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DNTH
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KO logo
KO
RARE logo
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BEAM logo
BEAM
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Stock Comparison

DNTH vs APLS vs KO vs RARE vs BEAM

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
DNTH
Dianthus Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.19B
5Y Perf.-36.4%
APLS
Apellis Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.25B
5Y Perf.+25.4%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.22B
5Y Perf.+84.7%
RARE
Ultragenyx Pharmaceutical Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2.36B
5Y Perf.-69.3%
BEAM
Beam Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.02B
5Y Perf.+5.0%

DNTH vs APLS vs KO vs RARE vs BEAM — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
DNTH logoDNTH
APLS logoAPLS
KO logoKO
RARE logoRARE
BEAM logoBEAM
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicBiotechnologyBiotechnology
Market Cap$3.19B$5.25B$355.22B$2.36B$3.02B
Revenue (TTM)$1M$1.03B$49.28B$669M$132M
Net Income (TTM)$-11M$133M$13.70B$-609M$-65M
Gross Margin94.3%89.4%61.7%83.6%-64.2%
Operating Margin-143.2%16.1%29.3%-83.9%-281.0%
Forward P/E227.9x25.2x
Total Debt$1M$486M$45.49B$1.28B$294M
Cash & Equiv.$51M$468M$10.27B$434M$295M

DNTH vs APLS vs KO vs RARE vs BEAMLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

DNTH
APLS
KO
RARE
BEAM
StockJun 20Jun 26Return
Dianthus Therapeuti… (DNTH)10063.6-36.4%
Apellis Pharmaceuti… (APLS)100125.4+25.4%
The Coca-Cola Compa… (KO)100184.7+84.7%
Ultragenyx Pharmace… (RARE)10030.7-69.3%
Beam Therapeutics I… (BEAM)100105.0+5.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: DNTH vs APLS vs KO vs RARE vs BEAM

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO leads in 3 of 7 categories (5-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Apellis Pharmaceuticals, Inc. is the stronger pick specifically for capital preservation and lower volatility and operational efficiency and capital deployment. DNTH and BEAM also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇KO emerged as the overall leader. Track its performance:
DNTH
Dianthus Therapeutics, Inc.
The Defensive Pick

DNTH ranks third and is worth considering specifically for sleep-well-at-night and defensive.

  • Lower volatility, beta 1.29, Low D/E 0.3%, current ratio 13.32x
  • Beta 1.29, current ratio 13.32x
  • +321.9% vs RARE's -36.1%
Best for: sleep-well-at-night and defensive
APLS
Apellis Pharmaceuticals, Inc.
The Growth Play

APLS is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 28.5%, EPS growth 111.3%, 3Y rev CAGR 137.0%
  • 192.4% 10Y total return vs KO's 120.9%
  • Beta 1.06 vs BEAM's 2.27
  • 13.2% ROA vs RARE's -45.8%, ROIC 12.3% vs -89.4%
Best for: growth exposure and long-term compounding
KO
The Coca-Cola Company
The Value Play

KO carries the broadest edge in this set and is the clearest fit for value and quality.

  • Better valuation composite
  • 27.8% margin vs DNTH's -8.5%
  • 2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Best for: value and quality
RARE
Ultragenyx Pharmaceutical Inc.
The Income Pick

RARE is the clearest fit if your priority is income & stability.

  • Dividend streak 1 yrs, beta 1.47
Best for: income & stability
BEAM
Beam Therapeutics Inc.
The Growth Leader

BEAM is the clearest fit if your priority is growth.

