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Stock Comparison

KALA vs LNTH vs RMD vs OCUL vs NVCR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
KALA
KALA BIO, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$618K
5Y Perf.-100.0%
LNTH
Lantheus Holdings, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$5.92B
5Y Perf.+562.8%
RMD
ResMed Inc.

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$30.15B
5Y Perf.+28.7%
OCUL
Ocular Therapeutix, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2.12B
5Y Perf.+37.5%
NVCR
NovoCure Limited

Medical - Instruments & Supplies

HealthcareNASDAQ • JE
Market Cap$1.92B
5Y Perf.-75.0%

KALA vs LNTH vs RMD vs OCUL vs NVCR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
KALA logoKALA
LNTH logoLNTH
RMD logoRMD
OCUL logoOCUL
NVCR logoNVCR
IndustryBiotechnologyDrug Manufacturers - Specialty & GenericMedical - Instruments & SuppliesBiotechnologyMedical - Instruments & Supplies
Market Cap$618K$5.92B$30.15B$2.12B$1.92B
Revenue (TTM)$254K$1.55B$5.54B$52M$674M
Net Income (TTM)$-36M$279M$1.52B$-290M$-173M
Gross Margin-3.1%60.5%61.7%87.2%75.2%
Operating Margin-150.6%18.8%34.3%-5.8%-27.2%
Forward P/E17.5x18.8x
Total Debt$32M$738K$852M$80M$290M
Cash & Equiv.$51M$359M$1.21B$737M$103M

KALA vs LNTH vs RMD vs OCUL vs NVCRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

KALA
LNTH
RMD
OCUL
NVCR
StockMay 20May 26Return
KALA BIO, Inc. (KALA)1000.0-100.0%
Lantheus Holdings, … (LNTH)100662.8+562.8%
ResMed Inc. (RMD)100128.7+28.7%
Ocular Therapeutix,… (OCUL)100137.5+37.5%
NovoCure Limited (NVCR)10025.0-75.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: KALA vs LNTH vs RMD vs OCUL vs NVCR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: RMD leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Lantheus Holdings, Inc. is the stronger pick specifically for valuation and capital efficiency and capital preservation and lower volatility. KALA and OCUL also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
KALA
KALA BIO, Inc.
The Growth Play

KALA ranks third and is worth considering specifically for growth exposure.

  • Rev growth 262.9%, EPS growth 59.8%
  • 262.9% revenue growth vs OCUL's -18.7%
Best for: growth exposure
LNTH
Lantheus Holdings, Inc.
The Long-Run Compounder

LNTH is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.

  • 41.9% 10Y total return vs RMD's 293.8%
  • Lower volatility, beta 0.47, Low D/E 0.1%, current ratio 2.70x
  • Better valuation composite
  • Beta 0.47 vs NVCR's 2.20, lower leverage
Best for: long-term compounding and sleep-well-at-night
RMD
ResMed Inc.
The Income Pick

RMD carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • Dividend streak 14 yrs, beta 0.66, yield 1.0%
  • Beta 0.66, yield 1.0%, current ratio 3.44x
  • 27.4% margin vs KALA's -141.1%
  • 1.0% yield; 14-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability and defensive
OCUL
Ocular Therapeutix, Inc.
The Momentum Pick

OCUL is the clearest fit if your priority is momentum.

  • +37.3% vs KALA's -97.6%
Best for: momentum
NVCR
NovoCure Limited
The Healthcare Pick

Among these 5 stocks, NVCR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthKALA logoKALA262.9% revenue growth vs OCUL's -18.7%
ValueLNTH logoLNTHBetter valuation composite
Quality / MarginsRMD logoRMD27.4% margin vs KALA's -141.1%
Stability / SafetyLNTH logoLNTHBeta 0.47 vs NVCR's 2.20, lower leverage
DividendsRMD logoRMD1.0% yield; 14-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)OCUL logoOCUL+37.3% vs KALA's -97.6%
Efficiency (ROA)RMD logoRMD18.0% ROA vs KALA's -143.2%

KALA vs LNTH vs RMD vs OCUL vs NVCR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

KALAKALA BIO, Inc.

