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MNKD vs INSM
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
MNKD vs INSM — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $1.10B | $29.14B |
| Revenue (TTM) | $361M | $447M |
| Net Income (TTM) | $-24M | $-1.18B |
| Gross Margin | 79.3% | 70.0% |
| Operating Margin | 4.1% | -272.1% |
| Forward P/E | 218.4x | — |
| Total Debt | $473M | $46M |
| Cash & Equiv. | $75M | $510M |
MNKD vs INSM — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| MannKind Corporation (MNKD) | 100 | 235.8 | +135.8% |
| Insmed Incorporated (INSM) | 100 | 564.4 | +464.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MNKD vs INSM
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MNKD is the clearest fit if your priority is quality and efficiency.
- -6.6% margin vs INSM's -264.8%
- -3.9% ROA vs INSM's -50.1%, ROIC 21.6% vs -141.8%
INSM carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 0.54
- Rev growth 66.7%, EPS growth -15.3%, 3Y rev CAGR 35.2%
- 11.3% 10Y total return vs MNKD's -46.5%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 66.7% revenue growth vs MNKD's 22.2% | |
| Quality / Margins | -6.6% margin vs INSM's -264.8% | |
| Stability / Safety | Beta 0.54 vs MNKD's 0.90 | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +102.0% vs MNKD's -25.5% | |
| Efficiency (ROA) | -3.9% ROA vs INSM's -50.1%, ROIC 21.6% vs -141.8% |
MNKD vs INSM — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
MNKD vs INSM — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
MNKD leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
INSM and MNKD operate at a comparable scale, with $447M and $361M in trailing revenue. Profitability is closely matched — net margins range from -6.6% (MNKD) to -2.6% (INSM). On growth, INSM holds the edge at +52.4% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $361M | $447M |
| EBITDAEarnings before interest/tax | $25M | -$1.2B |
| Net IncomeAfter-tax profit | -$24M | -$1.2B |
| Free Cash FlowCash after capex | $13M | -$906M |
| Gross MarginGross profit ÷ Revenue | +79.3% | +70.0% |
| Operating MarginEBIT ÷ Revenue | +4.1% | -2.7% |
| Net MarginNet income ÷ Revenue | -6.6% | -2.6% |
| FCF MarginFCF ÷ Revenue | +3.6% | -2.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +15.1% | +52.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -2.2% | -37.8% |
Valuation Metrics
Evenly matched — MNKD and INSM each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $1.1B | $29.1B |
| Enterprise ValueMkt cap + debt − cash | $1.5B | $28.7B |
| Trailing P/EPrice ÷ TTM EPS | 178.00x | -21.35x |
| Forward P/EPrice ÷ next-FY EPS est. | 218.40x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | 29.32x | — |
| Price / SalesMarket cap ÷ Revenue | 3.15x | 48.06x |
| Price / BookPrice ÷ Book value/share | — | 36.92x |
| Price / FCFMarket cap ÷ FCF | 80.31x | — |
Profitability & Efficiency
MNKD leads this category, winning 4 of 6 comparable metrics.
