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4 / 10Stock Comparison
NEPH vs DBVT vs ALKS vs CNMD
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Devices
NEPH vs DBVT vs ALKS vs CNMD — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Medical - Instruments & Supplies | Biotechnology | Biotechnology | Medical - Devices |
| Market Cap | $35M | $1712.35T | $5.90B | $1.17B |
| Revenue (TTM) | $19M | $0.00 | $1.56B | $1.37B |
| Net Income (TTM) | $776K | $-168M | $153M | $55M |
| Gross Margin | 59.2% | — | 65.4% | 53.6% |
| Operating Margin | 3.5% | — | 12.3% | 11.3% |
| Forward P/E | 29.4x | — | 24.8x | 8.7x |
| Total Debt | $1M | $22M | $70M | $835M |
| Cash & Equiv. | $5M | $194M | $1.12B | $41M |
NEPH vs DBVT vs ALKS vs CNMD — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Nephros, Inc. (NEPH) | 100 | 41.4 | -58.6% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Alkermes plc (ALKS) | 100 | 216.4 | +116.4% |
| CONMED Corporation (CNMD) | 100 | 51.9 | -48.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: NEPH vs DBVT vs ALKS vs CNMD
Each card shows where this stock fits in a portfolio — not just who wins on paper.
NEPH carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 0 yrs, beta 0.59
- Rev growth 32.7%, EPS growth -10.1%, 3Y rev CAGR 23.5%
- 2.5% 10Y total return vs ALKS's -11.0%
- Lower volatility, beta 0.59, Low D/E 10.4%, current ratio 4.06x
DBVT is the clearest fit if your priority is momentum.
- +110.4% vs CNMD's -31.3%
ALKS is the clearest fit if your priority is quality.
- 9.8% margin vs DBVT's 0.3%
CNMD is the #2 pick in this set and the best alternative if value and dividends is your priority.
- Lower P/E (8.7x vs 24.8x)
- 2.1% yield; 2-year raise streak; the other 3 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 32.7% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (8.7x vs 24.8x) | |
| Quality / Margins | 9.8% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.59 vs CNMD's 1.34, lower leverage | |
| Dividends | 2.1% yield; 2-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +110.4% vs CNMD's -31.3% | |
| Efficiency (ROA) | 5.9% ROA vs DBVT's -89.0% |
NEPH vs DBVT vs ALKS vs CNMD — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
NEPH vs DBVT vs ALKS vs CNMD — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ALKS leads in 2 of 6 categories
CNMD leads 2 • NEPH leads 0 • DBVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ALKS leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ALKS and DBVT operate at a comparable scale, with $1.6B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to CNMD's 4.0%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $19M | $0 | $1.6B | $1.4B |
| EBITDAEarnings before interest/tax | $806,000 | -$112M | $212M | $219M |
| Net IncomeAfter-tax profit | $776,000 | -$168M | $153M | $55M |
| Free Cash FlowCash after capex | -$348,000 | -$151M | $392M | $124M |
| Gross MarginGross profit ÷ Revenue | +59.2% | — | +65.4% | +53.6% |
| Operating MarginEBIT ÷ Revenue | +3.5% | — | +12.3% | +11.3% |
| Net MarginNet income ÷ Revenue | +4.1% | — | +9.8% | +4.0% |
| FCF MarginFCF ÷ Revenue | -1.8% | — | +25.1% | +9.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +6.9% | — | +28.2% | -0.7% |
| EPS Growth (YoY)Latest quarter vs prior year | -81.0% | +91.5% | -4.1% | +136.8% |
Valuation Metrics
CNMD leads this category, winning 3 of 5 comparable metrics.
Valuation Metrics
At 24.8x trailing earnings, ALKS trades at a 16% valuation discount to NEPH's 29.4x P/E. On an enterprise value basis, CNMD's 10.2x EV/EBITDA is more attractive than NEPH's 23.9x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $35M | $1712.35T | $5.9B | $1.2B |
| Enterprise ValueMkt cap + debt − cash | $31M | $1712.35T | $4.9B | $2.0B |
| Trailing P/EPrice ÷ TTM EPS | 29.36x | -0.76x | 24.76x | 25.22x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 8.71x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 0.69x |
| EV / EBITDAEnterprise value multiple | 23.90x | — | 17.25x | 10.17x |
| Price / SalesMarket cap ÷ Revenue | 1.87x | — | 4.00x | 0.85x |
| Price / BookPrice ÷ Book value/share | 3.47x | 0.66x | 3.28x | 1.15x |
| Price / FCFMarket cap ÷ FCF | 21.32x | — | 12.28x | 7.78x |
Profitability & Efficiency
ALKS leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
ALKS delivers a 8.8% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-130 for DBVT. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to CNMD's 0.81x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs DBVT's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | +7.7% | -130.2% | +8.8% | +5.4% |
| ROA (TTM)Return on assets | +5.9% | -89.0% | +5.4% | +2.4% |
| ROICReturn on invested capital | +14.2% | — | +18.9% | +5.8% |
| ROCEReturn on capital employed | +11.2% | -145.7% | +14.2% | +7.0% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 4 | 7 | 5 |
| Debt / EquityFinancial leverage | 0.10x | 0.13x | 0.04x | 0.81x |
| Net DebtTotal debt minus cash | -$4M | -$172M | -$1.0B | $794M |
| Cash & Equiv.Liquid assets | $5M | $194M | $1.1B | $41M |
| Total DebtShort + long-term debt | $1M | $22M | $70M | $835M |
| Interest CoverageEBIT ÷ Interest expense | 588.00x | -189.82x | 32.30x | 5.20x |
Total Returns (Dividends Reinvested)
Evenly matched — NEPH and ALKS each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ALKS five years ago would be worth $16,091 today (with dividends reinvested), compared to $2,902 for CNMD. Over the past 12 months, DBVT leads with a +110.4% total return vs CNMD's -31.3%. The 3-year compound annual growth rate (CAGR) favors NEPH at 29.4% vs CNMD's -31.1% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -32.0% | +4.9% | +25.3% | -6.0% |
| 1-Year ReturnPast 12 months | +65.6% | +110.4% | +16.5% | -31.3% |
| 3-Year ReturnCumulative with dividends | +116.8% | +19.7% | +14.5% | -67.3% |
| 5-Year ReturnCumulative with dividends | -56.3% | -69.1% | +60.9% | -71.0% |
| 10-Year ReturnCumulative with dividends | +2.5% | -87.0% | -11.0% | +6.6% |
| CAGR (3Y)Annualised 3-year return | +29.4% | +6.2% | +4.6% | -31.1% |
Risk & Volatility
Evenly matched — NEPH and ALKS each lead in 1 of 2 comparable metrics.
