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CLPT vs ANGO vs NVCR vs INVA vs ABT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CLPT
ClearPoint Neuro, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$343M
5Y Perf.+215.0%
ANGO
AngioDynamics, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$469M
5Y Perf.+9.7%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-73.5%
INVA
Innoviva, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.93B
5Y Perf.+63.9%
ABT
Abbott Laboratories

Medical - Devices

HealthcareNYSE • US
Market Cap$151.30B
5Y Perf.-11.2%

CLPT vs ANGO vs NVCR vs INVA vs ABT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CLPT logoCLPT
ANGO logoANGO
NVCR logoNVCR
INVA logoINVA
ABT logoABT
IndustryMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & SuppliesBiotechnologyMedical - Devices
Market Cap$343M$469M$1.92B$1.93B$151.30B
Revenue (TTM)$37M$307M$674M$424M$43.84B
Net Income (TTM)$-26M$-28M$-173M$504M$13.98B
Gross Margin61.4%53.7%75.2%76.2%54.0%
Operating Margin-65.4%-9.4%-27.2%14.8%17.8%
Forward P/E7.3x15.4x
Total Debt$58M$0.00$290M$269M$15.28B
Cash & Equiv.$46M$56M$103M$551M$7.62B

CLPT vs ANGO vs NVCR vs INVA vs ABTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CLPT
ANGO
NVCR
INVA
ABT
StockMay 20May 26Return
ClearPoint Neuro, I… (CLPT)100315.0+215.0%
AngioDynamics, Inc. (ANGO)100109.7+9.7%
NovoCure Limited (NVCR)10026.5-73.5%
Innoviva, Inc. (INVA)100163.9+63.9%
Abbott Laboratories (ABT)10088.8-11.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: CLPT vs ANGO vs NVCR vs INVA vs ABT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: INVA leads in 5 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. AngioDynamics, Inc. is the stronger pick specifically for recent price momentum and sentiment. ABT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
CLPT
ClearPoint Neuro, Inc.
The Healthcare Pick

CLPT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ANGO
AngioDynamics, Inc.
The Momentum Pick

ANGO is the #2 pick in this set and the best alternative if momentum is your priority.

  • +28.5% vs ABT's -33.2%
Best for: momentum
NVCR
NovoCure Limited
The Healthcare Pick

Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
INVA
Innoviva, Inc.
The Growth Play

INVA carries the broadest edge in this set and is the clearest fit for growth exposure and sleep-well-at-night.

  • Rev growth 18.5%, EPS growth 8.2%, 3Y rev CAGR 8.7%
  • Lower volatility, beta 0.13, Low D/E 22.9%, current ratio 14.64x
  • Beta 0.13, current ratio 14.64x
  • 18.5% revenue growth vs ANGO's -3.8%
Best for: growth exposure and sleep-well-at-night
ABT
Abbott Laboratories
The Income Pick

ABT ranks third and is worth considering specifically for income & stability and long-term compounding.

  • Dividend streak 11 yrs, beta 0.25, yield 2.5%
  • 173.7% 10Y total return vs INVA's 94.9%
  • PEG 0.51 vs INVA's 0.71
  • 2.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthINVA logoINVA18.5% revenue growth vs ANGO's -3.8%
ValueINVA logoINVABetter valuation composite
Quality / MarginsINVA logoINVA118.9% margin vs CLPT's -69.1%
Stability / SafetyINVA logoINVABeta 0.13 vs CLPT's 2.34, lower leverage
DividendsABT logoABT2.5% yield; 11-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)ANGO logoANGO+28.5% vs ABT's -33.2%
Efficiency (ROA)INVA logoINVA32.4% ROA vs CLPT's -40.7%, ROIC 14.2% vs -73.7%

CLPT vs ANGO vs NVCR vs INVA vs ABT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CLPTClearPoint Neuro, Inc.
FY 2025
Biologics and Drug Delivery Revenue
58.4%$19M
Biologics and Drug Delivery - Disposable Products
22.5%$7M
Capital Equipment and Software Revenue
9.5%$3M
Capital Equipment and Software - Systems and Software Products
5.2%$2M
Capital Equipment and Software - Services
4.3%$1M
ANGOAngioDynamics, Inc.
FY 2024
Med Device
65.0%$198M
Med Tech
35.0%$106M
NVCRNovoCure Limited

Segment breakdown not available.

