Medical - Diagnostics & Research
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5 / 10Stock Comparison
MYGN vs TMO vs A vs BIO vs ILMN
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Diagnostics & Research
Medical - Diagnostics & Research
Medical - Devices
Medical - Diagnostics & Research
MYGN vs TMO vs A vs BIO vs ILMN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Diagnostics & Research | Medical - Diagnostics & Research | Medical - Diagnostics & Research | Medical - Devices | Medical - Diagnostics & Research |
| Market Cap | $401M | $172.80B | $32.73B | $6.87B | $21.55B |
| Revenue (TTM) | $829M | $45.20B | $7.07B | $2.59B | $4.39B |
| Net Income (TTM) | $-400M | $6.86B | $1.29B | $169M | $853M |
| Gross Margin | 70.0% | 39.4% | 38.8% | 51.9% | 67.1% |
| Operating Margin | -46.3% | 17.8% | 20.6% | 9.2% | 20.9% |
| Forward P/E | 69.4x | 18.7x | 19.4x | 27.4x | 27.2x |
| Total Debt | $210M | $40.85B | $3.35B | $1.53B | $2.55B |
| Cash & Equiv. | $150M | $9.86B | $1.79B | $532M | $1.42B |
MYGN vs TMO vs A vs BIO vs ILMN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Myriad Genetics, In… (MYGN) | 100 | 29.5 | -70.5% |
| Thermo Fisher Scien… (TMO) | 100 | 133.2 | +33.2% |
| Agilent Technologie… (A) | 100 | 131.2 | +31.2% |
| Bio-Rad Laboratorie… (BIO) | 100 | 51.8 | -48.2% |
| Illumina, Inc. (ILMN) | 100 | 40.2 | -59.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MYGN vs TMO vs A vs BIO vs ILMN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Among these 5 stocks, MYGN doesn't own a clear edge in any measured category.
TMO ranks third and is worth considering specifically for long-term compounding.
- 222.6% 10Y total return vs A's 198.4%
- Lower P/E (18.7x vs 27.2x)
A is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.
- Dividend streak 10 yrs, beta 1.21, yield 0.9%
- Rev growth 6.7%, EPS growth 3.2%, 3Y rev CAGR 0.5%
- PEG 1.32 vs TMO's 8.86
- 6.7% revenue growth vs MYGN's -1.6%
BIO is the clearest fit if your priority is sleep-well-at-night and defensive.
- Lower volatility, beta 0.91, Low D/E 20.5%, current ratio 5.62x
- Beta 0.91, current ratio 5.62x
- Beta 0.91 vs MYGN's 1.81, lower leverage
ILMN carries the broadest edge in this set and is the clearest fit for quality and momentum.
- 19.4% margin vs MYGN's -48.2%
- +78.3% vs BIO's +5.5%
- 13.4% ROA vs MYGN's -57.4%, ROIC 16.8% vs -8.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 6.7% revenue growth vs MYGN's -1.6% | |
| Value | Lower P/E (18.7x vs 27.2x) | |
| Quality / Margins | 19.4% margin vs MYGN's -48.2% | |
| Stability / Safety | Beta 0.91 vs MYGN's 1.81, lower leverage | |
| Dividends | 0.9% yield, 10-year raise streak, vs TMO's 0.4%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +78.3% vs BIO's +5.5% | |
| Efficiency (ROA) | 13.4% ROA vs MYGN's -57.4%, ROIC 16.8% vs -8.7% |
MYGN vs TMO vs A vs BIO vs ILMN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
MYGN vs TMO vs A vs BIO vs ILMN — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ILMN leads in 2 of 6 categories
BIO leads 1 • A leads 1 • MYGN leads 0 • TMO leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ILMN leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
TMO is the larger business by revenue, generating $45.2B annually — 54.5x MYGN's $829M. ILMN is the more profitable business, keeping 19.4% of every revenue dollar as net income compared to MYGN's -48.2%. On growth, A holds the edge at +7.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $829M | $45.2B | $7.1B | $2.6B | $4.4B |
| EBITDAEarnings before interest/tax | -$344M | $10.5B | $1.7B | -$315M | $1.1B |
| Net IncomeAfter-tax profit | -$400M | $6.9B | $1.3B | $169M | $853M |
