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Stock Comparison

MNKD vs PTCT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MNKD
MannKind Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.10B
5Y Perf.+135.1%
PTCT
PTC Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.35B
5Y Perf.+27.2%

MNKD vs PTCT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MNKD logoMNKD
PTCT logoPTCT
IndustryBiotechnologyBiotechnology
Market Cap$1.10B$5.35B
Revenue (TTM)$361M$827M
Net Income (TTM)$-24M$-187M
Gross Margin79.3%49.7%
Operating Margin4.1%-8.3%
Forward P/E217.8x8.3x
Total Debt$473M$492M
Cash & Equiv.$75M$985M

MNKD vs PTCTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MNKD
PTCT
StockMay 20May 26Return
MannKind Corporation (MNKD)100235.1+135.1%
PTC Therapeutics, I… (PTCT)100127.2+27.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: MNKD vs PTCT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: MNKD and PTCT are tied at the top with 3 categories each — the right choice depends on your priorities. PTC Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and valuation and capital efficiency. As sector peers, any of these can serve as alternatives in the same allocation.
MNKD
MannKind Corporation
The Income Pick

MNKD has the current edge in this matchup, primarily because of its strength in income & stability and sleep-well-at-night.

  • beta 0.90
  • Lower volatility, beta 0.90, current ratio 1.70x
  • Beta 0.90, current ratio 1.70x
Best for: income & stability and sleep-well-at-night
PTCT
PTC Therapeutics, Inc.
The Growth Play

PTCT is the clearest fit if your priority is growth exposure and long-term compounding.

  • Rev growth 114.5%, EPS growth 264.5%, 3Y rev CAGR 35.3%
  • 7.3% 10Y total return vs MNKD's -46.2%
  • 114.5% revenue growth vs MNKD's 22.2%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthPTCT logoPTCT114.5% revenue growth vs MNKD's 22.2%
ValuePTCT logoPTCTLower P/E (8.3x vs 217.8x)
Quality / MarginsMNKD logoMNKD-6.6% margin vs PTCT's -22.6%
Stability / SafetyMNKD logoMNKDBeta 0.90 vs PTCT's 1.13
DividendsTieNeither stock pays a meaningful dividend
Momentum (1Y)PTCT logoPTCT+58.2% vs MNKD's -26.8%
Efficiency (ROA)MNKD logoMNKD-3.9% ROA vs PTCT's -6.8%

MNKD vs PTCT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MNKDMannKind Corporation
FY 2025
Product Revenue
62.0%$217M
Royalty
36.7%$128M
Service
1.2%$4M
PTCTPTC Therapeutics, Inc.
FY 2025
Collaboration and License Revenue
54.6%$998M
Product
32.1%$587M
Royalty
13.4%$244M

MNKD vs PTCT — Financial Metrics

Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLPTCTLAGGINGMNKD

Income & Cash Flow (Last 12 Months)

MNKD leads this category, winning 5 of 6 comparable metrics.

PTCT is the larger business by revenue, generating $827M annually — 2.3x MNKD's $361M. MNKD is the more profitable business, keeping -6.6% of every revenue dollar as net income compared to PTCT's -22.6%. On growth, MNKD holds the edge at +15.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMNKD logoMNKDMannKind Corporat…PTCT logoPTCTPTC Therapeutics,…
RevenueTrailing 12 months$361M$827M
EBITDAEarnings before interest/tax$25M-$37M
Net IncomeAfter-tax profit-$24M-$187M
Free Cash FlowCash after capex$13M-$229M
Gross MarginGross profit ÷ Revenue+79.3%+49.7%
Operating MarginEBIT ÷ Revenue+4.1%-8.3%
Net MarginNet income ÷ Revenue-6.6%-22.6%
FCF MarginFCF ÷ Revenue+3.6%-27.7%
Rev. Growth (YoY)Latest quarter vs prior year+15.1%-76.8%
EPS Growth (YoY)Latest quarter vs prior year-2.2%-100.3%
MNKD leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

PTCT leads this category, winning 4 of 4 comparable metrics.

At 8.3x trailing earnings, PTCT trades at a 95% valuation discount to MNKD's 177.5x P/E. On an enterprise value basis, PTCT's 5.4x EV/EBITDA is more attractive than MNKD's 29.3x.

MetricMNKD logoMNKDMannKind Corporat…PTCT logoPTCTPTC Therapeutics,…
Market CapShares × price$1.1B$5.3B
Enterprise ValueMkt cap + debt − cash$1.5B$4.9B
Trailing P/EPrice ÷ TTM EPS177.50x8.29x
Forward P/EPrice ÷ next-FY EPS est.217.79x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple29.26x5.42x
Price / SalesMarket cap ÷ Revenue3.14x3.09x
Price / BookPrice ÷ Book value/share
Price / FCFMarket cap ÷ FCF80.08x7.61x
PTCT leads this category, winning 4 of 4 comparable metrics.

Profitability & Efficiency

Evenly matched — MNKD and PTCT each lead in 3 of 6 comparable metrics.

On the Piotroski fundamental quality scale (0–9), PTCT scores 7/9 vs MNKD's 4/9, reflecting strong financial health.

