COCP
Cocrystal Pharma, Inc.
Biotechnology
Market Cap$18M
5Y Perf.-88.1%
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Stock Comparison
COCP vs GILD
Revenue, margins, valuation, and 5-year total return — side by side.
GILD
Gilead Sciences, Inc.
Drug Manufacturers - General
Market Cap$166.40B
5Y Perf.+72.2%
COCP vs GILD — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | COCP | GILD |
|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General |
| Market Cap | $18M | $166.40B |
| Revenue (TTM) | $0.00 | $29.73B |
| Net Income (TTM) | $-10M | $9.22B |
| Gross Margin | — | 63.0% |
| Operating Margin | — | 38.2% |
| Forward P/E | — | 15.7x |
| Total Debt | $2M | $24.59B |
| Cash & Equiv. | $10M | $7.56B |
COCP vs GILD — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
COCP
GILD
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Cocrystal Pharma, I… (COCP) | 100 | 11.9 | -88.1% |
| Gilead Sciences, In… (GILD) | 100 | 172.2 | +72.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: COCP vs GILD
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: GILD leads in 5 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Cocrystal Pharma, Inc. is the stronger pick specifically for growth and revenue expansion. As sector peers, any of these can serve as alternatives in the same allocation.
COCP
Cocrystal Pharma, Inc.
The Defensive Pick
COCP is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.36, Low D/E 19.0%, current ratio 4.77x
- 48.4% revenue growth vs GILD's 2.4%
Best for: sleep-well-at-night
GILD
Gilead Sciences, Inc.
The Income Pick
GILD carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 11 yrs, beta 0.66, yield 2.4%
- Rev growth 2.4%, EPS growth 16.8%, 3Y rev CAGR 2.6%
- 87.8% 10Y total return vs COCP's -99.4%
Best for: income & stability and growth exposure
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | COCP | 48.4% revenue growth vs GILD's 2.4% |
| Quality / Margins | GILD | 31.0% margin vs COCP's 4.0% |
| Stability / Safety | GILD | Beta 0.66 vs COCP's 1.36 |
| Dividends | GILD | 2.4% yield; 11-year raise streak; the other pay no meaningful dividend |
| Momentum (1Y) | GILD | +38.8% vs COCP's -11.5% |
| Efficiency (ROA) | GILD | 16.1% ROA vs COCP's -92.6%, ROIC 23.4% vs -8.0% |
COCP vs GILD — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
FY 2025
COCP vs GILD — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLGILDLAGGINGCOCP
COCPCocrystal Pharma, Inc.
2leads
GILDGilead Sciences, Inc.
3leads
6 Total Categories
CATEGORYLEADERvs COCPMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
COCP1/1
Valuation MetricsMultiples, price ratios, and targets
COCP2/2
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
GILD5/8
Total Returns1Y, 3Y, 5Y total returns with dividends
GILD5/6
Risk & VolatilityBeta, volatility, and downside exposure
GILD2/2
Analyst OutlookRatings, price targets, and dividends
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—
Income & Cash Flow (Last 12 Months)
COCP leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
GILD and COCP operate at a comparable scale, with $29.7B and $0 in trailing revenue.
| Metric | COCPCocrystal Pharma,… | GILDGilead Sciences, … |
|---|---|---|
| RevenueTrailing 12 months | $0 | $29.7B |
| EBITDAEarnings before interest/tax | -$10M | $12.1B |
| Net IncomeAfter-tax profit | -$10M | $9.2B |
| Free Cash FlowCash after capex | -$10M | $10.3B |
| Gross MarginGross profit ÷ Revenue | — | +63.0% |
| Operating MarginEBIT ÷ Revenue | — | +38.2% |
| Net MarginNet income ÷ Revenue | — | +31.0% |
| FCF MarginFCF ÷ Revenue | — | +34.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +4.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +61.2% | +54.8% |
COCP leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
COCP leads this category, winning 2 of 2 comparable metrics.
Valuation Metrics
| Metric | COCPCocrystal Pharma,… | GILDGilead Sciences, … |
|---|---|---|
| Market CapShares × price | $18M | $166.4B |
| Enterprise ValueMkt cap + debt − cash | $10M | $183.4B |
| Trailing P/EPrice ÷ TTM EPS | -0.81x | 19.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 15.69x |
| PEG RatioP/E ÷ EPS growth rate | — | 0.15x |
| EV / EBITDAEnterprise value multiple | — | 16.95x |
| Price / SalesMarket cap ÷ Revenue | — | 5.65x |
| Price / BookPrice ÷ Book value/share | 1.49x | 7.44x |
| Price / FCFMarket cap ÷ FCF | — | 17.60x |
COCP leads this category, winning 2 of 2 comparable metrics.
Profitability & Efficiency
GILD leads this category, winning 5 of 8 comparable metrics.
