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KMDA vs GRFS vs CSL vs BIO vs BRKR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
KMDA
Kamada Ltd.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • IL
Market Cap$476M
5Y Perf.+5.2%
GRFS
Grifols, S.A.

Drug Manufacturers - General

HealthcareNASDAQ • ES
Market Cap$6.82B
5Y Perf.-57.4%
CSL
Carlisle Companies Incorporated

Construction

IndustrialsNYSE • US
Market Cap$14.73B
5Y Perf.+200.7%
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.95B
5Y Perf.-47.6%
BRKR
Bruker Corporation

Medical - Devices

HealthcareNASDAQ • US
Market Cap$6.66B
5Y Perf.+1.0%

KMDA vs GRFS vs CSL vs BIO vs BRKR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
KMDA logoKMDA
GRFS logoGRFS
CSL logoCSL
BIO logoBIO
BRKR logoBRKR
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - GeneralConstructionMedical - DevicesMedical - Devices
Market Cap$476M$6.82B$14.73B$6.95B$6.66B
Revenue (TTM)$181M$7.51B$4.98B$2.59B$3.46B
Net Income (TTM)$20M$401M$725M$169M$-12M
Gross Margin42.3%38.4%35.6%51.9%45.3%
Operating Margin14.5%17.0%20.1%9.2%4.9%
Forward P/E16.4x9.2x17.2x25.0x20.7x
Total Debt$12M$8.74B$2.88B$1.53B$2.04B
Cash & Equiv.$75M$825M$1.11B$532M$299M

KMDA vs GRFS vs CSL vs BIO vs BRKRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

KMDA
GRFS
CSL
BIO
BRKR
StockMay 20May 26Return
Kamada Ltd. (KMDA)100105.2+5.2%
Grifols, S.A. (GRFS)10042.6-57.4%
Carlisle Companies … (CSL)100300.7+200.7%
Bio-Rad Laboratorie… (BIO)10052.4-47.6%
Bruker Corporation (BRKR)100101.0+1.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: KMDA vs GRFS vs CSL vs BIO vs BRKR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KMDA and GRFS are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Grifols, S.A. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. CSL and BIO also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
KMDA
Kamada Ltd.
The Growth Play

KMDA has the current edge in this matchup, primarily because of its strength in growth exposure.

  • Rev growth 21.4%, EPS growth 48.0%, 3Y rev CAGR 14.7%
  • 21.4% revenue growth vs GRFS's 0.2%
  • +25.0% vs CSL's -5.1%
Best for: growth exposure
GRFS
Grifols, S.A.
The Income Pick

GRFS is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.

  • Dividend streak 2 yrs, beta 1.12, yield 2.6%
  • Beta 1.12, yield 2.6%, current ratio 2.51x
  • Lower P/E (9.2x vs 20.7x)
  • 2.6% yield, 2-year raise streak, vs CSL's 1.2%, (1 stock pays no dividend)
Best for: income & stability and defensive
CSL
Carlisle Companies Incorporated
The Long-Run Compounder

CSL ranks third and is worth considering specifically for long-term compounding.

  • 277.4% 10Y total return vs KMDA's 123.9%
  • 14.6% margin vs BRKR's -0.3%
  • 12.0% ROA vs BRKR's -0.2%, ROIC 20.6% vs 4.4%
Best for: long-term compounding
BIO
Bio-Rad Laboratories, Inc.
The Defensive Pick

BIO is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.92, Low D/E 20.5%, current ratio 5.62x
  • Beta 0.92 vs BRKR's 1.59, lower leverage
Best for: sleep-well-at-night
BRKR
Bruker Corporation
The Healthcare Pick

Among these 5 stocks, BRKR doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthKMDA logoKMDA21.4% revenue growth vs GRFS's 0.2%
ValueGRFS logoGRFSLower P/E (9.2x vs 20.7x)
Quality / MarginsCSL logoCSL14.6% margin vs BRKR's -0.3%
Stability / SafetyBIO logoBIOBeta 0.92 vs BRKR's 1.59, lower leverage
DividendsGRFS logoGRFS2.6% yield, 2-year raise streak, vs CSL's 1.2%, (1 stock pays no dividend)
Momentum (1Y)KMDA logoKMDA+25.0% vs CSL's -5.1%
Efficiency (ROA)CSL logoCSL12.0% ROA vs BRKR's -0.2%, ROIC 20.6% vs 4.4%

