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MYGN vs TMO vs A vs BIO vs ILMN

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MYGN
Myriad Genetics, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$401M
5Y Perf.-70.5%
TMO
Thermo Fisher Scientific Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$172.80B
5Y Perf.+33.2%
A
Agilent Technologies, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$32.73B
5Y Perf.+31.2%
BIO
Bio-Rad Laboratories, Inc.

Medical - Devices

HealthcareNYSE • US
Market Cap$6.87B
5Y Perf.-48.2%
ILMN
Illumina, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$21.55B
5Y Perf.-59.8%

MYGN vs TMO vs A vs BIO vs ILMN — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MYGN logoMYGN
TMO logoTMO
A logoA
BIO logoBIO
ILMN logoILMN
IndustryMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - DevicesMedical - Diagnostics & Research
Market Cap$401M$172.80B$32.73B$6.87B$21.55B
Revenue (TTM)$829M$45.20B$7.07B$2.59B$4.39B
Net Income (TTM)$-400M$6.86B$1.29B$169M$853M
Gross Margin70.0%39.4%38.8%51.9%67.1%
Operating Margin-46.3%17.8%20.6%9.2%20.9%
Forward P/E69.4x18.7x19.4x27.4x27.2x
Total Debt$210M$40.85B$3.35B$1.53B$2.55B
Cash & Equiv.$150M$9.86B$1.79B$532M$1.42B

MYGN vs TMO vs A vs BIO vs ILMNLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MYGN
TMO
A
BIO
ILMN
StockMay 20May 26Return
Myriad Genetics, In… (MYGN)10029.5-70.5%
Thermo Fisher Scien… (TMO)100133.2+33.2%
Agilent Technologie… (A)100131.2+31.2%
Bio-Rad Laboratorie… (BIO)10051.8-48.2%
Illumina, Inc. (ILMN)10040.2-59.8%

Price return only. Dividends and distributions are not included.

Quick Verdict: MYGN vs TMO vs A vs BIO vs ILMN

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ILMN leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and recent price momentum and sentiment. Agilent Technologies, Inc. is the stronger pick specifically for growth and revenue expansion and dividend income and shareholder returns. TMO and BIO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
MYGN
Myriad Genetics, Inc.
The Healthcare Pick

Among these 5 stocks, MYGN doesn't own a clear edge in any measured category.

Best for: healthcare exposure
TMO
Thermo Fisher Scientific Inc.
The Long-Run Compounder

TMO ranks third and is worth considering specifically for long-term compounding.

  • 222.6% 10Y total return vs A's 198.4%
  • Lower P/E (18.7x vs 27.2x)
Best for: long-term compounding
A
Agilent Technologies, Inc.
The Income Pick

A is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.

  • Dividend streak 10 yrs, beta 1.21, yield 0.9%
  • Rev growth 6.7%, EPS growth 3.2%, 3Y rev CAGR 0.5%
  • PEG 1.32 vs TMO's 8.86
  • 6.7% revenue growth vs MYGN's -1.6%
Best for: income & stability and growth exposure
BIO
Bio-Rad Laboratories, Inc.
The Defensive Pick

BIO is the clearest fit if your priority is sleep-well-at-night and defensive.

  • Lower volatility, beta 0.91, Low D/E 20.5%, current ratio 5.62x
  • Beta 0.91, current ratio 5.62x
  • Beta 0.91 vs MYGN's 1.81, lower leverage
Best for: sleep-well-at-night and defensive
ILMN
Illumina, Inc.
The Quality Compounder

ILMN carries the broadest edge in this set and is the clearest fit for quality and momentum.