Risk & Volatility
NEPH is the less volatile stock with a 0.59 beta — it tends to amplify market swings less than CNMD's 1.34 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs NEPH's 50.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.59x | 1.26x | 1.06x | 1.34x |
| 52-Week HighHighest price in past year | $6.42 | $26.18 | $36.60 | $61.08 |
| 52-Week LowLowest price in past year | $1.83 | $7.53 | $25.17 | $33.21 |
| % of 52W HighCurrent price vs 52-week peak | +50.3% | +76.3% | +96.7% | +62.4% |
| RSI (14)Momentum oscillator 0–100 | 54.3 | 48.1 | 60.2 | 49.6 |
| Avg Volume (50D)Average daily shares traded | 33K | 252K | 2.3M | 406K |
Analyst Outlook
CNMD leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", ALKS as "Buy", CNMD as "Hold". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 24.3% for ALKS (target: $44). CNMD is the only dividend payer here at 2.09% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | — | $46.33 | $44.00 | $78.00 |
| # AnalystsCovering analysts | — | 15 | 28 | 21 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +2.1% |
| Dividend StreakConsecutive years of raises | 0 | 0 | 0 | 2 |
| Dividend / ShareAnnual DPS | — | — | — | $0.79 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.5% | 0.0% |
ALKS leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CNMD leads in 2 (Valuation Metrics, Analyst Outlook). 2 tied.
NEPH vs DBVT vs ALKS vs CNMD: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is NEPH or DBVT or ALKS or CNMD a better buy right now?
For growth investors, Nephros, Inc.
(NEPH) is the stronger pick with 32. 7% revenue growth year-over-year, versus -5. 2% for Alkermes plc (ALKS). Alkermes plc (ALKS) offers the better valuation at 24. 8x trailing P/E, making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — NEPH or DBVT or ALKS or CNMD?
On trailing P/E, Alkermes plc (ALKS) is the cheapest at 24.
8x versus Nephros, Inc. at 29. 4x.
03Which is the better long-term investment — NEPH or DBVT or ALKS or CNMD?
Over the past 5 years, Alkermes plc (ALKS) delivered a total return of +60.
9%, compared to -71. 0% for CONMED Corporation (CNMD). Over 10 years, the gap is even starker: CNMD returned +6. 6% versus DBVT's -87. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — NEPH or DBVT or ALKS or CNMD?
By beta (market sensitivity over 5 years), Nephros, Inc.
(NEPH) is the lower-risk stock at 0. 59β versus CONMED Corporation's 1. 34β — meaning CNMD is approximately 125% more volatile than NEPH relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 81% for CONMED Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — NEPH or DBVT or ALKS or CNMD?
By revenue growth (latest reported year), Nephros, Inc.
(NEPH) is pulling ahead at 32. 7% versus -5. 2% for Alkermes plc (ALKS). On earnings-per-share growth, the picture is similar: Alkermes plc grew EPS -34. 1% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, NEPH leads at 23. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — NEPH or DBVT or ALKS or CNMD?
Alkermes plc (ALKS) is the more profitable company, earning 16.
4% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 16. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALKS leads at 17. 2% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — ALKS leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is NEPH or DBVT or ALKS or CNMD more undervalued right now?
Analyst consensus price targets imply the most upside for DBVT: 131.
8% to $46. 33.
08Which pays a better dividend — NEPH or DBVT or ALKS or CNMD?
In this comparison, CNMD (2.
1% yield) pays a dividend. NEPH, DBVT, ALKS do not pay a meaningful dividend and should not be held primarily for income.
09Is NEPH or DBVT or ALKS or CNMD better for a retirement portfolio?
For long-horizon retirement investors, Nephros, Inc.
(NEPH) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 59)). Both have compounded well over 10 years (NEPH: +2. 5%, DBVT: -87. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between NEPH and DBVT and ALKS and CNMD?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: NEPH is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; ALKS is a small-cap quality compounder stock; CNMD is a small-cap quality compounder stock. CNMD pays a dividend while NEPH, DBVT, ALKS do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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