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Stock Comparison

GKOS vs ATRC vs NVCR vs IRTC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
GKOS
Glaukos Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$7.81B
5Y Perf.+242.5%
ATRC
AtriCure, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$1.33B
5Y Perf.-45.0%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$2.04B
5Y Perf.-73.5%
IRTC
iRhythm Technologies, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$3.96B
5Y Perf.-2.9%

GKOS vs ATRC vs NVCR vs IRTC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
GKOS logoGKOS
ATRC logoATRC
NVCR logoNVCR
IRTC logoIRTC
IndustryMedical - DevicesMedical - Instruments & SuppliesMedical - Instruments & SuppliesMedical - Devices
Market Cap$7.81B$1.33B$2.04B$3.96B
Revenue (TTM)$551M$552M$674M$788M
Net Income (TTM)$-189M$-5M$-173M$-28M
Gross Margin78.1%75.5%75.2%71.0%
Operating Margin-15.6%-0.4%-27.2%-3.3%
Forward P/E428.7x27422.7x
Total Debt$140M$88M$290M$731M
Cash & Equiv.$91M$167M$103M$236M

GKOS vs ATRC vs NVCR vs IRTCLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

GKOS
ATRC
NVCR
IRTC
StockMay 20May 26Return
Glaukos Corporation (GKOS)100342.5+242.5%
AtriCure, Inc. (ATRC)10055.0-45.0%
NovoCure Limited (NVCR)10026.5-73.5%
iRhythm Technologie… (IRTC)10097.1-2.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: GKOS vs ATRC vs NVCR vs IRTC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ATRC leads in 3 of 7 categories, making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Glaukos Corporation is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. IRTC also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
GKOS
Glaukos Corporation
The Long-Run Compounder

GKOS is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 454.5% 10Y total return vs IRTC's 363.2%
  • 32.3% revenue growth vs NVCR's 8.3%
  • +47.5% vs ATRC's -15.7%
Best for: long-term compounding
ATRC
AtriCure, Inc.
The Defensive Pick

ATRC carries the broadest edge in this set and is the clearest fit for sleep-well-at-night.

  • Lower volatility, beta 0.95, Low D/E 17.9%, current ratio 3.96x
  • Lower P/E (428.7x vs 27422.7x)
  • -0.8% margin vs GKOS's -34.3%
  • -0.7% ROA vs GKOS's -20.1%, ROIC -0.6% vs -9.2%
Best for: sleep-well-at-night
NVCR
NovoCure Limited
The Secondary Option

NVCR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
IRTC
iRhythm Technologies, Inc.
The Income Pick

IRTC is the clearest fit if your priority is income & stability and growth exposure.

  • beta 0.73
  • Rev growth 26.2%, EPS growth 61.7%, 3Y rev CAGR 22.1%
  • Beta 0.73, current ratio 4.63x
  • Beta 0.73 vs NVCR's 2.15
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthGKOS logoGKOS32.3% revenue growth vs NVCR's 8.3%
ValueATRC logoATRCLower P/E (428.7x vs 27422.7x)
Quality / MarginsATRC logoATRC-0.8% margin vs GKOS's -34.3%
Stability / SafetyIRTC logoIRTCBeta 0.73 vs NVCR's 2.15
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)GKOS logoGKOS+47.5% vs ATRC's -15.7%
Efficiency (ROA)ATRC logoATRC-0.7% ROA vs GKOS's -20.1%, ROIC -0.6% vs -9.2%

GKOS vs ATRC vs NVCR vs IRTC — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GKOSGlaukos Corporation
FY 2019
Glaucoma
97.5%$231M
Corneal Health
2.5%$6M
ATRCAtriCure, Inc.
FY 2025
Shipping and Handling
100.0%$2M
NVCRNovoCure Limited

Segment breakdown not available.

IRTCiRhythm Technologies, Inc.
FY 2025
Commercial Payors
52.5%$392M
Centers For Medicare And Medicaid
24.0%$179M
Healthcare Institutions
16.8%$126M
Non-contracted Third-party Payors
6.7%$50M

GKOS vs ATRC vs NVCR vs IRTC — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLATRCLAGGINGIRTC

Income & Cash Flow (Last 12 Months)

ATRC leads this category, winning 4 of 6 comparable metrics.

