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Stock Comparison

GKOS vs EW vs MDT vs ATRC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
GKOS
Glaukos Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$7.85B
5Y Perf.+244.2%
EW
Edwards Lifesciences Corporation

Medical - Devices

HealthcareNYSE • US
Market Cap$47.72B
5Y Perf.+10.5%
MDT
Medtronic plc

Medical - Devices

HealthcareNYSE • IE
Market Cap$99.94B
5Y Perf.-20.9%
ATRC
AtriCure, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$1.41B
5Y Perf.-41.9%

GKOS vs EW vs MDT vs ATRC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
GKOS logoGKOS
EW logoEW
MDT logoMDT
ATRC logoATRC
IndustryMedical - DevicesMedical - DevicesMedical - DevicesMedical - Instruments & Supplies
Market Cap$7.85B$47.72B$99.94B$1.41B
Revenue (TTM)$551M$6.07B$35.48B$552M
Net Income (TTM)$-189M$1.07B$4.61B$-5M
Gross Margin78.1%78.1%61.9%75.5%
Operating Margin-15.6%26.7%17.9%-0.4%
Forward P/E27.5x14.1x370.7x
Total Debt$140M$705M$28.52B$88M
Cash & Equiv.$91M$2.94B$2.22B$167M

GKOS vs EW vs MDT vs ATRCLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

GKOS
EW
MDT
ATRC
StockMay 20May 26Return
Glaukos Corporation (GKOS)100344.2+244.2%
Edwards Lifescience… (EW)100110.5+10.5%
Medtronic plc (MDT)10079.1-20.9%
AtriCure, Inc. (ATRC)10058.1-41.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: GKOS vs EW vs MDT vs ATRC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: MDT leads in 4 of 7 categories, making it the strongest pick for valuation and capital efficiency and capital preservation and lower volatility. Glaukos Corporation is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. EW also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
GKOS
Glaukos Corporation
The Growth Play

GKOS is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 32.3%, EPS growth -18.4%, 3Y rev CAGR 21.5%
  • 457.1% 10Y total return vs EW's 133.4%
  • 32.3% revenue growth vs MDT's 3.6%
  • +52.0% vs ATRC's -8.3%
Best for: growth exposure and long-term compounding
EW
Edwards Lifesciences Corporation
The Defensive Pick

EW is the clearest fit if your priority is sleep-well-at-night and valuation efficiency.

  • Lower volatility, beta 0.65, Low D/E 6.8%, current ratio 3.72x
  • PEG 3.89 vs MDT's 36.00
  • 17.6% margin vs GKOS's -34.3%
Best for: sleep-well-at-night and valuation efficiency
MDT
Medtronic plc
The Income Pick

MDT carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • Dividend streak 36 yrs, beta 0.47, yield 3.6%
  • Beta 0.47, yield 3.6%, current ratio 1.85x
  • Lower P/E (14.1x vs 370.7x)
  • Beta 0.47 vs GKOS's 1.20
Best for: income & stability and defensive
ATRC
AtriCure, Inc.
The Secondary Option

ATRC lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthGKOS logoGKOS32.3% revenue growth vs MDT's 3.6%
ValueMDT logoMDTLower P/E (14.1x vs 370.7x)
Quality / MarginsEW logoEW17.6% margin vs GKOS's -34.3%
Stability / SafetyMDT logoMDTBeta 0.47 vs GKOS's 1.20
DividendsMDT logoMDT3.6% yield; 36-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)GKOS logoGKOS+52.0% vs ATRC's -8.3%
Efficiency (ROA)MDT logoMDT175.8% ROA vs GKOS's -20.1%, ROIC 6.0% vs -9.2%