INVAInnoviva, Inc.
FY 2025
Royalty
57.5%$236M
Product
41.8%$172M
License And Other Revenue
0.7%$3M
ABTAbbott Laboratories
FY 2024
Medical Devices
45.3%$19.0B
Diagnostic Products
22.3%$9.3B
Nutritional Products
20.1%$8.4B
Established Pharmaceutical Products
12.4%$5.2B

CLPT vs ANGO vs NVCR vs INVA vs ABT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLINVALAGGINGNVCR

Income & Cash Flow (Last 12 Months)

INVA leads this category, winning 4 of 6 comparable metrics.

ABT is the larger business by revenue, generating $43.8B annually — 1185.9x CLPT's $37M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to CLPT's -69.1%. On growth, CLPT holds the edge at +34.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCLPT logoCLPTClearPoint Neuro,…ANGO logoANGOAngioDynamics, In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
RevenueTrailing 12 months$37M$307M$674M$424M$43.8B
EBITDAEarnings before interest/tax-$22M-$5M-$165M$86M$10.9B
Net IncomeAfter-tax profit-$26M-$28M-$173M$504M$14.0B
Free Cash FlowCash after capex-$24M-$9M-$48M$181M$6.9B
Gross MarginGross profit ÷ Revenue+61.4%+53.7%+75.2%+76.2%+54.0%
Operating MarginEBIT ÷ Revenue-65.4%-9.4%-27.2%+14.8%+17.8%
Net MarginNet income ÷ Revenue-69.1%-9.0%-25.7%+118.9%+31.9%
FCF MarginFCF ÷ Revenue-66.1%-3.0%-7.1%+42.8%+15.8%
Rev. Growth (YoY)Latest quarter vs prior year+34.0%+9.0%+12.3%+10.6%+6.9%
EPS Growth (YoY)Latest quarter vs prior year-35.0%+42.3%-100.0%+4.0%0.0%
INVA leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

INVA leads this category, winning 4 of 7 comparable metrics.

At 6.9x trailing earnings, INVA trades at a 39% valuation discount to ABT's 11.4x P/E. Adjusting for growth (PEG ratio), ABT offers better value at 0.38x vs INVA's 0.67x — a lower PEG means you pay less per unit of expected earnings growth.

MetricCLPT logoCLPTClearPoint Neuro,…ANGO logoANGOAngioDynamics, In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
Market CapShares × price$343M$469M$1.9B$1.9B$151.3B
Enterprise ValueMkt cap + debt − cash$355M$413M$2.1B$1.7B$159.0B
Trailing P/EPrice ÷ TTM EPS-12.98x-13.58x-13.80x6.91x11.39x
Forward P/EPrice ÷ next-FY EPS est.7.31x15.40x
PEG RatioP/E ÷ EPS growth rate0.67x0.38x
EV / EBITDAEnterprise value multiple8.10x15.83x
Price / SalesMarket cap ÷ Revenue9.28x1.60x2.92x4.55x3.61x
Price / BookPrice ÷ Book value/share11.80x2.52x5.51x1.65x3.18x
Price / FCFMarket cap ÷ FCF9.88x23.82x
INVA leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

INVA leads this category, winning 7 of 9 comparable metrics.

INVA delivers a 46.5% return on equity — every $100 of shareholder capital generates $46 in annual profit, vs $-122 for CLPT. INVA carries lower financial leverage with a 0.23x debt-to-equity ratio, signaling a more conservative balance sheet compared to CLPT's 2.08x. On the Piotroski fundamental quality scale (0–9), ABT scores 7/9 vs CLPT's 4/9, reflecting strong financial health.