MetricMNKD logoMNKDMannKind Corporat…PTCT logoPTCTPTC Therapeutics,…
ROE (TTM)Return on equity
ROA (TTM)Return on assets-3.9%-6.8%
ROICReturn on invested capital+21.6%
ROCEReturn on capital employed+8.3%+55.9%
Piotroski ScoreFundamental quality 0–947
Debt / EquityFinancial leverage
Net DebtTotal debt minus cash$399M-$492M
Cash & Equiv.Liquid assets$75M$985M
Total DebtShort + long-term debt$473M$492M
Interest CoverageEBIT ÷ Interest expense0.75x-1.67x
Evenly matched — MNKD and PTCT each lead in 3 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

PTCT leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in PTCT five years ago would be worth $16,026 today (with dividends reinvested), compared to $8,275 for MNKD. Over the past 12 months, PTCT leads with a +58.2% total return vs MNKD's -26.8%. The 3-year compound annual growth rate (CAGR) favors PTCT at 5.1% vs MNKD's -2.9% — a key indicator of consistent wealth creation.

MetricMNKD logoMNKDMannKind Corporat…PTCT logoPTCTPTC Therapeutics,…
YTD ReturnYear-to-date-36.6%-16.0%
1-Year ReturnPast 12 months-26.8%+58.2%
3-Year ReturnCumulative with dividends-8.5%+16.1%
5-Year ReturnCumulative with dividends-17.2%+60.3%
10-Year ReturnCumulative with dividends-46.2%+733.2%
CAGR (3Y)Annualised 3-year return-2.9%+5.1%
PTCT leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — MNKD and PTCT each lead in 1 of 2 comparable metrics.

MNKD is the less volatile stock with a 0.90 beta — it tends to amplify market swings less than PTCT's 1.13 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PTCT currently trades 73.7% from its 52-week high vs MNKD's 54.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMNKD logoMNKDMannKind Corporat…PTCT logoPTCTPTC Therapeutics,…
Beta (5Y)Sensitivity to S&P 5000.90x1.13x
52-Week HighHighest price in past year$6.51$87.50
52-Week LowLowest price in past year$2.23$37.94
% of 52W HighCurrent price vs 52-week peak+54.5%+73.7%
RSI (14)Momentum oscillator 0–10074.345.3
Avg Volume (50D)Average daily shares traded6.4M1.0M
Evenly matched — MNKD and PTCT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Wall Street rates MNKD as "Buy" and PTCT as "Buy". Consensus price targets imply 97.2% upside for MNKD (target: $7) vs 39.0% for PTCT (target: $90).

MetricMNKD logoMNKDMannKind Corporat…PTCT logoPTCTPTC Therapeutics,…
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$7.00$89.67
# AnalystsCovering analysts1926
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

PTCT leads in 2 of 6 categories (Valuation Metrics, Total Returns). MNKD leads in 1 (Income & Cash Flow). 2 tied.

Best OverallPTC Therapeutics, Inc. (PTCT)Leads 2 of 6 categories
Loading custom metrics...

MNKD vs PTCT: Frequently Asked Questions

10 questions · data-driven answers · updated daily

01

Is MNKD or PTCT a better buy right now?

For growth investors, PTC Therapeutics, Inc.

(PTCT) is the stronger pick with 114. 5% revenue growth year-over-year, versus 22. 2% for MannKind Corporation (MNKD). PTC Therapeutics, Inc. (PTCT) offers the better valuation at 8. 3x trailing P/E, making it the more compelling value choice. Analysts rate MannKind Corporation (MNKD) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MNKD or PTCT?

On trailing P/E, PTC Therapeutics, Inc.

(PTCT) is the cheapest at 8. 3x versus MannKind Corporation at 177. 5x.

03

Which is the better long-term investment — MNKD or PTCT?

Over the past 5 years, PTC Therapeutics, Inc.

(PTCT) delivered a total return of +60. 3%, compared to -17. 2% for MannKind Corporation (MNKD). Over 10 years, the gap is even starker: PTCT returned +733. 2% versus MNKD's -46. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MNKD or PTCT?

By beta (market sensitivity over 5 years), MannKind Corporation (MNKD) is the lower-risk stock at 0.

90β versus PTC Therapeutics, Inc. 's 1. 13β — meaning PTCT is approximately 26% more volatile than MNKD relative to the S&P 500.

05

Which is growing faster — MNKD or PTCT?

By revenue growth (latest reported year), PTC Therapeutics, Inc.

(PTCT) is pulling ahead at 114. 5% versus 22. 2% for MannKind Corporation (MNKD). On earnings-per-share growth, the picture is similar: PTC Therapeutics, Inc. grew EPS 264. 5% year-over-year, compared to -79. 4% for MannKind Corporation. Over a 3-year CAGR, MNKD leads at 51. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MNKD or PTCT?

PTC Therapeutics, Inc.

(PTCT) is the more profitable company, earning 39. 4% net margin versus 1. 7% for MannKind Corporation — meaning it keeps 39. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PTCT leads at 49. 5% versus 11. 1% for MNKD. At the gross margin level — before operating expenses — PTCT leads at 95. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MNKD or PTCT more undervalued right now?

Analyst consensus price targets imply the most upside for MNKD: 97.

2% to $7. 00.

08

Which pays a better dividend — MNKD or PTCT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is MNKD or PTCT better for a retirement portfolio?

For long-horizon retirement investors, PTC Therapeutics, Inc.

(PTCT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 13), +733. 2% 10Y return). Both have compounded well over 10 years (PTCT: +733. 2%, MNKD: -46. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MNKD and PTCT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.

Stocks Like

MNKD

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 7%
  • Gross Margin > 47%
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PTCT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 29%
Run This Screen
Custom Screen

Beat Both

Find stocks that outperform MNKD and PTCT on the metrics below

Revenue Growth>
%
(MNKD: 15.1% · PTCT: -76.8%)
P/E Ratio<
x
(MNKD: 177.5x · PTCT: 8.3x)

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