Biotechnology
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ELTX vs IMVT vs NKTR vs ADCT vs IMCR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
ELTX vs IMVT vs NKTR vs ADCT vs IMCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $178M | $5.53B | $1.69B | $478M | $1.55B |
| Revenue (TTM) | $0.00 | $0.00 | $55M | $79M | $386M |
| Net Income (TTM) | $-40M | $-464M | $-164M | $-137M | $-19M |
| Gross Margin | — | — | 99.6% | 90.7% | 98.8% |
| Operating Margin | — | — | -237.9% | -149.6% | -7.6% |
| Total Debt | $5M | $98K | $149M | $439M | $44M |
| Cash & Equiv. | $19M | $714M | $15M | $261M | $468M |
ELTX vs IMVT vs NKTR vs ADCT vs IMCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Nov 23 | May 26 | Return |
|---|---|---|---|
| Elicio Therapeutics… (ELTX) | 100 | 162.8 | +62.8% |
| Immunovant, Inc. (IMVT) | 100 | 69.6 | -30.4% |
| Nektar Therapeutics (NKTR) | 100 | 1134.3 | +1034.3% |
| ADC Therapeutics S.… (ADCT) | 100 | 453.0 | +353.0% |
| Immunocore Holdings… (IMCR) | 100 | 58.1 | -41.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ELTX vs IMVT vs NKTR vs ADCT vs IMCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ELTX is the #2 pick in this set and the best alternative if growth is your priority.
- 24.2% revenue growth vs NKTR's -43.9%
IMVT ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.
- 173.6% 10Y total return vs ELTX's 69.9%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
- 3.2% margin vs NKTR's -297.1%
NKTR is the clearest fit if your priority is momentum.
- +8.2% vs IMCR's +2.3%
Among these 5 stocks, ADCT doesn't own a clear edge in any measured category.
IMCR carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.86
- Rev growth 20.0%, EPS growth 48.0%, 3Y rev CAGR 27.3%
- Beta 0.86 vs ADCT's 1.89
- -1.7% ROA vs ELTX's -141.6%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 24.2% revenue growth vs NKTR's -43.9% | |
| Quality / Margins | 3.2% margin vs NKTR's -297.1% | |
| Stability / Safety | Beta 0.86 vs ADCT's 1.89 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +8.2% vs IMCR's +2.3% | |
| Efficiency (ROA) | -1.7% ROA vs ELTX's -141.6% |
ELTX vs IMVT vs NKTR vs ADCT vs IMCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ELTX vs IMVT vs NKTR vs ADCT vs IMCR — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
IMCR leads in 3 of 6 categories
NKTR leads 1 • ELTX leads 0 • IMVT leads 0 • ADCT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
IMCR leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IMCR and IMVT operate at a comparable scale, with $386M and $0 in trailing revenue. Profitability is closely matched — net margins range from -4.9% (IMCR) to -3.0% (NKTR). On growth, IMCR holds the edge at +13.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $55M | $79M | $386M |
| EBITDAEarnings before interest/tax | -$37M | -$487M | -$130M | -$117M | -$27M |
| Net IncomeAfter-tax profit | -$40M | -$464M | -$164M | -$137M | -$19M |
| Free Cash FlowCash after capex | -$37M | -$423M | -$209M | -$115M | -$31M |
| Gross MarginGross profit ÷ Revenue | — | — | +99.6% | +90.7% | +98.8% |
| Operating MarginEBIT ÷ Revenue | — | — | -2.4% | -149.6% | -7.6% |
| Net MarginNet income ÷ Revenue | — | — | -3.0% | -173.0% | -4.9% |
| FCF MarginFCF ÷ Revenue | — | — | -3.8% | -144.7% | -8.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | -25.3% | -9.5% | +13.6% |
| EPS Growth (YoY)Latest quarter vs prior year | +60.9% | +19.7% | -4.5% | +41.7% | +157.5% |
Valuation Metrics
IMCR leads this category, winning 3 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $178M | $5.5B | $1.7B | $478M | $1.6B |
| Enterprise ValueMkt cap + debt − cash | $165M | $4.8B | $1.8B | $656M | $1.1B |
| Trailing P/EPrice ÷ TTM EPS | -3.88x | -9.97x | -8.57x | -3.36x | -57.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | 30.64x | 5.88x | 5.22x |
| Price / BookPrice ÷ Book value/share | 93.69x | 5.83x | 15.66x | — | 4.05x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
IMCR leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
IMCR delivers a -4.8% return on equity — every $100 of shareholder capital generates $-5 in annual profit, vs $-10 for ELTX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ELTX's 3.12x. On the Piotroski fundamental quality scale (0–9), IMCR scores 5/9 vs NKTR's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -9.8% | -47.1% | -4.0% | — | -4.8% |
| ROA (TTM)Return on assets | -141.6% | -44.1% | -62.8% | -44.7% | -1.7% |
| ROICReturn on invested capital | — | — | -57.2% | — | -17.2% |
| ROCEReturn on capital employed | -2.2% | -66.1% | -55.7% | -43.8% | -4.2% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 2 | 4 | 5 |
| Debt / EquityFinancial leverage | 3.12x | 0.00x | 1.66x | — | 0.11x |
| Net DebtTotal debt minus cash | -$13M | -$714M | $134M | $178M | -$424M |
| Cash & Equiv.Liquid assets | $19M | $714M | $15M | $261M | $468M |
| Total DebtShort + long-term debt | $5M | $98,000 | $149M | $439M | $44M |