  • 19.4% margin vs MYGN's -48.2%
  • +78.3% vs BIO's +5.5%
  • 13.4% ROA vs MYGN's -57.4%, ROIC 16.8% vs -8.7%
Best for: quality and momentum
See the full category breakdown
CategoryWinnerWhy
GrowthA logoA6.7% revenue growth vs MYGN's -1.6%
ValueTMO logoTMOLower P/E (18.7x vs 27.2x)
Quality / MarginsILMN logoILMN19.4% margin vs MYGN's -48.2%
Stability / SafetyBIO logoBIOBeta 0.91 vs MYGN's 1.81, lower leverage
DividendsA logoA0.9% yield, 10-year raise streak, vs TMO's 0.4%, (3 stocks pay no dividend)
Momentum (1Y)ILMN logoILMN+78.3% vs BIO's +5.5%
Efficiency (ROA)ILMN logoILMN13.4% ROA vs MYGN's -57.4%, ROIC 16.8% vs -8.7%

MYGN vs TMO vs A vs BIO vs ILMN — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MYGNMyriad Genetics, Inc.
FY 2023
Testing Revenue
100.0%$753M
TMOThermo Fisher Scientific Inc.
FY 2025
Consumables
41.9%$18.7B
Service
41.7%$18.6B
Instruments
16.4%$7.3B
AAgilent Technologies, Inc.
FY 2025
Agilent CrossLab
41.9%$2.9B
Life Sciences and Applied Markets
39.2%$2.7B
Applied Markets
18.9%$1.3B
BIOBio-Rad Laboratories, Inc.
FY 2025
Clinical Diagnostics
60.5%$1.6B
Life Science
39.5%$1.0B
ILMNIllumina, Inc.
FY 2025
Sequencing
91.8%$4.0B
Microarray
8.2%$358M

MYGN vs TMO vs A vs BIO vs ILMN — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLILMNLAGGINGTMO

Income & Cash Flow (Last 12 Months)

ILMN leads this category, winning 3 of 6 comparable metrics.

TMO is the larger business by revenue, generating $45.2B annually — 54.5x MYGN's $829M. ILMN is the more profitable business, keeping 19.4% of every revenue dollar as net income compared to MYGN's -48.2%. On growth, A holds the edge at +7.0% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMYGN logoMYGNMyriad Genetics, …TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…BIO logoBIOBio-Rad Laborator…ILMN logoILMNIllumina, Inc.
RevenueTrailing 12 months$829M$45.2B$7.1B$2.6B$4.4B
EBITDAEarnings before interest/tax-$344M$10.5B$1.7B-$315M$1.1B
Net IncomeAfter-tax profit-$400M$6.9B$1.3B$169M$853M
Free Cash FlowCash after capex-$21M$6.7B$993M$357M$989M
Gross MarginGross profit ÷ Revenue+70.0%+39.4%+38.8%+51.9%+67.1%
Operating MarginEBIT ÷ Revenue-46.3%+17.8%+20.6%+9.2%+20.9%
Net MarginNet income ÷ Revenue-48.2%+15.2%+18.3%+6.5%+19.4%
FCF MarginFCF ÷ Revenue-2.5%+14.9%+14.1%+13.8%+22.5%
Rev. Growth (YoY)Latest quarter vs prior year+2.3%+6.2%+7.0%+1.1%+4.8%
EPS Growth (YoY)Latest quarter vs prior year+11.3%-3.6%-9.5%+6.1%
ILMN leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

BIO leads this category, winning 3 of 7 comparable metrics.

At 9.1x trailing earnings, BIO trades at a 65% valuation discount to TMO's 26.2x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.72x vs TMO's 12.41x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMYGN logoMYGNMyriad Genetics, …TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…BIO logoBIOBio-Rad Laborator…ILMN logoILMNIllumina, Inc.
Market CapShares × price$401M$172.8B$32.7B$6.9B$21.6B
Enterprise ValueMkt cap + debt − cash$461M$203.8B$34.3B$7.9B$22.7B
Trailing P/EPrice ÷ TTM EPS-1.08x26.21x25.30x9.13x26.03x
Forward P/EPrice ÷ next-FY EPS est.69.42x18.71x19.36x27.40x27.22x
PEG RatioP/E ÷ EPS growth rate12.41x1.72x6.15x
EV / EBITDAEnterprise value multiple18.72x19.41x16.53x20.01x
Price / SalesMarket cap ÷ Revenue0.49x3.88x4.71x2.66x4.97x
Price / BookPrice ÷ Book value/share1.09x3.27x4.87x0.93x8.13x
Price / FCFMarket cap ÷ FCF27.46x28.41x18.33x23.15x
BIO leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

ILMN leads this category, winning 5 of 9 comparable metrics.

