M |
| Total Debt | $638K | $0.00 |
| Cash & Equiv. | $37M | $103M |
CGTX vs AVXL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
CGTX
AVXL
| Stock | Oct 21 | May 26 | Return |
|---|---|---|---|
| Cognition Therapeut… (CGTX) | 100 | 9.6 | -90.4% |
| Anavex Life Science… (AVXL) | 100 | 16.6 | -83.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CGTX vs AVXL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: AVXL leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Cognition Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
CGTX
Cognition Therapeutics, Inc.
The Growth Play
CGTX is the clearest fit if your priority is growth exposure.
- EPS growth 62.4%
- 31.0% revenue growth vs AVXL's -34.9%
- +227.0% vs AVXL's -63.2%
Best for: growth exposure
AVXL
Anavex Life Sciences Corp.
The Income Pick
AVXL carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- beta 1.51
- -25.7% 10Y total return vs CGTX's -90.9%
- Lower volatility, beta 1.51, current ratio 11.60x
Best for: income & stability and long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | CGTX | 31.0% revenue growth vs AVXL's -34.9% |
| Quality / Margins | AVXL | 4.5% margin vs CGTX's -0.0% |
| Stability / Safety | AVXL | Beta 1.51 vs CGTX's 3.40 |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | CGTX | +227.0% vs AVXL's -63.2% |
| Efficiency (ROA) | AVXL | -30.0% ROA vs CGTX's -69.6% |
CGTX vs AVXL — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLCGTXLAGGINGAVXL
AVXLAnavex Life Sciences …
1leads
CGTXCognition Therapeutic…
1leads
6 Total Categories
CATEGORYLEADERvs AVXLMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
CGTX1/1
Valuation MetricsMultiples, price ratios, and targets
Tied
—
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
AVXL5/6
Total Returns1Y, 3Y, 5Y total returns with dividends
Tied
—
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
CGTX leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
CGTX and AVXL operate at a comparable scale, with $0 and $0 in trailing revenue.
| Metric | CGTXCognition Therape… | AVXLAnavex Life Scien… |
|---|---|---|
| RevenueTrailing 12 months | $0 | $0 |
| EBITDAEarnings before interest/tax | -$48M | -$30M |
| Net IncomeAfter-tax profit | -$23M | -$40M |
| Free Cash FlowCash after capex | -$25M | -$34M |
| Gross MarginGross profit ÷ Revenue | — | — |
| Operating MarginEBIT ÷ Revenue | — | — |
| Net MarginNet income ÷ Revenue | — | — |
| FCF MarginFCF ÷ Revenue | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | +77.9% | +54.4% |
CGTX leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
Evenly matched — CGTX and AVXL each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | CGTXCognition Therape… | AVXLAnavex Life Scien… |
|---|---|---|
| Market CapShares × price | $85M | $289M |
| Enterprise ValueMkt cap + debt − cash | $49M | $187M |
| Trailing P/EPrice ÷ TTM EPS | -3.63x | -5.78x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — |
| Price / BookPrice ÷ Book value/share | 2.46x | 2.81x |
| Price / FCFMarket cap ÷ FCF | — | — |
Evenly matched — CGTX and AVXL each lead in 1 of 2 comparable metrics.
Profitability & Efficiency
AVXL leads this category, winning 5 of 6 comparable metrics.
Profitability & Efficiency
AVXL delivers a -31.5% return on equity — every $100 of shareholder capital generates $-32 in annual profit, vs $-104 for CGTX. On the Piotroski fundamental quality scale (0–9), CGTX scores 3/9 vs AVXL's 2/9, reflecting mixed financial health.
| Metric | CGTXCognition Therape… | AVXLAnavex Life Scien… |
|---|---|---|
| ROE (TTM)Return on equity | -104.3% | -31.5% |
| ROA (TTM)Return on assets | -69.6% | -30.0% |
| ROICReturn on invested capital | — | — |
| ROCEReturn on capital employed | -178.5% | -47.8% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 |
| Debt / EquityFinancial leverage | 0.02x | — |
| Net DebtTotal debt minus cash | -$36M | -$103M |
| Cash & Equiv.Liquid assets | $37M | $103M |
| Total DebtShort + long-term debt | $638,000 | $0 |
| Interest CoverageEBIT ÷ Interest expense | -2600.54x | — |
AVXL leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
Evenly matched — CGTX and AVXL each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in AVXL five years ago would be worth $2,759 today (with dividends reinvested), compared to $908 for CGTX. Over the past 12 months, CGTX leads with a +227.0% total return vs AVXL's -63.2%. The 3-year compound annual growth rate (CAGR) favors CGTX at -10.4% vs AVXL's -28.1% — a key indicator of consistent wealth creation.
