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Stock Comparison

HRTX vs DBVT vs PRGO vs IQV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
HRTX
Heron Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$228M
5Y Perf.-93.4%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1690.08T
5Y Perf.-59.3%
PRGO
Perrigo Company plc

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • IE
Market Cap$1.62B
5Y Perf.-78.6%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$30.33B
5Y Perf.+19.5%

HRTX vs DBVT vs PRGO vs IQV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
HRTX logoHRTX
DBVT logoDBVT
PRGO logoPRGO
IQV logoIQV
IndustryBiotechnologyBiotechnologyDrug Manufacturers - Specialty & GenericMedical - Diagnostics & Research
Market Cap$228M$1690.08T$1.62B$30.33B
Revenue (TTM)$155M$0.00$4.18B$16.63B
Net Income (TTM)$-20M$-168M$-1.82B$1.39B
Gross Margin73.3%34.2%26.1%
Operating Margin-1.6%-4.1%13.9%
Forward P/E5.5x14.0x
Total Debt$141M$22M$3.97B$16.17B
Cash & Equiv.$29M$194M$532M$1.98B

HRTX vs DBVT vs PRGO vs IQVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

HRTX
DBVT
PRGO
IQV
StockMay 20May 26Return
Heron Therapeutics,… (HRTX)1006.6-93.4%
DBV Technologies S.… (DBVT)10040.7-59.3%
Perrigo Company plc (PRGO)10021.4-78.6%
IQVIA Holdings Inc. (IQV)100119.5+19.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: HRTX vs DBVT vs PRGO vs IQV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: PRGO leads in 3 of 7 categories, making it the strongest pick for valuation and capital efficiency and capital preservation and lower volatility. IQVIA Holdings Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. HRTX and DBVT also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
HRTX
Heron Therapeutics, Inc.
The Growth Play

HRTX is the clearest fit if your priority is growth exposure.

  • Rev growth 7.4%, EPS growth -34.7%, 3Y rev CAGR 12.9%
  • 7.4% revenue growth vs DBVT's -100.0%
Best for: growth exposure
DBVT
DBV Technologies S.A.
The Defensive Pick

DBVT is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 1.26, Low D/E 12.8%, current ratio 3.67x
  • +100.5% vs PRGO's -52.0%
Best for: sleep-well-at-night
PRGO
Perrigo Company plc
The Income Pick

PRGO carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • Dividend streak 10 yrs, beta 1.21, yield 9.8%
  • Beta 1.21, yield 9.8%, current ratio 2.76x
  • Lower P/E (5.5x vs 14.0x)
  • Beta 1.21 vs HRTX's 1.81, lower leverage
Best for: income & stability and defensive
IQV
IQVIA Holdings Inc.
The Long-Run Compounder

IQV is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 166.6% 10Y total return vs PRGO's -77.7%
  • 8.3% margin vs PRGO's -43.5%
  • 4.7% ROA vs DBVT's -89.0%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthHRTX logoHRTX7.4% revenue growth vs DBVT's -100.0%
ValuePRGO logoPRGOLower P/E (5.5x vs 14.0x)
Quality / MarginsIQV logoIQV8.3% margin vs PRGO's -43.5%
Stability / SafetyPRGO logoPRGOBeta 1.21 vs HRTX's 1.81, lower leverage
DividendsPRGO logoPRGO9.8% yield; 10-year raise streak; the other 3 pay no meaningful dividend
Momentum (1Y)DBVT logoDBVT+100.5% vs PRGO's -52.0%
Efficiency (ROA)IQV logoIQV4.7% ROA vs DBVT's -89.0%

HRTX vs DBVT vs PRGO vs IQV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

HRTXHeron Therapeutics, Inc.
FY 2025
C I N V A N T I
67.5%$97M
Z Y N R E L E F
26.6%$38M
S U S T O L
5.9%$9M
DBVTDBV Technologies S.A.

Segment breakdown not available.

PRGOPerrigo Company plc
FY 2025
Consumer Self-Care Americas
60.8%$2.6B
Consumer Self-Care International
39.2%$1.7B
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M

HRTX vs DBVT vs PRGO vs IQV — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLPRGOLAGGINGHRTX

Income & Cash Flow (Last 12 Months)

IQV leads this category, winning 4 of 6 comparable metrics.