| Free Cash FlowCash after capex | -$21M | $6.7B | $993M | $357M | $989M |
| Gross MarginGross profit ÷ Revenue | +70.0% | +39.4% | +38.8% | +51.9% | +67.1% |
| Operating MarginEBIT ÷ Revenue | -46.3% | +17.8% | +20.6% | +9.2% | +20.9% |
| Net MarginNet income ÷ Revenue | -48.2% | +15.2% | +18.3% | +6.5% | +19.4% |
| FCF MarginFCF ÷ Revenue | -2.5% | +14.9% | +14.1% | +13.8% | +22.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | +2.3% | +6.2% | +7.0% | +1.1% | +4.8% |
| EPS Growth (YoY)Latest quarter vs prior year | — | +11.3% | -3.6% | -9.5% | +6.1% |
Valuation Metrics
BIO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 9.1x trailing earnings, BIO trades at a 65% valuation discount to TMO's 26.2x P/E. Adjusting for growth (PEG ratio), A offers better value at 1.72x vs TMO's 12.41x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $401M | $172.8B | $32.7B | $6.9B | $21.6B |
| Enterprise ValueMkt cap + debt − cash | $461M | $203.8B | $34.3B | $7.9B | $22.7B |
| Trailing P/EPrice ÷ TTM EPS | -1.08x | 26.21x | 25.30x | 9.13x | 26.03x |
| Forward P/EPrice ÷ next-FY EPS est. | 69.42x | 18.71x | 19.36x | 27.40x | 27.22x |
| PEG RatioP/E ÷ EPS growth rate | — | 12.41x | 1.72x | — | 6.15x |
| EV / EBITDAEnterprise value multiple | — | 18.72x | 19.41x | 16.53x | 20.01x |
| Price / SalesMarket cap ÷ Revenue | 0.49x | 3.88x | 4.71x | 2.66x | 4.97x |
| Price / BookPrice ÷ Book value/share | 1.09x | 3.27x | 4.87x | 0.93x | 8.13x |
| Price / FCFMarket cap ÷ FCF | — | 27.46x | 28.41x | 18.33x | 23.15x |
Profitability & Efficiency
ILMN leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ILMN delivers a 32.8% return on equity — every $100 of shareholder capital generates $33 in annual profit, vs $-109 for MYGN. BIO carries lower financial leverage with a 0.21x debt-to-equity ratio, signaling a more conservative balance sheet compared to ILMN's 0.94x. On the Piotroski fundamental quality scale (0–9), ILMN scores 8/9 vs BIO's 5/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -109.1% | +13.2% | +18.7% | +2.4% | +32.8% |
| ROA (TTM)Return on assets | -57.4% | +6.4% | +10.1% | +2.2% | +13.4% |
| ROICReturn on invested capital | -8.7% | +7.5% | +13.5% | +2.6% | +16.8% |
| ROCEReturn on capital employed | -9.4% | +9.1% | +14.5% | +2.9% | +17.6% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 6 | 5 | 5 | 8 |
| Debt / EquityFinancial leverage | 0.57x | 0.76x | 0.50x | 0.21x | 0.94x |
| Net DebtTotal debt minus cash | $60M | $31.0B | $1.6B | $999M | $1.1B |
| Cash & Equiv.Liquid assets | $150M | $9.9B | $1.8B | $532M | $1.4B |
| Total DebtShort + long-term debt | $210M | $40.9B | $3.4B | $1.5B | $2.6B |
| Interest CoverageEBIT ÷ Interest expense | -63.57x | 5.89x | 19.53x | -2.49x | 12.09x |
Total Returns (Dividends Reinvested)
Evenly matched — TMO and A and ILMN each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in TMO five years ago would be worth $10,187 today (with dividends reinvested), compared to $1,643 for MYGN. Over the past 12 months, ILMN leads with a +78.3% total return vs BIO's +5.5%. The 3-year compound annual growth rate (CAGR) favors A at -3.6% vs MYGN's -38.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -30.1% | -21.4% | -15.8% | -16.7% | +5.6% |
| 1-Year ReturnPast 12 months | +6.5% | +13.6% | +7.3% | +5.5% | +78.3% |
| 3-Year ReturnCumulative with dividends | -76.6% | -13.4% | -10.5% | -32.8% | -25.4% |
| 5-Year ReturnCumulative with dividends | -83.6% | +1.9% | -8.9% | -57.9% | -61.6% |
| 10-Year ReturnCumulative with dividends | -87.9% | +222.6% | +198.4% | +79.3% | +3.0% |
| CAGR (3Y)Annualised 3-year return | -38.4% | -4.7% | -3.6% | -12.4% | -9.3% |
Risk & Volatility
Evenly matched — BIO and ILMN each lead in 1 of 2 comparable metrics.