GKOS vs EW vs MDT vs ATRC — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GKOSGlaukos Corporation
FY 2019
Glaucoma
97.5%$231M
Corneal Health
2.5%$6M
EWEdwards Lifesciences Corporation
FY 2025
Transcatheter Heart Valves
74.0%$4.5B
Surgical Heart Valve Therapy
17.0%$1.0B
Transcatheter Mitral And Tricuspid Therapies
9.1%$551M
MDTMedtronic plc
FY 2025
Cardiac and Vascular Group
37.3%$12.5B
Neuroscience Group
29.4%$9.8B
Medical Surgical
25.1%$8.4B
Diabetes Group
8.2%$2.8B
ATRCAtriCure, Inc.
FY 2025
Shipping and Handling
100.0%$2M

GKOS vs EW vs MDT vs ATRC — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLEWLAGGINGATRC

Income & Cash Flow (Last 12 Months)

EW leads this category, winning 4 of 6 comparable metrics.

MDT is the larger business by revenue, generating $35.5B annually — 64.4x GKOS's $551M. EW is the more profitable business, keeping 17.6% of every revenue dollar as net income compared to GKOS's -34.3%. On growth, GKOS holds the edge at +41.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGKOS logoGKOSGlaukos Corporati…EW logoEWEdwards Lifescien…MDT logoMDTMedtronic plcATRC logoATRCAtriCure, Inc.
RevenueTrailing 12 months$551M$6.1B$35.5B$552M
EBITDAEarnings before interest/tax-$40M$1.8B$9.4B$13M
Net IncomeAfter-tax profit-$189M$1.1B$4.6B-$5M
Free Cash FlowCash after capex-$18M$1.3B$5.4B$54M
Gross MarginGross profit ÷ Revenue+78.1%+78.1%+61.9%+75.5%
Operating MarginEBIT ÷ Revenue-15.6%+26.7%+17.9%-0.4%
Net MarginNet income ÷ Revenue-34.3%+17.6%+13.0%-0.8%
FCF MarginFCF ÷ Revenue-3.4%+22.0%+15.2%+9.7%
Rev. Growth (YoY)Latest quarter vs prior year+41.2%+13.3%+8.8%+14.3%
EPS Growth (YoY)Latest quarter vs prior year-6.3%-75.4%-11.9%+101.6%
EW leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

MDT leads this category, winning 4 of 7 comparable metrics.

At 21.6x trailing earnings, MDT trades at a 52% valuation discount to EW's 45.2x P/E. Adjusting for growth (PEG ratio), EW offers better value at 6.39x vs MDT's 36.00x — a lower PEG means you pay less per unit of expected earnings growth.

MetricGKOS logoGKOSGlaukos Corporati…EW logoEWEdwards Lifescien…MDT logoMDTMedtronic plcATRC logoATRCAtriCure, Inc.
Market CapShares × price$7.9B$47.7B$99.9B$1.4B
Enterprise ValueMkt cap + debt − cash$7.9B$45.5B$126.2B$1.3B
Trailing P/EPrice ÷ TTM EPS-40.90x45.23x21.60x-115.83x
Forward P/EPrice ÷ next-FY EPS est.27.52x14.13x370.67x
PEG RatioP/E ÷ EPS growth rate6.39x36.00x
EV / EBITDAEnterprise value multiple25.37x14.32x77.75x
Price / SalesMarket cap ÷ Revenue15.47x7.86x2.98x2.63x
Price / BookPrice ÷ Book value/share11.69x4.69x2.08x2.70x
Price / FCFMarket cap ÷ FCF35.75x19.28x29.15x
MDT leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

EW leads this category, winning 6 of 9 comparable metrics.

EW delivers a 10.4% return on equity — every $100 of shareholder capital generates $10 in annual profit, vs $-26 for GKOS. EW carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to MDT's 0.59x. On the Piotroski fundamental quality scale (0–9), EW scores 6/9 vs GKOS's 3/9, reflecting solid financial health.

