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Stock Comparison

COCP vs GILD vs ABBV vs REGN

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
COCP
Cocrystal Pharma, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$18M
5Y Perf.-88.1%
GILD
Gilead Sciences, Inc.

Drug Manufacturers - General

HealthcareNASDAQ • US
Market Cap$166.40B
5Y Perf.+72.2%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$358.42B
5Y Perf.+118.7%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$73.68B
5Y Perf.+15.7%

COCP vs GILD vs ABBV vs REGN — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
COCP logoCOCP
GILD logoGILD
ABBV logoABBV
REGN logoREGN
IndustryBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralBiotechnology
Market Cap$18M$166.40B$358.42B$73.68B
Revenue (TTM)$0.00$29.73B$61.16B$14.92B
Net Income (TTM)$-10M$9.22B$4.23B$4.42B
Gross Margin63.0%70.2%84.5%
Operating Margin38.2%26.7%24.3%
Forward P/E15.7x14.3x15.3x
Total Debt$2M$24.59B$69.07B$2.71B
Cash & Equiv.$10M$7.56B$5.23B$3.12B

COCP vs GILD vs ABBV vs REGNLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

COCP
GILD
ABBV
REGN
StockMay 20May 26Return
Cocrystal Pharma, I… (COCP)10011.9-88.1%
Gilead Sciences, In… (GILD)100172.2+72.2%
AbbVie Inc. (ABBV)100218.7+118.7%
Regeneron Pharmaceu… (REGN)100115.7+15.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: COCP vs GILD vs ABBV vs REGN

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: GILD leads in 4 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. AbbVie Inc. is the stronger pick specifically for capital preservation and lower volatility and dividend income and shareholder returns. COCP also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
COCP
Cocrystal Pharma, Inc.
The Growth Leader

COCP is the clearest fit if your priority is growth.

  • 48.4% revenue growth vs REGN's 1.0%
Best for: growth
GILD
Gilead Sciences, Inc.
The Growth Play

GILD carries the broadest edge in this set and is the clearest fit for growth exposure and valuation efficiency.

  • Rev growth 2.4%, EPS growth 16.8%, 3Y rev CAGR 2.6%
  • PEG 0.15 vs REGN's 2.43
  • PEG 0.15 vs 2.43
  • 31.0% margin vs COCP's 4.0%
Best for: growth exposure and valuation efficiency
ABBV
AbbVie Inc.
The Income Pick

ABBV is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.

  • Dividend streak 13 yrs, beta 0.34, yield 3.2%
  • 295.5% 10Y total return vs GILD's 87.8%
  • Beta 0.34, yield 3.2%, current ratio 0.67x
  • Beta 0.34 vs COCP's 1.36
Best for: income & stability and long-term compounding
REGN
Regeneron Pharmaceuticals, Inc.
The Defensive Pick

REGN is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
Best for: sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthCOCP logoCOCP48.4% revenue growth vs REGN's 1.0%
ValueGILD logoGILDPEG 0.15 vs 2.43
Quality / MarginsGILD logoGILD31.0% margin vs COCP's 4.0%
Stability / SafetyABBV logoABBVBeta 0.34 vs COCP's 1.36
DividendsABBV logoABBV3.2% yield, 13-year raise streak, vs GILD's 2.4%, (1 stock pays no dividend)
Momentum (1Y)GILD logoGILD+38.8% vs COCP's -11.5%
Efficiency (ROA)GILD logoGILD16.1% ROA vs COCP's -92.6%, ROIC 23.4% vs -8.0%

COCP vs GILD vs ABBV vs REGN — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

COCPCocrystal Pharma, Inc.

Segment breakdown not available.

GILDGilead Sciences, Inc.
FY 2025
Products, Other HIV
79.7%$20.8B
Cell Therapy Products, Total Cell Therapy Product Sales
8.4%$2.2B
Trodelvy
5.4%$1.4B
Veklury
3.5%$911M
Other Products, Total Other product sales
3.1%$799M
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B
REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M

COCP vs GILD vs ABBV vs REGN — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLGILDLAGGINGREGN

Income & Cash Flow (Last 12 Months)

GILD leads this category, winning 3 of 6 comparable metrics.

