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4 / 10Stock Comparison
KALA vs LNTH vs RMD vs OCUL
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Medical - Instruments & Supplies
Biotechnology
KALA vs LNTH vs RMD vs OCUL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - Specialty & Generic | Medical - Instruments & Supplies | Biotechnology |
| Market Cap | $618K | $5.92B | $30.15B | $2.12B |
| Revenue (TTM) | $254K | $1.55B | $5.54B | $52M |
| Net Income (TTM) | $-36M | $279M | $1.52B | $-290M |
| Gross Margin | -3.1% | 60.5% | 61.7% | 87.2% |
| Operating Margin | -150.6% | 18.8% | 34.3% | -5.8% |
| Forward P/E | — | 17.5x | 18.8x | — |
| Total Debt | $32M | $738K | $852M | $80M |
| Cash & Equiv. | $51M | $359M | $1.21B | $737M |
KALA vs LNTH vs RMD vs OCUL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| KALA BIO, Inc. (KALA) | 100 | 0.0 | -100.0% |
| Lantheus Holdings, … (LNTH) | 100 | 662.8 | +562.8% |
| ResMed Inc. (RMD) | 100 | 128.7 | +28.7% |
| Ocular Therapeutix,… (OCUL) | 100 | 137.5 | +37.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KALA vs LNTH vs RMD vs OCUL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
KALA is the clearest fit if your priority is growth exposure.
- Rev growth 262.9%, EPS growth 59.8%
- 262.9% revenue growth vs OCUL's -18.7%
LNTH is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.
- 41.9% 10Y total return vs RMD's 293.8%
- Lower volatility, beta 0.47, Low D/E 0.1%, current ratio 2.70x
- Better valuation composite
- Beta 0.47 vs KALA's 2.09, lower leverage
RMD carries the broadest edge in this set and is the clearest fit for income & stability and defensive.
- Dividend streak 14 yrs, beta 0.66, yield 1.0%
- Beta 0.66, yield 1.0%, current ratio 3.44x
- 27.4% margin vs KALA's -141.1%
- 1.0% yield; 14-year raise streak; the other 3 pay no meaningful dividend
OCUL is the clearest fit if your priority is momentum.
- +37.3% vs KALA's -97.6%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 262.9% revenue growth vs OCUL's -18.7% | |
| Value | Better valuation composite | |
| Quality / Margins | 27.4% margin vs KALA's -141.1% | |
| Stability / Safety | Beta 0.47 vs KALA's 2.09, lower leverage | |
| Dividends | 1.0% yield; 14-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +37.3% vs KALA's -97.6% | |
| Efficiency (ROA) | 18.0% ROA vs KALA's -143.2% |
KALA vs LNTH vs RMD vs OCUL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
KALA vs LNTH vs RMD vs OCUL — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
RMD leads in 3 of 6 categories
LNTH leads 2 • KALA leads 0 • OCUL leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
RMD leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RMD is the larger business by revenue, generating $5.5B annually — 21802.3x KALA's $254,000. RMD is the more profitable business, keeping 27.4% of every revenue dollar as net income compared to KALA's -141.1%. On growth, RMD holds the edge at +10.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $254,000 | $1.5B | $5.5B | $52M |
| EBITDAEarnings before interest/tax | -$38M | $347M | $2.1B | -$295M |
| Net IncomeAfter-tax profit | -$36M | $279M | $1.5B | -$290M |
| Free Cash FlowCash after capex | -$32M | $372M | $1.8B | -$241M |
| Gross MarginGross profit ÷ Revenue | -3.1% | +60.5% | +61.7% | +87.2% |
| Operating MarginEBIT ÷ Revenue | -150.6% | +18.8% | +34.3% | -5.8% |
| Net MarginNet income ÷ Revenue | -141.1% | +18.0% | +27.4% | -5.6% |
| FCF MarginFCF ÷ Revenue | -126.3% | +24.0% | +31.7% | -4.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +1.2% | +10.8% | +0.8% |
| EPS Growth (YoY)Latest quarter vs prior year | +44.6% | +76.5% | +9.3% | -5.3% |
Valuation Metrics
LNTH leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 21.8x trailing earnings, RMD trades at a 18% valuation discount to LNTH's 26.7x P/E. On an enterprise value basis, LNTH's 14.6x EV/EBITDA is more attractive than RMD's 15.5x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $617,676 | $5.9B | $30.1B | $2.1B |
