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Stock Comparison

IMCR vs KYMR vs RCUS vs BEAM vs NTLA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IMCR
Immunocore Holdings plc

Biotechnology

HealthcareNASDAQ • GB
Market Cap$1.55B
5Y Perf.-36.7%
KYMR
Kymera Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.91B
5Y Perf.+76.4%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.-29.7%
BEAM
Beam Therapeutics Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.23B
5Y Perf.-64.7%
NTLA
Intellia Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.62B
5Y Perf.-77.3%

IMCR vs KYMR vs RCUS vs BEAM vs NTLA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IMCR logoIMCR
KYMR logoKYMR
RCUS logoRCUS
BEAM logoBEAM
NTLA logoNTLA
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$1.55B$6.91B$2.50B$3.23B$1.62B
Revenue (TTM)$386M$51M$236M$132M$68M
Net Income (TTM)$-19M$-315M$-369M$-65M$-413M
Gross Margin98.8%33.2%90.7%-64.2%-25.6%
Operating Margin-7.6%-7.0%-168.6%-281.0%-6.5%
Total Debt$44M$82M$99M$294M$93M
Cash & Equiv.$468M$357M$222M$295M$155M

IMCR vs KYMR vs RCUS vs BEAM vs NTLALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IMCR
KYMR
RCUS
BEAM
NTLA
StockFeb 21May 26Return
Immunocore Holdings… (IMCR)10063.3-36.7%
Kymera Therapeutics… (KYMR)100176.4+76.4%
Arcus Biosciences, … (RCUS)10070.3-29.7%
Beam Therapeutics I… (BEAM)10035.3-64.7%
Intellia Therapeuti… (NTLA)10022.7-77.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: IMCR vs KYMR vs RCUS vs BEAM vs NTLA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IMCR leads in 3 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. Arcus Biosciences, Inc. is the stronger pick specifically for recent price momentum and sentiment. BEAM also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
IMCR
Immunocore Holdings plc
The Income Pick

IMCR carries the broadest edge in this set and is the clearest fit for income & stability.

  • beta 0.86
  • -4.9% margin vs KYMR's -6.1%
  • Beta 0.86 vs NTLA's 2.37, lower leverage
  • -1.7% ROA vs NTLA's -45.2%, ROIC -17.2% vs -44.0%
Best for: income & stability
KYMR
Kymera Therapeutics, Inc.
The Long-Run Compounder

KYMR is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 154.4% 10Y total return vs RCUS's 45.9%
  • Lower volatility, beta 1.15, Low D/E 5.2%, current ratio 10.47x
  • Beta 1.15, current ratio 10.47x
Best for: long-term compounding and sleep-well-at-night
RCUS
Arcus Biosciences, Inc.
The Momentum Pick

RCUS is the #2 pick in this set and the best alternative if momentum is your priority.

  • +209.6% vs IMCR's +2.3%
Best for: momentum
BEAM
Beam Therapeutics Inc.
The Growth Play

BEAM ranks third and is worth considering specifically for growth exposure.

  • Rev growth 120.0%, EPS growth 82.3%, 3Y rev CAGR 31.9%
  • 120.0% revenue growth vs KYMR's -16.7%
Best for: growth exposure
NTLA
Intellia Therapeutics, Inc.
The Healthcare Pick

Among these 5 stocks, NTLA doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthBEAM logoBEAM120.0% revenue growth vs KYMR's -16.7%
Quality / MarginsIMCR logoIMCR-4.9% margin vs KYMR's -6.1%
Stability / SafetyIMCR logoIMCRBeta 0.86 vs NTLA's 2.37, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)RCUS logoRCUS+209.6% vs IMCR's +2.3%
Efficiency (ROA)IMCR logoIMCR-1.7% ROA vs NTLA's -45.2%, ROIC -17.2% vs -44.0%

IMCR vs KYMR vs RCUS vs BEAM vs NTLA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IMCRImmunocore Holdings plc
FY 2025
Sale of Therapies
100.0%$400M
KYMRKymera Therapeutics, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
BEAMBeam Therapeutics Inc.

Segment breakdown not available.

NTLAIntellia Therapeutics, Inc.

Segment breakdown not available.

IMCR vs KYMR vs RCUS vs BEAM vs NTLA — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIMCRLAGGINGNTLA

Income & Cash Flow (Last 12 Months)

IMCR leads this category, winning 5 of 6 comparable metrics.