| Interest CoverageEBIT ÷ Interest expense | -67.66x | — | -4.74x | -1.72x | -2.04x |
Total Returns (Dividends Reinvested)
NKTR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ELTX five years ago would be worth $16,995 today (with dividends reinvested), compared to $1,594 for ADCT. Over the past 12 months, NKTR leads with a +818.2% total return vs IMCR's +2.3%. The 3-year compound annual growth rate (CAGR) favors NKTR at 93.3% vs IMCR's -20.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +24.3% | +5.1% | +92.0% | +6.8% | -9.4% |
| 1-Year ReturnPast 12 months | +101.8% | +96.1% | +818.2% | +196.1% | +2.3% |
| 3-Year ReturnCumulative with dividends | +69.9% | +40.9% | +621.8% | +77.4% | -48.9% |
| 5-Year ReturnCumulative with dividends | +69.9% | +62.4% | -72.3% | -84.1% | -24.0% |
| 10-Year ReturnCumulative with dividends | +69.9% | +173.6% | -59.1% | -87.3% | -29.1% |
| CAGR (3Y)Annualised 3-year return | +19.3% | +12.1% | +93.3% | +21.0% | -20.0% |
Risk & Volatility
Evenly matched — IMVT and IMCR each lead in 1 of 2 comparable metrics.
Risk & Volatility
IMCR is the less volatile stock with a 0.86 beta — it tends to amplify market swings less than ADCT's 1.89 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs ELTX's 67.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.64x | 1.37x | 1.85x | 1.89x | 0.86x |
| 52-Week HighHighest price in past year | $14.93 | $30.09 | $109.00 | $4.97 | $40.72 |
| 52-Week LowLowest price in past year | $4.85 | $13.36 | $7.99 | $1.23 | $27.44 |
| % of 52W HighCurrent price vs 52-week peak | +67.0% | +90.5% | +76.5% | +75.7% | +75.2% |
| RSI (14)Momentum oscillator 0–100 | 42.9 | 60.2 | 53.4 | 48.0 | 55.8 |
| Avg Volume (50D)Average daily shares traded | 135K | 1.4M | 991K | 946K | 409K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ELTX as "Buy", IMVT as "Buy", NKTR as "Buy", ADCT as "Buy", IMCR as "Buy". Consensus price targets imply 99.5% upside for ADCT (target: $8) vs 40.4% for IMCR (target: $43).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $17.00 | $45.50 | $132.83 | $7.50 | $43.00 |
| # AnalystsCovering analysts | 2 | 23 | 33 | 12 | 14 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
IMCR leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). NKTR leads in 1 (Total Returns). 1 tied.
ELTX vs IMVT vs NKTR vs ADCT vs IMCR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ELTX or IMVT or NKTR or ADCT or IMCR a better buy right now?
For growth investors, Immunocore Holdings plc (IMCR) is the stronger pick with 20.
0% revenue growth year-over-year, versus -43. 9% for Nektar Therapeutics (NKTR). Analysts rate Elicio Therapeutics, Inc. (ELTX) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ELTX or IMVT or NKTR or ADCT or IMCR?
Over the past 5 years, Elicio Therapeutics, Inc.
(ELTX) delivered a total return of +69. 9%, compared to -84. 1% for ADC Therapeutics S. A. (ADCT). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus ADCT's -87. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ELTX or IMVT or NKTR or ADCT or IMCR?
By beta (market sensitivity over 5 years), Immunocore Holdings plc (IMCR) is the lower-risk stock at 0.
86β versus ADC Therapeutics S. A. 's 1. 89β — meaning ADCT is approximately 119% more volatile than IMCR relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 3% for Elicio Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ELTX or IMVT or NKTR or ADCT or IMCR?
By revenue growth (latest reported year), Immunocore Holdings plc (IMCR) is pulling ahead at 20.
0% versus -43. 9% for Nektar Therapeutics (NKTR). On earnings-per-share growth, the picture is similar: Immunocore Holdings plc grew EPS 48. 0% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, IMCR leads at 27. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ELTX or IMVT or NKTR or ADCT or IMCR?
Elicio Therapeutics, Inc.
(ELTX) is the more profitable company, earning 0. 0% net margin versus -297. 1% for Nektar Therapeutics — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ELTX leads at 0. 0% versus -236. 8% for NKTR. At the gross margin level — before operating expenses — NKTR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ELTX or IMVT or NKTR or ADCT or IMCR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ELTX or IMVT or NKTR or ADCT or IMCR better for a retirement portfolio?
For long-horizon retirement investors, Immunocore Holdings plc (IMCR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
86)). ADC Therapeutics S. A. (ADCT) carries a higher beta of 1. 89 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMCR: -29. 1%, ADCT: -87. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ELTX and IMVT and NKTR and ADCT and IMCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ELTX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; NKTR is a small-cap quality compounder stock; ADCT is a small-cap quality compounder stock; IMCR is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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