Biotechnology
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5 / 10Stock Comparison
KYTX vs CABA vs AUTL vs IMVT vs BEAM
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
KYTX vs CABA vs AUTL vs IMVT vs BEAM — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $407M | $409M | $410M | $5.53B | $3.23B |
| Revenue (TTM) | $0.00 | $0.00 | $51M | $0.00 | $132M |
| Net Income (TTM) | $-161M | $-168M | $-225M | $-464M | $-65M |
| Gross Margin | — | — | -309.4% | — | -64.2% |
| Operating Margin | — | — | -8.6% | — | -281.0% |
| Total Debt | $8M | $27M | $53M | $98K | $294M |
| Cash & Equiv. | $97M | $83M | $227M | $714M | $295M |
KYTX vs CABA vs AUTL vs IMVT vs BEAM — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 24 | May 26 | Return |
|---|---|---|---|
| Kyverna Therapeutic… (KYTX) | 100 | 34.2 | -65.8% |
| Cabaletta Bio, Inc. (CABA) | 100 | 17.5 | -82.5% |
| Autolus Therapeutic… (AUTL) | 100 | 26.8 | -73.3% |
| Immunovant, Inc. (IMVT) | 100 | 77.0 | -23.0% |
| Beam Therapeutics I… (BEAM) | 100 | 79.7 | -20.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KYTX vs CABA vs AUTL vs IMVT vs BEAM
Each card shows where this stock fits in a portfolio — not just who wins on paper.
KYTX carries the broadest edge in this set and is the clearest fit for quality and momentum.
- 5.0% margin vs AUTL's -439.7%
- +360.4% vs AUTL's +30.5%
Among these 5 stocks, CABA doesn't own a clear edge in any measured category.
AUTL is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 496.0%, EPS growth 27.5%, 3Y rev CAGR 88.7%
- 496.0% revenue growth vs KYTX's -91.8%
IMVT ranks third and is worth considering specifically for income & stability and long-term compounding.
- beta 1.37
- 173.6% 10Y total return vs BEAM's 67.8%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
BEAM is the clearest fit if your priority is efficiency.
- -4.6% ROA vs CABA's -90.2%, ROIC -31.1% vs -429.6%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 496.0% revenue growth vs KYTX's -91.8% | |
| Quality / Margins | 5.0% margin vs AUTL's -439.7% | |
| Stability / Safety | Beta 1.37 vs KYTX's 3.05, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +360.4% vs AUTL's +30.5% | |
| Efficiency (ROA) | -4.6% ROA vs CABA's -90.2%, ROIC -31.1% vs -429.6% |
KYTX vs CABA vs AUTL vs IMVT vs BEAM — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
KYTX vs CABA vs AUTL vs IMVT vs BEAM — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BEAM leads in 3 of 6 categories
IMVT leads 1 • KYTX leads 0 • CABA leads 0 • AUTL leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
BEAM leads this category, winning 4 of 5 comparable metrics.
Income & Cash Flow (Last 12 Months)
BEAM and IMVT operate at a comparable scale, with $132M and $0 in trailing revenue. Profitability is closely matched — net margins range from -49.2% (BEAM) to -4.4% (AUTL).
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $51M | $0 | $132M |
| EBITDAEarnings before interest/tax | -$170M | -$172M | -$427M | -$487M | -$355M |
| Net IncomeAfter-tax profit | -$161M | -$168M | -$225M | -$464M | -$65M |
| Free Cash FlowCash after capex | -$158M | -$132M | -$278M | -$423M | -$384M |
| Gross MarginGross profit ÷ Revenue | — | — | -3.1% | — | -64.2% |
| Operating MarginEBIT ÷ Revenue | — | — | -8.6% | — | -2.8% |
| Net MarginNet income ÷ Revenue | — | — | -4.4% | — | -49.2% |
| FCF MarginFCF ÷ Revenue | — | — | -5.4% | — | -2.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | — | -100.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -6.3% | +36.9% | +3.2% | +19.7% | +26.6% |
Valuation Metrics
BEAM leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $407M | $409M | $410M | $5.5B | $3.2B |
| Enterprise ValueMkt cap + debt − cash | $319M | $353M | $235M | $4.8B | $3.2B |
| Trailing P/EPrice ÷ TTM EPS | -2.79x | -2.44x | -1.84x | -9.97x | -38.85x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | 40.47x | — | 23.14x |
| Price / BookPrice ÷ Book value/share | 1.34x | 3.65x | 0.96x | 5.83x | 2.51x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
BEAM leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
BEAM delivers a -5.9% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-122 for CABA. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CABA's 0.24x. On the Piotroski fundamental quality scale (0–9), KYTX scores 5/9 vs CABA's 1/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -106.0% | -121.7% | -84.7% | -47.1% | -5.9% |
| ROA (TTM)Return on assets | -86.0% | -90.2% | -34.0% | -44.1% | -4.6% |
| ROICReturn on invested capital | -106.0% | -4.3% | -2.0% | — | -31.1% |
| ROCEReturn on capital employed | -87.4% | -126.2% | -45.9% | -66.1% | -33.3% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 1 | 5 | 2 | 4 |
| Debt / EquityFinancial leverage | 0.03x | 0.24x | 0.12x | 0.00x | 0.24x |
| Net DebtTotal debt minus cash | -$88M | -$56M | -$175M | -$714M | -$1M |
