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DTIL vs DBVT vs SANA vs IMVT vs BEAM

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
DTIL
Precision BioSciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$96M
5Y Perf.-97.9%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-62.6%
SANA
Sana Biotechnology, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$918M
5Y Perf.-88.6%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+72.5%
BEAM
Beam Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.23B
5Y Perf.-64.7%

DTIL vs DBVT vs SANA vs IMVT vs BEAM — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
DTIL logoDTIL
DBVT logoDBVT
SANA logoSANA
IMVT logoIMVT
BEAM logoBEAM
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$96M$1712.35T$918M$5.53B$3.23B
Revenue (TTM)$45M$0.00$0.00$0.00$132M
Net Income (TTM)$-44M$-168M$-234M$-464M$-65M
Gross Margin97.0%-64.2%
Operating Margin-86.8%-281.0%
Total Debt$29M$22M$94M$98K$294M
Cash & Equiv.$111M$194M$128M$714M$295M

DTIL vs DBVT vs SANA vs IMVT vs BEAMLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

DTIL
DBVT
SANA
IMVT
BEAM
StockFeb 21May 26Return
Precision BioScienc… (DTIL)1002.1-97.9%
DBV Technologies S.… (DBVT)10037.4-62.6%
Sana Biotechnology,… (SANA)10011.4-88.6%
Immunovant, Inc. (IMVT)100172.5+72.5%
Beam Therapeutics I… (BEAM)10035.3-64.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: DTIL vs DBVT vs SANA vs IMVT vs BEAM

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: DBVT and BEAM are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Beam Therapeutics Inc. is the stronger pick specifically for growth and revenue expansion and operational efficiency and capital deployment. IMVT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
DTIL
Precision BioSciences, Inc.
The Defensive Pick

DTIL is the clearest fit if your priority is defensive.

  • Beta 1.37, current ratio 13.32x
Best for: defensive
DBVT
DBV Technologies S.A.
The Income Pick

DBVT carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 0 yrs, beta 1.26
  • Lower volatility, beta 1.26, Low D/E 12.8%, current ratio 3.67x
  • Beta 1.26 vs SANA's 2.69, lower leverage
  • +110.4% vs DTIL's +44.4%
Best for: income & stability and sleep-well-at-night
SANA
Sana Biotechnology, Inc.
The Healthcare Pick

Among these 5 stocks, SANA doesn't own a clear edge in any measured category.

Best for: healthcare exposure
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT ranks third and is worth considering specifically for long-term compounding.

  • 173.6% 10Y total return vs BEAM's 67.8%
  • 3.2% margin vs DTIL's -98.7%
Best for: long-term compounding
BEAM
Beam Therapeutics Inc.
The Growth Play

BEAM is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
  • 120.0% revenue growth vs DBVT's -100.0%
  • -4.6% ROA vs DBVT's -89.0%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBEAM logoBEAM120.0% revenue growth vs DBVT's -100.0%
Quality / MarginsIMVT logoIMVT3.2% margin vs DTIL's -98.7%
Stability / SafetyDBVT logoDBVTBeta 1.26 vs SANA's 2.69, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)DBVT logoDBVT+110.4% vs DTIL's +44.4%
Efficiency (ROA)BEAM logoBEAM-4.6% ROA vs DBVT's -89.0%

DTIL vs DBVT vs SANA vs IMVT vs BEAM — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

DTILPrecision BioSciences, Inc.
FY 2025
License
100.0%$8M
DBVTDBV Technologies S.A.

Segment breakdown not available.

SANASana Biotechnology, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

BEAMBeam Therapeutics Inc.

Segment breakdown not available.

DTIL vs DBVT vs SANA vs IMVT vs BEAM — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLDTILLAGGINGSANA

Income & Cash Flow (Last 12 Months)

DTIL leads this category, winning 4 of 6 comparable metrics.

