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Stock Comparison

LFMD vs NUVB vs KYMR vs HIMS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
LFMD
LifeMD, Inc.

Medical - Pharmaceuticals

HealthcareNASDAQ • US
Market Cap$215M
5Y Perf.-33.5%
NUVB
Nuvation Bio Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$1.67B
5Y Perf.-51.8%
KYMR
Kymera Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.91B
5Y Perf.+165.3%
HIMS
Hims & Hers Health, Inc.

Medical - Equipment & Services

HealthcareNYSE • US
Market Cap$6.63B
5Y Perf.+144.9%

LFMD vs NUVB vs KYMR vs HIMS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
LFMD logoLFMD
NUVB logoNUVB
KYMR logoKYMR
HIMS logoHIMS
IndustryMedical - PharmaceuticalsBiotechnologyBiotechnologyMedical - Equipment & Services
Market Cap$215M$1.67B$6.91B$6.63B
Revenue (TTM)$219M$143M$51M$2.35B
Net Income (TTM)$-17M$-146M$-315M$128M
Gross Margin86.7%91.6%33.2%69.7%
Operating Margin-5.9%-105.0%-7.0%4.6%
Forward P/E51.5x
Total Debt$6M$10M$82M$1.12B
Cash & Equiv.$37M$164M$357M$229M

LFMD vs NUVB vs KYMR vs HIMSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

LFMD
NUVB
KYMR
HIMS
StockAug 20May 26Return
LifeMD, Inc. (LFMD)10066.5-33.5%
Nuvation Bio Inc. (NUVB)10048.2-51.8%
Kymera Therapeutics… (KYMR)100265.3+165.3%
Hims & Hers Health,… (HIMS)100244.9+144.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: LFMD vs NUVB vs KYMR vs HIMS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: LFMD and KYMR are tied at the top with 2 categories each — the right choice depends on your priorities. Kymera Therapeutics, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. HIMS and NUVB also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
LFMD
LifeMD, Inc.
The Value Play

LFMD has the current edge in this matchup, primarily because of its strength in value and dividends.

  • Better valuation composite
  • 1.5% yield; the other 3 pay no meaningful dividend
Best for: value and dividends
NUVB
Nuvation Bio Inc.
The Growth Play

NUVB is the clearest fit if your priority is growth exposure.

  • Rev growth 7.0%, EPS growth 71.6%
  • 7.0% revenue growth vs KYMR's -16.7%
Best for: growth exposure
KYMR
Kymera Therapeutics, Inc.
The Income Pick

KYMR is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 1.15
  • Lower volatility, beta 1.15, Low D/E 5.2%, current ratio 10.47x
  • Beta 1.15, current ratio 10.47x
  • Beta 1.15 vs HIMS's 2.40, lower leverage
Best for: income & stability and sleep-well-at-night
HIMS
Hims & Hers Health, Inc.
The Long-Run Compounder

HIMS is the clearest fit if your priority is long-term compounding.

  • 161.9% 10Y total return vs LFMD's 220.7%
  • 5.5% margin vs KYMR's -6.1%
  • 6.0% ROA vs LFMD's -24.3%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthNUVB logoNUVB7.0% revenue growth vs KYMR's -16.7%
ValueLFMD logoLFMDBetter valuation composite
Quality / MarginsHIMS logoHIMS5.5% margin vs KYMR's -6.1%
Stability / SafetyKYMR logoKYMRBeta 1.15 vs HIMS's 2.40, lower leverage
DividendsLFMD logoLFMD1.5% yield; the other 3 pay no meaningful dividend
Momentum (1Y)KYMR logoKYMR+190.7% vs HIMS's -51.0%
Efficiency (ROA)HIMS logoHIMS6.0% ROA vs LFMD's -24.3%

LFMD vs NUVB vs KYMR vs HIMS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

LFMDLifeMD, Inc.
FY 2025
Product and Services
100.0%$13M
NUVBNuvation Bio Inc.
FY 2025
License
60.8%$38M
Product
39.2%$25M
KYMRKymera Therapeutics, Inc.

Segment breakdown not available.

HIMSHims & Hers Health, Inc.

Segment breakdown not available.

LFMD vs NUVB vs KYMR vs HIMS — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKYMRLAGGINGLFMD

Income & Cash Flow (Last 12 Months)

NUVB leads this category, winning 3 of 6 comparable metrics.