IMCR is the larger business by revenue, generating $386M annually — 7.5x KYMR's $51M. Profitability is closely matched — net margins range from -4.9% (IMCR) to -6.1% (KYMR). On growth, NTLA holds the edge at +78.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIMCR logoIMCRImmunocore Holdin…KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…BEAM logoBEAMBeam Therapeutics…NTLA logoNTLAIntellia Therapeu…
RevenueTrailing 12 months$386M$51M$236M$132M$68M
EBITDAEarnings before interest/tax-$27M-$352M-$391M-$355M-$431M
Net IncomeAfter-tax profit-$19M-$315M-$369M-$65M-$413M
Free Cash FlowCash after capex-$31M-$244M-$489M-$384M-$396M
Gross MarginGross profit ÷ Revenue+98.8%+33.2%+90.7%-64.2%-25.6%
Operating MarginEBIT ÷ Revenue-7.6%-7.0%-168.6%-2.8%-6.5%
Net MarginNet income ÷ Revenue-4.9%-6.1%-156.4%-49.2%-6.1%
FCF MarginFCF ÷ Revenue-8.0%-4.7%-2.1%-2.9%-5.8%
Rev. Growth (YoY)Latest quarter vs prior year+13.6%+55.5%-39.3%-100.0%+78.8%
EPS Growth (YoY)Latest quarter vs prior year+157.5%+13.4%+10.5%+26.6%+34.6%
IMCR leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

IMCR leads this category, winning 2 of 3 comparable metrics.
MetricIMCR logoIMCRImmunocore Holdin…KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…BEAM logoBEAMBeam Therapeutics…NTLA logoNTLAIntellia Therapeu…
Market CapShares × price$1.6B$6.9B$2.5B$3.2B$1.6B
Enterprise ValueMkt cap + debt − cash$1.1B$6.6B$2.4B$3.2B$1.6B
Trailing P/EPrice ÷ TTM EPS-57.77x-22.93x-7.54x-38.85x-3.60x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue5.22x176.26x10.11x23.14x23.93x
Price / BookPrice ÷ Book value/share4.05x4.52x4.22x2.51x2.21x
Price / FCFMarket cap ÷ FCF
IMCR leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

IMCR leads this category, winning 7 of 9 comparable metrics.

IMCR delivers a -4.8% return on equity — every $100 of shareholder capital generates $-5 in annual profit, vs $-69 for RCUS. KYMR carries lower financial leverage with a 0.05x debt-to-equity ratio, signaling a more conservative balance sheet compared to BEAM's 0.24x. On the Piotroski fundamental quality scale (0–9), IMCR scores 5/9 vs RCUS's 0/9, reflecting solid financial health.

MetricIMCR logoIMCRImmunocore Holdin…KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…BEAM logoBEAMBeam Therapeutics…NTLA logoNTLAIntellia Therapeu…
ROE (TTM)Return on equity-4.8%-25.0%-69.0%-5.9%-56.6%
ROA (TTM)Return on assets-1.7%-22.3%-35.3%-4.6%-45.2%
ROICReturn on invested capital-17.2%-24.9%-64.1%-31.1%-44.0%
ROCEReturn on capital employed-4.2%-27.2%-42.1%-33.3%-48.5%
Piotroski ScoreFundamental quality 0–954044
Debt / EquityFinancial leverage0.11x0.05x0.16x0.24x0.14x
Net DebtTotal debt minus cash-$424M-$275M-$123M-$1M-$62M
Cash & Equiv.Liquid assets$468M$357M$222M$295M$155M
Total DebtShort + long-term debt$44M$82M$99M$294M$93M
Interest CoverageEBIT ÷ Interest expense-2.04x-2119.53x-13.38x1.08x
IMCR leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

KYMR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $2,024 for NTLA. Over the past 12 months, RCUS leads with a +209.6% total return vs IMCR's +2.3%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs NTLA's -31.8% — a key indicator of consistent wealth creation.

MetricIMCR logoIMCRImmunocore Holdin…KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…BEAM logoBEAMBeam Therapeutics…NTLA logoNTLAIntellia Therapeu…
YTD ReturnYear-to-date-9.4%+16.3%+6.5%+16.0%+48.9%
1-Year ReturnPast 12 months+2.3%+190.7%+209.6%+93.9%+88.1%
3-Year ReturnCumulative with dividends-48.9%+205.1%+24.9%-5.6%-68.3%
5-Year ReturnCumulative with dividends-24.0%+92.1%-18.6%-55.6%-79.8%
10-Year ReturnCumulative with dividends-29.1%+154.4%+45.9%+67.8%-42.9%
CAGR (3Y)Annualised 3-year return-20.0%+45.0%+7.7%-1.9%-31.8%
KYMR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IMCR and BEAM each lead in 1 of 2 comparable metrics.