BEAM and IMVT operate at a comparable scale, with $132M and $0 in trailing revenue. BEAM is the more profitable business, keeping -49.2% of every revenue dollar as net income compared to DTIL's -98.7%. On growth, DTIL holds the edge at +372.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricDTIL logoDTILPrecision BioScie…DBVT logoDBVTDBV Technologies …SANA logoSANASana Biotechnolog…IMVT logoIMVTImmunovant, Inc.BEAM logoBEAMBeam Therapeutics…
RevenueTrailing 12 months$45M$0$0$0$132M
EBITDAEarnings before interest/tax-$36M-$112M-$225M-$487M-$355M
Net IncomeAfter-tax profit-$44M-$168M-$234M-$464M-$65M
Free Cash FlowCash after capex-$59M-$151M-$159M-$423M-$384M
Gross MarginGross profit ÷ Revenue+97.0%-64.2%
Operating MarginEBIT ÷ Revenue-86.8%-2.8%
Net MarginNet income ÷ Revenue-98.7%-49.2%
FCF MarginFCF ÷ Revenue-130.4%-2.9%
Rev. Growth (YoY)Latest quarter vs prior year+372.7%-100.0%
EPS Growth (YoY)Latest quarter vs prior year+67.2%+91.5%+36.0%+19.7%+26.6%
DTIL leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — DTIL and DBVT and BEAM each lead in 1 of 3 comparable metrics.
MetricDTIL logoDTILPrecision BioScie…DBVT logoDBVTDBV Technologies …SANA logoSANASana Biotechnolog…IMVT logoIMVTImmunovant, Inc.BEAM logoBEAMBeam Therapeutics…
Market CapShares × price$96M$1712.35T$918M$5.5B$3.2B
Enterprise ValueMkt cap + debt − cash$14M$1712.35T$885M$4.8B$3.2B
Trailing P/EPrice ÷ TTM EPS-2.06x-0.76x-3.02x-9.97x-38.85x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue2.80x23.14x
Price / BookPrice ÷ Book value/share1.04x0.66x3.23x5.83x2.51x
Price / FCFMarket cap ÷ FCF
Evenly matched — DTIL and DBVT and BEAM each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

BEAM leads this category, winning 6 of 9 comparable metrics.

BEAM delivers a -5.9% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SANA's 0.38x. On the Piotroski fundamental quality scale (0–9), DBVT scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.

MetricDTIL logoDTILPrecision BioScie…DBVT logoDBVTDBV Technologies …SANA logoSANASana Biotechnolog…IMVT logoIMVTImmunovant, Inc.BEAM logoBEAMBeam Therapeutics…
ROE (TTM)Return on equity-81.2%-130.2%-120.0%-47.1%-5.9%
ROA (TTM)Return on assets-35.5%-89.0%-53.8%-44.1%-4.6%
ROICReturn on invested capital-7.3%-86.1%-31.1%
ROCEReturn on capital employed-39.1%-145.7%-57.0%-66.1%-33.3%
Piotroski ScoreFundamental quality 0–924224
Debt / EquityFinancial leverage0.31x0.13x0.38x0.00x0.24x
Net DebtTotal debt minus cash-$82M-$172M-$33M-$714M-$1M
Cash & Equiv.Liquid assets$111M$194M$128M$714M$295M
Total DebtShort + long-term debt$29M$22M$94M$98,000$294M
Interest CoverageEBIT ÷ Interest expense-24.69x-189.82x1.08x
BEAM leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $290 for DTIL. Over the past 12 months, DBVT leads with a +110.4% total return vs DTIL's +44.4%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs DTIL's -33.6% — a key indicator of consistent wealth creation.

MetricDTIL logoDTILPrecision BioScie…DBVT logoDBVTDBV Technologies …SANA logoSANASana Biotechnolog…IMVT logoIMVTImmunovant, Inc.BEAM logoBEAMBeam Therapeutics…
YTD ReturnYear-to-date+82.4%+4.9%-16.5%+5.1%+16.0%
1-Year ReturnPast 12 months+44.4%+110.4%+105.9%+96.1%+93.9%
3-Year ReturnCumulative with dividends-70.7%+19.7%-36.8%+40.9%-5.6%
5-Year ReturnCumulative with dividends-97.1%-69.1%-80.7%+62.4%-55.6%
10-Year ReturnCumulative with dividends-98.6%-87.0%-90.0%+173.6%+67.8%
CAGR (3Y)Annualised 3-year return-33.6%+6.2%-14.2%+12.1%-1.9%
IMVT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — DBVT and IMVT each lead in 1 of 2 comparable metrics.

