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KO
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PFE
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Stock Comparison

EDSA vs HALO vs KO vs JPM vs PFE

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
EDSA
Edesa Biotech, Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$52M
5Y Perf.-83.1%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$8.24B
5Y Perf.+159.2%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+84.9%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+241.0%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$149.09B
5Y Perf.-15.5%

EDSA vs HALO vs KO vs JPM vs PFE — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
EDSA logoEDSA
HALO logoHALO
KO logoKO
JPM logoJPM
PFE logoPFE
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicBanks - DiversifiedDrug Manufacturers - General
Market Cap$52M$8.24B$355.61B$896.00B$149.09B
Revenue (TTM)$0.00$1.51B$49.28B$280.33B$63.31B
Net Income (TTM)$-10M$349M$13.70B$57.05B$7.49B
Gross Margin76.9%61.7%60.0%69.3%
Operating Margin57.0%29.3%25.9%23.4%
Forward P/E8.6x25.3x14.4x8.9x
Total Debt$0.00$2.14B$45.49B$942.38B$67.42B
Cash & Equiv.$11M$134M$10.27B$343.34B$1.14B

EDSA vs HALO vs KO vs JPM vs PFELong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

EDSA
HALO
KO
JPM
PFE
StockJun 20Jun 26Return
Edesa Biotech, Inc. (EDSA)10016.9-83.1%
Halozyme Therapeuti… (HALO)100259.2+159.2%
The Coca-Cola Compa… (KO)100184.9+84.9%
JPMorgan Chase & Co. (JPM)100341.0+241.0%
Pfizer Inc. (PFE)10084.5-15.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: EDSA vs HALO vs KO vs JPM vs PFE

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HALO leads in 3 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Pfizer Inc. is the stronger pick specifically for capital preservation and lower volatility and dividend income and shareholder returns. EDSA and KO also each lead in at least one category. This set spans 3 sectors — these stocks serve different portfolio roles, not just different price points.
🥇HALO emerged as the overall leader. Track its performance:
EDSA
Edesa Biotech, Inc.
The Momentum Pick

EDSA ranks third and is worth considering specifically for momentum.

  • +195.9% vs PFE's +12.4%
Best for: momentum
HALO
Halozyme Therapeutics, Inc.
The Growth Play

HALO carries the broadest edge in this set and is the clearest fit for growth exposure and valuation efficiency.

  • Rev growth 37.6%, EPS growth -25.4%, 3Y rev CAGR 28.4%
  • PEG 0.37 vs KO's 2.26
  • 37.6% revenue growth vs EDSA's -82.2%
  • Lower P/E (8.6x vs 8.9x)
Best for: growth exposure and valuation efficiency
KO
The Coca-Cola Company
The Quality Compounder

KO is the clearest fit if your priority is quality.

  • 27.8% margin vs EDSA's 0.0%
Best for: quality
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM is the clearest fit if your priority is long-term compounding.

  • 465.8% 10Y total return vs HALO's 7.0%
Best for: long-term compounding
PFE
Pfizer Inc.
The Income Pick

PFE is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • Dividend streak 15 yrs, beta 0.38, yield 6.6%
  • Lower volatility, beta 0.38, Low D/E 77.7%, current ratio 1.16x
  • Beta 0.38, yield 6.6%, current ratio 1.16x
  • Beta 0.38 vs JPM's 0.94, lower leverage
Best for: income & stability and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthHALO logoHALO37.6% revenue growth vs EDSA's -82.2%
ValueHALO logoHALOLower P/E (8.6x vs 8.9x)
Quality / MarginsKO logoKO27.8% margin vs EDSA's 0.0%
Stability / SafetyPFE logoPFEBeta 0.38 vs JPM's 0.94, lower leverage
DividendsPFE logoPFE6.6% yield, 15-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend)
Momentum (1Y)EDSA logoEDSA+195.9% vs PFE's +12.4%
Efficiency (ROA)HALO logoHALO14.7% ROA vs EDSA's -75.2%, ROIC 32.1% vs -452.3%

EDSA vs HALO vs KO vs JPM vs PFE — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
EDSAEdesa Biotech, Inc.
FY 2018
Product
100.0%$211,849
HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B

EDSA vs HALO vs KO vs JPM vs PFE — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHALOLAGGINGEDSA

Income & Cash Flow (Last 12 Months)

HALO leads this category, winning 5 of 6 comparable metrics.