IQV and DBVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. IQV is the more profitable business, keeping 8.3% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, IQV holds the edge at +8.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricHRTX logoHRTXHeron Therapeutic…DBVT logoDBVTDBV Technologies …PRGO logoPRGOPerrigo Company p…IQV logoIQVIQVIA Holdings In…
RevenueTrailing 12 months$155M$0$4.2B$16.6B
EBITDAEarnings before interest/tax$401,000-$112M$58M$3.5B
Net IncomeAfter-tax profit-$20M-$168M-$1.8B$1.4B
Free Cash FlowCash after capex-$28M-$151M$108M$2.7B
Gross MarginGross profit ÷ Revenue+73.3%+34.2%+26.1%
Operating MarginEBIT ÷ Revenue-1.6%-4.1%+13.9%
Net MarginNet income ÷ Revenue-13.0%-43.5%+8.3%
FCF MarginFCF ÷ Revenue-18.0%+2.6%+16.1%
Rev. Growth (YoY)Latest quarter vs prior year-0.5%-7.2%+8.4%
EPS Growth (YoY)Latest quarter vs prior year-183.7%+91.5%-56.4%+15.0%
IQV leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

PRGO leads this category, winning 5 of 6 comparable metrics.

On an enterprise value basis, PRGO's 7.4x EV/EBITDA is more attractive than IQV's 13.0x.

MetricHRTX logoHRTXHeron Therapeutic…DBVT logoDBVTDBV Technologies …PRGO logoPRGOPerrigo Company p…IQV logoIQVIQVIA Holdings In…
Market CapShares × price$228M$1690.08T$1.6B$30.3B
Enterprise ValueMkt cap + debt − cash$340M$1690.08T$5.1B$44.5B
Trailing P/EPrice ÷ TTM EPS-10.08x-0.75x-1.14x22.79x
Forward P/EPrice ÷ next-FY EPS est.5.53x13.96x
PEG RatioP/E ÷ EPS growth rate0.56x
EV / EBITDAEnterprise value multiple7.43x12.98x
Price / SalesMarket cap ÷ Revenue1.47x0.38x1.86x
Price / BookPrice ÷ Book value/share14.07x0.65x0.55x4.68x
Price / FCFMarket cap ÷ FCF11.17x14.79x
PRGO leads this category, winning 5 of 6 comparable metrics.

Profitability & Efficiency

IQV leads this category, winning 6 of 9 comparable metrics.

IQV delivers a 22.1% return on equity — every $100 of shareholder capital generates $22 in annual profit, vs $-141 for HRTX. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to HRTX's 9.81x. On the Piotroski fundamental quality scale (0–9), DBVT scores 4/9 vs HRTX's 3/9, reflecting mixed financial health.

MetricHRTX logoHRTXHeron Therapeutic…DBVT logoDBVTDBV Technologies …PRGO logoPRGOPerrigo Company p…IQV logoIQVIQVIA Holdings In…
ROE (TTM)Return on equity-140.9%-130.2%-50.7%+22.1%
ROA (TTM)Return on assets-7.9%-89.0%-19.8%+4.7%
ROICReturn on invested capital-1.6%+3.7%+8.7%
ROCEReturn on capital employed-1.7%-145.7%+4.3%+11.0%
Piotroski ScoreFundamental quality 0–93444
Debt / EquityFinancial leverage9.81x0.13x1.35x2.44x
Net DebtTotal debt minus cash$112M-$172M$3.4B$14.2B
Cash & Equiv.Liquid assets$29M$194M$532M$2.0B
Total DebtShort + long-term debt$141M$22M$4.0B$16.2B
Interest CoverageEBIT ÷ Interest expense-2.97x-189.82x-7.20x3.10x
IQV leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

DBVT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IQV five years ago would be worth $7,720 today (with dividends reinvested), compared to $689 for HRTX. Over the past 12 months, DBVT leads with a +100.5% total return vs PRGO's -52.0%. The 3-year compound annual growth rate (CAGR) favors DBVT at 5.7% vs PRGO's -25.2% — a key indicator of consistent wealth creation.

MetricHRTX logoHRTXHeron Therapeutic…DBVT logoDBVTDBV Technologies …PRGO logoPRGOPerrigo Company p…IQV logoIQVIQVIA Holdings In…
YTD ReturnYear-to-date-4.0%+3.6%-13.6%-20.7%
1-Year ReturnPast 12 months-44.2%+100.5%-52.0%+16.6%
3-Year ReturnCumulative with dividends-50.4%+18.1%-58.1%-5.9%
5-Year ReturnCumulative with dividends-93.1%-68.3%-60.3%-22.8%
10-Year ReturnCumulative with dividends-93.0%-87.1%-77.7%+166.6%
CAGR (3Y)Annualised 3-year return-20.8%+5.7%-25.2%-2.0%
DBVT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — DBVT and PRGO each lead in 1 of 2 comparable metrics.

