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IFRX vs ALXO
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
IFRX vs ALXO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $181M | $112M |
| Revenue (TTM) | $28K | $0.00 |
| Net Income (TTM) | $-44M | $-108M |
| Gross Margin | -261.1% | — |
| Operating Margin | -1735.9% | — |
| Total Debt | $898K | $17M |
| Cash & Equiv. | $16M | $18M |
IFRX vs ALXO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 20 | May 26 | Return |
|---|---|---|---|
| InflaRx N.V. (IFRX) | 100 | 49.8 | -50.2% |
| ALX Oncology Holdin… (ALXO) | 100 | 6.4 | -93.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: IFRX vs ALXO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
IFRX is the clearest fit if your priority is long-term compounding.
- -83.3% 10Y total return vs ALXO's -93.0%
- -62.4% ROA vs ALXO's -130.6%, ROIC -104.4% vs -71.8%
ALXO carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.44
- EPS growth 31.0%
- Lower volatility, beta 1.44, Low D/E 14.9%, current ratio 7.26x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 28.6% revenue growth vs IFRX's -83.0% | |
| Quality / Margins | 5.2% margin vs IFRX's -1.6K% | |
| Stability / Safety | Beta 1.44 vs IFRX's 2.08 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +314.9% vs IFRX's +55.3% | |
| Efficiency (ROA) | -62.4% ROA vs ALXO's -130.6%, ROIC -104.4% vs -71.8% |
IFRX vs ALXO — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
ALXO leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
IFRX and ALXO operate at a comparable scale, with $28,173 and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $28,173 | $0 |
| EBITDAEarnings before interest/tax | -$49M | -$111M |
| Net IncomeAfter-tax profit | -$44M | -$108M |
| Free Cash FlowCash after capex | -$35M | -$97M |
| Gross MarginGross profit ÷ Revenue | -261.1% | — |
| Operating MarginEBIT ÷ Revenue | -1735.9% | — |
| Net MarginNet income ÷ Revenue | -1555.8% | — |
| FCF MarginFCF ÷ Revenue | -1257.6% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | -82.0% | — |
| EPS Growth (YoY)Latest quarter vs prior year | -61.3% | +29.3% |
Valuation Metrics
Evenly matched — IFRX and ALXO each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $181M | $112M |
| Enterprise ValueMkt cap + debt − cash | $163M | $111M |
| Trailing P/EPrice ÷ TTM EPS | -3.23x | -0.81x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | 5466.30x | — |
| Price / BookPrice ÷ Book value/share | 3.45x | 0.96x |
| Price / FCFMarket cap ÷ FCF | — | — |
Profitability & Efficiency
IFRX leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
IFRX delivers a -81.8% return on equity — every $100 of shareholder capital generates $-82 in annual profit, vs $-2 for ALXO. IFRX carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALXO's 0.15x. On the Piotroski fundamental quality scale (0–9), ALXO scores 2/9 vs IFRX's 1/9, reflecting mixed financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -81.8% | -2.4% |
| ROA (TTM)Return on assets | -62.4% | -130.6% |
| ROICReturn on invested capital | -104.4% | -71.8% |
| ROCEReturn on capital employed | -94.0% | -84.8% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 |
| Debt / EquityFinancial leverage | 0.02x | 0.15x |
| Net DebtTotal debt minus cash | -$15M | -$589,000 |
| Cash & Equiv.Liquid assets | $16M | $18M |
| Total DebtShort + long-term debt | $897,532 | $17M |
| Interest CoverageEBIT ÷ Interest expense | -1297.60x | -64.62x |
Total Returns (Dividends Reinvested)
IFRX leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IFRX five years ago would be worth $7,375 today (with dividends reinvested), compared to $333 for ALXO. Over the past 12 months, ALXO leads with a +314.9% total return vs IFRX's +55.3%. The 3-year compound annual growth rate (CAGR) favors IFRX at -15.2% vs ALXO's -30.1% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +129.4% | +81.7% |
| 1-Year ReturnPast 12 months | +55.3% | +314.9% |
| 3-Year ReturnCumulative with dividends | -39.0% | -65.9% |
| 5-Year ReturnCumulative with dividends | -26.3% | -96.7% |
| 10-Year ReturnCumulative with dividends | -83.3% | -93.0% |
| CAGR (3Y)Annualised 3-year return | -15.2% | -30.1% |
Risk & Volatility
Evenly matched — IFRX and ALXO each lead in 1 of 2 comparable metrics.
Risk & Volatility
ALXO is the less volatile stock with a 1.44 beta — it tends to amplify market swings less than IFRX's 2.08 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IFRX currently trades 87.4% from its 52-week high vs ALXO's 78.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.08x | 1.44x |
| 52-Week HighHighest price in past year | $2.86 | $2.66 |
| 52-Week LowLowest price in past year | $0.71 | $0.40 |
| % of 52W HighCurrent price vs 52-week peak | +87.4% | +78.6% |
| RSI (14)Momentum oscillator 0–100 | 70.2 | 57.7 |
| Avg Volume (50D)Average daily shares traded | 1.2M | 930K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates IFRX as "Buy" and ALXO as "Buy". Consensus price targets imply 91.4% upside for ALXO (target: $4) vs -20.0% for IFRX (target: $2).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $2.00 | $4.00 |
| # AnalystsCovering analysts | 15 | 7 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
IFRX leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). ALXO leads in 1 (Income & Cash Flow). 2 tied.
IFRX vs ALXO: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is IFRX or ALXO a better buy right now?
Analysts rate InflaRx N.
V. (IFRX) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — IFRX or ALXO?
Over the past 5 years, InflaRx N.
V. (IFRX) delivered a total return of -26. 3%, compared to -96. 7% for ALX Oncology Holdings Inc. (ALXO). Over 10 years, the gap is even starker: IFRX returned -83. 3% versus ALXO's -93. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — IFRX or ALXO?
By beta (market sensitivity over 5 years), ALX Oncology Holdings Inc.
(ALXO) is the lower-risk stock at 1. 44β versus InflaRx N. V. 's 2. 08β — meaning IFRX is approximately 44% more volatile than ALXO relative to the S&P 500. On balance sheet safety, InflaRx N. V. (IFRX) carries a lower debt/equity ratio of 2% versus 15% for ALX Oncology Holdings Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — IFRX or ALXO?
On earnings-per-share growth, the picture is similar: ALX Oncology Holdings Inc.
grew EPS 31. 0% year-over-year, compared to 15. 4% for InflaRx N. V.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — IFRX or ALXO?
ALX Oncology Holdings Inc.
(ALXO) is the more profitable company, earning 0. 0% net margin versus -1555. 8% for InflaRx N. V. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALXO leads at 0. 0% versus -1735. 9% for IFRX. At the gross margin level — before operating expenses — ALXO leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — IFRX or ALXO?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is IFRX or ALXO better for a retirement portfolio?
For long-horizon retirement investors, ALX Oncology Holdings Inc.
(ALXO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding. InflaRx N. V. (IFRX) carries a higher beta of 2. 08 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ALXO: -93. 0%, IFRX: -83. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between IFRX and ALXO?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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