Biotechnology
Compare Stocks
2 / 10Stock Comparison
MRNA vs CVAC
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
MRNA vs CVAC — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||
|---|---|---|
| Industry | Biotechnology | Biotechnology |
| Market Cap | $19.35B | $1.05B |
| Revenue (TTM) | $2.23B | $511M |
| Net Income (TTM) | $-3.19B | $194M |
| Gross Margin | -13.9% | 94.8% |
| Operating Margin | -153.3% | 40.8% |
| Forward P/E | — | 6.5x |
| Total Debt | $1.92B | $39M |
| Cash & Equiv. | $2.60B | $482M |
MRNA vs CVAC — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Aug 20 | May 26 | Return |
|---|---|---|---|
| Moderna, Inc. (MRNA) | 100 | 75.2 | -24.8% |
| CureVac N.V. (CVAC) | 100 | 8.2 | -91.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MRNA vs CVAC
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MRNA is the clearest fit if your priority is long-term compounding.
- 162.3% 10Y total return vs CVAC's -91.7%
- +99.7% vs CVAC's +38.7%
CVAC carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- beta 1.23
- Rev growth 9.0%, EPS growth 161.0%, 3Y rev CAGR 73.2%
- Lower volatility, beta 1.23, Low D/E 5.6%, current ratio 7.28x
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 9.0% revenue growth vs MRNA's -39.2% | |
| Quality / Margins | 37.9% margin vs MRNA's -143.6% | |
| Stability / Safety | Beta 1.23 vs MRNA's 1.82, lower leverage | |
| Dividends | Tie | Neither stock pays a meaningful dividend |
| Momentum (1Y) | +99.7% vs CVAC's +38.7% | |
| Efficiency (ROA) | 28.1% ROA vs MRNA's -26.6%, ROIC 65.0% vs -26.1% |
MRNA vs CVAC — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
MRNA vs CVAC — Financial Metrics
Side-by-side numbers across 2 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
CVAC leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MRNA is the larger business by revenue, generating $2.2B annually — 4.4x CVAC's $511M. CVAC is the more profitable business, keeping 37.9% of every revenue dollar as net income compared to MRNA's -143.6%. On growth, MRNA holds the edge at +2.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||
|---|---|---|
| RevenueTrailing 12 months | $2.2B | $511M |
| EBITDAEarnings before interest/tax | -$3.2B | $226M |
| Net IncomeAfter-tax profit | -$3.2B | $194M |
| Free Cash FlowCash after capex | -$1.6B | $196M |
| Gross MarginGross profit ÷ Revenue | -13.9% | +94.8% |
| Operating MarginEBIT ÷ Revenue | -153.3% | +40.8% |
| Net MarginNet income ÷ Revenue | -143.6% | +37.9% |
| FCF MarginFCF ÷ Revenue | -71.1% | +38.4% |
| Rev. Growth (YoY)Latest quarter vs prior year | +2.6% | -91.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -34.9% | +18.8% |
Valuation Metrics
CVAC leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | ||
|---|---|---|
| Market CapShares × price | $19.3B | $1.0B |
| Enterprise ValueMkt cap + debt − cash | $18.7B | $607M |
| Trailing P/EPrice ÷ TTM EPS | -6.72x | 6.47x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — |
| EV / EBITDAEnterprise value multiple | — | 3.09x |
| Price / SalesMarket cap ÷ Revenue | 9.95x | 1.96x |
| Price / BookPrice ÷ Book value/share | 2.19x | 1.51x |
| Price / FCFMarket cap ÷ FCF | — | 12.58x |
Profitability & Efficiency
CVAC leads this category, winning 8 of 9 comparable metrics.
Profitability & Efficiency
CVAC delivers a 33.0% return on equity — every $100 of shareholder capital generates $33 in annual profit, vs $-37 for MRNA. CVAC carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRNA's 0.22x. On the Piotroski fundamental quality scale (0–9), CVAC scores 7/9 vs MRNA's 3/9, reflecting strong financial health.
| Metric | ||
|---|---|---|
| ROE (TTM)Return on equity | -36.7% | +33.0% |
| ROA (TTM)Return on assets | -26.6% | +28.1% |
| ROICReturn on invested capital | -26.1% | +65.0% |
| ROCEReturn on capital employed | -27.6% | +26.7% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 7 |
| Debt / EquityFinancial leverage | 0.22x | 0.06x |
| Net DebtTotal debt minus cash | -$679M | -$443M |
| Cash & Equiv.Liquid assets | $2.6B | $482M |
| Total DebtShort + long-term debt | $1.9B | $39M |
| Interest CoverageEBIT ÷ Interest expense | -1803.00x | 547.87x |
Total Returns (Dividends Reinvested)
MRNA leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MRNA five years ago would be worth $3,040 today (with dividends reinvested), compared to $496 for CVAC. Over the past 12 months, MRNA leads with a +99.7% total return vs CVAC's +38.7%. The 3-year compound annual growth rate (CAGR) favors CVAC at -18.0% vs MRNA's -28.2% — a key indicator of consistent wealth creation.
