Biotechnology
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CRVS vs ALEC vs IMVT vs RCUS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
CRVS vs ALEC vs IMVT vs RCUS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1.23B | $269M | $5.53B | $2.50B |
| Revenue (TTM) | $0.00 | $21M | $0.00 | $236M |
| Net Income (TTM) | $-44M | $-143M | $-464M | $-369M |
| Gross Margin | — | — | — | 90.7% |
| Operating Margin | — | -7.4% | — | -168.6% |
| Total Debt | $937K | $36M | $98K | $99M |
| Cash & Equiv. | $5M | $66M | $714M | $222M |
CRVS vs ALEC vs IMVT vs RCUS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Corvus Pharmaceutic… (CRVS) | 100 | 422.9 | +322.9% |
| Alector, Inc. (ALEC) | 100 | 7.5 | -92.5% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| Arcus Biosciences, … (RCUS) | 100 | 79.1 | -20.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CRVS vs ALEC vs IMVT vs RCUS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CRVS carries the broadest edge in this set and is the clearest fit for quality and momentum.
- 3.5% margin vs ALEC's -6.8%
- +355.9% vs IMVT's +96.1%
ALEC lags the leaders in this set but could rank higher in a more targeted comparison.
IMVT is the clearest fit if your priority is income & stability and long-term compounding.
- beta 1.37
- 173.6% 10Y total return vs CRVS's 17.1%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
RCUS is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth -4.3%, EPS growth -4.8%, 3Y rev CAGR 30.2%
- -4.3% revenue growth vs ALEC's -79.1%
- -35.3% ROA vs ALEC's -48.7%, ROIC -64.1% vs -170.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | -4.3% revenue growth vs ALEC's -79.1% | |
| Quality / Margins | 3.5% margin vs ALEC's -6.8% | |
| Stability / Safety | Beta 1.37 vs ALEC's 2.47, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +355.9% vs IMVT's +96.1% | |
| Efficiency (ROA) | -35.3% ROA vs ALEC's -48.7%, ROIC -64.1% vs -170.3% |
CRVS vs ALEC vs IMVT vs RCUS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
CRVS vs ALEC vs IMVT vs RCUS — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
RCUS leads in 3 of 6 categories
CRVS leads 1 • IMVT leads 1 • ALEC leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
RCUS leads this category, winning 4 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. Profitability is closely matched — net margins range from -156.4% (RCUS) to -6.8% (ALEC). On growth, RCUS holds the edge at -39.3% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $21M | $0 | $236M |
| EBITDAEarnings before interest/tax | -$48M | -$156M | -$487M | -$391M |
| Net IncomeAfter-tax profit | -$44M | -$143M | -$464M | -$369M |
| Free Cash FlowCash after capex | -$35M | -$184M | -$423M | -$489M |
| Gross MarginGross profit ÷ Revenue | — | — | — | +90.7% |
| Operating MarginEBIT ÷ Revenue | — | -7.4% | — | -168.6% |
| Net MarginNet income ÷ Revenue | — | -6.8% | — | -156.4% |
| FCF MarginFCF ÷ Revenue | — | -8.7% | — | -2.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -88.5% | — | -39.3% |
| EPS Growth (YoY)Latest quarter vs prior year | -15.4% | -15.1% | +19.7% | +10.5% |
Valuation Metrics
RCUS leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.2B | $269M | $5.5B | $2.5B |
| Enterprise ValueMkt cap + debt − cash | $1.2B | $240M | $4.8B | $2.4B |
| Trailing P/EPrice ÷ TTM EPS | -27.53x | -1.76x | -9.97x | -7.54x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 12.80x | — | 10.11x |
| Price / BookPrice ÷ Book value/share | 19.01x | 8.20x | 5.83x | 4.22x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
RCUS leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
CRVS delivers a -38.9% return on equity — every $100 of shareholder capital generates $-39 in annual profit, vs $-5 for ALEC. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALEC's 1.18x. On the Piotroski fundamental quality scale (0–9), CRVS scores 3/9 vs RCUS's 0/9, reflecting mixed financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -38.9% | -4.7% | -47.1% | -69.0% |
| ROA (TTM)Return on assets | -35.7% | -48.7% | -44.1% | -35.3% |
| ROICReturn on invested capital | -78.1% | -170.3% | — | -64.1% |
| ROCEReturn on capital employed | -90.2% | -55.0% | -66.1% | -42.1% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 1 | 2 | 0 |
| Debt / EquityFinancial leverage | 0.02x | 1.18x | 0.00x | 0.16x |