| Enterprise ValueMkt cap + debt − cash | -$18M | $5.6B | $29.8B | $1.5B |
| Trailing P/EPrice ÷ TTM EPS | -0.01x | 26.69x | 21.76x | -6.82x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 17.52x | 18.78x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.25x | — |
| EV / EBITDAEnterprise value multiple | — | 14.61x | 15.51x | — |
| Price / SalesMarket cap ÷ Revenue | — | 3.84x | 5.86x | 40.90x |
| Price / BookPrice ÷ Book value/share | 0.04x | 5.72x | 5.11x | 2.77x |
| Price / FCFMarket cap ÷ FCF | — | 16.73x | 18.14x | — |
Profitability & Efficiency
RMD leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
RMD delivers a 24.4% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-4 for KALA. LNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KALA's 2.62x. On the Piotroski fundamental quality scale (0–9), RMD scores 8/9 vs KALA's 2/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.9% | +24.3% | +24.4% | -64.6% |
| ROA (TTM)Return on assets | -143.2% | +12.4% | +18.0% | -48.4% |
| ROICReturn on invested capital | — | +30.6% | +22.8% | — |
| ROCEReturn on capital employed | -95.2% | +17.1% | +25.7% | -46.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 5 | 8 | 4 |
| Debt / EquityFinancial leverage | 2.62x | 0.00x | 0.14x | 0.12x |
| Net DebtTotal debt minus cash | -$19M | -$358M | -$358M | -$657M |
| Cash & Equiv.Liquid assets | $51M | $359M | $1.2B | $737M |
| Total DebtShort + long-term debt | $32M | $738,000 | $852M | $80M |
| Interest CoverageEBIT ÷ Interest expense | -6.92x | 11.72x | 66.06x | -24.63x |
Total Returns (Dividends Reinvested)
Evenly matched — LNTH and OCUL each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LNTH five years ago would be worth $41,420 today (with dividends reinvested), compared to $3 for KALA. Over the past 12 months, OCUL leads with a +37.3% total return vs KALA's -97.6%. The 3-year compound annual growth rate (CAGR) favors OCUL at 14.8% vs KALA's -82.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -86.6% | +35.3% | -15.2% | -18.1% |
| 1-Year ReturnPast 12 months | -97.6% | +13.1% | -14.5% | +37.3% |
| 3-Year ReturnCumulative with dividends | -99.5% | -4.0% | -8.4% | +51.2% |
| 5-Year ReturnCumulative with dividends | -100.0% | +314.2% | +11.0% | -40.4% |
| 10-Year ReturnCumulative with dividends | -100.0% | +4192.5% | +293.8% | -10.6% |
| CAGR (3Y)Annualised 3-year return | -82.6% | -1.4% | -2.9% | +14.8% |
Risk & Volatility
LNTH leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
LNTH is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than KALA's 2.09 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. LNTH currently trades 97.8% from its 52-week high vs KALA's 0.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.09x | 0.47x | 0.66x | 1.27x |
| 52-Week HighHighest price in past year | $20.60 | $93.00 | $293.81 | $16.44 |
| 52-Week LowLowest price in past year | $0.08 | $47.25 | $198.64 | $6.23 |
| % of 52W HighCurrent price vs 52-week peak | +0.4% | +97.8% | +70.4% | +58.9% |
| RSI (14)Momentum oscillator 0–100 | 30.1 | 61.2 | 35.6 | 58.3 |
| Avg Volume (50D)Average daily shares traded | 9.2M | 886K | 1.1M | 4.0M |
Analyst Outlook
RMD leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: KALA as "Buy", LNTH as "Buy", RMD as "Buy", OCUL as "Buy". Consensus price targets imply 21861.5% upside for KALA (target: $18) vs 11.0% for LNTH (target: $101). RMD is the only dividend payer here at 1.02% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $18.25 | $101.00 | $281.29 | $25.50 |
| # AnalystsCovering analysts | 9 | 17 | 35 | 18 |
| Dividend YieldAnnual dividend ÷ price | — | — | +1.0% | — |
| Dividend StreakConsecutive years of raises | — | 0 | 14 | — |
| Dividend / ShareAnnual DPS | — | — | $2.11 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.1% | +1.0% | 0.0% |
RMD leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). LNTH leads in 2 (Valuation Metrics, Risk & Volatility). 1 tied.
