Biotechnology
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GMAB vs REGN vs INCY vs ABBV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
GMAB vs REGN vs INCY vs ABBV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General |
| Market Cap | $16.67B | $73.68B | $19.53B | $358.42B |
| Revenue (TTM) | $8.65B | $14.92B | $5.36B | $61.16B |
| Net Income (TTM) | $2.76B | $4.42B | $1.43B | $4.23B |
| Gross Margin | 93.7% | 84.5% | 91.9% | 70.2% |
| Operating Margin | 36.6% | 24.3% | 26.8% | 26.7% |
| Forward P/E | 23.3x | 15.3x | 13.1x | 14.3x |
| Total Debt | $5.43B | $2.71B | $69M | $69.07B |
| Cash & Equiv. | $1.71B | $3.12B | $3.10B | $5.23B |
GMAB vs REGN vs INCY vs ABBV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Genmab A/S (GMAB) | 100 | 88.8 | -11.2% |
| Regeneron Pharmaceu… (REGN) | 100 | 115.7 | +15.7% |
| Incyte Corporation (INCY) | 100 | 95.9 | -4.1% |
| AbbVie Inc. (ABBV) | 100 | 218.7 | +118.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: GMAB vs REGN vs INCY vs ABBV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
GMAB is the clearest fit if your priority is valuation efficiency.
- PEG 0.80 vs REGN's 2.43
- 31.8% margin vs ABBV's 6.9%
REGN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
INCY carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 21.2%, EPS growth 41.7%, 3Y rev CAGR 14.8%
- 21.2% revenue growth vs GMAB's -82.7%
- Lower P/E (13.1x vs 14.3x)
- +64.2% vs ABBV's +11.3%
ABBV is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- 295.5% 10Y total return vs REGN's 90.0%
- Beta 0.34, yield 3.2%, current ratio 0.67x
- Beta 0.34 vs GMAB's 0.94
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 21.2% revenue growth vs GMAB's -82.7% | |
| Value | Lower P/E (13.1x vs 14.3x) | |
| Quality / Margins | 31.8% margin vs ABBV's 6.9% | |
| Stability / Safety | Beta 0.34 vs GMAB's 0.94 | |
| Dividends | 3.2% yield, 13-year raise streak, vs REGN's 0.5%, (2 stocks pay no dividend) | |
| Momentum (1Y) | +64.2% vs ABBV's +11.3% | |
| Efficiency (ROA) | 21.7% ROA vs ABBV's 3.1%, ROIC 51.1% vs 23.9% |
GMAB vs REGN vs INCY vs ABBV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
GMAB vs REGN vs INCY vs ABBV — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INCY leads in 2 of 6 categories
ABBV leads 2 • GMAB leads 1 • REGN leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
GMAB leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV is the larger business by revenue, generating $61.2B annually — 11.4x INCY's $5.4B. GMAB is the more profitable business, keeping 31.8% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, INCY holds the edge at +20.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $8.7B | $14.9B | $5.4B | $61.2B |
| EBITDAEarnings before interest/tax | $3.3B | $4.2B | $1.5B | $24.5B |
| Net IncomeAfter-tax profit | $2.8B | $4.4B | $1.4B | $4.2B |
| Free Cash FlowCash after capex | $2.9B | $4.2B | $1.5B | $18.7B |
| Gross MarginGross profit ÷ Revenue | +93.7% | +84.5% | +91.9% | +70.2% |
| Operating MarginEBIT ÷ Revenue | +36.6% | +24.3% | +26.8% | +26.7% |
| Net MarginNet income ÷ Revenue | +31.8% | +29.6% | +26.7% | +6.9% |
| FCF MarginFCF ÷ Revenue | +33.5% | +27.9% | +27.1% | +30.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | -83.6% | +19.0% | +20.9% | +10.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -99.2% | -7.2% | +83.8% | +57.4% |
Valuation Metrics
INCY leads this category, winning 5 of 7 comparable metrics.
Valuation Metrics
At 15.3x trailing earnings, INCY trades at a 82% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), GMAB offers better value at 0.80x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $16.7B | $73.7B | $19.5B | $358.4B |
| Enterprise ValueMkt cap + debt − cash | $20.4B | $73.3B | $16.5B | $422.3B |
| Trailing P/EPrice ÷ TTM EPS | 17.57x | 17.09x | 15.25x | 85.50x |
| Forward P/EPrice ÷ next-FY EPS est. | 23.33x | 15.35x | 13.06x | 14.28x |
| PEG RatioP/E ÷ EPS growth rate | 0.80x | 2.70x | — | — |
| EV / EBITDAEnterprise value multiple | 15.42x | 17.78x | 11.49x | 14.96x |
| Price / SalesMarket cap ÷ Revenue | 4.48x | 5.14x | 3.80x | 5.86x |
| Price / BookPrice ÷ Book value/share | 2.91x | 2.46x | 3.80x | — |
| Price / FCFMarket cap ÷ FCF | 14.50x | 18.06x | 14.42x | 20.12x |
Profitability & Efficiency
INCY leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $14 for GMAB. INCY carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to GMAB's 0.93x. On the Piotroski fundamental quality scale (0–9), INCY scores 7/9 vs GMAB's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +14.0% | +14.3% | +29.3% | +62.1% |
| ROA (TTM)Return on assets | +10.8% | +11.1% | +21.7% | +3.1% |
| ROICReturn on invested capital | +5.0% | +8.9% | +51.1% | +23.9% |
| ROCEReturn on capital employed | +4.8% | +10.2% | +29.0% | +21.5% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 | 7 | 6 |
| Debt / EquityFinancial leverage | 0.93x | 0.09x | 0.01x | — |
| Net DebtTotal debt minus cash | $3.7B | -$412M | -$3.0B | $63.8B |
| Cash & Equiv.Liquid assets | $1.7B | $3.1B | $3.1B | $5.2B |
| Total DebtShort + long-term debt | $5.4B | $2.7B | $69M | $69.1B |
| Interest CoverageEBIT ÷ Interest expense | 34.10x | 108.44x | 759.79x | 3.28x |
Total Returns (Dividends Reinvested)
ABBV leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $7,235 for GMAB. Over the past 12 months, INCY leads with a +64.2% total return vs ABBV's +11.3%. The 3-year compound annual growth rate (CAGR) favors ABBV at 14.6% vs GMAB's -12.5% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -15.0% | -8.5% | -3.6% | -10.1% |
