CNTB
Connect Biopharma Holdings Limited
Biotechnology
Market Cap$130M
5Y Perf.-84.3%
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Stock Comparison
CNTB vs DAWN
Revenue, margins, valuation, and 5-year total return — side by side.
DAWN
Day One Biopharmaceuticals, Inc.
Biotechnology
Market Cap$2.22B
5Y Perf.-9.5%
CNTB vs DAWN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | CNTB | DAWN |
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $130M | $2.22B |
| Revenue (TTM) | $26M | $158M |
| Net Income (TTM) | $-57M | $-107M |
| Gross Margin | 95.6% | 89.1% |
| Operating Margin | -223.4% | -80.8% |
| Total Debt | $178K | $3M |
| Cash & Equiv. | $78M | $197M |
CNTB vs DAWN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
CNTB
DAWN
| Stock | May 21 | May 26 | Return |
|---|---|---|---|
| Connect Biopharma H… (CNTB) | 100 | 15.7 | -84.3% |
| Day One Biopharmace… (DAWN) | 100 | 90.5 | -9.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CNTB vs DAWN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: DAWN leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and recent price momentum and sentiment. Connect Biopharma Holdings Limited is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
CNTB
Connect Biopharma Holdings Limited
The Growth Play
CNTB is the clearest fit if your priority is growth exposure and sleep-well-at-night.
- EPS growth 74.1%
- Lower volatility, beta -0.14, Low D/E 0.2%, current ratio 11.46x
- Beta -0.14, current ratio 11.46x
Best for: growth exposure and sleep-well-at-night
DAWN
Day One Biopharmaceuticals, Inc.
The Long-Run Compounder
DAWN carries the broadest edge in this set and is the clearest fit for long-term compounding.
- -8.4% 10Y total return vs CNTB's -87.4%
- -67.8% margin vs CNTB's -220.1%
- +241.7% vs CNTB's +191.3%
Best for: long-term compounding
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | CNTB | 72.2% revenue growth vs DAWN's 20.6% |
| Quality / Margins | DAWN | -67.8% margin vs CNTB's -220.1% |
| Stability / Safety | CNTB | Lower D/E ratio (0.2% vs 0.6%) |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | DAWN | +241.7% vs CNTB's +191.3% |
| Efficiency (ROA) | DAWN | -20.7% ROA vs CNTB's -69.4%, ROIC -30.5% vs -338.2% |
CNTB vs DAWN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
FY 2024
FY 2025
CNTB vs DAWN — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLDAWNLAGGINGCNTB
CNTBConnect Biopharma Hol…
1leads
DAWNDay One Biopharmaceut…
2leads
6 Total Categories
CATEGORYLEADERvs CNTBMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
DAWN5/6
Valuation MetricsMultiples, price ratios, and targets
CNTB2/3
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
Tied
—
Total Returns1Y, 3Y, 5Y total returns with dividends
DAWN4/6
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
DAWN leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
DAWN is the larger business by revenue, generating $158M annually — 6.1x CNTB's $26M. Profitability is closely matched — net margins range from -67.8% (DAWN) to -2.2% (CNTB). On growth, DAWN holds the edge at +83.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | CNTBConnect Biopharma… | DAWNDay One Biopharma… |
|---|---|---|
| RevenueTrailing 12 months | $26M | $158M |
| EBITDAEarnings before interest/tax | -$57M | -$124M |
| Net IncomeAfter-tax profit | -$57M | -$107M |
| Free Cash FlowCash after capex | -$54M | -$108M |
| Gross MarginGross profit ÷ Revenue | +95.6% | +89.1% |
| Operating MarginEBIT ÷ Revenue | -2.2% | -80.8% |
| Net MarginNet income ÷ Revenue | -2.2% | -67.8% |
| FCF MarginFCF ÷ Revenue | -2.1% | -68.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | -99.8% | +83.9% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.6% | +70.0% |
DAWN leads this category, winning 5 of 6 comparable metrics.
Valuation Metrics
CNTB leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | CNTBConnect Biopharma… | DAWNDay One Biopharma… |
|---|---|---|
| Market CapShares × price | $130M | $2.2B |
| Enterprise ValueMkt cap + debt − cash | $51M | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | -8.32x | -20.70x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 4.97x | 14.06x |
| Price / BookPrice ÷ Book value/share | 1.40x | 5.05x |
| Price / FCFMarket cap ÷ FCF | — | — |
CNTB leads this category, winning 2 of 3 comparable metrics.
Profitability & Efficiency
Evenly matched — CNTB and DAWN each lead in 4 of 8 comparable metrics.
