INSP vs MDT

For growth investors, Inspire Medical Systems, Inc.

(INSP) is the stronger pick with 13. 6% revenue growth year-over-year, versus 3. 6% for Medtronic plc (MDT). Inspire Medical Systems, Inc. (INSP) offers the better valuation at 9. 3x trailing P/E (24. 5x forward), making it the more compelling value choice. Analysts rate Medtronic plc (MDT) a "Buy" — based on 49 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

On trailing P/E, Inspire Medical Systems, Inc.

(INSP) is the cheapest at 9. 3x versus Medtronic plc at 21. 5x. On forward P/E, Medtronic plc is actually cheaper at 14. 1x — notably different from the trailing picture, reflecting expected earnings growth.

Over the past 5 years, Medtronic plc (MDT) delivered a total return of -28.

3%, compared to -76. 1% for Inspire Medical Systems, Inc. (INSP). Over 10 years, the gap is even starker: INSP returned +82. 9% versus MDT's +27. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

By beta (market sensitivity over 5 years), Medtronic plc (MDT) is the lower-risk stock at 0.

47β versus Inspire Medical Systems, Inc. 's 1. 27β — meaning INSP is approximately 172% more volatile than MDT relative to the S&P 500. On balance sheet safety, Inspire Medical Systems, Inc. (INSP) carries a lower debt/equity ratio of 4% versus 59% for Medtronic plc — giving it more financial flexibility in a downturn.

By revenue growth (latest reported year), Inspire Medical Systems, Inc.

(INSP) is pulling ahead at 13. 6% versus 3. 6% for Medtronic plc (MDT). On earnings-per-share growth, the picture is similar: Inspire Medical Systems, Inc. grew EPS 179. 4% year-over-year, compared to 30. 8% for Medtronic plc. Over a 3-year CAGR, INSP leads at 30. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

Inspire Medical Systems, Inc.

(INSP) is the more profitable company, earning 15. 9% net margin versus 13. 9% for Medtronic plc — meaning it keeps 15. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MDT leads at 17. 8% versus 5. 6% for INSP. At the gross margin level — before operating expenses — INSP leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

On forward earnings alone, Medtronic plc (MDT) trades at 14.

1x forward P/E versus 24. 5x for Inspire Medical Systems, Inc. — 10. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for INSP: 99. 8% to $91. 33.

In this comparison, MDT (3.

6% yield) pays a dividend. INSP does not pay a meaningful dividend and should not be held primarily for income.

For long-horizon retirement investors, Medtronic plc (MDT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

47), 3. 6% yield). Both have compounded well over 10 years (MDT: +27. 0%, INSP: +82. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: INSP is a small-cap deep-value stock; MDT is a mid-cap income-oriented stock. MDT pays a dividend while INSP does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.