MetricCLPT logoCLPTClearPoint Neuro,…ANGO logoANGOAngioDynamics, In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
ROE (TTM)Return on equity-122.2%-15.7%-50.8%+46.5%+27.3%
ROA (TTM)Return on assets-40.7%-10.3%-16.5%+32.4%+16.6%
ROICReturn on invested capital-73.7%-22.9%-16.4%+14.2%+9.9%
ROCEReturn on capital employed-41.7%-18.6%-28.9%+12.4%+10.8%
Piotroski ScoreFundamental quality 0–945557
Debt / EquityFinancial leverage2.08x0.85x0.23x0.32x
Net DebtTotal debt minus cash$12M-$56M$187M-$282M$7.7B
Cash & Equiv.Liquid assets$46M$56M$103M$551M$7.6B
Total DebtShort + long-term debt$58M$0$290M$269M$15.3B
Interest CoverageEBIT ÷ Interest expense-18.31x-258.19x-96.80x63.45x19.22x
INVA leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

INVA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in INVA five years ago would be worth $19,437 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, ANGO leads with a +28.5% total return vs ABT's -33.2%. The 3-year compound annual growth rate (CAGR) favors INVA at 25.0% vs NVCR's -37.6% — a key indicator of consistent wealth creation.

MetricCLPT logoCLPTClearPoint Neuro,…ANGO logoANGOAngioDynamics, In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
YTD ReturnYear-to-date-16.7%-11.1%+28.3%+14.7%-28.9%
1-Year ReturnPast 12 months-12.1%+28.5%+1.1%+21.7%-33.2%
3-Year ReturnCumulative with dividends+21.7%+25.8%-75.7%+95.2%-15.4%
5-Year ReturnCumulative with dividends-38.3%-53.3%-91.3%+94.4%-17.9%
10-Year ReturnCumulative with dividends-25.1%-9.2%+30.3%+94.9%+173.7%
CAGR (3Y)Annualised 3-year return+6.8%+7.9%-37.6%+25.0%-5.4%
INVA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

INVA leads this category, winning 2 of 2 comparable metrics.

INVA is the less volatile stock with a 0.13 beta — it tends to amplify market swings less than CLPT's 2.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INVA currently trades 90.7% from its 52-week high vs CLPT's 38.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCLPT logoCLPTClearPoint Neuro,…ANGO logoANGOAngioDynamics, In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
Beta (5Y)Sensitivity to S&P 5002.30x1.26x2.15x0.11x0.22x
52-Week HighHighest price in past year$30.10$13.99$20.06$25.15$139.06
52-Week LowLowest price in past year$8.27$8.36$9.82$16.52$86.15
% of 52W HighCurrent price vs 52-week peak+38.8%+80.6%+83.9%+90.7%+62.6%
RSI (14)Momentum oscillator 0–10056.454.069.839.922.9
Avg Volume (50D)Average daily shares traded748K395K1.5M621K10.5M
INVA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

ABT leads this category, winning 1 of 1 comparable metric.

Analyst consensus: CLPT as "Buy", ANGO as "Hold", NVCR as "Buy", INVA as "Buy", ABT as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 46.4% for ANGO (target: $17). ABT is the only dividend payer here at 2.52% yield — a key consideration for income-focused portfolios.

MetricCLPT logoCLPTClearPoint Neuro,…ANGO logoANGOAngioDynamics, In…NVCR logoNVCRNovoCure LimitedINVA logoINVAInnoviva, Inc.ABT logoABTAbbott Laboratori…
Analyst RatingConsensus buy/hold/sellBuyHoldBuyBuyBuy
Price TargetConsensus 12-month target$18.00$16.50$33.50$40.00$128.71
# AnalystsCovering analysts311151041
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises011
Dividend / ShareAnnual DPS$2.19
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.4%0.0%+0.2%+0.9%
ABT leads this category, winning 1 of 1 comparable metric.
Key Takeaway

INVA leads in 5 of 6 categories (Income & Cash Flow, Valuation Metrics). ABT leads in 1 (Analyst Outlook).

