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CYTK vs RCUS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CYTK
Cytokinetics, Incorporated

Biotechnology

NASDAQ • US
Market Cap$9.15B
5Y Perf.+271.4%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.-19.1%

CYTK vs RCUS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CYTK logoCYTK
RCUS logoRCUS
IndustryBiotechnologyBiotechnology
Market Cap$9.15B$2.50B
Revenue (TTM)$106M$236M
Net Income (TTM)$-830M$-369M
Gross Margin90.3%90.7%
Operating Margin-6.1%-168.6%
Total Debt$1.28B$99M
Cash & Equiv.$882M$222M

CYTK vs RCUSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CYTK
RCUS
StockMay 20May 26Return
Cytokinetics, Incor… (CYTK)100371.4+271.4%
Arcus Biosciences, … (RCUS)10080.9-19.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: CYTK vs RCUS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: RCUS leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and recent price momentum and sentiment. Cytokinetics, Incorporated is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
CYTK
Cytokinetics, Incorporated
The Income Pick

CYTK is the clearest fit if your priority is income & stability and growth exposure.

  • beta 0.66
  • Rev growth 376.6%, EPS growth -24.3%, 3Y rev CAGR -2.4%
  • 8.2% 10Y total return vs RCUS's 45.9%
Best for: income & stability and growth exposure
RCUS
Arcus Biosciences, Inc.
The Quality Compounder

RCUS carries the broadest edge in this set and is the clearest fit for quality and momentum.

  • -156.4% margin vs CYTK's -7.8%
  • +209.6% vs CYTK's +124.8%
  • -35.3% ROA vs CYTK's -61.9%, ROIC -64.1% vs -305.3%
Best for: quality and momentum
See the full category breakdown
CategoryWinnerWhy
GrowthCYTK logoCYTK376.6% revenue growth vs RCUS's -4.3%
Quality / MarginsRCUS logoRCUS-156.4% margin vs CYTK's -7.8%
Stability / SafetyCYTK logoCYTKBeta 0.66 vs RCUS's 1.95
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)RCUS logoRCUS+209.6% vs CYTK's +124.8%
Efficiency (ROA)RCUS logoRCUS-35.3% ROA vs CYTK's -61.9%, ROIC -64.1% vs -305.3%

CYTK vs RCUS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CYTKCytokinetics, Incorporated
FY 2025
Collaboration Revenues
100.0%$9M
RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M

CYTK vs RCUS — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCYTKLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

RCUS leads this category, winning 5 of 6 comparable metrics.

RCUS is the larger business by revenue, generating $236M annually — 2.2x CYTK's $106M. Profitability is closely matched — net margins range from -156.4% (RCUS) to -7.8% (CYTK). On growth, CYTK holds the edge at +11.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCYTK logoCYTKCytokinetics, Inc…RCUS logoRCUSArcus Biosciences…
RevenueTrailing 12 months$106M$236M
EBITDAEarnings before interest/tax-$633M-$391M
Net IncomeAfter-tax profit-$830M-$369M
Free Cash FlowCash after capex-$549M-$489M
Gross MarginGross profit ÷ Revenue+90.3%+90.7%
Operating MarginEBIT ÷ Revenue-6.1%-168.6%
Net MarginNet income ÷ Revenue-7.8%-156.4%
FCF MarginFCF ÷ Revenue-5.2%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year+11.3%-39.3%
EPS Growth (YoY)Latest quarter vs prior year-22.8%+10.5%
RCUS leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — CYTK and RCUS each lead in 1 of 2 comparable metrics.
MetricCYTK logoCYTKCytokinetics, Inc…RCUS logoRCUSArcus Biosciences…
Market CapShares × price$9.1B$2.5B
Enterprise ValueMkt cap + debt − cash$9.6B$2.4B
Trailing P/EPrice ÷ TTM EPS-11.36x-7.54x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue103.93x10.11x
Price / BookPrice ÷ Book value/share4.22x
Price / FCFMarket cap ÷ FCF
Evenly matched — CYTK and RCUS each lead in 1 of 2 comparable metrics.

Profitability & Efficiency

RCUS leads this category, winning 5 of 7 comparable metrics.

On the Piotroski fundamental quality scale (0–9), CYTK scores 3/9 vs RCUS's 0/9, reflecting mixed financial health.

MetricCYTK logoCYTKCytokinetics, Inc…RCUS logoRCUSArcus Biosciences…
ROE (TTM)Return on equity-69.0%
ROA (TTM)Return on assets-61.9%-35.3%
ROICReturn on invested capital-3.1%-64.1%
ROCEReturn on capital employed-50.1%-42.1%
Piotroski ScoreFundamental quality 0–930
Debt / EquityFinancial leverage0.16x
Net DebtTotal debt minus cash$402M-$123M
Cash & Equiv.Liquid assets$882M$222M
Total DebtShort + long-term debt$1.3B$99M
Interest CoverageEBIT ÷ Interest expense-11.39x-13.38x
RCUS leads this category, winning 5 of 7 comparable metrics.

