MBX
MBX Biosciences, Inc. Common Stock
Biotechnology
Market Cap$1.55B
5Y Perf.+33.6%
Compare Stocks
2 / 10Try these comparisons:
Stock Comparison
MBX vs PEPG
Revenue, margins, valuation, and 5-year total return — side by side.
PEPG
PepGen Inc.
Biotechnology
Market Cap$123M
5Y Perf.-79.1%
MBX vs PEPG — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | MBX | PEPG |
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $1.55B | $123M |
| Revenue (TTM) | $0.00 | $0.00 |
| Net Income (TTM) | $-80M | $-90M |
| Total Debt | $171K | $17M |
| Cash & Equiv. | $49M | $61M |
MBX vs PEPG — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
MBX
PEPG
| Stock | Sep 24 | May 26 | Return |
|---|---|---|---|
| MBX Biosciences, In… (MBX) | 100 | 133.6 | +33.6% |
| PepGen Inc. (PEPG) | 100 | 20.9 | -79.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MBX vs PEPG
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Bottom line: MBX leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and recent price momentum and sentiment. PepGen Inc. is the stronger pick specifically for growth and revenue expansion and capital preservation and lower volatility. As sector peers, any of these can serve as alternatives in the same allocation.
MBX
MBX Biosciences, Inc. Common Stock
The Long-Run Compounder
MBX carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.
- 46.8% 10Y total return vs PEPG's -86.1%
- Lower volatility, beta 1.33, Low D/E 0.1%, current ratio 24.19x
- 2.3% margin vs PEPG's 2.3%
Best for: long-term compounding and sleep-well-at-night
PEPG
PepGen Inc.
The Income Pick
PEPG is the clearest fit if your priority is income & stability and growth exposure.
- beta 0.17
- EPS growth 25.6%
- Beta 0.17, current ratio 11.94x
Best for: income & stability and growth exposure
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | PEPG | -1.0% revenue growth vs MBX's -46.0% |
| Quality / Margins | MBX | 2.3% margin vs PEPG's 2.3% |
| Stability / Safety | PEPG | Beta 0.17 vs MBX's 1.33 |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | MBX | +220.5% vs PEPG's +42.1% |
| Efficiency (ROA) | MBX | -20.1% ROA vs PEPG's -60.4%, ROIC -96.9% vs -73.2% |
MBX vs PEPG — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
BEST OVERALLMBXLAGGINGPEPG
PEPGPepGen Inc.
1leads
MBXMBX Biosciences, Inc.…
2leads
6 Total Categories
CATEGORYLEADERvs PEPGMETRICS WON
Income & Cash FlowRevenue, margins, and cash flow strength
PEPG1/1
Valuation MetricsMultiples, price ratios, and targets
Tied
—
Profitability & EfficiencyROE, ROIC, leverage, and quality scores
MBX6/7
Total Returns1Y, 3Y, 5Y total returns with dividends
MBX6/6
Risk & VolatilityBeta, volatility, and downside exposure
Tied
—
Analyst OutlookRatings, price targets, and dividends
—
—
Income & Cash Flow (Last 12 Months)
PEPG leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
MBX and PEPG operate at a comparable scale, with $0 and $0 in trailing revenue.
| Metric | MBXMBX Biosciences, … | PEPGPepGen Inc. |
|---|---|---|
| RevenueTrailing 12 months | $0 | $0 |
| EBITDAEarnings before interest/tax | -$91M | -$90M |
| Net IncomeAfter-tax profit | -$80M | -$90M |
| Free Cash FlowCash after capex | -$79M | -$82M |
| Gross MarginGross profit ÷ Revenue | — | — |
| Operating MarginEBIT ÷ Revenue | — | — |
| Net MarginNet income ÷ Revenue | — | — |
| FCF MarginFCF ÷ Revenue | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — |
| EPS Growth (YoY)Latest quarter vs prior year | -16.7% | +60.3% |
PEPG leads this category, winning 1 of 1 comparable metric.
Valuation Metrics
Evenly matched — MBX and PEPG each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | MBXMBX Biosciences, … | PEPGPepGen Inc. |
|---|---|---|
| Market CapShares × price | $1.6B | $123M |
| Enterprise ValueMkt cap + debt − cash | $1.5B | $80M |
| Trailing P/EPrice ÷ TTM EPS | -18.76x | -0.84x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — |
| Price / BookPrice ÷ Book value/share | 4.50x | 0.51x |
| Price / FCFMarket cap ÷ FCF | — | — |
Evenly matched — MBX and PEPG each lead in 1 of 2 comparable metrics.
Profitability & Efficiency
MBX leads this category, winning 6 of 7 comparable metrics.