Best OverallInnoviva, Inc. (INVA)Leads 5 of 6 categories
Loading custom metrics...

CLPT vs ANGO vs NVCR vs INVA vs ABT: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is CLPT or ANGO or NVCR or INVA or ABT a better buy right now?

For growth investors, Innoviva, Inc.

(INVA) is the stronger pick with 18. 5% revenue growth year-over-year, versus -3. 8% for AngioDynamics, Inc. (ANGO). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (7. 3x forward), making it the more compelling value choice. Analysts rate ClearPoint Neuro, Inc. (CLPT) a "Buy" — based on 3 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — CLPT or ANGO or NVCR or INVA or ABT?

On trailing P/E, Innoviva, Inc.

(INVA) is the cheapest at 6. 9x versus Abbott Laboratories at 11. 4x. On forward P/E, Innoviva, Inc. is actually cheaper at 7. 3x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Abbott Laboratories wins at 0. 51x versus Innoviva, Inc. 's 0. 71x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — CLPT or ANGO or NVCR or INVA or ABT?

Over the past 5 years, Innoviva, Inc.

(INVA) delivered a total return of +94. 4%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: ABT returned +166. 6% versus CLPT's -17. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — CLPT or ANGO or NVCR or INVA or ABT?

By beta (market sensitivity over 5 years), Innoviva, Inc.

(INVA) is the lower-risk stock at 0. 11β versus ClearPoint Neuro, Inc. 's 2. 30β — meaning CLPT is approximately 1925% more volatile than INVA relative to the S&P 500. On balance sheet safety, Innoviva, Inc. (INVA) carries a lower debt/equity ratio of 23% versus 2% for ClearPoint Neuro, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — CLPT or ANGO or NVCR or INVA or ABT?

By revenue growth (latest reported year), Innoviva, Inc.

(INVA) is pulling ahead at 18. 5% versus -3. 8% for AngioDynamics, Inc. (ANGO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -28. 6% for ClearPoint Neuro, Inc.. Over a 3-year CAGR, CLPT leads at 21. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — CLPT or ANGO or NVCR or INVA or ABT?

Innoviva, Inc.

(INVA) is the more profitable company, earning 63. 8% net margin versus -69. 1% for ClearPoint Neuro, Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -65. 4% for CLPT. At the gross margin level — before operating expenses — NVCR leads at 74. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is CLPT or ANGO or NVCR or INVA or ABT more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Abbott Laboratories (ABT) is the more undervalued stock at a PEG of 0. 51x versus Innoviva, Inc. 's 0. 71x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 7. 3x forward P/E versus 15. 4x for Abbott Laboratories — 8. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVCR: 99. 0% to $33. 50.

08

Which pays a better dividend — CLPT or ANGO or NVCR or INVA or ABT?

In this comparison, ABT (2.

5% yield) pays a dividend. CLPT, ANGO, NVCR, INVA do not pay a meaningful dividend and should not be held primarily for income.

09

Is CLPT or ANGO or NVCR or INVA or ABT better for a retirement portfolio?

For long-horizon retirement investors, Abbott Laboratories (ABT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

22), 2. 5% yield, +166. 6% 10Y return). ClearPoint Neuro, Inc. (CLPT) carries a higher beta of 2. 30 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ABT: +166. 6%, CLPT: -17. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between CLPT and ANGO and NVCR and INVA and ABT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CLPT is a small-cap high-growth stock; ANGO is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; INVA is a small-cap high-growth stock; ABT is a mid-cap deep-value stock. ABT pays a dividend while CLPT, ANGO, NVCR, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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