ABBV and COCP operate at a comparable scale, with $61.2B and $0 in trailing revenue. GILD is the more profitable business, keeping 31.0% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCOCP logoCOCPCocrystal Pharma,…GILD logoGILDGilead Sciences, …ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…
RevenueTrailing 12 months$0$29.7B$61.2B$14.9B
EBITDAEarnings before interest/tax-$10M$12.1B$24.5B$4.2B
Net IncomeAfter-tax profit-$10M$9.2B$4.2B$4.4B
Free Cash FlowCash after capex-$10M$10.3B$18.7B$4.2B
Gross MarginGross profit ÷ Revenue+63.0%+70.2%+84.5%
Operating MarginEBIT ÷ Revenue+38.2%+26.7%+24.3%
Net MarginNet income ÷ Revenue+31.0%+6.9%+29.6%
FCF MarginFCF ÷ Revenue+34.8%+30.6%+27.9%
Rev. Growth (YoY)Latest quarter vs prior year+4.4%+10.0%+19.0%
EPS Growth (YoY)Latest quarter vs prior year+61.2%+54.8%+57.4%-7.2%
GILD leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — COCP and GILD and ABBV each lead in 2 of 7 comparable metrics.

At 17.1x trailing earnings, REGN trades at a 80% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), GILD offers better value at 0.15x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.

MetricCOCP logoCOCPCocrystal Pharma,…GILD logoGILDGilead Sciences, …ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…
Market CapShares × price$18M$166.4B$358.4B$73.7B
Enterprise ValueMkt cap + debt − cash$10M$183.4B$422.3B$73.3B
Trailing P/EPrice ÷ TTM EPS-0.81x19.77x85.50x17.09x
Forward P/EPrice ÷ next-FY EPS est.15.69x14.28x15.35x
PEG RatioP/E ÷ EPS growth rate0.15x2.70x
EV / EBITDAEnterprise value multiple16.95x14.96x17.78x
Price / SalesMarket cap ÷ Revenue5.65x5.86x5.14x
Price / BookPrice ÷ Book value/share1.49x7.44x2.46x
Price / FCFMarket cap ÷ FCF17.60x20.12x18.06x
Evenly matched — COCP and GILD and ABBV each lead in 2 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — GILD and REGN each lead in 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-126 for COCP. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to GILD's 1.09x. On the Piotroski fundamental quality scale (0–9), GILD scores 9/9 vs COCP's 1/9, reflecting strong financial health.

MetricCOCP logoCOCPCocrystal Pharma,…GILD logoGILDGilead Sciences, …ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…
ROE (TTM)Return on equity-126.1%+42.3%+62.1%+14.3%
ROA (TTM)Return on assets-92.6%+16.1%+3.1%+11.1%
ROICReturn on invested capital-8.0%+23.4%+23.9%+8.9%
ROCEReturn on capital employed-91.6%+25.1%+21.5%+10.2%
Piotroski ScoreFundamental quality 0–91965
Debt / EquityFinancial leverage0.19x1.09x0.09x
Net DebtTotal debt minus cash-$8M$17.0B$63.8B-$412M
Cash & Equiv.Liquid assets$10M$7.6B$5.2B$3.1B
Total DebtShort + long-term debt$2M$24.6B$69.1B$2.7B
Interest CoverageEBIT ÷ Interest expense8.87x3.28x108.44x
Evenly matched — GILD and REGN each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GILD leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in GILD five years ago would be worth $22,418 today (with dividends reinvested), compared to $878 for COCP. Over the past 12 months, GILD leads with a +38.8% total return vs COCP's -11.5%. The 3-year compound annual growth rate (CAGR) favors GILD at 22.2% vs COCP's -20.4% — a key indicator of consistent wealth creation.