IRTC and GKOS operate at a comparable scale, with $788M and $551M in trailing revenue. ATRC is the more profitable business, keeping -0.8% of every revenue dollar as net income compared to GKOS's -34.3%. On growth, GKOS holds the edge at +41.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…
RevenueTrailing 12 months$551M$552M$674M$788M
EBITDAEarnings before interest/tax-$40M$13M-$165M-$6M
Net IncomeAfter-tax profit-$189M-$5M-$173M-$28M
Free Cash FlowCash after capex-$18M$54M-$48M$19M
Gross MarginGross profit ÷ Revenue+78.1%+75.5%+75.2%+71.0%
Operating MarginEBIT ÷ Revenue-15.6%-0.4%-27.2%-3.3%
Net MarginNet income ÷ Revenue-34.3%-0.8%-25.7%-3.5%
FCF MarginFCF ÷ Revenue-3.4%+9.7%-7.1%+2.4%
Rev. Growth (YoY)Latest quarter vs prior year+41.2%+14.3%+12.3%+25.7%
EPS Growth (YoY)Latest quarter vs prior year-6.3%+101.6%-100.0%+55.7%
ATRC leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

ATRC leads this category, winning 5 of 5 comparable metrics.
MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…
Market CapShares × price$7.8B$1.3B$2.0B$4.0B
Enterprise ValueMkt cap + debt − cash$7.9B$1.3B$2.2B$4.5B
Trailing P/EPrice ÷ TTM EPS-40.71x-109.50x-14.66x-86.81x
Forward P/EPrice ÷ next-FY EPS est.428.71x27422.73x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple73.24x
Price / SalesMarket cap ÷ Revenue15.40x2.49x3.11x5.31x
Price / BookPrice ÷ Book value/share11.64x2.55x5.86x25.28x
Price / FCFMarket cap ÷ FCF27.56x114.83x
ATRC leads this category, winning 5 of 5 comparable metrics.

Profitability & Efficiency

ATRC leads this category, winning 8 of 9 comparable metrics.

ATRC delivers a -1.0% return on equity — every $100 of shareholder capital generates $-1 in annual profit, vs $-51 for NVCR. ATRC carries lower financial leverage with a 0.18x debt-to-equity ratio, signaling a more conservative balance sheet compared to IRTC's 4.79x. On the Piotroski fundamental quality scale (0–9), IRTC scores 6/9 vs GKOS's 3/9, reflecting solid financial health.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…
ROE (TTM)Return on equity-26.5%-1.0%-50.8%-20.6%
ROA (TTM)Return on assets-20.1%-0.7%-16.5%-2.8%
ROICReturn on invested capital-9.2%-0.6%-16.4%-5.2%
ROCEReturn on capital employed-10.3%-0.6%-28.9%-4.4%
Piotroski ScoreFundamental quality 0–93556
Debt / EquityFinancial leverage0.21x0.18x0.85x4.79x
Net DebtTotal debt minus cash$49M-$79M$187M$495M
Cash & Equiv.Liquid assets$91M$167M$103M$236M
Total DebtShort + long-term debt$140M$88M$290M$731M
Interest CoverageEBIT ÷ Interest expense-18.69x0.47x-96.80x-1.48x
ATRC leads this category, winning 8 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GKOS leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in GKOS five years ago would be worth $17,474 today (with dividends reinvested), compared to $983 for NVCR. Over the past 12 months, GKOS leads with a +47.5% total return vs ATRC's -15.7%. The 3-year compound annual growth rate (CAGR) favors GKOS at 31.5% vs NVCR's -36.4% — a key indicator of consistent wealth creation.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…
YTD ReturnYear-to-date+20.6%-33.1%+36.4%-31.1%
1-Year ReturnPast 12 months+47.5%-15.7%+2.6%-11.9%
3-Year ReturnCumulative with dividends+127.6%-45.0%-74.2%-5.4%
5-Year ReturnCumulative with dividends+74.7%-64.2%-90.2%+54.8%
10-Year ReturnCumulative with dividends+454.5%+84.4%+38.5%+363.2%
CAGR (3Y)Annualised 3-year return+31.5%-18.1%-36.4%-1.8%
GKOS leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — GKOS and IRTC each lead in 1 of 2 comparable metrics.