| Metric | ||
|---|---|---|
| YTD ReturnYear-to-date | +58.1% | -0.2% |
| 1-Year ReturnPast 12 months | +99.7% | +38.7% |
| 3-Year ReturnCumulative with dividends | -63.0% | -44.9% |
| 5-Year ReturnCumulative with dividends | -69.6% | -95.0% |
| 10-Year ReturnCumulative with dividends | +162.3% | -91.7% |
| CAGR (3Y)Annualised 3-year return | -28.2% | -18.0% |
Risk & Volatility
Evenly matched — MRNA and CVAC each lead in 1 of 2 comparable metrics.
Risk & Volatility
CVAC is the less volatile stock with a 1.23 beta — it tends to amplify market swings less than MRNA's 1.82 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.
| Metric | ||
|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.82x | 1.23x |
| 52-Week HighHighest price in past year | $59.55 | $5.72 |
| 52-Week LowLowest price in past year | $22.28 | $3.26 |
| % of 52W HighCurrent price vs 52-week peak | +81.9% | +81.5% |
| RSI (14)Momentum oscillator 0–100 | 40.2 | 47.8 |
| Avg Volume (50D)Average daily shares traded | 6.9M | 0 |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Wall Street rates MRNA as "Hold" and CVAC as "Hold". Consensus price targets imply 350.6% upside for CVAC (target: $21) vs -26.2% for MRNA (target: $36).
| Metric | ||
|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Hold |
| Price TargetConsensus 12-month target | $36.00 | $21.00 |
| # AnalystsCovering analysts | 27 | 8 |
| Dividend YieldAnnual dividend ÷ price | — | — |
| Dividend StreakConsecutive years of raises | 0 | — |
| Dividend / ShareAnnual DPS | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% |
CVAC leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). MRNA leads in 1 (Total Returns). 1 tied.
MRNA vs CVAC: Frequently Asked Questions
8 questions · data-driven answers · updated daily
01Is MRNA or CVAC a better buy right now?
For growth investors, CureVac N.
V. (CVAC) is the stronger pick with 895. 5% revenue growth year-over-year, versus -39. 2% for Moderna, Inc. (MRNA). CureVac N. V. (CVAC) offers the better valuation at 6. 5x trailing P/E, making it the more compelling value choice. Analysts rate Moderna, Inc. (MRNA) a "Hold" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — MRNA or CVAC?
Over the past 5 years, Moderna, Inc.
(MRNA) delivered a total return of -69. 6%, compared to -95. 0% for CureVac N. V. (CVAC). Over 10 years, the gap is even starker: MRNA returned +162. 3% versus CVAC's -91. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — MRNA or CVAC?
By beta (market sensitivity over 5 years), CureVac N.
V. (CVAC) is the lower-risk stock at 1. 23β versus Moderna, Inc. 's 1. 82β — meaning MRNA is approximately 47% more volatile than CVAC relative to the S&P 500. On balance sheet safety, CureVac N. V. (CVAC) carries a lower debt/equity ratio of 6% versus 22% for Moderna, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — MRNA or CVAC?
By revenue growth (latest reported year), CureVac N.
V. (CVAC) is pulling ahead at 895. 5% versus -39. 2% for Moderna, Inc. (MRNA). On earnings-per-share growth, the picture is similar: CureVac N. V. grew EPS 161. 0% year-over-year, compared to 21. 7% for Moderna, Inc.. Over a 3-year CAGR, CVAC leads at 73. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — MRNA or CVAC?
CureVac N.
V. (CVAC) is the more profitable company, earning 30. 3% net margin versus -145. 2% for Moderna, Inc. — meaning it keeps 30. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CVAC leads at 33. 2% versus -158. 1% for MRNA. At the gross margin level — before operating expenses — CVAC leads at 80. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — MRNA or CVAC?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is MRNA or CVAC better for a retirement portfolio?
For long-horizon retirement investors, CureVac N.
V. (CVAC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 23)). Moderna, Inc. (MRNA) carries a higher beta of 1. 82 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CVAC: -91. 7%, MRNA: +162. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between MRNA and CVAC?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MRNA is a mid-cap quality compounder stock; CVAC is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform both.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.