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CYTK vs ACAD

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CYTK
Cytokinetics, Incorporated

Biotechnology

NASDAQ • US
Market Cap$9.15B
5Y Perf.+271.4%
ACAD
ACADIA Pharmaceuticals Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.86B
5Y Perf.-54.9%

CYTK vs ACAD — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CYTK logoCYTK
ACAD logoACAD
IndustryBiotechnologyBiotechnology
Market Cap$9.15B$3.86B
Revenue (TTM)$106M$1.10B
Net Income (TTM)$-830M$376M
Gross Margin90.3%91.5%
Operating Margin-6.1%7.4%
Forward P/E55.6x
Total Debt$1.28B$52M
Cash & Equiv.$882M$178M

CYTK vs ACADLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CYTK
ACAD
StockMay 20May 26Return
Cytokinetics, Incor… (CYTK)100371.4+271.4%
ACADIA Pharmaceutic… (ACAD)10045.1-54.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: CYTK vs ACAD

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CYTK leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and capital preservation and lower volatility. ACADIA Pharmaceuticals Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. As sector peers, any of these can serve as alternatives in the same allocation.
CYTK
Cytokinetics, Incorporated
The Income Pick

CYTK carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • beta 0.66
  • Rev growth 376.6%, EPS growth -24.3%, 3Y rev CAGR -2.4%
  • 8.2% 10Y total return vs ACAD's -22.9%
Best for: income & stability and growth exposure
ACAD
ACADIA Pharmaceuticals Inc.
The Quality Compounder

ACAD is the clearest fit if your priority is quality and efficiency.

  • 34.3% margin vs CYTK's -7.8%
  • 26.2% ROA vs CYTK's -61.9%, ROIC 10.0% vs -305.3%
Best for: quality and efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthCYTK logoCYTK376.6% revenue growth vs ACAD's 11.9%
Quality / MarginsACAD logoACAD34.3% margin vs CYTK's -7.8%
Stability / SafetyCYTK logoCYTKBeta 0.66 vs ACAD's 1.26
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)CYTK logoCYTK+124.8% vs ACAD's +52.4%
Efficiency (ROA)ACAD logoACAD26.2% ROA vs CYTK's -61.9%, ROIC 10.0% vs -305.3%

CYTK vs ACAD — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CYTKCytokinetics, Incorporated
FY 2025
Collaboration Revenues
100.0%$9M
ACADACADIA Pharmaceuticals Inc.
FY 2018
Product
100.0%$224M

CYTK vs ACAD — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCYTKLAGGINGACAD

Income & Cash Flow (Last 12 Months)

ACAD leads this category, winning 4 of 6 comparable metrics.

ACAD is the larger business by revenue, generating $1.1B annually — 10.4x CYTK's $106M. ACAD is the more profitable business, keeping 34.3% of every revenue dollar as net income compared to CYTK's -7.8%.

MetricCYTK logoCYTKCytokinetics, Inc…ACAD logoACADACADIA Pharmaceut…
RevenueTrailing 12 months$106M$1.1B
EBITDAEarnings before interest/tax-$633M$96M
Net IncomeAfter-tax profit-$830M$376M
Free Cash FlowCash after capex-$549M$212M
Gross MarginGross profit ÷ Revenue+90.3%+91.5%
Operating MarginEBIT ÷ Revenue-6.1%+7.4%
Net MarginNet income ÷ Revenue-7.8%+34.3%
FCF MarginFCF ÷ Revenue-5.2%+19.4%
Rev. Growth (YoY)Latest quarter vs prior year+11.3%+9.7%
EPS Growth (YoY)Latest quarter vs prior year-22.8%-81.8%
ACAD leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — CYTK and ACAD each lead in 1 of 2 comparable metrics.
MetricCYTK logoCYTKCytokinetics, Inc…ACAD logoACADACADIA Pharmaceut…
Market CapShares × price$9.1B$3.9B
Enterprise ValueMkt cap + debt − cash$9.6B$3.7B
Trailing P/EPrice ÷ TTM EPS-11.36x9.85x
Forward P/EPrice ÷ next-FY EPS est.55.62x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple26.91x
Price / SalesMarket cap ÷ Revenue103.93x3.61x
Price / BookPrice ÷ Book value/share3.15x
Price / FCFMarket cap ÷ FCF36.74x
Evenly matched — CYTK and ACAD each lead in 1 of 2 comparable metrics.

Profitability & Efficiency

ACAD leads this category, winning 6 of 6 comparable metrics.

On the Piotroski fundamental quality scale (0–9), ACAD scores 6/9 vs CYTK's 3/9, reflecting solid financial health.

MetricCYTK logoCYTKCytokinetics, Inc…ACAD logoACADACADIA Pharmaceut…
ROE (TTM)Return on equity+35.6%
ROA (TTM)Return on assets-61.9%+26.2%
ROICReturn on invested capital-3.1%+10.0%
ROCEReturn on capital employed-50.1%+10.1%
Piotroski ScoreFundamental quality 0–936
Debt / EquityFinancial leverage0.04x
Net DebtTotal debt minus cash$402M-$126M
Cash & Equiv.Liquid assets$882M$178M
Total DebtShort + long-term debt$1.3B$52M
Interest CoverageEBIT ÷ Interest expense-11.39x
ACAD leads this category, winning 6 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

CYTK leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in CYTK five years ago would be worth $30,660 today (with dividends reinvested), compared to $10,710 for ACAD. Over the past 12 months, CYTK leads with a +124.8% total return vs ACAD's +52.4%. The 3-year compound annual growth rate (CAGR) favors CYTK at 24.6% vs ACAD's 1.5% — a key indicator of consistent wealth creation.