IMCR is the less volatile stock with a 0.86 beta — it tends to amplify market swings less than NTLA's 2.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BEAM currently trades 86.4% from its 52-week high vs NTLA's 48.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIMCR logoIMCRImmunocore Holdin…KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…BEAM logoBEAMBeam Therapeutics…NTLA logoNTLAIntellia Therapeu…
Beta (5Y)Sensitivity to S&P 5000.86x1.15x1.95x2.14x2.37x
52-Week HighHighest price in past year$40.72$103.00$28.72$36.44$28.25
52-Week LowLowest price in past year$27.44$28.06$7.06$15.35$6.83
% of 52W HighCurrent price vs 52-week peak+75.2%+82.2%+86.3%+86.4%+48.5%
RSI (14)Momentum oscillator 0–10055.854.160.560.950.4
Avg Volume (50D)Average daily shares traded409K602K1.2M2.0M5.3M
Evenly matched — IMCR and BEAM each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: IMCR as "Buy", KYMR as "Buy", RCUS as "Buy", BEAM as "Buy", NTLA as "Buy". Consensus price targets imply 52.3% upside for NTLA (target: $21) vs 21.0% for RCUS (target: $30).

MetricIMCR logoIMCRImmunocore Holdin…KYMR logoKYMRKymera Therapeuti…RCUS logoRCUSArcus Biosciences…BEAM logoBEAMBeam Therapeutics…NTLA logoNTLAIntellia Therapeu…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$43.00$117.06$30.00$40.83$20.88
# AnalystsCovering analysts1426182739
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

IMCR leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). KYMR leads in 1 (Total Returns). 1 tied.

Best OverallImmunocore Holdings plc (IMCR)Leads 3 of 6 categories
Loading custom metrics...

IMCR vs KYMR vs RCUS vs BEAM vs NTLA: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is IMCR or KYMR or RCUS or BEAM or NTLA a better buy right now?

For growth investors, Beam Therapeutics Inc.

(BEAM) is the stronger pick with 120. 0% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Analysts rate Immunocore Holdings plc (IMCR) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — IMCR or KYMR or RCUS or BEAM or NTLA?

Over the past 5 years, Kymera Therapeutics, Inc.

(KYMR) delivered a total return of +92. 1%, compared to -79. 8% for Intellia Therapeutics, Inc. (NTLA). Over 10 years, the gap is even starker: KYMR returned +154. 4% versus NTLA's -42. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — IMCR or KYMR or RCUS or BEAM or NTLA?

By beta (market sensitivity over 5 years), Immunocore Holdings plc (IMCR) is the lower-risk stock at 0.

86β versus Intellia Therapeutics, Inc. 's 2. 37β — meaning NTLA is approximately 175% more volatile than IMCR relative to the S&P 500. On balance sheet safety, Kymera Therapeutics, Inc. (KYMR) carries a lower debt/equity ratio of 5% versus 24% for Beam Therapeutics Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — IMCR or KYMR or RCUS or BEAM or NTLA?

By revenue growth (latest reported year), Beam Therapeutics Inc.

(BEAM) is pulling ahead at 120. 0% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Over a 3-year CAGR, BEAM leads at 31. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — IMCR or KYMR or RCUS or BEAM or NTLA?

Immunocore Holdings plc (IMCR) is the more profitable company, earning -8.

9% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps -8. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMCR leads at -11. 3% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — IMCR or KYMR or RCUS or BEAM or NTLA?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is IMCR or KYMR or RCUS or BEAM or NTLA better for a retirement portfolio?

For long-horizon retirement investors, Immunocore Holdings plc (IMCR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

86)). Intellia Therapeutics, Inc. (NTLA) carries a higher beta of 2. 37 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMCR: -29. 1%, NTLA: -42. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between IMCR and KYMR and RCUS and BEAM and NTLA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IMCR is a small-cap high-growth stock; KYMR is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock; NTLA is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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IMCR

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  • Market Cap > $100B
  • Revenue Growth > 6%
  • Gross Margin > 59%
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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 27%
  • Gross Margin > 19%
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RCUS

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 54%
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  • Market Cap > $100B
  • Revenue Growth > 39%
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Beat Both

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Revenue Growth>
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(IMCR: 13.6% · KYMR: 55.5%)

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