| Net DebtTotal debt minus cash | -$4M | -$30M | -$714M | -$123M |
| Cash & Equiv.Liquid assets | $5M | $66M | $714M | $222M |
| Total DebtShort + long-term debt | $937,000 | $36M | $98,000 | $99M |
| Interest CoverageEBIT ÷ Interest expense | -18.29x | — | — | -13.38x |
Total Returns (Dividends Reinvested)
CRVS leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in CRVS five years ago would be worth $50,137 today (with dividends reinvested), compared to $1,492 for ALEC. Over the past 12 months, CRVS leads with a +355.9% total return vs IMVT's +96.1%. The 3-year compound annual growth rate (CAGR) favors CRVS at 123.9% vs ALEC's -32.5% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +99.3% | +59.5% | +5.1% | +6.5% |
| 1-Year ReturnPast 12 months | +355.9% | +139.2% | +96.1% | +209.6% |
| 3-Year ReturnCumulative with dividends | +1022.3% | -69.2% | +40.9% | +24.9% |
| 5-Year ReturnCumulative with dividends | +401.4% | -85.1% | +62.4% | -18.6% |
| 10-Year ReturnCumulative with dividends | +17.1% | -86.4% | +173.6% | +45.9% |
| CAGR (3Y)Annualised 3-year return | +123.9% | -32.5% | +12.1% | +7.7% |
Risk & Volatility
IMVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than ALEC's 2.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs CRVS's 54.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.63x | 2.47x | 1.37x | 1.95x |
| 52-Week HighHighest price in past year | $26.95 | $3.40 | $30.09 | $28.72 |
| 52-Week LowLowest price in past year | $3.17 | $0.97 | $13.36 | $7.06 |
| % of 52W HighCurrent price vs 52-week peak | +54.1% | +71.8% | +90.5% | +86.3% |
| RSI (14)Momentum oscillator 0–100 | 49.2 | 59.1 | 60.2 | 60.5 |
| Avg Volume (50D)Average daily shares traded | 1.2M | 684K | 1.4M | 1.2M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: CRVS as "Buy", ALEC as "Buy", IMVT as "Buy", RCUS as "Buy". Consensus price targets imply 127.3% upside for CRVS (target: $33) vs 21.0% for RCUS (target: $30).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $33.17 | $3.50 | $45.50 | $30.00 |
| # AnalystsCovering analysts | 13 | 14 | 23 | 18 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
RCUS leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CRVS leads in 1 (Total Returns).
CRVS vs ALEC vs IMVT vs RCUS: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is CRVS or ALEC or IMVT or RCUS a better buy right now?
For growth investors, Arcus Biosciences, Inc.
(RCUS) is the stronger pick with -4. 3% revenue growth year-over-year, versus -79. 1% for Alector, Inc. (ALEC). Analysts rate Corvus Pharmaceuticals, Inc. (CRVS) a "Buy" — based on 13 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CRVS or ALEC or IMVT or RCUS?
Over the past 5 years, Corvus Pharmaceuticals, Inc.
(CRVS) delivered a total return of +401. 4%, compared to -85. 1% for Alector, Inc. (ALEC). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus ALEC's -86. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CRVS or ALEC or IMVT or RCUS?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus Alector, Inc. 's 2. 47β — meaning ALEC is approximately 80% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 118% for Alector, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CRVS or ALEC or IMVT or RCUS?
By revenue growth (latest reported year), Arcus Biosciences, Inc.
(RCUS) is pulling ahead at -4. 3% versus -79. 1% for Alector, Inc. (ALEC). On earnings-per-share growth, the picture is similar: Corvus Pharmaceuticals, Inc. grew EPS 48. 0% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CRVS or ALEC or IMVT or RCUS?
Corvus Pharmaceuticals, Inc.
(CRVS) is the more profitable company, earning 0. 0% net margin versus -679. 2% for Alector, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CRVS leads at 0. 0% versus -741. 3% for ALEC. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — CRVS or ALEC or IMVT or RCUS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is CRVS or ALEC or IMVT or RCUS better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Alector, Inc. (ALEC) carries a higher beta of 2. 47 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, ALEC: -86. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between CRVS and ALEC and IMVT and RCUS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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