ILMN delivers a 32.8% return on equity — every $100 of shareholder capital generates $33 in annual profit, vs $-109 for MYGN. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to ILMN's 0.94x. On the Piotroski fundamental quality scale (0–9), ILMN scores 8/9 vs BIO's 5/9, reflecting strong financial health.

MetricMYGN logoMYGNMyriad Genetics, …TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…BIO logoBIOBio-Rad Laborator…ILMN logoILMNIllumina, Inc.
ROE (TTM)Return on equity-109.1%+13.2%+18.7%+2.4%+32.8%
ROA (TTM)Return on assets-57.4%+6.4%+10.1%+2.2%+13.4%
ROICReturn on invested capital-8.7%+7.5%+13.5%+2.6%+16.8%
ROCEReturn on capital employed-9.4%+9.1%+14.5%+2.9%+17.6%
Piotroski ScoreFundamental quality 0–956558
Debt / EquityFinancial leverage0.57x0.76x0.50x0.21x0.94x
Net DebtTotal debt minus cash$60M$31.0B$1.6B$999M$1.1B
Cash & Equiv.Liquid assets$150M$9.9B$1.8B$532M$1.4B
Total DebtShort + long-term debt$210M$40.9B$3.4B$1.5B$2.6B
Interest CoverageEBIT ÷ Interest expense-63.57x5.89x19.53x-2.49x12.09x
ILMN leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — TMO and A and ILMN each lead in 2 of 6 comparable metrics.

A $10,000 investment in TMO five years ago would be worth $10,187 today (with dividends reinvested), compared to $1,643 for MYGN. Over the past 12 months, ILMN leads with a +78.3% total return vs BIO's +5.5%. The 3-year compound annual growth rate (CAGR) favors A at -3.6% vs MYGN's -38.4% — a key indicator of consistent wealth creation.

MetricMYGN logoMYGNMyriad Genetics, …TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…BIO logoBIOBio-Rad Laborator…ILMN logoILMNIllumina, Inc.
YTD ReturnYear-to-date-30.1%-21.4%-15.8%-16.7%+5.6%
1-Year ReturnPast 12 months+6.5%+13.6%+7.3%+5.5%+78.3%
3-Year ReturnCumulative with dividends-76.6%-13.4%-10.5%-32.8%-25.4%
5-Year ReturnCumulative with dividends-83.6%+1.9%-8.9%-57.9%-61.6%
10-Year ReturnCumulative with dividends-87.9%+222.6%+198.4%+79.3%+3.0%
CAGR (3Y)Annualised 3-year return-38.4%-4.7%-3.6%-12.4%-9.3%
Evenly matched — TMO and A and ILMN each lead in 2 of 6 comparable metrics.

Risk & Volatility

Evenly matched — BIO and ILMN each lead in 1 of 2 comparable metrics.

BIO is the less volatile stock with a 0.91 beta — it tends to amplify market swings less than MYGN's 1.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ILMN currently trades 91.2% from its 52-week high vs MYGN's 49.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMYGN logoMYGNMyriad Genetics, …TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…BIO logoBIOBio-Rad Laborator…ILMN logoILMNIllumina, Inc.
Beta (5Y)Sensitivity to S&P 5001.81x1.07x1.21x0.91x1.20x
52-Week HighHighest price in past year$8.59$643.99$160.27$343.12$155.53
52-Week LowLowest price in past year$3.75$385.46$106.55$211.43$75.24
% of 52W HighCurrent price vs 52-week peak+49.9%+72.2%+72.1%+74.1%+91.2%
RSI (14)Momentum oscillator 0–10035.243.954.136.159.5
Avg Volume (50D)Average daily shares traded1.8M1.9M1.9M304K1.5M
Evenly matched — BIO and ILMN each lead in 1 of 2 comparable metrics.

Analyst Outlook

A leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: MYGN as "Hold", TMO as "Buy", A as "Buy", BIO as "Buy", ILMN as "Buy". Consensus price targets imply 43.6% upside for A (target: $166) vs 3.9% for ILMN (target: $147). For income investors, A offers the higher dividend yield at 0.86% vs TMO's 0.36%.