KMDA vs GRFS vs CSL vs BIO vs BRKR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

KMDAKamada Ltd.
FY 2025
Distribution Member
100.0%$24M
GRFSGrifols, S.A.
FY 2025
Haemoderivatives
86.2%$6.5B
Transfusional medicine
8.3%$623M
Other Product
3.2%$243M
Bio supplies
2.0%$154M
Other diagnostic
0.2%$17M
CSLCarlisle Companies Incorporated
FY 2025
Reportable Segments
50.0%$5.0B
Construction Materials
37.1%$3.7B
Carlisle Weatherproofing Technologies
12.9%$1.3B
BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B
BRKRBruker Corporation
FY 2025
Product
80.5%$2.8B
Product and Service, Other
19.5%$670M

KMDA vs GRFS vs CSL vs BIO vs BRKR — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKMDALAGGINGBRKR

Income & Cash Flow (Last 12 Months)

CSL leads this category, winning 3 of 6 comparable metrics.

GRFS is the larger business by revenue, generating $7.5B annually — 41.4x KMDA's $181M. CSL is the more profitable business, keeping 14.6% of every revenue dollar as net income compared to BRKR's -0.3%. On growth, KMDA holds the edge at +16.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricKMDA logoKMDAKamada Ltd.GRFS logoGRFSGrifols, S.A.CSL logoCSLCarlisle Companie…BIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
RevenueTrailing 12 months$181M$7.5B$5.0B$2.6B$3.5B
EBITDAEarnings before interest/tax$41M$1.6B$1.1B-$315M$397M
Net IncomeAfter-tax profit$20M$401M$725M$169M-$12M
Free Cash FlowCash after capex$16M$772M$925M$357M$51M
Gross MarginGross profit ÷ Revenue+42.3%+38.4%+35.6%+51.9%+45.3%
Operating MarginEBIT ÷ Revenue+14.5%+17.0%+20.1%+9.2%+4.9%
Net MarginNet income ÷ Revenue+11.2%+5.3%+14.6%+6.5%-0.3%
FCF MarginFCF ÷ Revenue+8.7%+10.3%+18.6%+13.8%+1.5%
Rev. Growth (YoY)Latest quarter vs prior year+16.9%-0.6%-4.0%+1.1%+2.7%
EPS Growth (YoY)Latest quarter vs prior year-15.7%+40.0%-3.1%-9.5%-79.2%
CSL leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

GRFS leads this category, winning 5 of 6 comparable metrics.

At 9.2x trailing earnings, BIO trades at a 59% valuation discount to KMDA's 22.3x P/E. On an enterprise value basis, GRFS's 8.5x EV/EBITDA is more attractive than BRKR's 18.4x.

MetricKMDA logoKMDAKamada Ltd.GRFS logoGRFSGrifols, S.A.CSL logoCSLCarlisle Companie…BIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
Market CapShares × price$476M$6.8B$14.7B$6.9B$6.7B
Enterprise ValueMkt cap + debt − cash$413M$16.1B$16.5B$7.9B$8.4B
Trailing P/EPrice ÷ TTM EPS22.32x12.03x21.05x9.23x-291.53x
Forward P/EPrice ÷ next-FY EPS est.16.36x9.20x17.18x25.00x20.68x
PEG RatioP/E ÷ EPS growth rate0.87x
EV / EBITDAEnterprise value multiple9.26x8.47x13.79x16.70x18.41x
Price / SalesMarket cap ÷ Revenue2.44x0.80x2.94x2.69x1.94x
Price / BookPrice ÷ Book value/share1.79x0.61x8.67x0.94x2.64x
Price / FCFMarket cap ÷ FCF28.14x7.72x15.18x18.55x153.73x
GRFS leads this category, winning 5 of 6 comparable metrics.

Profitability & Efficiency

KMDA leads this category, winning 5 of 9 comparable metrics.

CSL delivers a 34.5% return on equity — every $100 of shareholder capital generates $34 in annual profit, vs $-0 for BRKR. KMDA carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to CSL's 1.60x. On the Piotroski fundamental quality scale (0–9), KMDA scores 6/9 vs BRKR's 4/9, reflecting solid financial health.

