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Stock Comparison

HUMA vs AORT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
HUMA
Humacyte, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$140M
5Y Perf.-89.4%
AORT
Artivion, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$1.72B
5Y Perf.+49.9%

HUMA vs AORT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
HUMA logoHUMA
AORT logoAORT
IndustryBiotechnologyMedical - Devices
Market Cap$140M$1.72B
Revenue (TTM)$9M$459M
Net Income (TTM)$-37M$12M
Gross Margin9.9%63.8%
Operating Margin-12.0%7.4%
Forward P/E98.7x
Total Debt$17M$292M
Cash & Equiv.$45M$65M

HUMA vs AORTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

HUMA
AORT
StockDec 20May 26Return
Humacyte, Inc. (HUMA)10010.6-89.4%
Artivion, Inc. (AORT)100149.9+49.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: HUMA vs AORT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: AORT leads in 4 of 6 categories, making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Humacyte, Inc. is the stronger pick specifically for growth and revenue expansion. As sector peers, any of these can serve as alternatives in the same allocation.
HUMA
Humacyte, Inc.
The Growth Leader

HUMA is the clearest fit if your priority is growth.

  • 79.5% revenue growth vs AORT's 13.6%
Best for: growth
AORT
Artivion, Inc.
The Income Pick

AORT carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 4 yrs, beta 0.63
  • Rev growth 13.6%, EPS growth 165.6%, 3Y rev CAGR 12.0%
  • 188.9% 10Y total return vs HUMA's -88.8%
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthHUMA logoHUMA79.5% revenue growth vs AORT's 13.6%
Quality / MarginsAORT logoAORT2.5% margin vs HUMA's -420.2%
Stability / SafetyAORT logoAORTBeta 0.63 vs HUMA's 3.27
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)AORT logoAORT+24.7% vs HUMA's -11.5%
Efficiency (ROA)AORT logoAORT1.3% ROA vs HUMA's -40.4%

HUMA vs AORT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

HUMAHumacyte, Inc.

Segment breakdown not available.

AORTArtivion, Inc.
FY 2025
Aortic Stent Grafts
36.1%$159M
On X
23.1%$102M
Preservation Services
21.6%$96M
Surgical Sealants
17.4%$77M
Other Products
1.8%$8M

HUMA vs AORT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLAORTLAGGINGHUMA

Income & Cash Flow (Last 12 Months)

AORT leads this category, winning 5 of 5 comparable metrics.

AORT is the larger business by revenue, generating $459M annually — 52.1x HUMA's $9M. AORT is the more profitable business, keeping 2.5% of every revenue dollar as net income compared to HUMA's -4.2%.

MetricHUMA logoHUMAHumacyte, Inc.AORT logoAORTArtivion, Inc.
RevenueTrailing 12 months$9M$459M
EBITDAEarnings before interest/tax-$98M$51M
Net IncomeAfter-tax profit-$37M$12M
Free Cash FlowCash after capex-$106M$13M
Gross MarginGross profit ÷ Revenue+9.9%+63.8%
Operating MarginEBIT ÷ Revenue-12.0%+7.4%
Net MarginNet income ÷ Revenue-4.2%+2.5%
FCF MarginFCF ÷ Revenue-12.1%+2.8%
Rev. Growth (YoY)Latest quarter vs prior year+17.5%
EPS Growth (YoY)Latest quarter vs prior year+66.7%+3.5%
AORT leads this category, winning 5 of 5 comparable metrics.

Valuation Metrics

HUMA leads this category, winning 1 of 1 comparable metric.
MetricHUMA logoHUMAHumacyte, Inc.AORT logoAORTArtivion, Inc.
Market CapShares × price$140M$1.7B
Enterprise ValueMkt cap + debt − cash$112M$1.9B
Trailing P/EPrice ÷ TTM EPS-0.86x168.52x
Forward P/EPrice ÷ next-FY EPS est.98.69x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple39.50x
Price / SalesMarket cap ÷ Revenue3.89x
Price / BookPrice ÷ Book value/share3.72x
Price / FCFMarket cap ÷ FCF
HUMA leads this category, winning 1 of 1 comparable metric.

Profitability & Efficiency

AORT leads this category, winning 4 of 6 comparable metrics.

On the Piotroski fundamental quality scale (0–9), AORT scores 6/9 vs HUMA's 2/9, reflecting solid financial health.

