Biotechnology
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Side-by-side financial analysisStock Comparison
CRDF vs LLY vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Beverages - Non-Alcoholic
CRDF vs LLY vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Beverages - Non-Alcoholic |
| Market Cap | $109M | $1.10T | $355.22B |
| Revenue (TTM) | $525K | $72.25B | $49.28B |
| Net Income (TTM) | $-45M | $25.27B | $13.70B |
| Gross Margin | -21.5% | 83.5% | 61.7% |
| Operating Margin | -90.3% | 45.9% | 29.3% |
| Forward P/E | — | 30.9x | 25.2x |
| Total Debt | $832K | $42.50B | $45.49B |
| Cash & Equiv. | $17M | $7.16B | $10.27B |
CRDF vs LLY vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | Jun 26 | Return |
|---|---|---|---|
| Cardiff Oncology, I… (CRDF) | 100 | 30.7 | -69.3% |
| Eli Lilly and Compa… (LLY) | 100 | 690.1 | +590.1% |
| The Coca-Cola Compa… (KO) | 100 | 184.9 | +84.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CRDF vs LLY vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CRDF is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 2.30, Low D/E 1.8%, current ratio 3.67x
LLY carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 11 yrs, beta 0.53, yield 0.5%
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 15.2% 10Y total return vs KO's 120.9%
KO is the clearest fit if your priority is value and dividends.
- Better valuation composite
- 2.5% yield, 56-year raise streak, vs LLY's 0.5%, (1 stock pays no dividend)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs CRDF's -13.2% | |
| Value | Better valuation composite | |
| Quality / Margins | 35.0% margin vs CRDF's -85.3% | |
| Stability / Safety | Beta 0.53 vs CRDF's 2.30 | |
| Dividends | 2.5% yield, 56-year raise streak, vs LLY's 0.5%, (1 stock pays no dividend) | |
| Momentum (1Y) | +44.4% vs CRDF's -58.9% | |
| Efficiency (ROA) | 22.7% ROA vs CRDF's -71.5%, ROIC 41.8% vs -118.9% |
CRDF vs LLY vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
CRDF vs LLY vs KO — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY is the larger business by revenue, generating $72.2B annually — 137618.1x CRDF's $525,000. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to CRDF's -85.3%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $525,000 | $72.2B | $49.3B |
| EBITDAEarnings before interest/tax | -$46M | $34.7B | $15.5B |
| Net IncomeAfter-tax profit | -$45M | $25.3B | $13.7B |
| Free Cash FlowCash after capex | -$37M | $13.6B | $12.6B |
| Gross MarginGross profit ÷ Revenue | -21.5% | +83.5% | +61.7% |
| Operating MarginEBIT ÷ Revenue | -90.3% | +45.9% | +29.3% |
| Net MarginNet income ÷ Revenue | -85.3% | +35.0% | +27.8% |
| FCF MarginFCF ÷ Revenue | -71.4% | +18.8% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | -62.4% | +55.5% | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +35.7% | +169.9% | +18.2% |
Valuation Metrics
KO leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 27.1x trailing earnings, KO trades at a 46% valuation discount to LLY's 50.6x P/E. Adjusting for growth (PEG ratio), LLY offers better value at 1.76x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $109M | $1.10T | $355.2B |
| Enterprise ValueMkt cap + debt − cash | $92M | $1.13T | $390.4B |
| Trailing P/EPrice ÷ TTM EPS | -2.30x | 50.59x | 27.15x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 30.95x | 25.24x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.76x | 2.43x |
| EV / EBITDAEnterprise value multiple | — | 36.22x | 26.36x |
| Price / SalesMarket cap ÷ Revenue | 183.32x | 16.83x | 7.41x |
| Price / BookPrice ÷ Book value/share | 2.34x | 39.29x | 10.39x |
| Price / FCFMarket cap ÷ FCF | — | 122.26x | 67.07x |
Profitability & Efficiency
LLY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-96 for CRDF. CRDF carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to LLY's 1.60x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs CRDF's 3/9, reflecting strong financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | -95.5% | +101.2% | +41.1% |
| ROA (TTM)Return on assets | -71.5% | +22.7% | +13.1% |
| ROICReturn on invested capital | -118.9% | +41.8% | +15.8% |
| ROCEReturn on capital employed | -75.8% | +46.6% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 8 | 7 |
| Debt / EquityFinancial leverage | 0.02x | 1.60x | 1.33x |
| Net DebtTotal debt minus cash | -$17M | $35.3B | $35.2B |
| Cash & Equiv.Liquid assets | $17M | $7.2B | $10.3B |
| Total DebtShort + long-term debt | $832,000 | $42.5B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | — | 35.68x | 10.70x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $52,914 today (with dividends reinvested), compared to $2,018 for CRDF. Over the past 12 months, LLY leads with a +44.4% total return vs CRDF's -58.9%. The 3-year compound annual growth rate (CAGR) favors LLY at 38.3% vs CRDF's -0.6% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | -40.2% | +7.8% | +20.2% |
| 1-Year ReturnPast 12 months | -58.9% | +44.4% | +17.4% |