Risk & Volatility
BIO is the less volatile stock with a 0.91 beta — it tends to amplify market swings less than MYGN's 1.81 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ILMN currently trades 91.2% from its 52-week high vs MYGN's 49.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.81x | 1.07x | 1.21x | 0.91x | 1.20x |
| 52-Week HighHighest price in past year | $8.59 | $643.99 | $160.27 | $343.12 | $155.53 |
| 52-Week LowLowest price in past year | $3.75 | $385.46 | $106.55 | $211.43 | $75.24 |
| % of 52W HighCurrent price vs 52-week peak | +49.9% | +72.2% | +72.1% | +74.1% | +91.2% |
| RSI (14)Momentum oscillator 0–100 | 35.2 | 43.9 | 54.1 | 36.1 | 59.5 |
| Avg Volume (50D)Average daily shares traded | 1.8M | 1.9M | 1.9M | 304K | 1.5M |
Analyst Outlook
A leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: MYGN as "Hold", TMO as "Buy", A as "Buy", BIO as "Buy", ILMN as "Buy". Consensus price targets imply 43.6% upside for A (target: $166) vs 3.9% for ILMN (target: $147). For income investors, A offers the higher dividend yield at 0.86% vs TMO's 0.36%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $6.00 | $654.67 | $166.00 | $312.50 | $147.38 |
| # AnalystsCovering analysts | 36 | 42 | 38 | 14 | 50 |
| Dividend YieldAnnual dividend ÷ price | — | +0.4% | +0.9% | — | — |
| Dividend StreakConsecutive years of raises | — | 8 | 10 | — | — |
| Dividend / ShareAnnual DPS | — | $1.69 | $0.99 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +1.7% | +1.3% | +4.3% | +3.4% |
ILMN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BIO leads in 1 (Valuation Metrics). 2 tied.
MYGN vs TMO vs A vs BIO vs ILMN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MYGN or TMO or A or BIO or ILMN a better buy right now?
For growth investors, Agilent Technologies, Inc.
(A) is the stronger pick with 6. 7% revenue growth year-over-year, versus -1. 6% for Myriad Genetics, Inc. (MYGN). Bio-Rad Laboratories, Inc. (BIO) offers the better valuation at 9. 1x trailing P/E (27. 4x forward), making it the more compelling value choice. Analysts rate Thermo Fisher Scientific Inc. (TMO) a "Buy" — based on 42 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MYGN or TMO or A or BIO or ILMN?
On trailing P/E, Bio-Rad Laboratories, Inc.
(BIO) is the cheapest at 9. 1x versus Thermo Fisher Scientific Inc. at 26. 2x. On forward P/E, Thermo Fisher Scientific Inc. is actually cheaper at 18. 7x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Agilent Technologies, Inc. wins at 1. 32x versus Thermo Fisher Scientific Inc. 's 8. 86x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — MYGN or TMO or A or BIO or ILMN?
Over the past 5 years, Thermo Fisher Scientific Inc.
(TMO) delivered a total return of +1. 9%, compared to -83. 6% for Myriad Genetics, Inc. (MYGN). Over 10 years, the gap is even starker: TMO returned +222. 6% versus MYGN's -87. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MYGN or TMO or A or BIO or ILMN?
By beta (market sensitivity over 5 years), Bio-Rad Laboratories, Inc.
(BIO) is the lower-risk stock at 0. 91β versus Myriad Genetics, Inc. 's 1. 81β — meaning MYGN is approximately 99% more volatile than BIO relative to the S&P 500. On balance sheet safety, Bio-Rad Laboratories, Inc. (BIO) carries a lower debt/equity ratio of 21% versus 94% for Illumina, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — MYGN or TMO or A or BIO or ILMN?
By revenue growth (latest reported year), Agilent Technologies, Inc.
(A) is pulling ahead at 6. 7% versus -1. 6% for Myriad Genetics, Inc. (MYGN). On earnings-per-share growth, the picture is similar: Illumina, Inc. grew EPS 170. 9% year-over-year, compared to -180. 9% for Myriad Genetics, Inc.. Over a 3-year CAGR, MYGN leads at 6. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MYGN or TMO or A or BIO or ILMN?
Bio-Rad Laboratories, Inc.
(BIO) is the more profitable company, earning 29. 4% net margin versus -44. 4% for Myriad Genetics, Inc. — meaning it keeps 29. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: A leads at 21. 3% versus -8. 2% for MYGN. At the gross margin level — before operating expenses — MYGN leads at 69. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MYGN or TMO or A or BIO or ILMN more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Agilent Technologies, Inc. (A) is the more undervalued stock at a PEG of 1. 32x versus Thermo Fisher Scientific Inc. 's 8. 86x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Thermo Fisher Scientific Inc. (TMO) trades at 18. 7x forward P/E versus 69. 4x for Myriad Genetics, Inc. — 50. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for A: 43. 6% to $166. 00.
08Which pays a better dividend — MYGN or TMO or A or BIO or ILMN?
In this comparison, A (0.
9% yield), TMO (0. 4% yield) pay a dividend. MYGN, BIO, ILMN do not pay a meaningful dividend and should not be held primarily for income.
09Is MYGN or TMO or A or BIO or ILMN better for a retirement portfolio?
For long-horizon retirement investors, Agilent Technologies, Inc.
(A) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 21), 0. 9% yield, +198. 4% 10Y return). Myriad Genetics, Inc. (MYGN) carries a higher beta of 1. 81 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (A: +198. 4%, MYGN: -87. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MYGN and TMO and A and BIO and ILMN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MYGN is a small-cap quality compounder stock; TMO is a mid-cap quality compounder stock; A is a mid-cap quality compounder stock; BIO is a small-cap deep-value stock; ILMN is a mid-cap quality compounder stock. A pays a dividend while MYGN, TMO, BIO, ILMN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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