MetricCYTK logoCYTKCytokinetics, Inc…ACAD logoACADACADIA Pharmaceut…
YTD ReturnYear-to-date+20.3%-13.7%
1-Year ReturnPast 12 months+124.8%+52.4%
3-Year ReturnCumulative with dividends+93.4%+4.7%
5-Year ReturnCumulative with dividends+206.6%+7.1%
10-Year ReturnCumulative with dividends+817.2%-22.9%
CAGR (3Y)Annualised 3-year return+24.6%+1.5%
CYTK leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

CYTK leads this category, winning 2 of 2 comparable metrics.

CYTK is the less volatile stock with a 0.66 beta — it tends to amplify market swings less than ACAD's 1.26 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CYTK currently trades 92.6% from its 52-week high vs ACAD's 81.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCYTK logoCYTKCytokinetics, Inc…ACAD logoACADACADIA Pharmaceut…
Beta (5Y)Sensitivity to S&P 5000.80x1.11x
52-Week HighHighest price in past year$80.20$27.81
52-Week LowLowest price in past year$29.31$14.45
% of 52W HighCurrent price vs 52-week peak+92.6%+81.1%
RSI (14)Momentum oscillator 0–10067.144.2
Avg Volume (50D)Average daily shares traded2.3M1.8M
CYTK leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates CYTK as "Buy" and ACAD as "Buy". Consensus price targets imply 54.1% upside for ACAD (target: $35) vs 34.1% for CYTK (target: $100).

MetricCYTK logoCYTKCytokinetics, Inc…ACAD logoACADACADIA Pharmaceut…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$99.62$34.78
# AnalystsCovering analysts3537
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ACAD leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CYTK leads in 2 (Total Returns, Risk & Volatility). 1 tied.

Best OverallCytokinetics, Incorporated (CYTK)Leads 2 of 6 categories
Loading custom metrics...

CYTK vs ACAD: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is CYTK or ACAD a better buy right now?

For growth investors, Cytokinetics, Incorporated (CYTK) is the stronger pick with 376.

6% revenue growth year-over-year, versus 11. 9% for ACADIA Pharmaceuticals Inc. (ACAD). ACADIA Pharmaceuticals Inc. (ACAD) offers the better valuation at 9. 9x trailing P/E (55. 6x forward), making it the more compelling value choice. Analysts rate Cytokinetics, Incorporated (CYTK) a "Buy" — based on 35 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CYTK or ACAD?

Over the past 5 years, Cytokinetics, Incorporated (CYTK) delivered a total return of +206.

6%, compared to +7. 1% for ACADIA Pharmaceuticals Inc. (ACAD). Over 10 years, the gap is even starker: CYTK returned +849. 5% versus ACAD's -23. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CYTK or ACAD?

By beta (market sensitivity over 5 years), Cytokinetics, Incorporated (CYTK) is the lower-risk stock at 0.

80β versus ACADIA Pharmaceuticals Inc. 's 1. 11β — meaning ACAD is approximately 40% more volatile than CYTK relative to the S&P 500.

04

Which is growing faster — CYTK or ACAD?

By revenue growth (latest reported year), Cytokinetics, Incorporated (CYTK) is pulling ahead at 376.

6% versus 11. 9% for ACADIA Pharmaceuticals Inc. (ACAD). On earnings-per-share growth, the picture is similar: ACADIA Pharmaceuticals Inc. grew EPS 68. 4% year-over-year, compared to -24. 3% for Cytokinetics, Incorporated. Over a 3-year CAGR, ACAD leads at 27. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CYTK or ACAD?

ACADIA Pharmaceuticals Inc.

(ACAD) is the more profitable company, earning 36. 5% net margin versus -891. 6% for Cytokinetics, Incorporated — meaning it keeps 36. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ACAD leads at 9. 8% versus -695. 4% for CYTK. At the gross margin level — before operating expenses — ACAD leads at 91. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CYTK or ACAD more undervalued right now?

Analyst consensus price targets imply the most upside for ACAD: 54.

1% to $34. 78.

07

Which pays a better dividend — CYTK or ACAD?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is CYTK or ACAD better for a retirement portfolio?

For long-horizon retirement investors, Cytokinetics, Incorporated (CYTK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

80), +849. 5% 10Y return). Both have compounded well over 10 years (CYTK: +849. 5%, ACAD: -23. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CYTK and ACAD?

Both stocks operate in the null sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CYTK is a small-cap high-growth stock; ACAD is a small-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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CYTK

High-Growth Disruptor

  • Market Cap > $100B
  • Revenue Growth > 562%
  • Gross Margin > 54%
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ACAD

Quality Mega-Cap Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 20%
Run This Screen
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Revenue Growth>
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