Profitability & Efficiency
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | — | -125.2% |
| ROA (TTM)Return on assets | -3.9% | -50.1% |
| ROICReturn on invested capital | +21.6% | -141.8% |
| ROCEReturn on capital employed | +8.3% | -70.8% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 |
| Debt / EquityFinancial leverage | — | 0.06x |
| Net DebtTotal debt minus cash | $399M | -$465M |
| Cash & Equiv.Liquid assets | $75M | $510M |
| Total DebtShort + long-term debt | $473M | $46M |
| Interest CoverageEBIT ÷ Interest expense | 0.75x | -12.98x |
Total Returns (Dividends Reinvested)
INSM leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in INSM five years ago would be worth $42,182 today (with dividends reinvested), compared to $8,725 for MNKD. Over the past 12 months, INSM leads with a +102.0% total return vs MNKD's -25.5%. The 3-year compound annual growth rate (CAGR) favors INSM at 93.6% vs MNKD's -2.8% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | -36.4% | -22.6% |
| 1-Year ReturnPast 12 months | -25.5% | +102.0% |
| 3-Year ReturnCumulative with dividends | -8.2% | +625.3% |
| 5-Year ReturnCumulative with dividends | -12.7% | +321.8% |
| 10-Year ReturnCumulative with dividends | -46.5% | +1133.9% |
| CAGR (3Y)Annualised 3-year return | -2.8% | +93.6% |
Risk & Volatility
INSM leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
INSM is the less volatile stock with a 0.54 beta — it tends to amplify market swings less than MNKD's 0.90 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. INSM currently trades 64.4% from its 52-week high vs MNKD's 54.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.90x | 0.54x |
| 52-Week HighHighest price in past year | $6.51 | $212.75 |
| 52-Week LowLowest price in past year | $2.23 | $63.81 |
| % of 52W HighCurrent price vs 52-week peak | +54.7% | +64.4% |
| RSI (14)Momentum oscillator 0–100 | 53.6 | 44.5 |
| Avg Volume (50D)Average daily shares traded | 6.8M | 2.1M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates MNKD as "Buy" and INSM as "Buy". Consensus price targets imply 96.6% upside for MNKD (target: $7) vs 58.4% for INSM (target: $217).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy |
| Price TargetConsensus 12-month target | $7.00 | $217.11 |
| # AnalystsCovering analysts | 19 | 35 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | — | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
MNKD leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). INSM leads in 2 (Total Returns, Risk & Volatility). 1 tied.
MNKD vs INSM: Frequently Asked Questions
9 questions · data-driven answers · updated daily
01Is MNKD or INSM a better buy right now?
For growth investors, Insmed Incorporated (INSM) is the stronger pick with 66.
7% revenue growth year-over-year, versus 22. 2% for MannKind Corporation (MNKD). MannKind Corporation (MNKD) offers the better valuation at 178. 0x trailing P/E (218. 4x forward), making it the more compelling value choice. Analysts rate MannKind Corporation (MNKD) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — MNKD or INSM?
Over the past 5 years, Insmed Incorporated (INSM) delivered a total return of +321.
8%, compared to -12. 7% for MannKind Corporation (MNKD). Over 10 years, the gap is even starker: INSM returned +1134% versus MNKD's -46. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — MNKD or INSM?
By beta (market sensitivity over 5 years), Insmed Incorporated (INSM) is the lower-risk stock at 0.
54β versus MannKind Corporation's 0. 90β — meaning MNKD is approximately 66% more volatile than INSM relative to the S&P 500.
04Which is growing faster — MNKD or INSM?
By revenue growth (latest reported year), Insmed Incorporated (INSM) is pulling ahead at 66.
7% versus 22. 2% for MannKind Corporation (MNKD). On earnings-per-share growth, the picture is similar: Insmed Incorporated grew EPS -15. 3% year-over-year, compared to -79. 4% for MannKind Corporation. Over a 3-year CAGR, MNKD leads at 51. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — MNKD or INSM?
MannKind Corporation (MNKD) is the more profitable company, earning 1.
7% net margin versus -210. 5% for Insmed Incorporated — meaning it keeps 1. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MNKD leads at 11. 1% versus -205. 6% for INSM. At the gross margin level — before operating expenses — MNKD leads at 82. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is MNKD or INSM more undervalued right now?
Analyst consensus price targets imply the most upside for MNKD: 96.
6% to $7. 00.
07Which pays a better dividend — MNKD or INSM?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is MNKD or INSM better for a retirement portfolio?
For long-horizon retirement investors, Insmed Incorporated (INSM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
54), +1134% 10Y return). Both have compounded well over 10 years (INSM: +1134%, MNKD: -46. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between MNKD and INSM?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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