Drug Manufacturers - Specialty & Generic
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EVOK vs ANIP vs AMRX vs PRGO
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
EVOK vs ANIP vs AMRX vs PRGO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
| Market Cap | $19M | $1.86B | $4.15B | $1.62B |
| Revenue (TTM) | $14M | $924M | $3.02B | $4.18B |
| Net Income (TTM) | $-5M | $90M | $72M | $-1.82B |
| Gross Margin | 97.0% | 52.6% | 36.9% | 34.2% |
| Operating Margin | -36.0% | 13.4% | -0.2% | -4.1% |
| Forward P/E | — | 9.0x | 13.3x | 5.5x |
| Total Debt | $5M | $325M | $124M | $3.97B |
| Cash & Equiv. | $14M | $286M | $282M | $532M |
EVOK vs ANIP vs AMRX vs PRGO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | Dec 25 | Return |
|---|---|---|---|
| Evoke Pharma, Inc. (EVOK) | 100 | 3.1 | -96.9% |
| ANI Pharmaceuticals… (ANIP) | 100 | 273.2 | +173.2% |
| Amneal Pharmaceutic… (AMRX) | 100 | 257.1 | +157.1% |
| Perrigo Company plc (PRGO) | 100 | 24.4 | -75.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: EVOK vs ANIP vs AMRX vs PRGO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
EVOK is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 97.8%, EPS growth 90.0%, 3Y rev CAGR 85.0%
- 97.8% revenue growth vs PRGO's -2.8%
- +240.6% vs PRGO's -52.0%
ANIP carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- 80.2% 10Y total return vs AMRX's -56.6%
- Lower volatility, beta 0.56, Low D/E 60.1%, current ratio 2.71x
- Beta 0.56, yield 0.1%, current ratio 2.71x
- 9.7% margin vs PRGO's -43.5%
AMRX lags the leaders in this set but could rank higher in a more targeted comparison.
PRGO is the clearest fit if your priority is income & stability.
- Dividend streak 10 yrs, beta 1.21, yield 9.8%
- Lower P/E (5.5x vs 13.3x)
- 9.8% yield, 10-year raise streak, vs ANIP's 0.1%, (2 stocks pay no dividend)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 97.8% revenue growth vs PRGO's -2.8% | |
| Value | Lower P/E (5.5x vs 13.3x) | |
| Quality / Margins | 9.7% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.56 vs PRGO's 1.21, lower leverage | |
| Dividends | 9.8% yield, 10-year raise streak, vs ANIP's 0.1%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +240.6% vs PRGO's -52.0% | |
| Efficiency (ROA) | 6.4% ROA vs EVOK's -33.4%, ROIC 8.2% vs -6.1% |
EVOK vs ANIP vs AMRX vs PRGO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
EVOK vs ANIP vs AMRX vs PRGO — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ANIP leads in 3 of 6 categories
PRGO leads 2 • EVOK leads 1 • AMRX leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
ANIP leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PRGO is the larger business by revenue, generating $4.2B annually — 289.7x EVOK's $14M. ANIP is the more profitable business, keeping 9.7% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, EVOK holds the edge at +61.4% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $14M | $924M | $3.0B | $4.2B |
| EBITDAEarnings before interest/tax | -$5M | $213M | $169M | $58M |
| Net IncomeAfter-tax profit | -$5M | $90M | $72M | -$1.8B |
| Free Cash FlowCash after capex | -$3M | $172M | $150M | $108M |
| Gross MarginGross profit ÷ Revenue | +97.0% | +52.6% | +36.9% | +34.2% |
| Operating MarginEBIT ÷ Revenue | -36.0% | +13.4% | -0.2% | -4.1% |
| Net MarginNet income ÷ Revenue | -36.2% | +9.7% | +2.4% | -43.5% |
| FCF MarginFCF ÷ Revenue | -23.0% | +18.6% | +5.0% | +2.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | +61.4% | +20.5% | +11.5% | -7.2% |
| EPS Growth (YoY)Latest quarter vs prior year | +52.1% | +85.5% | +2.1% | -56.4% |
Valuation Metrics
PRGO leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 24.7x trailing earnings, ANIP trades at a 59% valuation discount to AMRX's 60.0x P/E. On an enterprise value basis, PRGO's 7.4x EV/EBITDA is more attractive than ANIP's 11.0x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $19M | $1.9B | $4.1B | $1.6B |
