Biotechnology
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4 / 10Stock Comparison
IBIO vs ADMA vs HALO vs TECH
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
IBIO vs ADMA vs HALO vs TECH — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $27M | $1.89B | $7.55B | $7.57B |
| Revenue (TTM) | $300K | $510M | $1.40B | $1.21B |
| Net Income (TTM) | $-25M | $165M | $317M | $110M |
| Gross Margin | -76.7% | 61.3% | 81.9% | 65.0% |
| Operating Margin | -76.6% | 42.1% | 58.4% | 12.7% |
| Forward P/E | — | 9.7x | 8.0x | 24.9x |
| Total Debt | $4M | $80M | $0.00 | $444M |
| Cash & Equiv. | $9M | $88M | $134M | $162M |
IBIO vs ADMA vs HALO vs TECH — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| iBio, Inc. (IBIO) | 100 | 0.2 | -99.8% |
| ADMA Biologics, Inc. (ADMA) | 100 | 248.3 | +148.3% |
| Halozyme Therapeuti… (HALO) | 100 | 264.2 | +164.2% |
| Bio-Techne Corporat… (TECH) | 100 | 73.1 | -26.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IBIO vs ADMA vs HALO vs TECH
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IBIO has the current edge in this matchup, primarily because of its strength in growth exposure.
- Rev growth 77.8%, EPS growth 73.1%, 3Y rev CAGR -40.3%
- 77.8% revenue growth vs TECH's 5.2%
- +106.0% vs ADMA's -61.5%
ADMA is the #2 pick in this set and the best alternative if sleep-well-at-night is your priority.
- Lower volatility, beta 1.25, Low D/E 16.7%, current ratio 6.71x
- 32.4% margin vs IBIO's -82.5%
- 27.4% ROA vs IBIO's -57.9%, ROIC 36.0% vs -130.5%
HALO is the clearest fit if your priority is long-term compounding and defensive.
- 5.6% 10Y total return vs ADMA's 34.8%
- Beta 0.51, current ratio 4.66x
- Lower P/E (8.0x vs 24.9x)
- Beta 0.51 vs IBIO's 2.10
TECH is the clearest fit if your priority is income & stability.
- Dividend streak 3 yrs, beta 1.20, yield 0.7%
- 0.7% yield; 3-year raise streak; the other 3 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 77.8% revenue growth vs TECH's 5.2% | |
| Value | Lower P/E (8.0x vs 24.9x) | |
| Quality / Margins | 32.4% margin vs IBIO's -82.5% | |
| Stability / Safety | Beta 0.51 vs IBIO's 2.10 | |
| Dividends | 0.7% yield; 3-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +106.0% vs ADMA's -61.5% | |
| Efficiency (ROA) | 27.4% ROA vs IBIO's -57.9%, ROIC 36.0% vs -130.5% |
IBIO vs ADMA vs HALO vs TECH — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
IBIO vs ADMA vs HALO vs TECH — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
ADMA leads 1 • TECH leads 1 • IBIO leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HALO leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
HALO is the larger business by revenue, generating $1.4B annually — 4655.4x IBIO's $300,000. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to IBIO's -82.5%. On growth, HALO holds the edge at +51.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $300,000 | $510M | $1.4B | $1.2B |
| EBITDAEarnings before interest/tax | -$22M | $221M | $945M | $254M |
| Net IncomeAfter-tax profit | -$25M | $165M | $317M | $110M |
| Free Cash FlowCash after capex | -$19M | $108M | $645M | $270M |
| Gross MarginGross profit ÷ Revenue | -76.7% | +61.3% | +81.9% | +65.0% |
| Operating MarginEBIT ÷ Revenue | -76.6% | +42.1% | +58.4% | +12.7% |
| Net MarginNet income ÷ Revenue | -82.5% | +32.4% | +22.7% | +9.0% |
| FCF MarginFCF ÷ Revenue | -64.0% | +21.2% | +46.2% | +22.3% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | -0.3% | +51.6% | -1.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +81.1% | +72.7% | -2.1% | +128.6% |
Valuation Metrics
HALO leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
At 13.6x trailing earnings, ADMA trades at a 87% valuation discount to TECH's 105.2x P/E. On an enterprise value basis, HALO's 8.2x EV/EBITDA is more attractive than TECH's 37.0x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $27M | $1.9B | $7.6B | $7.6B |