| Metric | CGTXCognition Therape… | AVXLAnavex Life Scien… |
|---|---|---|
| YTD ReturnYear-to-date | -21.1% | -15.2% |
| 1-Year ReturnPast 12 months | +227.0% | -63.2% |
| 3-Year ReturnCumulative with dividends | -28.0% | -62.9% |
| 5-Year ReturnCumulative with dividends | -90.9% | -72.4% |
| 10-Year ReturnCumulative with dividends | -90.9% | -25.7% |
| CAGR (3Y)Annualised 3-year return | -10.4% | -28.1% |
Evenly matched — CGTX and AVXL each lead in 3 of 6 comparable metrics.
Risk & Volatility
Evenly matched — CGTX and AVXL each lead in 1 of 2 comparable metrics.
Risk & Volatility
AVXL is the less volatile stock with a 1.51 beta — it tends to amplify market swings less than CGTX's 3.40 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CGTX currently trades 30.3% from its 52-week high vs AVXL's 22.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | CGTXCognition Therape… | AVXLAnavex Life Scien… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 3.40x | 1.51x |
| 52-Week HighHighest price in past year | $3.83 | $13.99 |
| 52-Week LowLowest price in past year | $0.22 | $2.61 |
| % of 52W HighCurrent price vs 52-week peak | +30.3% | +22.3% |
| RSI (14)Momentum oscillator 0–100 | 56.4 | 47.0 |
| Avg Volume (50D)Average daily shares traded | 1.2M | 1.4M |
Evenly matched — CGTX and AVXL each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates CGTX as "Buy" and AVXL as "Buy".
| Metric | CGTXCognition Therape… | AVXLAnavex Life Scien… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | — | $11.00 |
| # AnalystsCovering analysts | 7 | 13 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
CGTX leads in 1 of 6 categories (Income & Cash Flow). AVXL leads in 1 (Profitability & Efficiency). 3 tied.
Best OverallCognition Therapeutics, Inc. (CGTX)Leads 1 of 6 categories
Loading custom metrics...
CGTX vs AVXL: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is CGTX or AVXL a better buy right now?
Analysts rate Cognition Therapeutics, Inc.
(CGTX) a "Buy" — based on 7 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CGTX or AVXL?
Over the past 5 years, Anavex Life Sciences Corp.
(AVXL) delivered a total return of -72. 4%, compared to -90. 9% for Cognition Therapeutics, Inc. (CGTX). Over 10 years, the gap is even starker: AVXL returned -25. 7% versus CGTX's -90. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CGTX or AVXL?
By beta (market sensitivity over 5 years), Anavex Life Sciences Corp.
(AVXL) is the lower-risk stock at 1. 51β versus Cognition Therapeutics, Inc. 's 3. 40β — meaning CGTX is approximately 125% more volatile than AVXL relative to the S&P 500.
04Which is growing faster — CGTX or AVXL?
On earnings-per-share growth, the picture is similar: Cognition Therapeutics, Inc.
grew EPS 62. 4% year-over-year, compared to -3. 8% for Anavex Life Sciences Corp.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CGTX or AVXL?
Cognition Therapeutics, Inc.
(CGTX) is the more profitable company, earning 0. 0% net margin versus 0. 0% for Anavex Life Sciences Corp. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CGTX leads at 0. 0% versus 0. 0% for AVXL. At the gross margin level — before operating expenses — CGTX leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CGTX or AVXL?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CGTX or AVXL better for a retirement portfolio?
For long-horizon retirement investors, Anavex Life Sciences Corp.
(AVXL) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. Cognition Therapeutics, Inc. (CGTX) carries a higher beta of 3. 40 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (AVXL: -25. 7%, CGTX: -90. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CGTX and AVXL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.