Profitability & Efficiency
DAWN delivers a -23.4% return on equity — every $100 of shareholder capital generates $-23 in annual profit, vs $-80 for CNTB. CNTB carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DAWN's 0.01x. On the Piotroski fundamental quality scale (0–9), CNTB scores 5/9 vs DAWN's 4/9, reflecting solid financial health.
| Metric | CNTBConnect Biopharma… | DAWNDay One Biopharma… |
|---|---|---|
| ROE (TTM)Return on equity | -80.4% | -23.4% |
| ROA (TTM)Return on assets | -69.4% | -20.7% |
| ROICReturn on invested capital | -3.4% | -30.5% |
| ROCEReturn on capital employed | -23.2% | -26.7% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.01x |
| Net DebtTotal debt minus cash | -$78M | -$194M |
| Cash & Equiv.Liquid assets | $78M | $197M |
| Total DebtShort + long-term debt | $178,000 | $3M |
| Interest CoverageEBIT ÷ Interest expense | -5993.94x | — |
Evenly matched — CNTB and DAWN each lead in 4 of 8 comparable metrics.
Total Returns (Dividends Reinvested)
DAWN leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in DAWN five years ago would be worth $9,162 today (with dividends reinvested), compared to $1,500 for CNTB. Over the past 12 months, DAWN leads with a +241.7% total return vs CNTB's +191.3%. The 3-year compound annual growth rate (CAGR) favors CNTB at 25.5% vs DAWN's 18.2% — a key indicator of consistent wealth creation.
| Metric | CNTBConnect Biopharma… | DAWNDay One Biopharma… |
|---|---|---|
| YTD ReturnYear-to-date | -7.5% | +143.3% |
| 1-Year ReturnPast 12 months | +191.3% | +241.7% |
| 3-Year ReturnCumulative with dividends | +97.5% | +65.1% |
| 5-Year ReturnCumulative with dividends | -85.0% | -8.4% |
| 10-Year ReturnCumulative with dividends | -87.4% | -8.4% |
| CAGR (3Y)Annualised 3-year return | +25.5% | +18.2% |
DAWN leads this category, winning 4 of 6 comparable metrics.
Risk & Volatility
Evenly matched — CNTB and DAWN each lead in 1 of 2 comparable metrics.
Risk & Volatility
CNTB is the less volatile stock with a -0.14 beta — it tends to amplify market swings less than DAWN's 0.35 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DAWN currently trades 100.0% from its 52-week high vs CNTB's 61.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | CNTBConnect Biopharma… | DAWNDay One Biopharma… |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.14x | 0.35x |
| 52-Week HighHighest price in past year | $3.82 | $21.53 |
| 52-Week LowLowest price in past year | $0.70 | $5.64 |
| % of 52W HighCurrent price vs 52-week peak | +61.0% | +100.0% |
| RSI (14)Momentum oscillator 0–100 | 42.8 | 80.3 |
| Avg Volume (50D)Average daily shares traded | 272K | 4.9M |
Evenly matched — CNTB and DAWN each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates CNTB as "Buy" and DAWN as "Buy". Consensus price targets imply 286.3% upside for CNTB (target: $9) vs 10.3% for DAWN (target: $24).
| Metric | CNTBConnect Biopharma… | DAWNDay One Biopharma… |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $9.00 | $23.75 |
| # AnalystsCovering analysts | 5 | 12 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
DAWN leads in 2 of 6 categories (Income & Cash Flow, Total Returns). CNTB leads in 1 (Valuation Metrics). 2 tied.
Best OverallDay One Biopharmaceuticals,… (DAWN)Leads 2 of 6 categories
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CNTB vs DAWN: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is CNTB or DAWN a better buy right now?
Analysts rate Connect Biopharma Holdings Limited (CNTB) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison.
The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CNTB or DAWN?
Over the past 5 years, Day One Biopharmaceuticals, Inc.
(DAWN) delivered a total return of -8. 4%, compared to -85. 0% for Connect Biopharma Holdings Limited (CNTB). Over 10 years, the gap is even starker: DAWN returned -8. 4% versus CNTB's -87. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CNTB or DAWN?
By beta (market sensitivity over 5 years), Connect Biopharma Holdings Limited (CNTB) is the lower-risk stock at -0.
14β versus Day One Biopharmaceuticals, Inc. 's 0. 35β — meaning DAWN is approximately -356% more volatile than CNTB relative to the S&P 500. On balance sheet safety, Connect Biopharma Holdings Limited (CNTB) carries a lower debt/equity ratio of 0% versus 1% for Day One Biopharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CNTB or DAWN?
On earnings-per-share growth, the picture is similar: Connect Biopharma Holdings Limited grew EPS 74.
1% year-over-year, compared to -2. 0% for Day One Biopharmaceuticals, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CNTB or DAWN?
Connect Biopharma Holdings Limited (CNTB) is the more profitable company, earning -60.
0% net margin versus -67. 8% for Day One Biopharmaceuticals, Inc. — meaning it keeps -60. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DAWN leads at -80. 8% versus -86. 2% for CNTB. At the gross margin level — before operating expenses — CNTB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CNTB or DAWN?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CNTB or DAWN better for a retirement portfolio?
For long-horizon retirement investors, Connect Biopharma Holdings Limited (CNTB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
14)). Both have compounded well over 10 years (CNTB: -87. 4%, DAWN: -8. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CNTB and DAWN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CNTB is a small-cap quality compounder stock; DAWN is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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