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RAREUltragenyx Pharmaceutical Inc.
$14.88$1.5B
Overview & Tools
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RARE logo

Ultragenyx Pharmaceutical Inc.

RARE
NASDAQ · Biotechnology
$14.88
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$1.47B
P/E-2.6x
52W High$39.89
Volume5.7M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Revenue Inflection Masks Negative Equity and Cash Burn

Ultragenyx is executing on a commercial inflection, with 2026Q2 revenue reaching $214.0M (+28.5% YoY) and gross margin expanding to 84.1%, yet the company remains deeply unprofitable with operating margin at -35.0% and a net loss of -$92.0M. The balance sheet ...

GrowthMixed
ProfitabilityWeak
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

RARE price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-107% Peers

P/E is 107% below peer median

03

Market leadership

RS 8 · Lag

Laggard (Underperforming 92% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Nov 4

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
RARE-36.95%
S&P 500 (^GSPC)+12.39%
1-Year Return
RARE-47.61%
S&P 500 (^GSPC)+15.77%
3-Year Return
RARE-59.42%
S&P 500 (^GSPC)+71.70%
5-Year Return
RARE-84.74%
S&P 500 (^GSPC)+67.06%

Growth & profitability

Annual revenue & EPS trend
Revenue
$673M+20.1% YoY
Net income
-$575M-1.0% YoY
Free cash flow
-$472M-11.9% YoY
Operating margin
-79.5%+16.2 pts YoY
ROIC (TTM)-89.4%
Avg ROIC 5Y-
ROE (TTM)-607.5%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
Revenue Beat Rate6/12 (50%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 4, 2026
-$0.90+26.2%
vs -$1.22
$214M+16.9%
vs $183M
Q2 2026
May 5, 2026
-$1.84-23.7%
vs -$1.49
$136M-14.0%
vs $158M
Q1 2026
Feb 12, 2026
-$1.29-7.5%
vs -$1.20
$207M+4.2%
vs $199M
Q4 2025
Nov 4, 2025
-$1.81-47.2%
vs -$1.23
$160M-19.9%
vs $200M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GlobeNewsWire·2d ago
ULTRA-RARE MCA CENTENAIRE, MONACO'S FIRST SUPERCAR, OFFERED AT BROAD ARROW'S 2026 ZOUTE CONCOURS AUCTION

Monte Carlo Automotive (MCA) Centenaire was the first road car with a carbon fibre monocoque chassis and is powered by a 5.2-litre V12 from the Lamborghini Countach 5000 QV | This example of Monaco's first supercar, created in partnership with Lamborghini, is the first of just five Centenaire models produced | Originally retained by the Lamborghini factory and displayed at Rétromobile 2007, the Centenaire is now eligible for many prestigious concours events | Offered for sale at Broad Arrow's Zoute Concours Auction on 9 October 2026 in collaboration with Zoute Grand Prix Car Week Monte Carlo Automotive (MCA) Centenaire was the first road car with a carbon fibre monocoque chassis and is powered by a 5.2-litre V12 from the Lamborghini Countach 5000 QV | This example of Monaco's first supercar, created in partnership with Lamborghini, is the first of just five Centenaire models produced | Originally retained by the Lamborghini factory and displayed at Rétromobile 2007, the Centenaire is now eligible for many prestigious concours events | Offered for sale at Broad Arrow's Zoute Concours Auction on 9 October 2026 in collaboration with Zoute Grand Prix Car Week

Zacks Investment Research·5d ago
RARE Stock Up 13% on FDA Approval of Sanfilippo Syndrome Gene Therapy

Ultragenyx jumps 13% after FDA approval of Fayuvi, the first approved treatment for Sanfilippo syndrome Type A, backed by durable clinical data.

Zacks Investment Research·5d ago
Ultragenyx (RARE) Surges 12.6%: Is This an Indication of Further Gains?

Ultragenyx (RARE) was a big mover last session on higher-than-average trading volume. The latest trend in earnings estimate revisions might help the stock continue moving higher in the near term.

Benzinga·5d ago
Abeona Stands to Collect Royalties After Ultragenyx's FDA Approval — Here's the Rest of the Week

Abeona Therapeutics Inc. (NASDAQ:ABEO) had a busy week that included a new treatment center activation, an FDA approval for a drug the company licensed away and multiple fresh analyst ratings.

Filtered for Ultragenyx Pharmaceutical Inc.More Headlines
04

Compare before deciding

Benchmark RARE against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Ultragenyx Pharmaceutical Inc. (RARE)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
RARE logoRAREUltragenyx Pharmaceutical Inc.Current
$14.88$1.47B-2.5520.13%-85.44%-607.51%—
BMRN logoBMRNBioMarin Pharmaceutical Inc.
$62.21$12.02B34.5612.87%2.14%1.18%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$18.95$2B-2.6615.58%-6.93%-9.96%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$43.93$7.3B-18.4633.87%-64.64%-110.84%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$25.43$4.35B11.1011.87%33.42%32.39%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—

Compare RARE vs Peers

Ultragenyx Pharmaceutical Inc. (RARE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs BMRN

Most directly comparable listed peer for RARE.

Scale Benchmark

vs MEDP

Larger-name benchmark to compare RARE against a more recognizable public peer.

Peer Set

Compare Top 5

vs BMRN, SRPT, IONS, ACAD

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

RARE SEC Filings & Documents

Ultragenyx Pharmaceutical Inc. (RARE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 19, 2026·SEC

Material company update

Aug 11, 2026·SEC

Material company update

Aug 4, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 18, 2026·SEC

FY 2025

Feb 19, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 5, 2026·SEC

FY 2026

May 6, 2026·SEC

FY 2025

Nov 5, 2025·SEC

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RARE Frequently Asked Questions

Ultragenyx Pharmaceutical Inc. (RARE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Ultragenyx Pharmaceutical Inc.'s revenue?

Ultragenyx Pharmaceutical Inc. (RARE) reported $716.9M in revenue for fiscal year 2025.

How fast is Ultragenyx Pharmaceutical Inc. growing?

Ultragenyx Pharmaceutical Inc. (RARE) grew revenue by 20.1% over the past year. This is strong growth.

Is RARE profitable?

Ultragenyx Pharmaceutical Inc. (RARE) reported a net loss of $586.4M for fiscal year 2025.

Dividend & Returns
What is RARE's return on equity?

Ultragenyx Pharmaceutical Inc. (RARE) has a return on equity (ROE) of -607.5%. Negative ROE indicates the company is unprofitable.

What is Ultragenyx Pharmaceutical Inc.'s free cash flow?

Ultragenyx Pharmaceutical Inc. (RARE) had negative free cash flow of $489.5M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in RARE back in 2011?

Total return calculator · dividends reinvested · 15+ years of data

See returns →