Segment breakdown not available.

LNTHLantheus Holdings, Inc.
FY 2025
Product
33.4%$1.5B
Radiopharmaceutical Oncology
21.9%$989M
PYLARIFY
21.9%$989M
Total Precision Diagnostics
10.9%$493M
DEFINITY
7.3%$330M
Techne Lite
1.9%$87M
Strategic Partnerships And Other
1.3%$59M
Other (2)
1.3%$59M
RMDResMed Inc.
FY 2024
Sleep And Respiratory
87.5%$4.1B
Software As Service
12.5%$584M
OCULOcular Therapeutix, Inc.
FY 2025
Product
99.8%$52M
Collaboration revenue
0.2%$128,000
NVCRNovoCure Limited

Segment breakdown not available.

KALA vs LNTH vs RMD vs OCUL vs NVCR — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLRMDLAGGINGNVCR

Income & Cash Flow (Last 12 Months)

RMD leads this category, winning 3 of 6 comparable metrics.

RMD is the larger business by revenue, generating $5.5B annually — 21802.3x KALA's $254,000. RMD is the more profitable business, keeping 27.4% of every revenue dollar as net income compared to KALA's -141.1%. On growth, NVCR holds the edge at +12.3% YoY revenue growth, suggesting stronger near-term business momentum.

MetricKALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RMD logoRMDResMed Inc.OCUL logoOCULOcular Therapeuti…NVCR logoNVCRNovoCure Limited
RevenueTrailing 12 months$254,000$1.5B$5.5B$52M$674M
EBITDAEarnings before interest/tax-$38M$347M$2.1B-$295M-$165M
Net IncomeAfter-tax profit-$36M$279M$1.5B-$290M-$173M
Free Cash FlowCash after capex-$32M$372M$1.8B-$241M-$48M
Gross MarginGross profit ÷ Revenue-3.1%+60.5%+61.7%+87.2%+75.2%
Operating MarginEBIT ÷ Revenue-150.6%+18.8%+34.3%-5.8%-27.2%
Net MarginNet income ÷ Revenue-141.1%+18.0%+27.4%-5.6%-25.7%
FCF MarginFCF ÷ Revenue-126.3%+24.0%+31.7%-4.6%-7.1%
Rev. Growth (YoY)Latest quarter vs prior year+1.2%+10.8%+0.8%+12.3%
EPS Growth (YoY)Latest quarter vs prior year+44.6%+76.5%+9.3%-5.3%-100.0%
RMD leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

LNTH leads this category, winning 3 of 6 comparable metrics.

At 21.8x trailing earnings, RMD trades at a 18% valuation discount to LNTH's 26.7x P/E. On an enterprise value basis, LNTH's 14.6x EV/EBITDA is more attractive than RMD's 15.5x.

MetricKALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RMD logoRMDResMed Inc.OCUL logoOCULOcular Therapeuti…NVCR logoNVCRNovoCure Limited
Market CapShares × price$617,676$5.9B$30.1B$2.1B$1.9B
Enterprise ValueMkt cap + debt − cash-$18M$5.6B$29.8B$1.5B$2.1B
Trailing P/EPrice ÷ TTM EPS-0.01x26.69x21.76x-6.82x-13.80x
Forward P/EPrice ÷ next-FY EPS est.17.52x18.78x
PEG RatioP/E ÷ EPS growth rate1.25x
EV / EBITDAEnterprise value multiple14.61x15.51x
Price / SalesMarket cap ÷ Revenue3.84x5.86x40.90x2.92x
Price / BookPrice ÷ Book value/share0.04x5.72x5.11x2.77x5.51x
Price / FCFMarket cap ÷ FCF16.73x18.14x
LNTH leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

RMD leads this category, winning 5 of 9 comparable metrics.

RMD delivers a 24.4% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-4 for KALA. LNTH carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to KALA's 2.62x. On the Piotroski fundamental quality scale (0–9), RMD scores 8/9 vs KALA's 2/9, reflecting strong financial health.

MetricKALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RMD logoRMDResMed Inc.OCUL logoOCULOcular Therapeuti…NVCR logoNVCRNovoCure Limited
ROE (TTM)Return on equity-3.9%+24.3%+24.4%-64.6%-50.8%
ROA (TTM)Return on assets-143.2%+12.4%+18.0%-48.4%-16.5%
ROICReturn on invested capital+30.6%+22.8%-16.4%
ROCEReturn on capital employed-95.2%+17.1%+25.7%-46.0%-28.9%
Piotroski ScoreFundamental quality 0–925845
Debt / EquityFinancial leverage2.62x0.00x0.14x0.12x0.85x
Net DebtTotal debt minus cash-$19M-$358M-$358M-$657M$187M
Cash & Equiv.Liquid assets$51M$359M$1.2B$737M$103M
Total DebtShort + long-term debt$32M$738,000$852M$80M$290M
Interest CoverageEBIT ÷ Interest expense-6.92x11.72x66.06x-24.63x-96.80x
RMD leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — LNTH and OCUL each lead in 3 of 6 comparable metrics.

A $10,000 investment in LNTH five years ago would be worth $41,420 today (with dividends reinvested), compared to $3 for KALA. Over the past 12 months, OCUL leads with a +37.3% total return vs KALA's -97.6%. The 3-year compound annual growth rate (CAGR) favors OCUL at 14.8% vs KALA's -82.6% — a key indicator of consistent wealth creation.

MetricKALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RMD logoRMDResMed Inc.OCUL logoOCULOcular Therapeuti…NVCR logoNVCRNovoCure Limited
YTD ReturnYear-to-date-86.6%+35.3%-15.2%-18.1%+28.3%
1-Year ReturnPast 12 months-97.6%+13.1%-14.5%+37.3%+1.1%
3-Year ReturnCumulative with dividends-99.5%-4.0%-8.4%+51.2%-75.7%
5-Year ReturnCumulative with dividends-100.0%+314.2%+11.0%-40.4%-91.3%
10-Year ReturnCumulative with dividends-100.0%+4192.5%+293.8%-10.6%+30.3%
CAGR (3Y)Annualised 3-year return-82.6%-1.4%-2.9%+14.8%-37.6%
Evenly matched — LNTH and OCUL each lead in 3 of 6 comparable metrics.

Risk & Volatility

LNTH leads this category, winning 2 of 2 comparable metrics.

LNTH is the less volatile stock with a 0.47 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. LNTH currently trades 97.8% from its 52-week high vs KALA's 0.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricKALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RMD logoRMDResMed Inc.OCUL logoOCULOcular Therapeuti…NVCR logoNVCRNovoCure Limited
Beta (5Y)Sensitivity to S&P 5002.09x0.47x0.66x1.27x2.20x
52-Week HighHighest price in past year$20.60$93.00$293.81$16.44$20.06
52-Week LowLowest price in past year$0.08$47.25$198.64$6.23$9.82
% of 52W HighCurrent price vs 52-week peak+0.4%+97.8%+70.4%+58.9%+83.9%
RSI (14)Momentum oscillator 0–10030.161.235.658.369.8
Avg Volume (50D)Average daily shares traded9.2M886K1.1M4.0M1.5M
LNTH leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

RMD leads this category, winning 1 of 1 comparable metric.

Analyst consensus: KALA as "Buy", LNTH as "Buy", RMD as "Buy", OCUL as "Buy", NVCR as "Buy". Consensus price targets imply 21861.5% upside for KALA (target: $18) vs 11.0% for LNTH (target: $101). RMD is the only dividend payer here at 1.02% yield — a key consideration for income-focused portfolios.