| Enterprise ValueMkt cap + debt − cash | $11M | $1.9B | $4.0B | $5.1B |
| Trailing P/EPrice ÷ TTM EPS | -3.91x | 24.66x | 60.00x | -1.14x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 9.02x | 13.29x | 5.53x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | 11.02x | — | 7.43x |
| Price / SalesMarket cap ÷ Revenue | 1.85x | 2.11x | 1.37x | 0.38x |
| Price / BookPrice ÷ Book value/share | 2.98x | 3.21x | 4.44x | 0.55x |
| Price / FCFMarket cap ÷ FCF | — | 10.87x | 15.37x | 11.17x |
Profitability & Efficiency
ANIP leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ANIP delivers a 17.3% return on equity — every $100 of shareholder capital generates $17 in annual profit, vs $-155 for EVOK. AMRX carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRGO's 1.35x. On the Piotroski fundamental quality scale (0–9), AMRX scores 8/9 vs PRGO's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -155.4% | +17.3% | +7.5% | -50.7% |
| ROA (TTM)Return on assets | -33.4% | +6.4% | +2.0% | -19.8% |
| ROICReturn on invested capital | -6.1% | +8.2% | -0.2% | +3.7% |
| ROCEReturn on capital employed | -2.3% | +7.2% | -0.2% | +4.3% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 6 | 8 | 4 |
| Debt / EquityFinancial leverage | 0.73x | 0.60x | 0.13x | 1.35x |
| Net DebtTotal debt minus cash | -$8M | $40M | -$158M | $3.4B |
| Cash & Equiv.Liquid assets | $14M | $286M | $282M | $532M |
| Total DebtShort + long-term debt | $5M | $325M | $124M | $4.0B |
| Interest CoverageEBIT ÷ Interest expense | -9.45x | 3.40x | 2.09x | -7.20x |
Total Returns (Dividends Reinvested)
ANIP leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ANIP five years ago would be worth $24,881 today (with dividends reinvested), compared to $480 for EVOK. Over the past 12 months, EVOK leads with a +240.6% total return vs PRGO's -52.0%. The 3-year compound annual growth rate (CAGR) favors AMRX at 87.0% vs EVOK's -25.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | — | +4.4% | +4.3% | -13.6% |
| 1-Year ReturnPast 12 months | +240.6% | +14.4% | +76.9% | -52.0% |
| 3-Year ReturnCumulative with dividends | -58.8% | +92.2% | +553.5% | -58.1% |
| 5-Year ReturnCumulative with dividends | -95.2% | +148.8% | +148.6% | -60.3% |
| 10-Year ReturnCumulative with dividends | -98.5% | +80.2% | -56.6% | -77.7% |
| CAGR (3Y)Annualised 3-year return | -25.6% | +24.3% | +87.0% | -25.2% |
Risk & Volatility
EVOK leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
EVOK is the less volatile stock with a -0.17 beta — it tends to amplify market swings less than PRGO's 1.21 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EVOK currently trades 100.0% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | -0.17x | 0.56x | 1.08x | 1.21x |
| 52-Week HighHighest price in past year | $11.00 | $99.50 | $15.20 | $28.44 |
| 52-Week LowLowest price in past year | $2.46 | $56.71 | $7.02 | $9.23 |
| % of 52W HighCurrent price vs 52-week peak | +100.0% | +82.3% | +86.8% | +41.2% |
| RSI (14)Momentum oscillator 0–100 | 85.1 | 63.8 | 64.0 | 53.1 |
| Avg Volume (50D)Average daily shares traded | 0 | 348K | 1.7M | 3.3M |
Analyst Outlook
PRGO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ANIP as "Buy", AMRX as "Buy", PRGO as "Hold". Consensus price targets imply 209.1% upside for PRGO (target: $36) vs 28.8% for AMRX (target: $17). PRGO is the only dividend payer here at 9.82% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | — | $124.00 | $17.00 | $36.20 |
| # AnalystsCovering analysts | — | 10 | 16 | 36 |
| Dividend YieldAnnual dividend ÷ price | — | +0.1% | — | +9.8% |
| Dividend StreakConsecutive years of raises | — | 0 | 0 | 10 |
| Dividend / ShareAnnual DPS | — | $0.05 | — | $1.15 |
| Buyback YieldShare repurchases ÷ mkt cap | +0.0% | +0.7% | 0.0% | 0.0% |
ANIP leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRGO leads in 2 (Valuation Metrics, Analyst Outlook).