  • 120.0% revenue growth vs DNTH's -67.3%
Best for: growth
See the full category breakdown
CategoryWinnerWhy
GrowthBEAM logoBEAM120.0% revenue growth vs DNTH's -67.3%
ValueKO logoKOBetter valuation composite
Quality / MarginsKO logoKO27.8% margin vs DNTH's -8.5%
Stability / SafetyAPLS logoAPLSBeta 1.06 vs BEAM's 2.27
DividendsKO logoKO2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)DNTH logoDNTH+321.9% vs RARE's -36.1%
Efficiency (ROA)APLS logoAPLS13.2% ROA vs RARE's -45.8%, ROIC 12.3% vs -89.4%

DNTH vs APLS vs KO vs RARE vs BEAM — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
DNTHDianthus Therapeutics, Inc.
FY 2025
License
100.0%$2M
APLSApellis Pharmaceuticals, Inc.
FY 2025
Product
68.7%$689M
Licensing And Other Revenue
31.3%$314M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
RAREUltragenyx Pharmaceutical Inc.
FY 2025
Product
54.8%$369M
Royalty
45.2%$304M
BEAMBeam Therapeutics Inc.

Segment breakdown not available.

DNTH vs APLS vs KO vs RARE vs BEAM — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKOLAGGINGBEAM

Income & Cash Flow (Last 12 Months)

KO leads this category, winning 3 of 6 comparable metrics.

KO is the larger business by revenue, generating $49.3B annually — 36889.2x DNTH's $1M. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to DNTH's -8.5%. On growth, APLS holds the edge at +15.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricDNTH logoDNTHDianthus Therapeu…APLS logoAPLSApellis Pharmaceu…KO logoKOThe Coca-Cola Com…RARE logoRAREUltragenyx Pharma…BEAM logoBEAMBeam Therapeutics…
RevenueTrailing 12 months$1M$1.0B$49.3B$669M$132M
EBITDAEarnings before interest/tax-$191M$166M$15.5B-$536M-$355M
Net IncomeAfter-tax profit-$11M$133M$13.7B-$609M-$65M
Free Cash FlowCash after capex-$130M$38M$12.6B-$487M-$384M
Gross MarginGross profit ÷ Revenue+94.3%+89.4%+61.7%+83.6%-64.2%
Operating MarginEBIT ÷ Revenue-143.2%+16.1%+29.3%-83.9%-2.8%
Net MarginNet income ÷ Revenue-8.5%+13.0%+27.8%-91.0%-49.2%
FCF MarginFCF ÷ Revenue-97.7%+3.7%+25.5%-72.8%-2.9%
Rev. Growth (YoY)Latest quarter vs prior year-60.2%+15.1%+12.1%-2.4%-100.0%
EPS Growth (YoY)Latest quarter vs prior year-3.7%+100.0%+18.2%-17.2%+26.6%
KO leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — KO and BEAM each lead in 2 of 5 comparable metrics.

At 27.1x trailing earnings, KO trades at a 88% valuation discount to APLS's 227.9x P/E. On an enterprise value basis, KO's 26.4x EV/EBITDA is more attractive than APLS's 92.5x.

MetricDNTH logoDNTHDianthus Therapeu…APLS logoAPLSApellis Pharmaceu…KO logoKOThe Coca-Cola Com…RARE logoRAREUltragenyx Pharma…BEAM logoBEAMBeam Therapeutics…
Market CapShares × price$3.2B$5.3B$355.2B$2.4B$3.0B
Enterprise ValueMkt cap + debt − cash$3.1B$5.3B$390.4B$3.2B$3.0B
Trailing P/EPrice ÷ TTM EPS-18.20x227.94x27.15x-4.11x-36.31x
Forward P/EPrice ÷ next-FY EPS est.25.24x
PEG RatioP/E ÷ EPS growth rate2.43x
EV / EBITDAEnterprise value multiple92.50x26.36x
Price / SalesMarket cap ÷ Revenue1567.68x5.23x7.41x3.50x21.62x
Price / BookPrice ÷ Book value/share5.86x13.97x10.39x2.35x
Price / FCFMarket cap ÷ FCF116.69x67.07x
Evenly matched — KO and BEAM each lead in 2 of 5 comparable metrics.