JPM and EDSA operate at a comparable scale, with $280.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to PFE's 11.8%. On growth, HALO holds the edge at +42.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricEDSA logoEDSAEdesa Biotech, In…HALO logoHALOHalozyme Therapeu…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …PFE logoPFEPfizer Inc.
RevenueTrailing 12 months$0$1.5B$49.3B$280.3B$63.3B
EBITDAEarnings before interest/tax-$11M$961M$15.5B$81.4B$21.0B
Net IncomeAfter-tax profit-$10M$349M$13.7B$57.0B$7.5B
Free Cash FlowCash after capex-$8M$668M$12.6B$100.9B$9.5B
Gross MarginGross profit ÷ Revenue+76.9%+61.7%+60.0%+69.3%
Operating MarginEBIT ÷ Revenue+57.0%+29.3%+25.9%+23.4%
Net MarginNet income ÷ Revenue+23.1%+27.8%+20.4%+11.8%
FCF MarginFCF ÷ Revenue+44.3%+25.5%+36.0%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year+42.2%+12.1%+5.4%
EPS Growth (YoY)Latest quarter vs prior year-66.7%+31.2%+18.2%+16.0%-9.5%
HALO leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

PFE leads this category, winning 3 of 7 comparable metrics.

At 16.0x trailing earnings, JPM trades at a 41% valuation discount to KO's 27.2x P/E. Adjusting for growth (PEG ratio), JPM offers better value at 0.90x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricEDSA logoEDSAEdesa Biotech, In…HALO logoHALOHalozyme Therapeu…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …PFE logoPFEPfizer Inc.
Market CapShares × price$52M$8.2B$355.6B$896.0B$149.1B
Enterprise ValueMkt cap + debt − cash$41M$10.3B$390.8B$1.50T$215.4B
Trailing P/EPrice ÷ TTM EPS-4.57x27.15x27.18x16.00x19.27x
Forward P/EPrice ÷ next-FY EPS est.8.57x25.27x14.40x8.85x
PEG RatioP/E ÷ EPS growth rate1.18x2.43x0.90x
EV / EBITDAEnterprise value multiple11.34x26.39x18.36x10.59x
Price / SalesMarket cap ÷ Revenue5.90x7.42x3.20x2.38x
Price / BookPrice ÷ Book value/share2.64x176.41x10.40x2.47x1.72x
Price / FCFMarket cap ÷ FCF12.79x67.15x8.88x16.43x
PFE leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

HALO leads this category, winning 5 of 9 comparable metrics.

HALO delivers a 126.3% return on equity — every $100 of shareholder capital generates $126 in annual profit, vs $-82 for EDSA. PFE carries lower financial leverage with a 0.78x debt-to-equity ratio, signaling a more conservative balance sheet compared to HALO's 43.89x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs EDSA's 2/9, reflecting strong financial health.

MetricEDSA logoEDSAEdesa Biotech, In…HALO logoHALOHalozyme Therapeu…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …PFE logoPFEPfizer Inc.
ROE (TTM)Return on equity-82.3%+126.3%+41.1%+15.9%+8.3%
ROA (TTM)Return on assets-75.2%+14.7%+13.1%+1.3%+3.6%
ROICReturn on invested capital-4.5%+32.1%+15.8%+4.5%+7.5%
ROCEReturn on capital employed-109.6%+38.2%+17.3%+8.9%+9.0%
Piotroski ScoreFundamental quality 0–925757
Debt / EquityFinancial leverage43.89x1.33x2.60x0.78x
Net DebtTotal debt minus cash-$11M$2.0B$35.2B$599.0B$66.3B
Cash & Equiv.Liquid assets$11M$134M$10.3B$343.3B$1.1B
Total DebtShort + long-term debt$0$2.1B$45.5B$942.4B$67.4B
Interest CoverageEBIT ÷ Interest expense44.97x10.70x0.74x4.02x
HALO leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JPM leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in JPM five years ago would be worth $21,820 today (with dividends reinvested), compared to $1,441 for EDSA. Over the past 12 months, EDSA leads with a +195.9% total return vs PFE's +12.4%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.6% vs PFE's -7.8% — a key indicator of consistent wealth creation.

MetricEDSA logoEDSAEdesa Biotech, In…HALO logoHALOHalozyme Therapeu…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …PFE logoPFEPfizer Inc.
YTD ReturnYear-to-date+286.7%-1.2%+20.3%-0.5%+7.5%
1-Year ReturnPast 12 months+195.9%+27.4%+17.2%+21.8%+12.4%
3-Year ReturnCumulative with dividends-1.4%+106.4%+47.0%+138.2%-21.6%
5-Year ReturnCumulative with dividends-85.6%+60.3%+65.6%+118.2%-13.0%
10-Year ReturnCumulative with dividends-99.3%+701.6%+121.1%+465.8%+25.8%
CAGR (3Y)Annualised 3-year return-0.5%+27.3%+13.7%+33.6%-7.8%
JPM leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than JPM's 0.94 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs EDSA's 28.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricEDSA logoEDSAEdesa Biotech, In…HALO logoHALOHalozyme Therapeu…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …PFE logoPFEPfizer Inc.
Beta (5Y)Sensitivity to S&P 500-0.18x0.58x-0.20x0.94x0.38x
52-Week HighHighest price in past year$20.32$82.22$84.04$337.25$28.75
52-Week LowLowest price in past year$0.72$51.06$65.35$262.71$23.11
% of 52W HighCurrent price vs 52-week peak+28.5%+84.5%+98.3%+95.1%+91.2%
RSI (14)Momentum oscillator 0–10036.857.160.659.153.2
Avg Volume (50D)Average daily shares traded612K1.5M12.7M7.0M28.5M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — KO and PFE each lead in 1 of 2 comparable metrics.