MetricMYGN logoMYGNMyriad Genetics, …TMO logoTMOThermo Fisher Sci…A logoAAgilent Technolog…BIO logoBIOBio-Rad Laborator…ILMN logoILMNIllumina, Inc.
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuyBuy
Price TargetConsensus 12-month target$6.00$654.67$166.00$312.50$147.38
# AnalystsCovering analysts3642381450
Dividend YieldAnnual dividend ÷ price+0.4%+0.9%
Dividend StreakConsecutive years of raises810
Dividend / ShareAnnual DPS$1.69$0.99
Buyback YieldShare repurchases ÷ mkt cap0.0%+1.7%+1.3%+4.3%+3.4%
A leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ILMN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BIO leads in 1 (Valuation Metrics). 2 tied.

Best OverallIllumina, Inc. (ILMN)Leads 2 of 6 categories
Loading custom metrics...

MYGN vs TMO vs A vs BIO vs ILMN: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MYGN or TMO or A or BIO or ILMN a better buy right now?

For growth investors, Agilent Technologies, Inc.

(A) is the stronger pick with 6. 7% revenue growth year-over-year, versus -1. 6% for Myriad Genetics, Inc. (MYGN). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 1x trailing P/E (27. 4x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MYGN or TMO or A or BIO or ILMN?

On trailing P/E, Bio-Rad Laboratories, Inc.

(BIO) is the cheapest at 9. 1x versus Thermo Fisher Scientific Inc. at 26. 2x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 18. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 32x versus Thermo Fisher Scientific Inc. 's 8. 86x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — MYGN or TMO or A or BIO or ILMN?

Over the past 5 years, Thermo Fisher Scientific Inc.

(TMO) delivered a total return of +1. 9%, compared to -83. 6% for Myriad Genetics, Inc. (MYGN). Over 10 years, the gap is even starker: TMO returned +222. 6% versus MYGN's -87. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MYGN or TMO or A or BIO or ILMN?

By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.

(BIO) is the lower-risk stock at 0. 91β versus Myriad Genetics, Inc. 's 1. 81β — meaning MYGN is approximately 99% more volatile than BIO relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 94% for Illumina, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — MYGN or TMO or A or BIO or ILMN?

By revenue growth (latest reported year), Agilent Technologies, Inc.

(A) is pulling ahead at 6. 7% versus -1. 6% for Myriad Genetics, Inc. (MYGN). On earnings-per-share growth, the picture is similar: Illumina, Inc. grew EPS 170. 9% year-over-year, compared to -180. 9% for Myriad Genetics, Inc.. Over a 3-year CAGR, MYGN leads at 6. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MYGN or TMO or A or BIO or ILMN?

Bio-Rad Laboratories, Inc.

(BIO) is the more profitable company, earning 29. 4% net margin versus -44. 4% for Myriad Genetics, Inc. — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: A leads at 21. 3% versus -8. 2% for MYGN. At the gross margin level — before operating expenses — MYGN leads at 69. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MYGN or TMO or A or BIO or ILMN more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 32x versus Thermo Fisher Scientific Inc. 's 8. 86x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 18. 7x forward P/E versus 69. 4x for Myriad Genetics, Inc. — 50. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for A: 43. 6% to $166. 00.

08

Which pays a better dividend — MYGN or TMO or A or BIO or ILMN?

In this comparison, A (0.

9% yield), TMO (0. 4% yield) pay a dividend. MYGN, BIO, ILMN do not pay a meaningful dividend and should not be held primarily for income.

09

Is MYGN or TMO or A or BIO or ILMN better for a retirement portfolio?

For long-horizon retirement investors, Agilent Technologies, Inc.

(A) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 21), 0. 9% yield, +198. 4% 10Y return). Myriad Genetics, Inc. (MYGN) carries a higher beta of 1. 81 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (A: +198. 4%, MYGN: -87. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MYGN and TMO and A and BIO and ILMN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: MYGN is a small-cap quality compounder stock; TMO is a mid-cap quality compounder stock; A is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock; ILMN is a mid-cap quality compounder stock. A pays a dividend while MYGN, TMO, BIO, ILMN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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