MetricCOCP logoCOCPCocrystal Pharma,…GILD logoGILDGilead Sciences, …ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…
YTD ReturnYear-to-date+40.4%+10.9%-10.1%-8.5%
1-Year ReturnPast 12 months-11.5%+38.8%+11.3%+27.1%
3-Year ReturnCumulative with dividends-49.6%+82.4%+50.4%-5.1%
5-Year ReturnCumulative with dividends-91.2%+124.2%+101.3%+43.6%
10-Year ReturnCumulative with dividends-99.4%+87.8%+295.5%+90.0%
CAGR (3Y)Annualised 3-year return-20.4%+22.2%+14.6%-1.7%
GILD leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ABBV and REGN each lead in 1 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than COCP's 1.36 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. REGN currently trades 86.4% from its 52-week high vs COCP's 52.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCOCP logoCOCPCocrystal Pharma,…GILD logoGILDGilead Sciences, …ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…
Beta (5Y)Sensitivity to S&P 5001.36x0.66x0.34x0.81x
52-Week HighHighest price in past year$2.67$157.29$244.81$821.11
52-Week LowLowest price in past year$0.86$95.30$176.57$476.49
% of 52W HighCurrent price vs 52-week peak+52.1%+85.2%+82.8%+86.4%
RSI (14)Momentum oscillator 0–10054.052.646.844.9
Avg Volume (50D)Average daily shares traded2.9M5.8M5.8M631K
Evenly matched — ABBV and REGN each lead in 1 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: GILD as "Buy", ABBV as "Buy", REGN as "Buy". Consensus price targets imply 26.6% upside for ABBV (target: $257) vs 20.8% for GILD (target: $162). For income investors, ABBV offers the higher dividend yield at 3.24% vs REGN's 0.48%.

MetricCOCP logoCOCPCocrystal Pharma,…GILD logoGILDGilead Sciences, …ABBV logoABBVAbbVie Inc.REGN logoREGNRegeneron Pharmac…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$161.88$256.64$865.68
# AnalystsCovering analysts584148
Dividend YieldAnnual dividend ÷ price+2.4%+3.2%+0.5%
Dividend StreakConsecutive years of raises11131
Dividend / ShareAnnual DPS$3.19$6.57$3.41
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.2%+0.3%+5.4%
ABBV leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

GILD leads in 2 of 6 categories (Income & Cash Flow, Total Returns). ABBV leads in 1 (Analyst Outlook). 3 tied.

Best OverallGilead Sciences, Inc. (GILD)Leads 2 of 6 categories
Loading custom metrics...

COCP vs GILD vs ABBV vs REGN: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is COCP or GILD or ABBV or REGN a better buy right now?

For growth investors, AbbVie Inc.

(ABBV) is the stronger pick with 8. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate Gilead Sciences, Inc. (GILD) a "Buy" — based on 58 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — COCP or GILD or ABBV or REGN?

On trailing P/E, Regeneron Pharmaceuticals, Inc.

(REGN) is the cheapest at 17. 1x versus AbbVie Inc. at 85. 5x. On forward P/E, AbbVie Inc. is actually cheaper at 14. 3x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — COCP or GILD or ABBV or REGN?

Over the past 5 years, Gilead Sciences, Inc.

(GILD) delivered a total return of +124. 2%, compared to -91. 2% for Cocrystal Pharma, Inc. (COCP). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus COCP's -99. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — COCP or GILD or ABBV or REGN?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 34β versus Cocrystal Pharma, Inc. 's 1. 36β — meaning COCP is approximately 303% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 109% for Gilead Sciences, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — COCP or GILD or ABBV or REGN?

By revenue growth (latest reported year), AbbVie Inc.

(ABBV) is pulling ahead at 8. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Gilead Sciences, Inc. grew EPS 1684% year-over-year, compared to -0. 8% for AbbVie Inc.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — COCP or GILD or ABBV or REGN?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus 0. 0% for Cocrystal Pharma, Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: GILD leads at 40. 1% versus 0. 0% for COCP. At the gross margin level — before operating expenses — GILD leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is COCP or GILD or ABBV or REGN more undervalued right now?

On forward earnings alone, AbbVie Inc.

(ABBV) trades at 14. 3x forward P/E versus 15. 7x for Gilead Sciences, Inc. — 1. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ABBV: 26. 6% to $256. 64.

08

Which pays a better dividend — COCP or GILD or ABBV or REGN?

In this comparison, ABBV (3.

2% yield), GILD (2. 4% yield), REGN (0. 5% yield) pay a dividend. COCP does not pay a meaningful dividend and should not be held primarily for income.

09

Is COCP or GILD or ABBV or REGN better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, COCP: -99. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between COCP and GILD and ABBV and REGN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: COCP is a small-cap quality compounder stock; GILD is a mid-cap quality compounder stock; ABBV is a large-cap income-oriented stock; REGN is a mid-cap deep-value stock. GILD, ABBV pay a dividend while COCP, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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COCP

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  • Net Margin > 18%
  • Dividend Yield > 0.9%
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ABBV

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  • Market Cap > $100B
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REGN

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 9%
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