HIMS is the larger business by revenue, generating $2.3B annually — 45.6x KYMR's $51M. HIMS is the more profitable business, keeping 5.5% of every revenue dollar as net income compared to KYMR's -6.1%. On growth, NUVB holds the edge at +26.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricLFMD logoLFMDLifeMD, Inc.NUVB logoNUVBNuvation Bio Inc.KYMR logoKYMRKymera Therapeuti…HIMS logoHIMSHims & Hers Healt…
RevenueTrailing 12 months$219M$143M$51M$2.3B
EBITDAEarnings before interest/tax-$5M-$145M-$352M$164M
Net IncomeAfter-tax profit-$17M-$146M-$315M$128M
Free Cash FlowCash after capex$15M-$126M-$244M$73M
Gross MarginGross profit ÷ Revenue+86.7%+91.6%+33.2%+69.7%
Operating MarginEBIT ÷ Revenue-5.9%-105.0%-7.0%+4.6%
Net MarginNet income ÷ Revenue-7.8%-102.1%-6.1%+5.5%
FCF MarginFCF ÷ Revenue+6.8%-88.1%-4.7%+3.1%
Rev. Growth (YoY)Latest quarter vs prior year-23.6%+26.0%+55.5%+28.4%
EPS Growth (YoY)Latest quarter vs prior year-16.0%+106.3%+13.4%-27.3%
NUVB leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — LFMD and KYMR each lead in 2 of 4 comparable metrics.
MetricLFMD logoLFMDLifeMD, Inc.NUVB logoNUVBNuvation Bio Inc.KYMR logoKYMRKymera Therapeuti…HIMS logoHIMSHims & Hers Healt…
Market CapShares × price$215M$1.7B$6.9B$6.6B
Enterprise ValueMkt cap + debt − cash$185M$1.5B$6.6B$7.5B
Trailing P/EPrice ÷ TTM EPS-19.52x-8.03x-22.93x50.32x
Forward P/EPrice ÷ next-FY EPS est.51.51x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple42.68x
Price / SalesMarket cap ÷ Revenue1.11x26.61x176.26x2.82x
Price / BookPrice ÷ Book value/share8.75x5.38x4.52x12.25x
Price / FCFMarket cap ÷ FCF33.61x89.61x
Evenly matched — LFMD and KYMR each lead in 2 of 4 comparable metrics.

Profitability & Efficiency

HIMS leads this category, winning 4 of 9 comparable metrics.

HIMS delivers a 23.7% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-162 for LFMD. NUVB carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to HIMS's 2.07x. On the Piotroski fundamental quality scale (0–9), LFMD scores 5/9 vs HIMS's 4/9, reflecting solid financial health.

MetricLFMD logoLFMDLifeMD, Inc.NUVB logoNUVBNuvation Bio Inc.KYMR logoKYMRKymera Therapeuti…HIMS logoHIMSHims & Hers Healt…
ROE (TTM)Return on equity-162.4%-44.1%-25.0%+23.7%
ROA (TTM)Return on assets-24.3%-23.8%-22.3%+6.0%
ROICReturn on invested capital-54.3%-24.9%+10.7%
ROCEReturn on capital employed-37.4%-42.8%-27.2%+10.9%
Piotroski ScoreFundamental quality 0–95444
Debt / EquityFinancial leverage0.27x0.03x0.05x2.07x
Net DebtTotal debt minus cash-$30M-$154M-$275M$892M
Cash & Equiv.Liquid assets$37M$164M$357M$229M
Total DebtShort + long-term debt$6M$10M$82M$1.1B
Interest CoverageEBIT ÷ Interest expense-6.48x-162.11x-2119.53x
HIMS leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

KYMR leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in HIMS five years ago would be worth $23,764 today (with dividends reinvested), compared to $4,173 for NUVB. Over the past 12 months, KYMR leads with a +190.7% total return vs HIMS's -51.0%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs HIMS's 29.4% — a key indicator of consistent wealth creation.

MetricLFMD logoLFMDLifeMD, Inc.NUVB logoNUVBNuvation Bio Inc.KYMR logoKYMRKymera Therapeuti…HIMS logoHIMSHims & Hers Healt…
YTD ReturnYear-to-date+28.7%-43.8%+16.3%-23.2%
1-Year ReturnPast 12 months-43.9%+136.3%+190.7%-51.0%
3-Year ReturnCumulative with dividends+178.9%+197.5%+205.1%+116.6%
5-Year ReturnCumulative with dividends-45.8%-58.3%+92.1%+137.6%
10-Year ReturnCumulative with dividends+220.7%-51.8%+154.4%+161.9%
CAGR (3Y)Annualised 3-year return+40.8%+43.8%+45.0%+29.4%
KYMR leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

KYMR leads this category, winning 2 of 2 comparable metrics.