EVOK vs ANIP vs AMRX vs PRGO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is EVOK or ANIP or AMRX or PRGO a better buy right now?
For growth investors, Evoke Pharma, Inc.
(EVOK) is the stronger pick with 97. 8% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). ANI Pharmaceuticals, Inc. (ANIP) offers the better valuation at 24. 7x trailing P/E (9. 0x forward), making it the more compelling value choice. Analysts rate ANI Pharmaceuticals, Inc. (ANIP) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — EVOK or ANIP or AMRX or PRGO?
On trailing P/E, ANI Pharmaceuticals, Inc.
(ANIP) is the cheapest at 24. 7x versus Amneal Pharmaceuticals, Inc. at 60. 0x. On forward P/E, Perrigo Company plc is actually cheaper at 5. 5x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — EVOK or ANIP or AMRX or PRGO?
Over the past 5 years, ANI Pharmaceuticals, Inc.
(ANIP) delivered a total return of +148. 8%, compared to -95. 2% for Evoke Pharma, Inc. (EVOK). Over 10 years, the gap is even starker: ANIP returned +80. 2% versus EVOK's -98. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — EVOK or ANIP or AMRX or PRGO?
By beta (market sensitivity over 5 years), Evoke Pharma, Inc.
(EVOK) is the lower-risk stock at -0. 17β versus Perrigo Company plc's 1. 21β — meaning PRGO is approximately -824% more volatile than EVOK relative to the S&P 500. On balance sheet safety, Amneal Pharmaceuticals, Inc. (AMRX) carries a lower debt/equity ratio of 13% versus 135% for Perrigo Company plc — giving it more financial flexibility in a downturn.
05Which is growing faster — EVOK or ANIP or AMRX or PRGO?
By revenue growth (latest reported year), Evoke Pharma, Inc.
(EVOK) is pulling ahead at 97. 8% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: ANI Pharmaceuticals, Inc. grew EPS 419. 2% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, EVOK leads at 85. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — EVOK or ANIP or AMRX or PRGO?
ANI Pharmaceuticals, Inc.
(ANIP) is the more profitable company, earning 8. 9% net margin versus -52. 2% for Evoke Pharma, Inc. — meaning it keeps 8. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ANIP leads at 9. 2% versus -50. 8% for EVOK. At the gross margin level — before operating expenses — EVOK leads at 96. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is EVOK or ANIP or AMRX or PRGO more undervalued right now?
On forward earnings alone, Perrigo Company plc (PRGO) trades at 5.
5x forward P/E versus 13. 3x for Amneal Pharmaceuticals, Inc. — 7. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 209. 1% to $36. 20.
08Which pays a better dividend — EVOK or ANIP or AMRX or PRGO?
In this comparison, PRGO (9.
8% yield) pays a dividend. EVOK, ANIP, AMRX do not pay a meaningful dividend and should not be held primarily for income.
09Is EVOK or ANIP or AMRX or PRGO better for a retirement portfolio?
For long-horizon retirement investors, Evoke Pharma, Inc.
(EVOK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 17)). Both have compounded well over 10 years (EVOK: -98. 5%, AMRX: -56. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between EVOK and ANIP and AMRX and PRGO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: EVOK is a small-cap high-growth stock; ANIP is a small-cap high-growth stock; AMRX is a small-cap quality compounder stock; PRGO is a small-cap income-oriented stock. PRGO pays a dividend while EVOK, ANIP, AMRX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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