Biotechnology
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KOD vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
KOD vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $2.31B | $73.68B |
| Revenue (TTM) | $0.00 | $14.92B |
| Net Income (TTM) | $-217M | $4.42B |
| Gross Margin | — | 84.5% |
| Operating Margin | — | 24.3% |
| Forward P/E | — | 15.3x |
| Total Debt | $70M | $2.71B |
| Cash & Equiv. | $168M | $3.12B |
KOD vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Kodiak Sciences Inc. (KOD) | 100 | 338.1 | +238.1% |
| Regeneron Pharmaceu… (REGN) | 100 | 115.7 | +15.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KOD vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
KOD is the clearest fit if your priority is growth exposure and long-term compounding.
- EPS growth 32.6%
- 20.5% 10Y total return vs REGN's 90.0%
- +10.3% vs REGN's +27.1%
REGN carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- Dividend streak 1 yrs, beta 0.81, yield 0.5%
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- Beta 0.81, yield 0.5%, current ratio 4.13x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 1.0% revenue growth vs KOD's -15.7% | |
| Quality / Margins | 29.6% margin vs KOD's 3.3% | |
| Stability / Safety | Beta 0.81 vs KOD's 1.81, lower leverage | |
| Dividends | 0.5% yield; 1-year raise streak; the other pay no meaningful dividend | |
| Momentum (1Y) | +10.3% vs REGN's +27.1% | |
| Efficiency (ROA) | 11.1% ROA vs KOD's -99.7%, ROIC 8.9% vs -130.7% |
KOD vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
KOD vs REGN — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
REGN leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
REGN and KOD operate at a comparable scale, with $14.9B and $0 in trailing revenue.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $0 | $14.9B |
| EBITDAEarnings before interest/tax | -$195M | $4.2B |
| Net IncomeAfter-tax profit | -$217M | $4.4B |
| Free Cash FlowCash after capex | -$127M | $4.2B |
| Gross MarginGross profit ÷ Revenue | — | +84.5% |
| Operating MarginEBIT ÷ Revenue | — | +24.3% |
| Net MarginNet income ÷ Revenue | — | +29.6% |
| FCF MarginFCF ÷ Revenue | — | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -38.1% | -7.2% |
Valuation Metrics
Evenly matched — KOD and REGN each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $2.3B | $73.7B |
| Enterprise ValueMkt cap + debt − cash | $2.2B | $73.3B |
| Trailing P/EPrice ÷ TTM EPS | -13.04x | 17.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 15.35x |
| PEG RatioP/E ÷ EPS growth rate | — | 2.70x |
| EV / EBITDAEnterprise value multiple | — | 17.78x |
| Price / SalesMarket cap ÷ Revenue | — | 5.14x |
| Price / BookPrice ÷ Book value/share | 15.28x | 2.46x |
| Price / FCFMarket cap ÷ FCF | — | 18.06x |
Profitability & Efficiency
REGN leads this category, winning 7 of 8 comparable metrics.
Profitability & Efficiency
REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-9 for KOD. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to KOD's 0.47x. On the Piotroski fundamental quality scale (0–9), REGN scores 5/9 vs KOD's 3/9, reflecting solid financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -9.2% | +14.3% |
| ROA (TTM)Return on assets | -99.7% | +11.1% |
| ROICReturn on invested capital | -130.7% | +8.9% |
| ROCEReturn on capital employed | -50.0% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 |
| Debt / EquityFinancial leverage | 0.47x | 0.09x |
| Net DebtTotal debt minus cash | -$98M | -$412M |
| Cash & Equiv.Liquid assets | $168M | $3.1B |
| Total DebtShort + long-term debt | $70M | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | — | 108.44x |
Total Returns (Dividends Reinvested)
KOD leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KOD five years ago would be worth $21,496 today (with dividends reinvested), compared to $14,365 for REGN. Over the past 12 months, KOD leads with a +1028.7% total return vs REGN's +27.1%. The 3-year compound annual growth rate (CAGR) favors KOD at 107.8% vs REGN's -1.7% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +67.9% | -8.5% |
| 1-Year ReturnPast 12 months | +1028.7% | +27.1% |
| 3-Year ReturnCumulative with dividends | +796.9% | -5.1% |
| 5-Year ReturnCumulative with dividends | +115.0% | +43.6% |
| 10-Year ReturnCumulative with dividends | +2051.7% | +90.0% |
| CAGR (3Y)Annualised 3-year return | +107.8% | -1.7% |
Risk & Volatility
Evenly matched — KOD and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than KOD's 1.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KOD currently trades 91.3% from its 52-week high vs REGN's 86.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.81x | 0.81x |
| 52-Week HighHighest price in past year | $47.84 | $821.11 |
| 52-Week LowLowest price in past year | $2.81 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +91.3% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 61.7 | 44.9 |
| Avg Volume (50D)Average daily shares traded | 1.1M | 631K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates KOD as "Buy" and REGN as "Buy". Consensus price targets imply 48.1% upside for KOD (target: $65) vs 22.1% for REGN (target: $866). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $64.67 | $865.68 |
| # AnalystsCovering analysts | 18 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +0.5% |
| Dividend StreakConsecutive years of raises | — | 1 |
| Dividend / ShareAnnual DPS | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.4% |
REGN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). KOD leads in 1 (Total Returns). 2 tied.
KOD vs REGN: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is KOD or REGN a better buy right now?
Regeneron Pharmaceuticals, Inc.
(REGN) offers the better valuation at 17. 1x trailing P/E (15. 3x forward), making it the more compelling value choice. Analysts rate Kodiak Sciences Inc. (KOD) a "Buy" — based on 18 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — KOD or REGN?
Over the past 5 years, Kodiak Sciences Inc.
(KOD) delivered a total return of +115. 0%, compared to +43. 6% for Regeneron Pharmaceuticals, Inc. (REGN). Over 10 years, the gap is even starker: KOD returned +20. 5% versus REGN's +90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — KOD or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.
(REGN) is the lower-risk stock at 0. 81β versus Kodiak Sciences Inc. 's 1. 81β — meaning KOD is approximately 125% more volatile than REGN relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 47% for Kodiak Sciences Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — KOD or REGN?
On earnings-per-share growth, the picture is similar: Kodiak Sciences Inc.
grew EPS 32. 6% year-over-year, compared to 8. 2% for Regeneron Pharmaceuticals, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — KOD or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus 0. 0% for Kodiak Sciences Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: REGN leads at 24. 9% versus 0. 0% for KOD. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is KOD or REGN more undervalued right now?
Analyst consensus price targets imply the most upside for KOD: 48.
1% to $64. 67.
07Which pays a better dividend — KOD or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. KOD does not pay a meaningful dividend and should not be held primarily for income.
08Is KOD or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Kodiak Sciences Inc. (KOD) carries a higher beta of 1. 81 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (REGN: +90. 0%, KOD: +20. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between KOD and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: KOD is a small-cap quality compounder stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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