| 3-Year ReturnCumulative with dividends | -1.9% | +164.5% | +46.9% |
| 5-Year ReturnCumulative with dividends | -79.8% | +429.1% | +63.6% |
| 10-Year ReturnCumulative with dividends | -99.5% | +1522.5% | +120.9% |
| CAGR (3Y)Annualised 3-year return | -0.6% | +38.3% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.15 beta — it tends to amplify market swings less than CRDF's 2.30 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.2% from its 52-week high vs CRDF's 34.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.23x | 0.53x | -0.20x |
| 52-Week HighHighest price in past year | $4.56 | $1182.73 | $84.04 |
| 52-Week LowLowest price in past year | $1.36 | $623.78 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +34.9% | +98.2% | +98.2% |
| RSI (14)Momentum oscillator 0–100 | 42.1 | 66.8 | 65.7 |
| Avg Volume (50D)Average daily shares traded | 1.1M | 2.6M | 12.6M |
Analyst Outlook
KO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: CRDF as "Buy", LLY as "Buy", KO as "Buy". Consensus price targets imply 25.8% upside for CRDF (target: $2) vs 4.6% for KO (target: $86). For income investors, KO offers the higher dividend yield at 2.47% vs LLY's 0.52%.
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $2.00 | $1268.94 | $86.29 |
| # AnalystsCovering analysts | 14 | 45 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% | +2.5% |
| Dividend StreakConsecutive years of raises | 1 | 11 | 56 |
| Dividend / ShareAnnual DPS | — | $6.00 | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | +0.2% |
LLY leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). KO leads in 3 (Valuation Metrics, Risk & Volatility).
CRDF vs LLY vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is CRDF or LLY or KO a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus -13. 2% for Cardiff Oncology, Inc. (CRDF). The Coca-Cola Company (KO) offers the better valuation at 27. 1x trailing P/E (25. 2x forward), making it the more compelling value choice. Analysts rate Cardiff Oncology, Inc. (CRDF) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — CRDF or LLY or KO?
On trailing P/E, The Coca-Cola Company (KO) is the cheapest at 27.
1x versus Eli Lilly and Company at 50. 6x. On forward P/E, The Coca-Cola Company is actually cheaper at 25. 2x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Eli Lilly and Company wins at 1. 07x versus The Coca-Cola Company's 2. 26x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — CRDF or LLY or KO?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +429.
1%, compared to -79. 8% for Cardiff Oncology, Inc. (CRDF). Over 10 years, the gap is even starker: LLY returned +1485% versus CRDF's -99. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — CRDF or LLY or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Cardiff Oncology, Inc. 's 2. 23β — meaning CRDF is approximately -1214% more volatile than KO relative to the S&P 500. On balance sheet safety, Cardiff Oncology, Inc. (CRDF) carries a lower debt/equity ratio of 2% versus 160% for Eli Lilly and Company — giving it more financial flexibility in a downturn.
05Which is growing faster — CRDF or LLY or KO?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus -13. 2% for Cardiff Oncology, Inc. (CRDF). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to 23. 6% for The Coca-Cola Company. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — CRDF or LLY or KO?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus -77. 3% for Cardiff Oncology, Inc. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus -82. 6% for CRDF. At the gross margin level — before operating expenses — CRDF leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is CRDF or LLY or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Eli Lilly and Company (LLY) is the more undervalued stock at a PEG of 1. 07x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, The Coca-Cola Company (KO) trades at 25. 2x forward P/E versus 30. 9x for Eli Lilly and Company — 5. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CRDF: 25. 8% to $2. 00.
08Which pays a better dividend — CRDF or LLY or KO?
In this comparison, KO (2.
5% yield), LLY (0. 5% yield) pay a dividend. CRDF does not pay a meaningful dividend and should not be held primarily for income.
09Is CRDF or LLY or KO better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
53), 0. 5% yield, +1485% 10Y return). Cardiff Oncology, Inc. (CRDF) carries a higher beta of 2. 23 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LLY: +1485%, CRDF: -99. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between CRDF and LLY and KO?
These companies operate in different sectors (CRDF (Healthcare) and LLY (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: CRDF is a small-cap quality compounder stock; LLY is a mega-cap high-growth stock; KO is a large-cap quality compounder stock. LLY, KO pay a dividend while CRDF does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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