MetricGKOS logoGKOSGlaukos Corporati…EW logoEWEdwards Lifescien…MDT logoMDTMedtronic plcATRC logoATRCAtriCure, Inc.
ROE (TTM)Return on equity-26.5%+10.4%+9.4%-1.0%
ROA (TTM)Return on assets-20.1%+8.0%+175.8%-0.7%
ROICReturn on invested capital-9.2%+15.5%+6.0%-0.6%
ROCEReturn on capital employed-10.3%+14.0%+7.5%-0.6%
Piotroski ScoreFundamental quality 0–93665
Debt / EquityFinancial leverage0.21x0.07x0.59x0.18x
Net DebtTotal debt minus cash$49M-$2.2B$26.3B-$79M
Cash & Equiv.Liquid assets$91M$2.9B$2.2B$167M
Total DebtShort + long-term debt$140M$705M$28.5B$88M
Interest CoverageEBIT ÷ Interest expense-18.69x9.08x0.47x
EW leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GKOS leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in GKOS five years ago would be worth $16,155 today (with dividends reinvested), compared to $3,579 for ATRC. Over the past 12 months, GKOS leads with a +52.0% total return vs ATRC's -8.3%. The 3-year compound annual growth rate (CAGR) favors GKOS at 31.7% vs ATRC's -16.5% — a key indicator of consistent wealth creation.

MetricGKOS logoGKOSGlaukos Corporati…EW logoEWEdwards Lifescien…MDT logoMDTMedtronic plcATRC logoATRCAtriCure, Inc.
YTD ReturnYear-to-date+21.2%-3.0%-18.1%-29.2%
1-Year ReturnPast 12 months+52.0%+10.3%-2.8%-8.3%
3-Year ReturnCumulative with dividends+128.7%-7.0%-4.2%-41.8%
5-Year ReturnCumulative with dividends+61.5%-10.2%-27.7%-64.2%
10-Year ReturnCumulative with dividends+457.1%+133.4%+26.5%+95.1%
CAGR (3Y)Annualised 3-year return+31.7%-2.4%-1.4%-16.5%
GKOS leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — EW and MDT each lead in 1 of 2 comparable metrics.

MDT is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than GKOS's 1.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. EW currently trades 94.2% from its 52-week high vs ATRC's 64.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGKOS logoGKOSGlaukos Corporati…EW logoEWEdwards Lifescien…MDT logoMDTMedtronic plcATRC logoATRCAtriCure, Inc.
Beta (5Y)Sensitivity to S&P 5001.20x0.65x0.47x1.03x
52-Week HighHighest price in past year$146.75$87.89$106.33$43.18
52-Week LowLowest price in past year$73.16$72.30$77.16$26.62
% of 52W HighCurrent price vs 52-week peak+91.4%+94.2%+73.3%+64.4%
RSI (14)Momentum oscillator 0–10063.054.727.345.0
Avg Volume (50D)Average daily shares traded678K4.7M7.8M669K
Evenly matched — EW and MDT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: GKOS as "Buy", EW as "Buy", MDT as "Buy", ATRC as "Buy". Consensus price targets imply 82.3% upside for ATRC (target: $51) vs 9.3% for GKOS (target: $147). MDT is the only dividend payer here at 3.57% yield — a key consideration for income-focused portfolios.

MetricGKOS logoGKOSGlaukos Corporati…EW logoEWEdwards Lifescien…MDT logoMDTMedtronic plcATRC logoATRCAtriCure, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$146.67$96.53$109.50$50.67
# AnalystsCovering analysts24484919
Dividend YieldAnnual dividend ÷ price+3.6%
Dividend StreakConsecutive years of raises36
Dividend / ShareAnnual DPS$2.78
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.9%+3.2%+0.8%
Insufficient data to determine a leader in this category.
Key Takeaway

EW leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). MDT leads in 1 (Valuation Metrics). 1 tied.

Best OverallEdwards Lifesciences Corpor… (EW)Leads 2 of 6 categories
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GKOS vs EW vs MDT vs ATRC: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is GKOS or EW or MDT or ATRC a better buy right now?