Profitability & Efficiency
MBX delivers a -20.8% return on equity — every $100 of shareholder capital generates $-21 in annual profit, vs $-76 for PEPG. MBX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to PEPG's 0.12x.
| Metric | MBXMBX Biosciences, … | PEPGPepGen Inc. |
|---|---|---|
| ROE (TTM)Return on equity | -20.8% | -75.7% |
| ROA (TTM)Return on assets | -20.1% | -60.4% |
| ROICReturn on invested capital | -96.9% | -73.2% |
| ROCEReturn on capital employed | -40.4% | -63.4% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.00x | 0.12x |
| Net DebtTotal debt minus cash | -$49M | -$44M |
| Cash & Equiv.Liquid assets | $49M | $61M |
| Total DebtShort + long-term debt | $171,000 | $17M |
| Interest CoverageEBIT ÷ Interest expense | — | — |
MBX leads this category, winning 6 of 7 comparable metrics.
Total Returns (Dividends Reinvested)
MBX leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MBX five years ago would be worth $14,677 today (with dividends reinvested), compared to $1,389 for PEPG. Over the past 12 months, MBX leads with a +220.5% total return vs PEPG's +42.1%. The 3-year compound annual growth rate (CAGR) favors MBX at 13.6% vs PEPG's -50.7% — a key indicator of consistent wealth creation.
| Metric | MBXMBX Biosciences, … | PEPGPepGen Inc. |
|---|---|---|
| YTD ReturnYear-to-date | +13.6% | -75.0% |
| 1-Year ReturnPast 12 months | +220.5% | +42.1% |
| 3-Year ReturnCumulative with dividends | +46.8% | -88.1% |
| 5-Year ReturnCumulative with dividends | +46.8% | -86.1% |
| 10-Year ReturnCumulative with dividends | +46.8% | -86.1% |
| CAGR (3Y)Annualised 3-year return | +13.6% | -50.7% |
MBX leads this category, winning 6 of 6 comparable metrics.
Risk & Volatility
Evenly matched — MBX and PEPG each lead in 1 of 2 comparable metrics.
Risk & Volatility
PEPG is the less volatile stock with a 0.17 beta — it tends to amplify market swings less than MBX's 1.33 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MBX currently trades 77.3% from its 52-week high vs PEPG's 22.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | MBXMBX Biosciences, … | PEPGPepGen Inc. |
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.33x | 0.17x |
| 52-Week HighHighest price in past year | $44.89 | $7.80 |
| 52-Week LowLowest price in past year | $9.43 | $1.01 |
| % of 52W HighCurrent price vs 52-week peak | +77.3% | +22.9% |
| RSI (14)Momentum oscillator 0–100 | 53.7 | 37.6 |
| Avg Volume (50D)Average daily shares traded | 491K | 1.5M |
Evenly matched — MBX and PEPG each lead in 1 of 2 comparable metrics.
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates MBX as "Buy" and PEPG as "Buy". Consensus price targets imply 291.1% upside for PEPG (target: $7) vs 59.4% for MBX (target: $55).
| Metric | MBXMBX Biosciences, … | PEPGPepGen Inc. |
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $55.33 | $7.00 |
| # AnalystsCovering analysts | 4 | 6 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
Insufficient data to determine a leader in this category.
Key Takeaway
MBX leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). PEPG leads in 1 (Income & Cash Flow). 2 tied.
Best OverallMBX Biosciences, Inc. Commo… (MBX)Leads 2 of 6 categories
Loading custom metrics...
MBX vs PEPG: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is MBX or PEPG a better buy right now?
Analysts rate MBX Biosciences, Inc.
Common Stock (MBX) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — MBX or PEPG?
Over the past 5 years, MBX Biosciences, Inc.
Common Stock (MBX) delivered a total return of +46. 8%, compared to -86. 1% for PepGen Inc. (PEPG). Over 10 years, the gap is even starker: MBX returned +46. 8% versus PEPG's -86. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — MBX or PEPG?
By beta (market sensitivity over 5 years), PepGen Inc.
(PEPG) is the lower-risk stock at 0. 17β versus MBX Biosciences, Inc. Common Stock's 1. 33β — meaning MBX is approximately 671% more volatile than PEPG relative to the S&P 500. On balance sheet safety, MBX Biosciences, Inc. Common Stock (MBX) carries a lower debt/equity ratio of 0% versus 12% for PepGen Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — MBX or PEPG?
On earnings-per-share growth, the picture is similar: PepGen Inc.
grew EPS 25. 6% year-over-year, compared to -81. 4% for MBX Biosciences, Inc. Common Stock. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — MBX or PEPG?
MBX Biosciences, Inc.
Common Stock (MBX) is the more profitable company, earning 0. 0% net margin versus 0. 0% for PepGen Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MBX leads at 0. 0% versus 0. 0% for PEPG. At the gross margin level — before operating expenses — MBX leads at 0. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — MBX or PEPG?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is MBX or PEPG better for a retirement portfolio?
For long-horizon retirement investors, PepGen Inc.
(PEPG) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 17)). Both have compounded well over 10 years (PEPG: -86. 1%, MBX: +46. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between MBX and PEPG?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.