PRGO is the less volatile stock with a 1.21 beta — it tends to amplify market swings less than HRTX's 1.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DBVT currently trades 75.3% from its 52-week high vs PRGO's 41.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricHRTX logoHRTXHeron Therapeutic…DBVT logoDBVTDBV Technologies …PRGO logoPRGOPerrigo Company p…IQV logoIQVIQVIA Holdings In…
Beta (5Y)Sensitivity to S&P 5001.81x1.26x1.21x1.32x
52-Week HighHighest price in past year$2.32$26.18$28.44$247.05
52-Week LowLowest price in past year$0.74$7.53$9.23$134.65
% of 52W HighCurrent price vs 52-week peak+52.2%+75.3%+41.2%+72.3%
RSI (14)Momentum oscillator 0–10064.247.453.160.3
Avg Volume (50D)Average daily shares traded2.0M252K3.3M1.5M
Evenly matched — DBVT and PRGO each lead in 1 of 2 comparable metrics.

Analyst Outlook

PRGO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: HRTX as "Buy", DBVT as "Buy", PRGO as "Hold", IQV as "Buy". Consensus price targets imply 451.2% upside for HRTX (target: $7) vs 25.2% for IQV (target: $224). PRGO is the only dividend payer here at 9.82% yield — a key consideration for income-focused portfolios.

MetricHRTX logoHRTXHeron Therapeutic…DBVT logoDBVTDBV Technologies …PRGO logoPRGOPerrigo Company p…IQV logoIQVIQVIA Holdings In…
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$6.67$46.33$36.20$223.75
# AnalystsCovering analysts19153644
Dividend YieldAnnual dividend ÷ price+9.8%
Dividend StreakConsecutive years of raises0102
Dividend / ShareAnnual DPS$1.15
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+4.1%
PRGO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

IQV leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRGO leads in 2 (Valuation Metrics, Analyst Outlook). 1 tied.

Best OverallPerrigo Company plc (PRGO)Leads 2 of 6 categories
Loading custom metrics...

HRTX vs DBVT vs PRGO vs IQV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is HRTX or DBVT or PRGO or IQV a better buy right now?

For growth investors, Heron Therapeutics, Inc.

(HRTX) is the stronger pick with 7. 4% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). IQVIA Holdings Inc. (IQV) offers the better valuation at 22. 8x trailing P/E (14. 0x forward), making it the more compelling value choice. Analysts rate Heron Therapeutics, Inc. (HRTX) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — HRTX or DBVT or PRGO or IQV?

On forward P/E, Perrigo Company plc is actually cheaper at 5.

5x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — HRTX or DBVT or PRGO or IQV?

Over the past 5 years, IQVIA Holdings Inc.

(IQV) delivered a total return of -22. 8%, compared to -93. 1% for Heron Therapeutics, Inc. (HRTX). Over 10 years, the gap is even starker: IQV returned +166. 6% versus HRTX's -93. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — HRTX or DBVT or PRGO or IQV?

By beta (market sensitivity over 5 years), Perrigo Company plc (PRGO) is the lower-risk stock at 1.

21β versus Heron Therapeutics, Inc. 's 1. 81β — meaning HRTX is approximately 49% more volatile than PRGO relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 10% for Heron Therapeutics, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — HRTX or DBVT or PRGO or IQV?

By revenue growth (latest reported year), Heron Therapeutics, Inc.

(HRTX) is pulling ahead at 7. 4% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: IQVIA Holdings Inc. grew EPS 4. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, HRTX leads at 12. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — HRTX or DBVT or PRGO or IQV?

IQVIA Holdings Inc.

(IQV) is the more profitable company, earning 8. 3% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 8. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IQV leads at 14. 0% versus -1. 6% for HRTX. At the gross margin level — before operating expenses — HRTX leads at 73. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is HRTX or DBVT or PRGO or IQV more undervalued right now?

On forward earnings alone, Perrigo Company plc (PRGO) trades at 5.

5x forward P/E versus 14. 0x for IQVIA Holdings Inc. — 8. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for HRTX: 451. 2% to $6. 67.

08

Which pays a better dividend — HRTX or DBVT or PRGO or IQV?

In this comparison, PRGO (9.

8% yield) pays a dividend. HRTX, DBVT, IQV do not pay a meaningful dividend and should not be held primarily for income.

09

Is HRTX or DBVT or PRGO or IQV better for a retirement portfolio?

For long-horizon retirement investors, Perrigo Company plc (PRGO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.

21), 9. 8% yield). Heron Therapeutics, Inc. (HRTX) carries a higher beta of 1. 81 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (PRGO: -77. 7%, HRTX: -93. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between HRTX and DBVT and PRGO and IQV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: HRTX is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; PRGO is a small-cap income-oriented stock; IQV is a mid-cap quality compounder stock. PRGO pays a dividend while HRTX, DBVT, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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HRTX

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  • Gross Margin > 20%
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