MetricKALA logoKALAKALA BIO, Inc.LNTH logoLNTHLantheus Holdings…RMD logoRMDResMed Inc.OCUL logoOCULOcular Therapeuti…NVCR logoNVCRNovoCure Limited
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$18.25$101.00$281.29$25.50$33.50
# AnalystsCovering analysts917351815
Dividend YieldAnnual dividend ÷ price+1.0%
Dividend StreakConsecutive years of raises014
Dividend / ShareAnnual DPS$2.11
Buyback YieldShare repurchases ÷ mkt cap0.0%+5.1%+1.0%0.0%0.0%
RMD leads this category, winning 1 of 1 comparable metric.
Key Takeaway

RMD leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). LNTH leads in 2 (Valuation Metrics, Risk & Volatility). 1 tied.

Best OverallResMed Inc. (RMD)Leads 3 of 6 categories
Loading custom metrics...

KALA vs LNTH vs RMD vs OCUL vs NVCR: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is KALA or LNTH or RMD or OCUL or NVCR a better buy right now?

For growth investors, ResMed Inc.

(RMD) is the stronger pick with 9. 8% revenue growth year-over-year, versus -18. 7% for Ocular Therapeutix, Inc. (OCUL). ResMed Inc. (RMD) offers the better valuation at 21. 8x trailing P/E (18. 8x forward), making it the more compelling value choice. Analysts rate KALA BIO, Inc. (KALA) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — KALA or LNTH or RMD or OCUL or NVCR?

On trailing P/E, ResMed Inc.

(RMD) is the cheapest at 21. 8x versus Lantheus Holdings, Inc. at 26. 7x. On forward P/E, Lantheus Holdings, Inc. is actually cheaper at 17. 5x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — KALA or LNTH or RMD or OCUL or NVCR?

Over the past 5 years, Lantheus Holdings, Inc.

(LNTH) delivered a total return of +314. 2%, compared to -100. 0% for KALA BIO, Inc. (KALA). Over 10 years, the gap is even starker: LNTH returned +41. 9% versus KALA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — KALA or LNTH or RMD or OCUL or NVCR?

By beta (market sensitivity over 5 years), Lantheus Holdings, Inc.

(LNTH) is the lower-risk stock at 0. 47β versus NovoCure Limited's 2. 20β — meaning NVCR is approximately 370% more volatile than LNTH relative to the S&P 500. On balance sheet safety, Lantheus Holdings, Inc. (LNTH) carries a lower debt/equity ratio of 0% versus 3% for KALA BIO, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — KALA or LNTH or RMD or OCUL or NVCR?

By revenue growth (latest reported year), ResMed Inc.

(RMD) is pulling ahead at 9. 8% versus -18. 7% for Ocular Therapeutix, Inc. (OCUL). On earnings-per-share growth, the picture is similar: KALA BIO, Inc. grew EPS 59. 8% year-over-year, compared to -21. 8% for Lantheus Holdings, Inc.. Over a 3-year CAGR, LNTH leads at 18. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — KALA or LNTH or RMD or OCUL or NVCR?

ResMed Inc.

(RMD) is the more profitable company, earning 27. 2% net margin versus -141. 1% for KALA BIO, Inc. — meaning it keeps 27. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RMD leads at 32. 7% versus -150. 6% for KALA. At the gross margin level — before operating expenses — OCUL leads at 87. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is KALA or LNTH or RMD or OCUL or NVCR more undervalued right now?

On forward earnings alone, Lantheus Holdings, Inc.

(LNTH) trades at 17. 5x forward P/E versus 18. 8x for ResMed Inc. — 1. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KALA: 21861. 5% to $18. 25.

08

Which pays a better dividend — KALA or LNTH or RMD or OCUL or NVCR?

In this comparison, RMD (1.

0% yield) pays a dividend. KALA, LNTH, OCUL, NVCR do not pay a meaningful dividend and should not be held primarily for income.

09

Is KALA or LNTH or RMD or OCUL or NVCR better for a retirement portfolio?

For long-horizon retirement investors, ResMed Inc.

(RMD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), 1. 0% yield, +293. 8% 10Y return). KALA BIO, Inc. (KALA) carries a higher beta of 2. 09 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RMD: +293. 8%, KALA: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between KALA and LNTH and RMD and OCUL and NVCR?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

RMD pays a dividend while KALA, LNTH, OCUL, NVCR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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