Profitability & Efficiency

KO leads this category, winning 5 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-6 for RARE. DNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), APLS scores 7/9 vs DNTH's 2/9, reflecting strong financial health.

MetricDNTH logoDNTHDianthus Therapeu…APLS logoAPLSApellis Pharmaceu…KO logoKOThe Coca-Cola Com…RARE logoRAREUltragenyx Pharma…BEAM logoBEAMBeam Therapeutics…
ROE (TTM)Return on equity-1.8%+39.7%+41.1%-6.1%-5.9%
ROA (TTM)Return on assets-1.7%+13.2%+13.1%-45.8%-4.6%
ROICReturn on invested capital-34.4%+12.3%+15.8%-89.4%-31.1%
ROCEReturn on capital employed-41.6%+7.6%+17.3%-46.4%-33.3%
Piotroski ScoreFundamental quality 0–927744
Debt / EquityFinancial leverage0.00x1.31x1.33x0.24x
Net DebtTotal debt minus cash-$50M$19M$35.2B$842M-$1M
Cash & Equiv.Liquid assets$51M$468M$10.3B$434M$295M
Total DebtShort + long-term debt$1M$486M$45.5B$1.3B$294M
Interest CoverageEBIT ÷ Interest expense6.50x10.70x-14.49x1.08x
KO leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

DNTH leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in KO five years ago would be worth $16,364 today (with dividends reinvested), compared to $2,358 for RARE. Over the past 12 months, DNTH leads with a +321.9% total return vs RARE's -36.1%. The 3-year compound annual growth rate (CAGR) favors DNTH at 89.0% vs APLS's -23.2% — a key indicator of consistent wealth creation.

MetricDNTH logoDNTHDianthus Therapeu…APLS logoAPLSApellis Pharmaceu…KO logoKOThe Coca-Cola Com…RARE logoRAREUltragenyx Pharma…BEAM logoBEAMBeam Therapeutics…
YTD ReturnYear-to-date+92.7%+58.7%+20.2%+1.6%+8.4%
1-Year ReturnPast 12 months+321.9%+112.9%+17.4%-36.1%+64.4%
3-Year ReturnCumulative with dividends+574.8%-54.7%+46.9%-53.3%-10.8%
5-Year ReturnCumulative with dividends-58.7%-34.0%+63.6%-76.4%-66.9%
10-Year ReturnCumulative with dividends-67.1%+192.4%+120.9%-60.0%+56.9%
CAGR (3Y)Annualised 3-year return+89.0%-23.2%+13.7%-22.4%-3.7%
DNTH leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — APLS and KO each lead in 1 of 2 comparable metrics.

KO is the less volatile stock with a -0.15 beta — it tends to amplify market swings less than BEAM's 2.27 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. APLS currently trades 99.8% from its 52-week high vs RARE's 56.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricDNTH logoDNTHDianthus Therapeu…APLS logoAPLSApellis Pharmaceu…KO logoKOThe Coca-Cola Com…RARE logoRAREUltragenyx Pharma…BEAM logoBEAMBeam Therapeutics…
Beta (5Y)Sensitivity to S&P 5001.29x1.06x-0.15x1.47x2.27x
52-Week HighHighest price in past year$96.50$41.12$84.04$42.37$36.44
52-Week LowLowest price in past year$16.64$16.83$65.35$18.29$15.60
% of 52W HighCurrent price vs 52-week peak+79.2%+99.8%+98.2%+56.6%+80.7%
RSI (14)Momentum oscillator 0–10037.884.365.747.548.7
Avg Volume (50D)Average daily shares traded674K6.7M12.6M1.5M1.9M
Evenly matched — APLS and KO each lead in 1 of 2 comparable metrics.

Analyst Outlook

KO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: DNTH as "Buy", APLS as "Buy", KO as "Buy", RARE as "Buy", BEAM as "Buy". Consensus price targets imply 101.7% upside for RARE (target: $48) vs -18.6% for APLS (target: $33). KO is the only dividend payer here at 2.47% yield — a key consideration for income-focused portfolios.