DBVT is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than SANA's 2.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs SANA's 53.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricDTIL logoDTILPrecision BioScie…DBVT logoDBVTDBV Technologies …SANA logoSANASana Biotechnolog…IMVT logoIMVTImmunovant, Inc.BEAM logoBEAMBeam Therapeutics…
Beta (5Y)Sensitivity to S&P 5001.37x1.26x2.69x1.37x2.14x
52-Week HighHighest price in past year$8.82$26.18$6.55$30.09$36.44
52-Week LowLowest price in past year$3.53$7.53$1.60$13.36$15.35
% of 52W HighCurrent price vs 52-week peak+84.8%+76.3%+53.4%+90.5%+86.4%
RSI (14)Momentum oscillator 0–10059.448.159.060.260.9
Avg Volume (50D)Average daily shares traded285K252K3.1M1.4M2.0M
Evenly matched — DBVT and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: DBVT as "Buy", SANA as "Buy", IMVT as "Buy", BEAM as "Buy". Consensus price targets imply 147.7% upside for SANA (target: $9) vs 29.7% for BEAM (target: $41).

MetricDTIL logoDTILPrecision BioScie…DBVT logoDBVTDBV Technologies …SANA logoSANASana Biotechnolog…IMVT logoIMVTImmunovant, Inc.BEAM logoBEAMBeam Therapeutics…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$46.33$8.67$45.50$40.83
# AnalystsCovering analysts15112327
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

DTIL leads in 1 of 6 categories (Income & Cash Flow). BEAM leads in 1 (Profitability & Efficiency). 2 tied.

Best OverallPrecision BioSciences, Inc. (DTIL)Leads 1 of 6 categories
Loading custom metrics...

DTIL vs DBVT vs SANA vs IMVT vs BEAM: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is DTIL or DBVT or SANA or IMVT or BEAM a better buy right now?

For growth investors, Beam Therapeutics Inc.

(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -50. 1% for Precision BioSciences, Inc. (DTIL). Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — DTIL or DBVT or SANA or IMVT or BEAM?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -97. 1% for Precision BioSciences, Inc. (DTIL). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus DTIL's -98. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — DTIL or DBVT or SANA or IMVT or BEAM?

By beta (market sensitivity over 5 years), DBV Technologies S.

A. (DBVT) is the lower-risk stock at 1. 26β versus Sana Biotechnology, Inc. 's 2. 69β — meaning SANA is approximately 114% more volatile than DBVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 38% for Sana Biotechnology, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — DTIL or DBVT or SANA or IMVT or BEAM?

By revenue growth (latest reported year), Beam Therapeutics Inc.

(BEAM) is pulling ahead at 120. 0% versus -50. 1% for Precision BioSciences, Inc. (DTIL). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -449. 0% for Precision BioSciences, Inc.. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — DTIL or DBVT or SANA or IMVT or BEAM?

DBV Technologies S.

A. (DBVT) is the more profitable company, earning 0. 0% net margin versus -136. 0% for Precision BioSciences, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -274. 6% for BEAM. At the gross margin level — before operating expenses — DTIL leads at 92. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — DTIL or DBVT or SANA or IMVT or BEAM?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is DTIL or DBVT or SANA or IMVT or BEAM better for a retirement portfolio?

For long-horizon retirement investors, Immunovant, Inc.

(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Sana Biotechnology, Inc. (SANA) carries a higher beta of 2. 69 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, SANA: -90. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between DTIL and DBVT and SANA and IMVT and BEAM?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: DTIL is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; SANA is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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