IRTC is the less volatile stock with a 0.73 beta — it tends to amplify market swings less than NVCR's 2.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GKOS currently trades 91.0% from its 52-week high vs IRTC's 56.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…
Beta (5Y)Sensitivity to S&P 5001.16x0.95x2.15x0.73x
52-Week HighHighest price in past year$146.75$43.18$20.06$212.00
52-Week LowLowest price in past year$73.16$26.10$9.82$112.31
% of 52W HighCurrent price vs 52-week peak+91.0%+60.9%+89.2%+56.9%
RSI (14)Momentum oscillator 0–10061.544.070.953.3
Avg Volume (50D)Average daily shares traded674K678K1.4M525K
Evenly matched — GKOS and IRTC each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: GKOS as "Buy", ATRC as "Buy", NVCR as "Buy", IRTC as "Buy". Consensus price targets imply 95.3% upside for ATRC (target: $51) vs 9.8% for GKOS (target: $147).

MetricGKOS logoGKOSGlaukos Corporati…ATRC logoATRCAtriCure, Inc.NVCR logoNVCRNovoCure LimitedIRTC logoIRTCiRhythm Technolog…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$146.67$51.33$33.50$193.67
# AnalystsCovering analysts24191519
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.8%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ATRC leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). GKOS leads in 1 (Total Returns). 1 tied.

Best OverallAtriCure, Inc. (ATRC)Leads 3 of 6 categories
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GKOS vs ATRC vs NVCR vs IRTC: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is GKOS or ATRC or NVCR or IRTC a better buy right now?

For growth investors, Glaukos Corporation (GKOS) is the stronger pick with 32.

3% revenue growth year-over-year, versus 8. 3% for NovoCure Limited (NVCR). Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — GKOS or ATRC or NVCR or IRTC?

Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +74.

7%, compared to -90. 2% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: GKOS returned +454. 5% versus NVCR's +38. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — GKOS or ATRC or NVCR or IRTC?

By beta (market sensitivity over 5 years), iRhythm Technologies, Inc.

(IRTC) is the lower-risk stock at 0. 73β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 196% more volatile than IRTC relative to the S&P 500. On balance sheet safety, AtriCure, Inc. (ATRC) carries a lower debt/equity ratio of 18% versus 5% for iRhythm Technologies, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — GKOS or ATRC or NVCR or IRTC?

By revenue growth (latest reported year), Glaukos Corporation (GKOS) is pulling ahead at 32.

3% versus 8. 3% for NovoCure Limited (NVCR). On earnings-per-share growth, the picture is similar: AtriCure, Inc. grew EPS 74. 7% year-over-year, compared to -18. 4% for Glaukos Corporation. Over a 3-year CAGR, IRTC leads at 22. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — GKOS or ATRC or NVCR or IRTC?

AtriCure, Inc.

(ATRC) is the more profitable company, earning -2. 1% net margin versus -37. 0% for Glaukos Corporation — meaning it keeps -2. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ATRC leads at -0. 6% versus -23. 5% for NVCR. At the gross margin level — before operating expenses — GKOS leads at 77. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is GKOS or ATRC or NVCR or IRTC more undervalued right now?

On forward earnings alone, AtriCure, Inc.

(ATRC) trades at 428. 7x forward P/E versus 27422. 7x for iRhythm Technologies, Inc. — 26994. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ATRC: 95. 3% to $51. 33.

07

Which pays a better dividend — GKOS or ATRC or NVCR or IRTC?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is GKOS or ATRC or NVCR or IRTC better for a retirement portfolio?

For long-horizon retirement investors, iRhythm Technologies, Inc.

(IRTC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 73), +363. 2% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IRTC: +363. 2%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between GKOS and ATRC and NVCR and IRTC?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: GKOS is a small-cap high-growth stock; ATRC is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock; IRTC is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.

Stocks Like

GKOS

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 20%
  • Gross Margin > 46%
Run This Screen
Stocks Like

ATRC

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 7%
  • Gross Margin > 45%
Run This Screen
Stocks Like

NVCR

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 45%
Run This Screen
Stocks Like

IRTC

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 12%
  • Gross Margin > 42%
Run This Screen
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Beat Both

Find stocks that outperform GKOS and ATRC and NVCR and IRTC on the metrics below

Revenue Growth>
%
(GKOS: 41.2% · ATRC: 14.3%)

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