Analyst consensus: EDSA as "Buy", HALO as "Buy", KO as "Buy", JPM as "Buy", PFE as "Hold". Consensus price targets imply 27.0% upside for HALO (target: $88) vs 2.1% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.56% vs JPM's 1.86%.

MetricEDSA logoEDSAEdesa Biotech, In…HALO logoHALOHalozyme Therapeu…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …PFE logoPFEPfizer Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyHold
Price TargetConsensus 12-month target$88.25$86.13$339.75$26.75
# AnalystsCovering analysts227486139
Dividend YieldAnnual dividend ÷ price+2.5%+1.9%+6.6%
Dividend StreakConsecutive years of raises561515
Dividend / ShareAnnual DPS$2.04$5.95$1.72
Buyback YieldShare repurchases ÷ mkt cap0.0%+4.2%+0.2%+3.9%0.0%
Evenly matched — KO and PFE each lead in 1 of 2 comparable metrics.
Key Takeaway

HALO leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PFE leads in 1 (Valuation Metrics). 1 tied.

Best OverallHalozyme Therapeutics, Inc. (HALO)Leads 2 of 6 categories
Loading custom metrics...

EDSA vs HALO vs KO vs JPM vs PFE: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is EDSA or HALO or KO or JPM or PFE a better buy right now?

For growth investors, Halozyme Therapeutics, Inc.

(HALO) is the stronger pick with 37. 6% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). JPMorgan Chase & Co. (JPM) offers the better valuation at 16. 0x trailing P/E (14. 4x forward), making it the more compelling value choice. Analysts rate Edesa Biotech, Inc. (EDSA) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — EDSA or HALO or KO or JPM or PFE?

On trailing P/E, JPMorgan Chase & Co.

(JPM) is the cheapest at 16. 0x versus The Coca-Cola Company at 27. 2x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 37x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — EDSA or HALO or KO or JPM or PFE?

Over the past 5 years, JPMorgan Chase & Co.

(JPM) delivered a total return of +118. 2%, compared to -85. 6% for Edesa Biotech, Inc. (EDSA). Over 10 years, the gap is even starker: HALO returned +701. 6% versus EDSA's -99. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — EDSA or HALO or KO or JPM or PFE?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus JPMorgan Chase & Co. 's 0. 94β — meaning JPM is approximately -571% more volatile than KO relative to the S&P 500. On balance sheet safety, Pfizer Inc. (PFE) carries a lower debt/equity ratio of 78% versus 44% for Halozyme Therapeutics, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — EDSA or HALO or KO or JPM or PFE?

By revenue growth (latest reported year), Halozyme Therapeutics, Inc.

(HALO) is pulling ahead at 37. 6% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Edesa Biotech, Inc. grew EPS 34. 2% year-over-year, compared to -25. 4% for Halozyme Therapeutics, Inc.. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — EDSA or HALO or KO or JPM or PFE?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus 0. 0% for Edesa Biotech, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for EDSA. At the gross margin level — before operating expenses — HALO leads at 78. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is EDSA or HALO or KO or JPM or PFE more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 37x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 6x forward P/E versus 25. 3x for The Coca-Cola Company — 16. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for HALO: 27. 0% to $88. 25.

08

Which pays a better dividend — EDSA or HALO or KO or JPM or PFE?

In this comparison, PFE (6.

6% yield), KO (2. 5% yield), JPM (1. 9% yield) pay a dividend. EDSA, HALO do not pay a meaningful dividend and should not be held primarily for income.

09

Is EDSA or HALO or KO or JPM or PFE better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, HALO: +701. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between EDSA and HALO and KO and JPM and PFE?

These companies operate in different sectors (EDSA (Healthcare) and HALO (Healthcare) and KO (Consumer Defensive) and JPM (Financial Services) and PFE (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: EDSA is a small-cap quality compounder stock; HALO is a small-cap high-growth stock; KO is a large-cap quality compounder stock; JPM is a large-cap deep-value stock; PFE is a mid-cap income-oriented stock. KO, JPM, PFE pay a dividend while EDSA, HALO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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