MetricKMDA logoKMDAKamada Ltd.GRFS logoGRFSGrifols, S.A.CSL logoCSLCarlisle Companie…BIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
ROE (TTM)Return on equity+7.8%+5.2%+34.5%+2.4%-0.5%
ROA (TTM)Return on assets+5.4%+2.0%+12.0%+2.2%-0.2%
ROICReturn on invested capital+10.7%+5.4%+20.6%+2.6%+4.4%
ROCEReturn on capital employed+8.7%+6.4%+18.7%+2.9%+5.0%
Piotroski ScoreFundamental quality 0–966554
Debt / EquityFinancial leverage0.04x1.15x1.60x0.21x0.81x
Net DebtTotal debt minus cash-$64M$7.9B$1.8B$999M$1.7B
Cash & Equiv.Liquid assets$75M$825M$1.1B$532M$299M
Total DebtShort + long-term debt$12M$8.7B$2.9B$1.5B$2.0B
Interest CoverageEBIT ÷ Interest expense26.41x2.05x11.06x-2.49x1.14x
KMDA leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

KMDA leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in CSL five years ago would be worth $19,505 today (with dividends reinvested), compared to $4,232 for BIO. Over the past 12 months, KMDA leads with a +25.0% total return vs CSL's -5.1%. The 3-year compound annual growth rate (CAGR) favors KMDA at 20.8% vs BRKR's -16.9% — a key indicator of consistent wealth creation.

MetricKMDA logoKMDAKamada Ltd.GRFS logoGRFSGrifols, S.A.CSL logoCSLCarlisle Companie…BIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
YTD ReturnYear-to-date+21.1%-12.8%+10.1%-15.7%-9.0%
1-Year ReturnPast 12 months+25.0%+12.5%-5.1%+10.7%+7.8%
3-Year ReturnCumulative with dividends+76.3%+8.9%+75.5%-32.0%-42.5%
5-Year ReturnCumulative with dividends+42.3%-52.8%+95.1%-57.7%-35.5%
10-Year ReturnCumulative with dividends+123.9%-35.4%+277.4%+81.4%+67.1%
CAGR (3Y)Annualised 3-year return+20.8%+2.9%+20.6%-12.1%-16.9%
KMDA leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — KMDA and BIO each lead in 1 of 2 comparable metrics.

BIO is the less volatile stock with a 0.92 beta — it tends to amplify market swings less than BRKR's 1.59 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KMDA currently trades 88.3% from its 52-week high vs GRFS's 72.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricKMDA logoKMDAKamada Ltd.GRFS logoGRFSGrifols, S.A.CSL logoCSLCarlisle Companie…BIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
Beta (5Y)Sensitivity to S&P 5001.17x1.12x1.12x0.92x1.59x
52-Week HighHighest price in past year$9.35$11.14$435.92$343.12$56.22
52-Week LowLowest price in past year$6.50$7.09$293.43$211.43$28.53
% of 52W HighCurrent price vs 52-week peak+88.3%+72.4%+82.7%+75.0%+77.8%
RSI (14)Momentum oscillator 0–10048.954.661.037.064.8
Avg Volume (50D)Average daily shares traded59K714K386K306K1.9M
Evenly matched — KMDA and BIO each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — GRFS and CSL each lead in 1 of 2 comparable metrics.

Analyst consensus: KMDA as "Buy", GRFS as "Buy", CSL as "Buy", BIO as "Buy", BRKR as "Buy". Consensus price targets imply 45.3% upside for KMDA (target: $12) vs 13.4% for CSL (target: $409). For income investors, GRFS offers the higher dividend yield at 2.63% vs BRKR's 0.34%.

MetricKMDA logoKMDAKamada Ltd.GRFS logoGRFSGrifols, S.A.CSL logoCSLCarlisle Companie…BIO logoBIOBio-Rad Laborator…BRKR logoBRKRBruker Corporation
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$12.00$408.75$312.50$52.13
# AnalystsCovering analysts68261432
Dividend YieldAnnual dividend ÷ price+2.6%+2.6%+1.2%+0.3%
Dividend StreakConsecutive years of raises12370
Dividend / ShareAnnual DPS$0.21$0.18$4.19$0.15
Buyback YieldShare repurchases ÷ mkt cap0.0%+2.1%+8.8%+4.3%+0.2%
Evenly matched — GRFS and CSL each lead in 1 of 2 comparable metrics.
Key Takeaway

KMDA leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). CSL leads in 1 (Income & Cash Flow). 2 tied.