For growth investors, Glaukos Corporation (GKOS) is the stronger pick with 32.

3% revenue growth year-over-year, versus 3. 6% for Medtronic plc (MDT). Medtronic plc (MDT) offers the better valuation at 21. 6x trailing P/E (14. 1x forward), making it the more compelling value choice. Analysts rate Glaukos Corporation (GKOS) a "Buy" — based on 24 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — GKOS or EW or MDT or ATRC?

On trailing P/E, Medtronic plc (MDT) is the cheapest at 21.

6x versus Edwards Lifesciences Corporation at 45. 2x. On forward P/E, Medtronic plc is actually cheaper at 14. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Edwards Lifesciences Corporation wins at 3. 89x versus Medtronic plc's 36. 00x.

03

Which is the better long-term investment — GKOS or EW or MDT or ATRC?

Over the past 5 years, Glaukos Corporation (GKOS) delivered a total return of +61.

5%, compared to -64. 2% for AtriCure, Inc. (ATRC). Over 10 years, the gap is even starker: GKOS returned +457. 1% versus MDT's +26. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — GKOS or EW or MDT or ATRC?

By beta (market sensitivity over 5 years), Medtronic plc (MDT) is the lower-risk stock at 0.

47β versus Glaukos Corporation's 1. 20β — meaning GKOS is approximately 158% more volatile than MDT relative to the S&P 500. On balance sheet safety, Edwards Lifesciences Corporation (EW) carries a lower debt/equity ratio of 7% versus 59% for Medtronic plc — giving it more financial flexibility in a downturn.

05

Which is growing faster — GKOS or EW or MDT or ATRC?

By revenue growth (latest reported year), Glaukos Corporation (GKOS) is pulling ahead at 32.

3% versus 3. 6% for Medtronic plc (MDT). On earnings-per-share growth, the picture is similar: AtriCure, Inc. grew EPS 74. 7% year-over-year, compared to -73. 7% for Edwards Lifesciences Corporation. Over a 3-year CAGR, GKOS leads at 21. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — GKOS or EW or MDT or ATRC?

Edwards Lifesciences Corporation (EW) is the more profitable company, earning 17.

7% net margin versus -37. 0% for Glaukos Corporation — meaning it keeps 17. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: EW leads at 27. 0% versus -17. 1% for GKOS. At the gross margin level — before operating expenses — EW leads at 78. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is GKOS or EW or MDT or ATRC more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Edwards Lifesciences Corporation (EW) is the more undervalued stock at a PEG of 3. 89x versus Medtronic plc's 36. 00x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Medtronic plc (MDT) trades at 14. 1x forward P/E versus 370. 7x for AtriCure, Inc. — 356. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ATRC: 82. 3% to $50. 67.

08

Which pays a better dividend — GKOS or EW or MDT or ATRC?

In this comparison, MDT (3.

6% yield) pays a dividend. GKOS, EW, ATRC do not pay a meaningful dividend and should not be held primarily for income.

09

Is GKOS or EW or MDT or ATRC better for a retirement portfolio?

For long-horizon retirement investors, Medtronic plc (MDT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

47), 3. 6% yield). Both have compounded well over 10 years (MDT: +26. 5%, ATRC: +95. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between GKOS and EW and MDT and ATRC?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: GKOS is a small-cap high-growth stock; EW is a mid-cap quality compounder stock; MDT is a mid-cap income-oriented stock; ATRC is a small-cap quality compounder stock. MDT pays a dividend while GKOS, EW, ATRC do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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GKOS

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 20%
  • Gross Margin > 46%
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EW

Steady Growth Compounder

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 6%
  • Net Margin > 10%
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MDT

Income & Dividend Stock

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 7%
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ATRC

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 7%
  • Gross Margin > 45%
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Beat Both

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Revenue Growth>
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(GKOS: 41.2% · EW: 13.3%)

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