| Cash & Equiv.Liquid assets | $97M | $83M | $227M | $714M | $295M |
| Total DebtShort + long-term debt | $8M | $27M | $53M | $98,000 | $294M |
| Interest CoverageEBIT ÷ Interest expense | -2204.37x | — | -25.98x | — | 1.08x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $2,989 for AUTL. Over the past 12 months, KYTX leads with a +360.4% total return vs AUTL's +30.5%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs KYTX's -32.3% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +6.0% | +81.0% | -14.2% | +5.1% | +16.0% |
| 1-Year ReturnPast 12 months | +360.4% | +244.8% | +30.5% | +96.1% | +93.9% |
| 3-Year ReturnCumulative with dividends | -69.0% | -65.8% | -14.6% | +40.9% | -5.6% |
| 5-Year ReturnCumulative with dividends | -69.0% | -58.2% | -70.1% | +62.4% | -55.6% |
| 10-Year ReturnCumulative with dividends | -69.0% | -60.0% | -93.6% | +173.6% | +67.8% |
| CAGR (3Y)Annualised 3-year return | -32.3% | -30.1% | -5.1% | +12.1% | -1.9% |
Risk & Volatility
Evenly matched — CABA and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than KYTX's 3.05 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. CABA currently trades 94.6% from its 52-week high vs AUTL's 59.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 3.05x | 2.54x | 1.95x | 1.37x | 2.14x |
| 52-Week HighHighest price in past year | $13.67 | $4.23 | $2.70 | $30.09 | $36.44 |
| 52-Week LowLowest price in past year | $1.95 | $1.11 | $1.15 | $13.36 | $15.35 |
| % of 52W HighCurrent price vs 52-week peak | +68.0% | +94.6% | +59.4% | +90.5% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 54.2 | 60.8 | 64.3 | 60.2 | 60.9 |
| Avg Volume (50D)Average daily shares traded | 869K | 2.8M | 1.6M | 1.4M | 2.0M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: KYTX as "Buy", CABA as "Buy", AUTL as "Buy", IMVT as "Buy", BEAM as "Buy". Consensus price targets imply 452.6% upside for AUTL (target: $9) vs 29.7% for BEAM (target: $41).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $32.67 | $16.33 | $8.87 | $45.50 | $40.83 |
| # AnalystsCovering analysts | 4 | 12 | 14 | 23 | 27 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 1 | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.1% | 0.0% | 0.0% | 0.0% |
BEAM leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). IMVT leads in 1 (Total Returns). 1 tied.
KYTX vs CABA vs AUTL vs IMVT vs BEAM: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is KYTX or CABA or AUTL or IMVT or BEAM a better buy right now?
For growth investors, Autolus Therapeutics plc (AUTL) is the stronger pick with 496.
0% revenue growth year-over-year, versus 120. 0% for Beam Therapeutics Inc. (BEAM). Analysts rate Kyverna Therapeutics, Inc. (KYTX) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — KYTX or CABA or AUTL or IMVT or BEAM?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -70. 1% for Autolus Therapeutics plc (AUTL). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus AUTL's -93. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — KYTX or CABA or AUTL or IMVT or BEAM?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus Kyverna Therapeutics, Inc. 's 3. 05β — meaning KYTX is approximately 122% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 24% for Cabaletta Bio, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — KYTX or CABA or AUTL or IMVT or BEAM?
By revenue growth (latest reported year), Autolus Therapeutics plc (AUTL) is pulling ahead at 496.
0% versus 120. 0% for Beam Therapeutics Inc. (BEAM). On earnings-per-share growth, the picture is similar: Beam Therapeutics Inc. grew EPS 82. 3% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, AUTL leads at 88. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — KYTX or CABA or AUTL or IMVT or BEAM?
Kyverna Therapeutics, Inc.
(KYTX) is the more profitable company, earning 0. 0% net margin versus -21. 8% for Autolus Therapeutics plc — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KYTX leads at 0. 0% versus -23. 9% for AUTL. At the gross margin level — before operating expenses — BEAM leads at 84. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — KYTX or CABA or AUTL or IMVT or BEAM?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is KYTX or CABA or AUTL or IMVT or BEAM better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Kyverna Therapeutics, Inc. (KYTX) carries a higher beta of 3. 05 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, KYTX: -69. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between KYTX and CABA and AUTL and IMVT and BEAM?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: KYTX is a small-cap quality compounder stock; CABA is a small-cap quality compounder stock; AUTL is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; BEAM is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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