MetricDNTH logoDNTHDianthus Therapeu…APLS logoAPLSApellis Pharmaceu…KO logoKOThe Coca-Cola Com…RARE logoRAREUltragenyx Pharma…BEAM logoBEAMBeam Therapeutics…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$111.91$33.40$86.29$48.36$48.00
# AnalystsCovering analysts1025483327
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises5610
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.2%0.0%0.0%
KO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

KO leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). DNTH leads in 1 (Total Returns). 2 tied.

Best OverallThe Coca-Cola Company (KO)Leads 3 of 6 categories
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DNTH vs APLS vs KO vs RARE vs BEAM: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is DNTH or APLS or KO or RARE or BEAM a better buy right now?

For growth investors, Beam Therapeutics Inc.

(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -67. 3% for Dianthus Therapeutics, Inc. (DNTH). The Coca-Cola Company (KO) offers the better valuation at 27. 1x trailing P/E (25. 2x forward), making it the more compelling value choice. Analysts rate Dianthus Therapeutics, Inc. (DNTH) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — DNTH or APLS or KO or RARE or BEAM?

On trailing P/E, The Coca-Cola Company (KO) is the cheapest at 27.

1x versus Apellis Pharmaceuticals, Inc. at 227. 9x.

03

Which is the better long-term investment — DNTH or APLS or KO or RARE or BEAM?

Over the past 5 years, The Coca-Cola Company (KO) delivered a total return of +63.

6%, compared to -76. 4% for Ultragenyx Pharmaceutical Inc. (RARE). Over 10 years, the gap is even starker: APLS returned +192. 4% versus DNTH's -67. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — DNTH or APLS or KO or RARE or BEAM?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

15β versus Beam Therapeutics Inc. 's 2. 27β — meaning BEAM is approximately -1638% more volatile than KO relative to the S&P 500. On balance sheet safety, Dianthus Therapeutics, Inc. (DNTH) carries a lower debt/equity ratio of 0% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.

05

Which is growing faster — DNTH or APLS or KO or RARE or BEAM?

By revenue growth (latest reported year), Beam Therapeutics Inc.

(BEAM) is pulling ahead at 120. 0% versus -67. 3% for Dianthus Therapeutics, Inc. (DNTH). On earnings-per-share growth, the picture is similar: Apellis Pharmaceuticals, Inc. grew EPS 111. 3% year-over-year, compared to -64. 7% for Dianthus Therapeutics, Inc.. Over a 3-year CAGR, APLS leads at 137. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — DNTH or APLS or KO or RARE or BEAM?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -79. 7% for Dianthus Therapeutics, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -87. 4% for DNTH. At the gross margin level — before operating expenses — DNTH leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is DNTH or APLS or KO or RARE or BEAM more undervalued right now?

Analyst consensus price targets imply the most upside for RARE: 101.

7% to $48. 36.

08

Which pays a better dividend — DNTH or APLS or KO or RARE or BEAM?

In this comparison, KO (2.

5% yield) pays a dividend. DNTH, APLS, RARE, BEAM do not pay a meaningful dividend and should not be held primarily for income.

09

Is DNTH or APLS or KO or RARE or BEAM better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

15), 2. 5% yield, +120. 9% 10Y return). Beam Therapeutics Inc. (BEAM) carries a higher beta of 2. 27 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +120. 9%, BEAM: +56. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between DNTH and APLS and KO and RARE and BEAM?

These companies operate in different sectors (DNTH (Healthcare) and APLS (Healthcare) and KO (Consumer Defensive) and RARE (Healthcare) and BEAM (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: DNTH is a small-cap quality compounder stock; APLS is a small-cap high-growth stock; KO is a large-cap quality compounder stock; RARE is a small-cap high-growth stock; BEAM is a small-cap high-growth stock. KO pays a dividend while DNTH, APLS, RARE, BEAM do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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