Total Returns (Dividends Reinvested)

CYTK leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in CYTK five years ago would be worth $30,660 today (with dividends reinvested), compared to $8,143 for RCUS. Over the past 12 months, RCUS leads with a +209.6% total return vs CYTK's +124.8%. The 3-year compound annual growth rate (CAGR) favors CYTK at 24.6% vs RCUS's 7.7% — a key indicator of consistent wealth creation.

MetricCYTK logoCYTKCytokinetics, Inc…RCUS logoRCUSArcus Biosciences…
YTD ReturnYear-to-date+20.3%+6.5%
1-Year ReturnPast 12 months+124.8%+209.6%
3-Year ReturnCumulative with dividends+93.4%+24.9%
5-Year ReturnCumulative with dividends+206.6%-18.6%
10-Year ReturnCumulative with dividends+817.2%+45.9%
CAGR (3Y)Annualised 3-year return+24.6%+7.7%
CYTK leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

CYTK leads this category, winning 2 of 2 comparable metrics.

CYTK is the less volatile stock with a 0.66 beta — it tends to amplify market swings less than RCUS's 1.95 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CYTK currently trades 92.6% from its 52-week high vs RCUS's 86.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCYTK logoCYTKCytokinetics, Inc…RCUS logoRCUSArcus Biosciences…
Beta (5Y)Sensitivity to S&P 5000.80x1.84x
52-Week HighHighest price in past year$80.20$28.72
52-Week LowLowest price in past year$29.31$7.06
% of 52W HighCurrent price vs 52-week peak+92.6%+86.3%
RSI (14)Momentum oscillator 0–10067.160.5
Avg Volume (50D)Average daily shares traded2.3M1.2M
CYTK leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates CYTK as "Buy" and RCUS as "Buy". Consensus price targets imply 34.1% upside for CYTK (target: $100) vs 21.0% for RCUS (target: $30).

MetricCYTK logoCYTKCytokinetics, Inc…RCUS logoRCUSArcus Biosciences…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$99.62$30.00
# AnalystsCovering analysts3518
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

RCUS leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CYTK leads in 2 (Total Returns, Risk & Volatility). 1 tied.

Best OverallCytokinetics, Incorporated (CYTK)Leads 2 of 6 categories
Loading custom metrics...

CYTK vs RCUS: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is CYTK or RCUS a better buy right now?

For growth investors, Cytokinetics, Incorporated (CYTK) is the stronger pick with 376.

6% revenue growth year-over-year, versus -4. 3% for Arcus Biosciences, Inc. (RCUS). Analysts rate Cytokinetics, Incorporated (CYTK) a "Buy" — based on 35 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CYTK or RCUS?

Over the past 5 years, Cytokinetics, Incorporated (CYTK) delivered a total return of +206.

6%, compared to -18. 6% for Arcus Biosciences, Inc. (RCUS). Over 10 years, the gap is even starker: CYTK returned +849. 5% versus RCUS's +49. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CYTK or RCUS?

By beta (market sensitivity over 5 years), Cytokinetics, Incorporated (CYTK) is the lower-risk stock at 0.

80β versus Arcus Biosciences, Inc. 's 1. 84β — meaning RCUS is approximately 131% more volatile than CYTK relative to the S&P 500.

04

Which is growing faster — CYTK or RCUS?

By revenue growth (latest reported year), Cytokinetics, Incorporated (CYTK) is pulling ahead at 376.

6% versus -4. 3% for Arcus Biosciences, Inc. (RCUS). On earnings-per-share growth, the picture is similar: Arcus Biosciences, Inc. grew EPS -4. 8% year-over-year, compared to -24. 3% for Cytokinetics, Incorporated. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CYTK or RCUS?

Arcus Biosciences, Inc.

(RCUS) is the more profitable company, earning -142. 9% net margin versus -891. 6% for Cytokinetics, Incorporated — meaning it keeps -142. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RCUS leads at -156. 3% versus -695. 4% for CYTK. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — CYTK or RCUS?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is CYTK or RCUS better for a retirement portfolio?

For long-horizon retirement investors, Cytokinetics, Incorporated (CYTK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

80), +849. 5% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 84 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CYTK: +849. 5%, RCUS: +49. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between CYTK and RCUS?

Both stocks operate in the null sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CYTK is a small-cap high-growth stock; RCUS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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CYTK

High-Growth Disruptor

  • Market Cap > $100B
  • Revenue Growth > 562%
  • Gross Margin > 54%
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RCUS

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 54%
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