Biotechnology
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CTXR vs ETON vs PRGO vs TLRY
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
CTXR vs ETON vs PRGO vs TLRY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
| Market Cap | $12M | $839M | $1.61B | $660M |
| Revenue (TTM) | $0.00 | $80M | $4.18B | $1.17B |
| Net Income (TTM) | $-37M | $-5M | $-1.82B | $-2.95B |
| Gross Margin | — | 53.5% | 34.2% | 28.0% |
| Operating Margin | — | -1.1% | -4.1% | -266.0% |
| Forward P/E | — | 37.4x | 5.6x | — |
| Total Debt | $2M | $9M | $3.97B | $451M |
| Cash & Equiv. | $4M | $26M | $532M | $304M |
CTXR vs ETON vs PRGO vs TLRY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Citius Pharmaceutic… (CTXR) | 100 | 3.0 | -97.0% |
| Eton Pharmaceutical… (ETON) | 100 | 674.3 | +574.3% |
| Perrigo Company plc (PRGO) | 100 | 21.4 | -78.6% |
| Tilray Brands, Inc. (TLRY) | 100 | 57.5 | -42.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CTXR vs ETON vs PRGO vs TLRY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CTXR is the clearest fit if your priority is quality.
- -0.1% margin vs TLRY's -252.6%
ETON carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 104.9%, EPS growth -13.3%, 3Y rev CAGR 55.5%
- 396.3% 10Y total return vs TLRY's -74.7%
- Lower volatility, beta 0.66, Low D/E 35.4%, current ratio 1.57x
- 104.9% revenue growth vs CTXR's -100.0%
PRGO is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 10 yrs, beta 1.18, yield 9.8%
- Beta 1.18, yield 9.8%, current ratio 2.76x
- Better valuation composite
- 9.8% yield; 10-year raise streak; the other 3 pay no meaningful dividend
TLRY is the clearest fit if your priority is momentum.
- +12.1% vs PRGO's -51.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 104.9% revenue growth vs CTXR's -100.0% | |
| Value | Better valuation composite | |
| Quality / Margins | -0.1% margin vs TLRY's -252.6% | |
| Stability / Safety | Beta 0.66 vs CTXR's 2.76 | |
| Dividends | 9.8% yield; 10-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +12.1% vs PRGO's -51.2% | |
| Efficiency (ROA) | -4.8% ROA vs TLRY's -100.6%, ROIC -2.6% vs -66.2% |
CTXR vs ETON vs PRGO vs TLRY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
CTXR vs ETON vs PRGO vs TLRY — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ETON leads in 4 of 6 categories
PRGO leads 2 • CTXR leads 0 • TLRY leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
ETON leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PRGO and CTXR operate at a comparable scale, with $4.2B and $0 in trailing revenue. Profitability is closely matched — net margins range from -5.8% (ETON) to -2.5% (TLRY). On growth, ETON holds the edge at +82.7% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $80M | $4.2B | $1.2B |
| EBITDAEarnings before interest/tax | -$38M | $2M | $58M | -$3.0B |
| Net IncomeAfter-tax profit | -$37M | -$5M | -$1.8B | -$2.9B |
| Free Cash FlowCash after capex | -$27M | -$333,000 | $108M | -$94M |
| Gross MarginGross profit ÷ Revenue | — | +53.5% | +34.2% | +28.0% |
| Operating MarginEBIT ÷ Revenue | — | -1.1% | -4.1% | -2.7% |
| Net MarginNet income ÷ Revenue | — | -5.8% | -43.5% | -2.5% |
| FCF MarginFCF ÷ Revenue | — | -0.4% | +2.6% | -8.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | +82.7% | -7.2% | +3.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +74.1% | +3.4% | -56.4% | +70.7% |
Valuation Metrics
PRGO leads this category, winning 3 of 5 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $12M | $839M | $1.6B | $660M |
| Enterprise ValueMkt cap + debt − cash | $9M | $822M | $5.1B | $806M |
| Trailing P/EPrice ÷ TTM EPS | -0.19x | -182.47x | -1.14x | -0.17x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 37.37x | 5.56x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 7.42x | — |
| Price / SalesMarket cap ÷ Revenue | — | 10.49x | 0.38x | 0.59x |
| Price / BookPrice ÷ Book value/share | 0.09x | 31.91x | 0.55x | 0.25x |
| Price / FCFMarket cap ÷ FCF | — | 82.33x | 11.12x | — |
Profitability & Efficiency
ETON leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ETON delivers a -18.8% return on equity — every $100 of shareholder capital generates $-19 in annual profit, vs $-137 for TLRY. CTXR carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), ETON scores 5/9 vs TLRY's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -48.3% | -18.8% | -50.7% | -136.5% |
| ROA (TTM)Return on assets | -28.6% | -4.8% | -19.8% | -100.6% |
| ROICReturn on invested capital | -39.5% | -2.6% | +3.7% | -66.2% |
| ROCEReturn on capital employed | -46.2% | -1.5% | +4.3% | -78.1% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.02x | 0.35x | 1.35x | 0.22x |
| Net DebtTotal debt minus cash | -$3M | -$17M | $3.4B | $147M |
| Cash & Equiv.Liquid assets | $4M | $26M | $532M | $304M |
| Total DebtShort + long-term debt | $2M | $9M | $4.0B | $451M |
| Interest CoverageEBIT ÷ Interest expense | -143.54x | -1.07x | -7.20x | -89.43x |
Total Returns (Dividends Reinvested)
ETON leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ETON five years ago would be worth $39,216 today (with dividends reinvested), compared to $121 for CTXR. Over the past 12 months, TLRY leads with a +1209.3% total return vs PRGO's -51.2%. The 3-year compound annual growth rate (CAGR) favors ETON at 107.5% vs CTXR's -72.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -22.9% | +90.8% | -13.5% | -41.8% |