MetricHUMA logoHUMAHumacyte, Inc.AORT logoAORTArtivion, Inc.
ROE (TTM)Return on equity+2.7%
ROA (TTM)Return on assets-40.4%+1.3%
ROICReturn on invested capital+3.2%
ROCEReturn on capital employed-100.5%+3.6%
Piotroski ScoreFundamental quality 0–926
Debt / EquityFinancial leverage0.65x
Net DebtTotal debt minus cash-$28M$227M
Cash & Equiv.Liquid assets$45M$65M
Total DebtShort + long-term debt$17M$292M
Interest CoverageEBIT ÷ Interest expense-2.47x1.28x
AORT leads this category, winning 4 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

AORT leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in AORT five years ago would be worth $11,543 today (with dividends reinvested), compared to $1,080 for HUMA. Over the past 12 months, AORT leads with a +24.7% total return vs HUMA's -11.5%. The 3-year compound annual growth rate (CAGR) favors AORT at 34.3% vs HUMA's -39.9% — a key indicator of consistent wealth creation.

MetricHUMA logoHUMAHumacyte, Inc.AORT logoAORTArtivion, Inc.
YTD ReturnYear-to-date+10.8%-20.4%
1-Year ReturnPast 12 months-11.5%+24.7%
3-Year ReturnCumulative with dividends-78.3%+142.2%
5-Year ReturnCumulative with dividends-89.2%+15.4%
10-Year ReturnCumulative with dividends-88.8%+188.9%
CAGR (3Y)Annualised 3-year return-39.9%+34.3%
AORT leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

AORT leads this category, winning 2 of 2 comparable metrics.

AORT is the less volatile stock with a 0.63 beta — it tends to amplify market swings less than HUMA's 3.27 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. AORT currently trades 73.3% from its 52-week high vs HUMA's 36.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricHUMA logoHUMAHumacyte, Inc.AORT logoAORTArtivion, Inc.
Beta (5Y)Sensitivity to S&P 5003.27x0.63x
52-Week HighHighest price in past year$2.93$48.25
52-Week LowLowest price in past year$0.55$26.84
% of 52W HighCurrent price vs 52-week peak+36.9%+73.3%
RSI (14)Momentum oscillator 0–10065.942.1
Avg Volume (50D)Average daily shares traded6.7M385K
AORT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates HUMA as "Buy" and AORT as "Buy". Consensus price targets imply 177.8% upside for HUMA (target: $3) vs 46.9% for AORT (target: $52).

MetricHUMA logoHUMAHumacyte, Inc.AORT logoAORTArtivion, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$3.00$52.00
# AnalystsCovering analysts1112
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises4
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

AORT leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). HUMA leads in 1 (Valuation Metrics).

Best OverallArtivion, Inc. (AORT)Leads 4 of 6 categories
Loading custom metrics...

HUMA vs AORT: Frequently Asked Questions

9 questions · data-driven answers · updated daily

01

Is HUMA or AORT a better buy right now?

Artivion, Inc.

(AORT) offers the better valuation at 168. 5x trailing P/E (98. 7x forward), making it the more compelling value choice. Analysts rate Humacyte, Inc. (HUMA) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — HUMA or AORT?

Over the past 5 years, Artivion, Inc.

(AORT) delivered a total return of +15. 4%, compared to -89. 2% for Humacyte, Inc. (HUMA). Over 10 years, the gap is even starker: AORT returned +188. 9% versus HUMA's -88. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — HUMA or AORT?

By beta (market sensitivity over 5 years), Artivion, Inc.

(AORT) is the lower-risk stock at 0. 63β versus Humacyte, Inc. 's 3. 27β — meaning HUMA is approximately 420% more volatile than AORT relative to the S&P 500.

04

Which is growing faster — HUMA or AORT?

On earnings-per-share growth, the picture is similar: Artivion, Inc.

grew EPS 165. 6% year-over-year, compared to -17. 8% for Humacyte, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — HUMA or AORT?

Artivion, Inc.

(AORT) is the more profitable company, earning 2. 2% net margin versus -420. 2% for Humacyte, Inc. — meaning it keeps 2. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: AORT leads at 6. 1% versus -1197. 7% for HUMA. At the gross margin level — before operating expenses — AORT leads at 61. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is HUMA or AORT more undervalued right now?

Analyst consensus price targets imply the most upside for HUMA: 177.

8% to $3. 00.

07

Which pays a better dividend — HUMA or AORT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is HUMA or AORT better for a retirement portfolio?

For long-horizon retirement investors, Artivion, Inc.

(AORT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 63), +188. 9% 10Y return). Humacyte, Inc. (HUMA) carries a higher beta of 3. 27 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (AORT: +188. 9%, HUMA: -88. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between HUMA and AORT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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HUMA

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  • Market Cap > $100B
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 8%
  • Gross Margin > 38%
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