| Enterprise ValueMkt cap + debt − cash | $22M | $1.9B | $7.4B | $7.9B |
| Trailing P/EPrice ÷ TTM EPS | -0.98x | 13.62x | 25.05x | 105.15x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 9.69x | 7.96x | 24.94x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.09x | — |
| EV / EBITDAEnterprise value multiple | — | 9.45x | 8.20x | 37.02x |
| Price / SalesMarket cap ÷ Revenue | 67.50x | 3.71x | 5.41x | 6.21x |
| Price / BookPrice ÷ Book value/share | 1.21x | 4.19x | 162.76x | 4.03x |
| Price / FCFMarket cap ÷ FCF | — | 68.06x | 11.72x | 29.52x |
Profitability & Efficiency
Evenly matched — ADMA and HALO each lead in 5 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-71 for IBIO. ADMA carries lower financial leverage with a 0.17x debt-to-equity ratio, signaling a more conservative balance sheet compared to IBIO's 0.24x. On the Piotroski fundamental quality scale (0–9), ADMA scores 5/9 vs IBIO's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -71.3% | +39.0% | +6.5% | +5.5% |
| ROA (TTM)Return on assets | -57.9% | +27.4% | +12.5% | +4.3% |
| ROICReturn on invested capital | -130.5% | +36.0% | +73.4% | +3.4% |
| ROCEReturn on capital employed | -88.6% | +38.8% | +38.2% | +4.2% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 5 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.24x | 0.17x | — | 0.23x |
| Net DebtTotal debt minus cash | -$5M | -$8M | -$134M | $282M |
| Cash & Equiv.Liquid assets | $9M | $88M | $134M | $162M |
| Total DebtShort + long-term debt | $4M | $80M | $0 | $444M |
| Interest CoverageEBIT ÷ Interest expense | -128.89x | 50.85x | 46.08x | 15.11x |
Total Returns (Dividends Reinvested)
ADMA leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ADMA five years ago would be worth $48,922 today (with dividends reinvested), compared to $21 for IBIO. Over the past 12 months, IBIO leads with a +106.0% total return vs ADMA's -61.5%. The 3-year compound annual growth rate (CAGR) favors ADMA at 32.7% vs IBIO's -57.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -15.3% | -54.3% | -8.8% | -18.8% |
| 1-Year ReturnPast 12 months | +106.0% | -61.5% | -5.3% | -2.2% |
| 3-Year ReturnCumulative with dividends | -92.1% | +133.4% | +111.8% | -40.0% |
| 5-Year ReturnCumulative with dividends | -99.8% | +389.2% | +39.1% | -51.0% |
| 10-Year ReturnCumulative with dividends | -100.0% | +34.8% | +559.7% | +102.6% |
| CAGR (3Y)Annualised 3-year return | -57.1% | +32.7% | +28.4% | -15.7% |
Risk & Volatility
HALO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
HALO is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than IBIO's 2.10 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. HALO currently trades 78.0% from its 52-week high vs ADMA's 35.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.10x | 1.25x | 0.51x | 1.20x |
| 52-Week HighHighest price in past year | $3.82 | $22.73 | $82.22 | $72.16 |
| 52-Week LowLowest price in past year | $0.56 | $7.21 | $47.50 | $45.12 |
| % of 52W HighCurrent price vs 52-week peak | +44.8% | +35.9% | +78.0% | +67.0% |
| RSI (14)Momentum oscillator 0–100 | 39.0 | 26.0 | 47.7 | 43.2 |
| Avg Volume (50D)Average daily shares traded | 976K | 7.4M | 1.4M | 2.4M |
Analyst Outlook
TECH leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ADMA as "Buy", HALO as "Buy", TECH as "Buy". Consensus price targets imply 157.0% upside for ADMA (target: $21) vs 17.9% for HALO (target: $76). TECH is the only dividend payer here at 0.65% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $21.00 | $75.60 | $61.33 |
| # AnalystsCovering analysts | — | 10 | 27 | 25 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +0.7% |
| Dividend StreakConsecutive years of raises | — | 1 | — | 3 |
| Dividend / ShareAnnual DPS | — | — | — | $0.32 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.7% | +4.5% | +3.6% |
HALO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). ADMA leads in 1 (Total Returns). 1 tied.