| 1-Year ReturnPast 12 months | -6.2% | +80.0% | -51.2% | +1209.3% |
| 3-Year ReturnCumulative with dividends | -98.0% | +793.9% | -58.1% | +103.6% |
| 5-Year ReturnCumulative with dividends | -98.8% | +292.2% | -60.1% | -65.0% |
| 10-Year ReturnCumulative with dividends | -99.9% | +396.3% | -77.7% | -74.7% |
| CAGR (3Y)Annualised 3-year return | -72.7% | +107.5% | -25.2% | +26.7% |
Risk & Volatility
ETON leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ETON is the less volatile stock with a 0.66 beta — it tends to amplify market swings less than CTXR's 2.76 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ETON currently trades 96.0% from its 52-week high vs CTXR's 26.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.76x | 0.66x | 1.18x | 2.03x |
| 52-Week HighHighest price in past year | $2.48 | $32.30 | $28.44 | $15.70 |
| 52-Week LowLowest price in past year | $0.57 | $13.09 | $9.23 | $0.35 |
| % of 52W HighCurrent price vs 52-week peak | +26.4% | +96.0% | +41.2% | +36.1% |
| RSI (14)Momentum oscillator 0–100 | 41.1 | 71.7 | 60.9 | 37.9 |
| Avg Volume (50D)Average daily shares traded | 746K | 392K | 3.4M | 4.7M |
Analyst Outlook
PRGO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ETON as "Buy", PRGO as "Hold", TLRY as "Hold". Consensus price targets imply 76.7% upside for TLRY (target: $10) vs -19.4% for ETON (target: $25). PRGO is the only dividend payer here at 9.81% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Hold | Hold |
| Price TargetConsensus 12-month target | — | $25.00 | $20.00 | $10.00 |
| # AnalystsCovering analysts | — | 6 | 36 | 20 |
| Dividend YieldAnnual dividend ÷ price | — | — | +9.8% | — |
| Dividend StreakConsecutive years of raises | — | 1 | 10 | — |
| Dividend / ShareAnnual DPS | — | — | $1.15 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
ETON leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRGO leads in 2 (Valuation Metrics, Analyst Outlook).
CTXR vs ETON vs PRGO vs TLRY: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is CTXR or ETON or PRGO or TLRY a better buy right now?
For growth investors, Eton Pharmaceuticals, Inc.
(ETON) is the stronger pick with 104. 9% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Analysts rate Eton Pharmaceuticals, Inc. (ETON) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CTXR or ETON or PRGO or TLRY?
Over the past 5 years, Eton Pharmaceuticals, Inc.
(ETON) delivered a total return of +292. 2%, compared to -98. 8% for Citius Pharmaceuticals, Inc. (CTXR). Over 10 years, the gap is even starker: ETON returned +396. 3% versus CTXR's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CTXR or ETON or PRGO or TLRY?
By beta (market sensitivity over 5 years), Eton Pharmaceuticals, Inc.
(ETON) is the lower-risk stock at 0. 66β versus Citius Pharmaceuticals, Inc. 's 2. 76β — meaning CTXR is approximately 321% more volatile than ETON relative to the S&P 500. On balance sheet safety, Citius Pharmaceuticals, Inc. (CTXR) carries a lower debt/equity ratio of 2% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
04Which is growing faster — CTXR or ETON or PRGO or TLRY?
By revenue growth (latest reported year), Eton Pharmaceuticals, Inc.
(ETON) is pulling ahead at 104. 9% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Citius Pharmaceuticals, Inc. grew EPS 43. 4% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, ETON leads at 55. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CTXR or ETON or PRGO or TLRY?
Citius Pharmaceuticals, Inc.
(CTXR) is the more profitable company, earning 0. 0% net margin versus -266. 3% for Tilray Brands, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PRGO leads at 8. 1% versus -277. 9% for TLRY. At the gross margin level — before operating expenses — ETON leads at 53. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is CTXR or ETON or PRGO or TLRY more undervalued right now?
On forward earnings alone, Perrigo Company plc (PRGO) trades at 5.
6x forward P/E versus 37. 4x for Eton Pharmaceuticals, Inc. — 31. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for TLRY: 76. 7% to $10. 00.
07Which pays a better dividend — CTXR or ETON or PRGO or TLRY?
In this comparison, PRGO (9.
8% yield) pays a dividend. CTXR, ETON, TLRY do not pay a meaningful dividend and should not be held primarily for income.
08Is CTXR or ETON or PRGO or TLRY better for a retirement portfolio?
For long-horizon retirement investors, Eton Pharmaceuticals, Inc.
(ETON) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), +396. 3% 10Y return). Citius Pharmaceuticals, Inc. (CTXR) carries a higher beta of 2. 76 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ETON: +396. 3%, CTXR: -99. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between CTXR and ETON and PRGO and TLRY?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CTXR is a small-cap quality compounder stock; ETON is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; TLRY is a small-cap quality compounder stock. PRGO pays a dividend while CTXR, ETON, TLRY do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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