KALA vs LNTH vs RMD vs OCUL: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is KALA or LNTH or RMD or OCUL a better buy right now?
For growth investors, ResMed Inc.
(RMD) is the stronger pick with 9. 8% revenue growth year-over-year, versus -18. 7% for Ocular Therapeutix, Inc. (OCUL). ResMed Inc. (RMD) offers the better valuation at 21. 8x trailing P/E (18. 8x forward), making it the more compelling value choice. Analysts rate KALA BIO, Inc. (KALA) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — KALA or LNTH or RMD or OCUL?
On trailing P/E, ResMed Inc.
(RMD) is the cheapest at 21. 8x versus Lantheus Holdings, Inc. at 26. 7x. On forward P/E, Lantheus Holdings, Inc. is actually cheaper at 17. 5x — notably different from the trailing picture, reflecting expected earnings growth.
03Which is the better long-term investment — KALA or LNTH or RMD or OCUL?
Over the past 5 years, Lantheus Holdings, Inc.
(LNTH) delivered a total return of +314. 2%, compared to -100. 0% for KALA BIO, Inc. (KALA). Over 10 years, the gap is even starker: LNTH returned +41. 9% versus KALA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — KALA or LNTH or RMD or OCUL?
By beta (market sensitivity over 5 years), Lantheus Holdings, Inc.
(LNTH) is the lower-risk stock at 0. 47β versus KALA BIO, Inc. 's 2. 09β — meaning KALA is approximately 346% more volatile than LNTH relative to the S&P 500. On balance sheet safety, Lantheus Holdings, Inc. (LNTH) carries a lower debt/equity ratio of 0% versus 3% for KALA BIO, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — KALA or LNTH or RMD or OCUL?
By revenue growth (latest reported year), ResMed Inc.
(RMD) is pulling ahead at 9. 8% versus -18. 7% for Ocular Therapeutix, Inc. (OCUL). On earnings-per-share growth, the picture is similar: KALA BIO, Inc. grew EPS 59. 8% year-over-year, compared to -21. 8% for Lantheus Holdings, Inc.. Over a 3-year CAGR, LNTH leads at 18. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — KALA or LNTH or RMD or OCUL?
ResMed Inc.
(RMD) is the more profitable company, earning 27. 2% net margin versus -141. 1% for KALA BIO, Inc. — meaning it keeps 27. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RMD leads at 32. 7% versus -150. 6% for KALA. At the gross margin level — before operating expenses — OCUL leads at 87. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is KALA or LNTH or RMD or OCUL more undervalued right now?
On forward earnings alone, Lantheus Holdings, Inc.
(LNTH) trades at 17. 5x forward P/E versus 18. 8x for ResMed Inc. — 1. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KALA: 21861. 5% to $18. 25.
08Which pays a better dividend — KALA or LNTH or RMD or OCUL?
In this comparison, RMD (1.
0% yield) pays a dividend. KALA, LNTH, OCUL do not pay a meaningful dividend and should not be held primarily for income.
09Is KALA or LNTH or RMD or OCUL better for a retirement portfolio?
For long-horizon retirement investors, ResMed Inc.
(RMD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), 1. 0% yield, +293. 8% 10Y return). KALA BIO, Inc. (KALA) carries a higher beta of 2. 09 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RMD: +293. 8%, KALA: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between KALA and LNTH and RMD and OCUL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
RMD pays a dividend while KALA, LNTH, OCUL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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