IBIO vs ADMA vs HALO vs TECH: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is IBIO or ADMA or HALO or TECH a better buy right now?
For growth investors, iBio, Inc.
(IBIO) is the stronger pick with 77. 8% revenue growth year-over-year, versus 5. 2% for Bio-Techne Corporation (TECH). ADMA Biologics, Inc. (ADMA) offers the better valuation at 13. 6x trailing P/E (9. 7x forward), making it the more compelling value choice. Analysts rate ADMA Biologics, Inc. (ADMA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — IBIO or ADMA or HALO or TECH?
On trailing P/E, ADMA Biologics, Inc.
(ADMA) is the cheapest at 13. 6x versus Bio-Techne Corporation at 105. 2x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 0x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — IBIO or ADMA or HALO or TECH?
Over the past 5 years, ADMA Biologics, Inc.
(ADMA) delivered a total return of +389. 2%, compared to -99. 8% for iBio, Inc. (IBIO). Over 10 years, the gap is even starker: HALO returned +559. 7% versus IBIO's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — IBIO or ADMA or HALO or TECH?
By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.
(HALO) is the lower-risk stock at 0. 51β versus iBio, Inc. 's 2. 10β — meaning IBIO is approximately 310% more volatile than HALO relative to the S&P 500. On balance sheet safety, ADMA Biologics, Inc. (ADMA) carries a lower debt/equity ratio of 17% versus 24% for iBio, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — IBIO or ADMA or HALO or TECH?
By revenue growth (latest reported year), iBio, Inc.
(IBIO) is pulling ahead at 77. 8% versus 5. 2% for Bio-Techne Corporation (TECH). On earnings-per-share growth, the picture is similar: iBio, Inc. grew EPS 73. 1% year-over-year, compared to -56. 2% for Bio-Techne Corporation. Over a 3-year CAGR, ADMA leads at 49. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — IBIO or ADMA or HALO or TECH?
ADMA Biologics, Inc.
(ADMA) is the more profitable company, earning 28. 8% net margin versus -45. 9% for iBio, Inc. — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -46. 5% for IBIO. At the gross margin level — before operating expenses — IBIO leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is IBIO or ADMA or HALO or TECH more undervalued right now?
On forward earnings alone, Halozyme Therapeutics, Inc.
(HALO) trades at 8. 0x forward P/E versus 24. 9x for Bio-Techne Corporation — 17. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 157. 0% to $21. 00.
08Which pays a better dividend — IBIO or ADMA or HALO or TECH?
In this comparison, TECH (0.
7% yield) pays a dividend. IBIO, ADMA, HALO do not pay a meaningful dividend and should not be held primarily for income.
09Is IBIO or ADMA or HALO or TECH better for a retirement portfolio?
For long-horizon retirement investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 51), +559. 7% 10Y return). iBio, Inc. (IBIO) carries a higher beta of 2. 10 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HALO: +559. 7%, IBIO: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between IBIO and ADMA and HALO and TECH?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: IBIO is a small-cap high-growth stock; ADMA is a small-cap high-growth stock; HALO is a small-cap high-growth stock; TECH is a small-cap quality compounder stock. TECH pays a dividend while IBIO, ADMA, HALO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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