KYMR is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than HIMS's 2.40 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KYMR currently trades 82.2% from its 52-week high vs LFMD's 28.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricLFMD logoLFMDLifeMD, Inc.NUVB logoNUVBNuvation Bio Inc.KYMR logoKYMRKymera Therapeuti…HIMS logoHIMSHims & Hers Healt…
Beta (5Y)Sensitivity to S&P 5002.12x2.04x1.15x2.40x
52-Week HighHighest price in past year$15.84$9.75$103.00$70.43
52-Week LowLowest price in past year$2.56$1.57$28.06$13.74
% of 52W HighCurrent price vs 52-week peak+28.3%+49.4%+82.2%+36.4%
RSI (14)Momentum oscillator 0–10070.859.154.154.5
Avg Volume (50D)Average daily shares traded1.3M4.3M602K34.9M
KYMR leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: LFMD as "Buy", NUVB as "Buy", KYMR as "Buy", HIMS as "Hold". Consensus price targets imply 157.3% upside for NUVB (target: $12) vs 15.6% for HIMS (target: $30). LFMD is the only dividend payer here at 1.53% yield — a key consideration for income-focused portfolios.

MetricLFMD logoLFMDLifeMD, Inc.NUVB logoNUVBNuvation Bio Inc.KYMR logoKYMRKymera Therapeuti…HIMS logoHIMSHims & Hers Healt…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHold
Price TargetConsensus 12-month target$8.50$12.40$117.06$29.67
# AnalystsCovering analysts1092619
Dividend YieldAnnual dividend ÷ price+1.5%
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS$0.07
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+1.4%
Insufficient data to determine a leader in this category.
Key Takeaway

KYMR leads in 2 of 6 categories (Total Returns, Risk & Volatility). NUVB leads in 1 (Income & Cash Flow). 1 tied.

Best OverallKymera Therapeutics, Inc. (KYMR)Leads 2 of 6 categories
Loading custom metrics...

LFMD vs NUVB vs KYMR vs HIMS: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is LFMD or NUVB or KYMR or HIMS a better buy right now?

For growth investors, Nuvation Bio Inc.

(NUVB) is the stronger pick with 699. 0% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Hims & Hers Health, Inc. (HIMS) offers the better valuation at 50. 3x trailing P/E (51. 5x forward), making it the more compelling value choice. Analysts rate LifeMD, Inc. (LFMD) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — LFMD or NUVB or KYMR or HIMS?

Over the past 5 years, Hims & Hers Health, Inc.

(HIMS) delivered a total return of +137. 6%, compared to -58. 3% for Nuvation Bio Inc. (NUVB). Over 10 years, the gap is even starker: LFMD returned +220. 7% versus NUVB's -51. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — LFMD or NUVB or KYMR or HIMS?

By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.

(KYMR) is the lower-risk stock at 1. 15β versus Hims & Hers Health, Inc. 's 2. 40β — meaning HIMS is approximately 109% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Nuvation Bio Inc. (NUVB) carries a lower debt/equity ratio of 3% versus 2% for Hims & Hers Health, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — LFMD or NUVB or KYMR or HIMS?

By revenue growth (latest reported year), Nuvation Bio Inc.

(NUVB) is pulling ahead at 699. 0% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Nuvation Bio Inc. grew EPS 71. 6% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Over a 3-year CAGR, HIMS leads at 64. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — LFMD or NUVB or KYMR or HIMS?

Hims & Hers Health, Inc.

(HIMS) is the more profitable company, earning 5. 5% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 5. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HIMS leads at 5. 2% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is LFMD or NUVB or KYMR or HIMS more undervalued right now?

Analyst consensus price targets imply the most upside for NUVB: 157.

3% to $12. 40.

07

Which pays a better dividend — LFMD or NUVB or KYMR or HIMS?

In this comparison, LFMD (1.

5% yield) pays a dividend. NUVB, KYMR, HIMS do not pay a meaningful dividend and should not be held primarily for income.

08

Is LFMD or NUVB or KYMR or HIMS better for a retirement portfolio?

For long-horizon retirement investors, Kymera Therapeutics, Inc.

(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), +154. 4% 10Y return). Nuvation Bio Inc. (NUVB) carries a higher beta of 2. 04 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +154. 4%, NUVB: -51. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between LFMD and NUVB and KYMR and HIMS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: LFMD is a small-cap quality compounder stock; NUVB is a small-cap high-growth stock; KYMR is a small-cap quality compounder stock; HIMS is a small-cap high-growth stock. LFMD pays a dividend while NUVB, KYMR, HIMS do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
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  • Market Cap > $100B
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KYMR

High-Growth Disruptor

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  • Revenue Growth > 27%
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