Best OverallKamada Ltd. (KMDA)Leads 2 of 6 categories
Loading custom metrics...

KMDA vs GRFS vs CSL vs BIO vs BRKR: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is KMDA or GRFS or CSL or BIO or BRKR a better buy right now?

For growth investors, Kamada Ltd.

(KMDA) is the stronger pick with 21. 4% revenue growth year-over-year, versus 0. 2% for Grifols, S. A. (GRFS). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 2x trailing P/E (25. 0x forward), making it the more compelling value choice. Analysts rate Kamada Ltd. (KMDA) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — KMDA or GRFS or CSL or BIO or BRKR?

On trailing P/E, Bio-Rad Laboratories, Inc.

(BIO) is the cheapest at 9. 2x versus Kamada Ltd. at 22. 3x. On forward P/E, Grifols, S. A. is actually cheaper at 9. 2x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — KMDA or GRFS or CSL or BIO or BRKR?

Over the past 5 years, Carlisle Companies Incorporated (CSL) delivered a total return of +95.

1%, compared to -57. 7% for Bio-Rad Laboratories, Inc. (BIO). Over 10 years, the gap is even starker: CSL returned +277. 4% versus GRFS's -35. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — KMDA or GRFS or CSL or BIO or BRKR?

By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.

(BIO) is the lower-risk stock at 0. 92β versus Bruker Corporation's 1. 59β — meaning BRKR is approximately 72% more volatile than BIO relative to the S&P 500. On balance sheet safety, Kamada Ltd. (KMDA) carries a lower debt/equity ratio of 4% versus 160% for Carlisle Companies Incorporated — giving it more financial flexibility in a downturn.

05

Which is growing faster — KMDA or GRFS or CSL or BIO or BRKR?

By revenue growth (latest reported year), Kamada Ltd.

(KMDA) is pulling ahead at 21. 4% versus 0. 2% for Grifols, S. A. (GRFS). On earnings-per-share growth, the picture is similar: Grifols, S. A. grew EPS 147. 8% year-over-year, compared to -119. 7% for Bruker Corporation. Over a 3-year CAGR, KMDA leads at 14. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — KMDA or GRFS or CSL or BIO or BRKR?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus -0. 3% for Bruker Corporation — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CSL leads at 19. 9% versus 6. 9% for BRKR. At the gross margin level — before operating expenses — BIO leads at 52. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is KMDA or GRFS or CSL or BIO or BRKR more undervalued right now?

On forward earnings alone, Grifols, S.

A. (GRFS) trades at 9. 2x forward P/E versus 25. 0x for Bio-Rad Laboratories, Inc. — 15. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for KMDA: 45. 3% to $12. 00.

08

Which pays a better dividend — KMDA or GRFS or CSL or BIO or BRKR?

In this comparison, GRFS (2.

6% yield), KMDA (2. 6% yield), CSL (1. 2% yield), BRKR (0. 3% yield) pay a dividend. BIO does not pay a meaningful dividend and should not be held primarily for income.

09

Is KMDA or GRFS or CSL or BIO or BRKR better for a retirement portfolio?

For long-horizon retirement investors, Carlisle Companies Incorporated (CSL) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.

12), 1. 2% yield, +277. 4% 10Y return). Bruker Corporation (BRKR) carries a higher beta of 1. 59 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CSL: +277. 4%, BRKR: +67. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between KMDA and GRFS and CSL and BIO and BRKR?

These companies operate in different sectors (KMDA (Healthcare) and GRFS (Healthcare) and CSL (Industrials) and BIO (Healthcare) and BRKR (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: KMDA is a small-cap high-growth stock; GRFS is a small-cap deep-value stock; CSL is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock; BRKR is a small-cap quality compounder stock. KMDA, GRFS, CSL pay a dividend while BIO, BRKR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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KMDA

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  • Sector: Healthcare
  • Market Cap > $100B
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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 27%
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Beat Both

Find stocks that outperform KMDA and GRFS and CSL and BIO and BRKR on the metrics below

Revenue Growth>
%
(KMDA: 16.9% · GRFS: -0.6%)
Net Margin>
%
(KMDA: 11.2% · GRFS: 5.3%)
P/E Ratio<
x
(KMDA: 22.3x · GRFS: 12.0x)

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