| 1-Year ReturnPast 12 months | +31.4% | +27.1% | +64.2% | +11.3% |
| 3-Year ReturnCumulative with dividends | -33.0% | -5.1% | +48.6% | +50.4% |
| 5-Year ReturnCumulative with dividends | -27.6% | +43.6% | +18.2% | +101.3% |
| 10-Year ReturnCumulative with dividends | +78.3% | +90.0% | +34.2% | +295.5% |
| CAGR (3Y)Annualised 3-year return | -12.5% | -1.7% | +14.1% | +14.6% |
Risk & Volatility
Evenly matched — INCY and ABBV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than GMAB's 0.94 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INCY currently trades 87.1% from its 52-week high vs GMAB's 76.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.94x | 0.81x | 0.87x | 0.34x |
| 52-Week HighHighest price in past year | $35.43 | $821.11 | $112.29 | $244.81 |
| 52-Week LowLowest price in past year | $18.89 | $476.49 | $57.77 | $176.57 |
| % of 52W HighCurrent price vs 52-week peak | +76.4% | +86.4% | +87.1% | +82.8% |
| RSI (14)Momentum oscillator 0–100 | 54.9 | 44.9 | 59.4 | 46.8 |
| Avg Volume (50D)Average daily shares traded | 1.6M | 631K | 1.4M | 5.8M |
Analyst Outlook
ABBV leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: GMAB as "Buy", REGN as "Buy", INCY as "Buy", ABBV as "Buy". Consensus price targets imply 47.5% upside for GMAB (target: $40) vs 12.0% for INCY (target: $110). For income investors, ABBV offers the higher dividend yield at 3.24% vs REGN's 0.48%.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $39.90 | $865.68 | $109.50 | $256.64 |
| # AnalystsCovering analysts | 17 | 48 | 44 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% | — | +3.2% |
| Dividend StreakConsecutive years of raises | — | 1 | — | 13 |
| Dividend / ShareAnnual DPS | — | $3.41 | — | $6.57 |
| Buyback YieldShare repurchases ÷ mkt cap | +2.6% | +5.4% | +0.1% | +0.3% |
INCY leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). ABBV leads in 2 (Total Returns, Analyst Outlook). 1 tied.
GMAB vs REGN vs INCY vs ABBV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is GMAB or REGN or INCY or ABBV a better buy right now?
For growth investors, Incyte Corporation (INCY) is the stronger pick with 21.
2% revenue growth year-over-year, versus -82. 7% for Genmab A/S (GMAB). Incyte Corporation (INCY) offers the better valuation at 15. 3x trailing P/E (13. 1x forward), making it the more compelling value choice. Analysts rate Genmab A/S (GMAB) a "Buy" — based on 17 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — GMAB or REGN or INCY or ABBV?
On trailing P/E, Incyte Corporation (INCY) is the cheapest at 15.
3x versus AbbVie Inc. at 85. 5x. On forward P/E, Incyte Corporation is actually cheaper at 13. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Genmab A/S wins at 0. 80x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — GMAB or REGN or INCY or ABBV?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -27. 6% for Genmab A/S (GMAB). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus INCY's +34. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — GMAB or REGN or INCY or ABBV?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus Genmab A/S's 0. 94β — meaning GMAB is approximately 177% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Incyte Corporation (INCY) carries a lower debt/equity ratio of 1% versus 93% for Genmab A/S — giving it more financial flexibility in a downturn.
05Which is growing faster — GMAB or REGN or INCY or ABBV?
By revenue growth (latest reported year), Incyte Corporation (INCY) is pulling ahead at 21.
2% versus -82. 7% for Genmab A/S (GMAB). On earnings-per-share growth, the picture is similar: Incyte Corporation grew EPS 41. 7% year-over-year, compared to -87. 3% for Genmab A/S. Over a 3-year CAGR, INCY leads at 14. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — GMAB or REGN or INCY or ABBV?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus 6. 9% for AbbVie Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: GMAB leads at 33. 6% versus 24. 9% for REGN. At the gross margin level — before operating expenses — GMAB leads at 91. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is GMAB or REGN or INCY or ABBV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Genmab A/S (GMAB) is the more undervalued stock at a PEG of 0. 80x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Incyte Corporation (INCY) trades at 13. 1x forward P/E versus 23. 3x for Genmab A/S — 10. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for GMAB: 47. 5% to $39. 90.
08Which pays a better dividend — GMAB or REGN or INCY or ABBV?
In this comparison, ABBV (3.
2% yield), REGN (0. 5% yield) pay a dividend. GMAB, INCY do not pay a meaningful dividend and should not be held primarily for income.
09Is GMAB or REGN or INCY or ABBV better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, GMAB: +78. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between GMAB and REGN and INCY and ABBV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: GMAB is a mid-cap deep-value stock; REGN is a mid-cap deep-value stock; INCY is a mid-cap high-growth stock; ABBV is a large-cap income-oriented stock. ABBV pays a dividend while GMAB, REGN, INCY do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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