Profitability & Efficiency
GILD delivers a 42.3% return on equity — every $100 of shareholder capital generates $42 in annual profit, vs $-126 for COCP. COCP carries lower financial leverage with a 0.19x debt-to-equity ratio, signaling a more conservative balance sheet compared to GILD's 1.09x. On the Piotroski fundamental quality scale (0–9), GILD scores 9/9 vs COCP's 1/9, reflecting strong financial health.
| Metric | COCPCocrystal Pharma,… | GILDGilead Sciences, … |
|---|---|---|
| ROE (TTM)Return on equity | -126.1% | +42.3% |
| ROA (TTM)Return on assets | -92.6% | +16.1% |
| ROICReturn on invested capital | -8.0% | +23.4% |
| ROCEReturn on capital employed | -91.6% | +25.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 9 |
| Debt / EquityFinancial leverage | 0.19x | 1.09x |
| Net DebtTotal debt minus cash | -$8M | $17.0B |
| Cash & Equiv.Liquid assets | $10M | $7.6B |
| Total DebtShort + long-term debt | $2M | $24.6B |
| Interest CoverageEBIT ÷ Interest expense | — | 8.87x |
GILD leads this category, winning 5 of 8 comparable metrics.
Total Returns (Dividends Reinvested)
GILD leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in GILD five years ago would be worth $22,418 today (with dividends reinvested), compared to $878 for COCP. Over the past 12 months, GILD leads with a +38.8% total return vs COCP's -11.5%. The 3-year compound annual growth rate (CAGR) favors GILD at 22.2% vs COCP's -20.4% — a key indicator of consistent wealth creation.
| Metric | COCPCocrystal Pharma,… | GILDGilead Sciences, … |
|---|---|---|
| YTD ReturnYear-to-date | +40.4% | +10.9% |
| 1-Year ReturnPast 12 months | -11.5% | +38.8% |
| 3-Year ReturnCumulative with dividends | -49.6% | +82.4% |
| 5-Year ReturnCumulative with dividends | -91.2% | +124.2% |
| 10-Year ReturnCumulative with dividends | -99.4% | +87.8% |
| CAGR (3Y)Annualised 3-year return | -20.4% | +22.2% |
GILD leads this category, winning 5 of 6 comparable metrics.
Risk & Volatility
GILD leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
GILD is the less volatile stock with a 0.66 beta — it tends to amplify market swings less than COCP's 1.36 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GILD currently trades 85.2% from its 52-week high vs COCP's 52.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | COCPCocrystal Pharma,… | GILDGilead Sciences, … |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.36x | 0.66x |
| 52-Week HighHighest price in past year | $2.67 | $157.29 |
| 52-Week LowLowest price in past year | $0.86 | $95.30 |
| % of 52W HighCurrent price vs 52-week peak | +52.1% | +85.2% |
| RSI (14)Momentum oscillator 0–100 | 54.0 | 52.6 |
| Avg Volume (50D)Average daily shares traded | 2.9M | 5.8M |
GILD leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
GILD is the only dividend payer here at 2.38% yield — a key consideration for income-focused portfolios.
| Metric | COCPCocrystal Pharma,… | GILDGilead Sciences, … |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy |
| Price TargetConsensus 12-month target | — | $161.88 |
| # AnalystsCovering analysts | — | 58 |
| Dividend YieldAnnual dividend ÷ price | — | +2.4% |
| Dividend StreakConsecutive years of raises | — | 11 |
| Dividend / ShareAnnual DPS | — | $3.19 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.2% |
Insufficient data to determine a leader in this category.
Key Takeaway
GILD leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). COCP leads in 2 (Income & Cash Flow, Valuation Metrics).
Best OverallGilead Sciences, Inc. (GILD)Leads 3 of 6 categories
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COCP vs GILD: Frequently Asked Questions
7 questions · data-driven answers · updated daily
01Is COCP or GILD a better buy right now?
Gilead Sciences, Inc.
(GILD) offers the better valuation at 19. 8x trailing P/E (15. 7x forward), making it the more compelling value choice. Analysts rate Gilead Sciences, Inc. (GILD) a "Buy" — based on 58 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — COCP or GILD?
Over the past 5 years, Gilead Sciences, Inc.
(GILD) delivered a total return of +124. 2%, compared to -91. 2% for Cocrystal Pharma, Inc. (COCP). Over 10 years, the gap is even starker: GILD returned +87. 8% versus COCP's -99. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — COCP or GILD?
By beta (market sensitivity over 5 years), Gilead Sciences, Inc.
(GILD) is the lower-risk stock at 0. 66β versus Cocrystal Pharma, Inc. 's 1. 36β — meaning COCP is approximately 107% more volatile than GILD relative to the S&P 500. On balance sheet safety, Cocrystal Pharma, Inc. (COCP) carries a lower debt/equity ratio of 19% versus 109% for Gilead Sciences, Inc. — giving it more financial flexibility in a downturn.
04Which has better profit margins — COCP or GILD?
Gilead Sciences, Inc.
(GILD) is the more profitable company, earning 28. 9% net margin versus 0. 0% for Cocrystal Pharma, Inc. — meaning it keeps 28. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: GILD leads at 40. 1% versus 0. 0% for COCP. At the gross margin level — before operating expenses — GILD leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
05Which pays a better dividend — COCP or GILD?
In this comparison, GILD (2.
4% yield) pays a dividend. COCP does not pay a meaningful dividend and should not be held primarily for income.
06Is COCP or GILD better for a retirement portfolio?
For long-horizon retirement investors, Gilead Sciences, Inc.
(GILD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), 2. 4% yield). Both have compounded well over 10 years (GILD: +87. 8%, COCP: -99. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
07What are the main differences between COCP and GILD?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
GILD pays a dividend while COCP does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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